Article
Chemistry, Medicinal
Chen-Hung Lee, Chien-Hao Huang, Kuo-Chun Hung, Shu-Chun Huang, Chi-Ching Kuo, Shih-Jung Liu
Summary: The inhibition of DPP4 can enhance wound closure in diabetic patients with chronic foot ulcers. Nanofibrous drug-eluting PLGA membranes loaded with vildagliptin can sustainably release the drug, improving the healing of diabetic wounds.
Review
Pharmacology & Pharmacy
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
Summary: Chronic wounds in poorly managed diabetics are difficult to heal due to long-term uncontrolled blood glucose levels. To prevent complications, special medical care is needed. Nanofibrous scaffolds are a promising treatment due to their flexibility, ability to load bioactive compounds, and biomimetic environment for cell proliferation.
Article
Chemistry, Applied
Guangyao Wang, Junwei Ye, Miao Wang, Ye Qi, Siqi Zhang, Lei Shi, Yueguang Fang, Yiming Tian, Guiling Ning
Summary: In this study, a chitosan membrane loaded with copper boron-imidazolate framework (Cu-BIF) was successfully prepared as a wound dressing. The Cu-BIF/CS membrane showed desirable biocompatibility and exhibited antibacterial activity against bacterial infections. It also accelerated wound closure rate and skin regeneration. This research provides important insights for clinical treatment of bacterial-infected wounds.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Sachin Yadav, Dilip Kumar Arya, Prashant Pandey, Sneha Anand, Anurag Kumar Gautam, Shivendu Ranjan, Shubhini A. Saraf, Vijayakumar Mahalingam Rajamanickam, Sanjay Singh, Kumarappan Chidambaram, Taha Alqahtani, Paruvathanahalli Siddalingam Rajinikanth
Summary: Foot ulceration is a severe complication of diabetes leading to lower-extremity amputation. The developed chitosan-polyvinyl alcohol blended electrospun nanofiber loaded with bioactive materials demonstrated efficient diabetic wound healing through sustained release of bioactive molecules, anti-bacterial properties, and acceleration of cell migration and proliferation.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Pharmacology & Pharmacy
Mark David S. Samraj, Selvaraj Dinesh Kirupha, Santhini Elango, Ketankumar Vadodaria
Summary: The research focused on developing a nanofibrous wound healing membrane using curcumin and Indian honey, showcasing antibacterial, antioxidant, biodegradable, and biocompatible properties. Various experiments confirmed the membrane's efficacy in wound healing processes.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Karla A. Barbosa, Isabella C. P. Rodrigues, Leticia Tamborlin, Augusto D. Luchessi, Eder S. N. Lopes, Lais P. Gabriel
Summary: Polymeric membranes are a promising alternative to conventional dressings for wound-healing applications. This study successfully produced and characterized poly(L-lactic acid) membranes incorporated with curcumin particles using rotary jet spinning technique. The membranes demonstrated thermal stability, adequate mechanical strength, low degradation rates, and sustained release of curcumin.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Review
Materials Science, Multidisciplinary
Zijian Wang, Weikang Hu, Wang Wang, Yu Xiao, Yun Chen, Xinghuan Wang
Summary: This review summarizes the impact of bacterial infection on wound healing and presents the latest advances in antibacterial nanofibrous materials for accelerating the healing process. By incorporating substances such as antibiotics, antimicrobial peptides, metals, and antibacterial polymers into ENMs, the antibacterial activity of ENMs is enhanced.
ADVANCED FIBER MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Dan Xia, Yuan Liu, Wuxiu Cao, Junwei Gao, Donghui Wang, Mengxia Lin, Chunyong Liang, Ning Li, Ruodan Xu
Summary: Coaxial electrospinning nanofibrous patches combining anti-bacterial and anti-inflammation agents have the potential to accelerate wound healing, which is achieved through co-loading and sequential release of drugs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Wei Zhang, Xue Guan, Xiao Qiu, Tonghuan Gao, Wanying Yu, Mengyuan Zhang, Liru Song, Dan Liu, Jidong Dong, Zaixing Jiang, Dawei Zhang
Summary: In this study, skin-inspired multilayer Janus composite nanofibrous membranes were designed and prepared as wound dressings with superhydrophilicity and superhydrophobicity. The membranes were investigated for their wettability, morphology, in-vitro release, cytotoxicity, antimicrobial activity, and healing effect. Results from animal experiments and histological analysis demonstrated that the composite membranes were more effective in improving the healing of full-thickness defect wounds and promoting the growth of collagen fibers and collagen deposition. The composite membranes consisted of a drug-loading layer with a superhydrophilic surface for self-pumping and drugs backflow, a hydrophobic polyvinylidene fluoride layer for delaying exudates loss, and a superhydrophobic coating with self-cleaning properties for avoiding the adhesion of foreign microorganisms.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Xihao Tang, Xiangji Liao, Xinting Cai, Jialin Wu, Xueying Wu, Qianni Zhang, Yilun Yan, Shengrun Zheng, Huawei Jiang, Jun Fan, Songliang Cai, Weiguang Zhang, Yi Liu
Summary: Two chiral covalent organic frameworks (COFs) with well-defined one-handed double-helical nanofibrous morphologies were successfully constructed using a template-free method based on the diastereoselective formation of aminal linkages. Time-dependent experiments revealed the spontaneous transformation of initial rod-like aggregates into the double-helical microstructures. The helical chirality and circular dichroism signal can be easily reversed by adjusting the amount of acetic acid during synthesis. Furthermore, the helical COF nanostructures were able to induce circularly polarized luminescence with a high luminescent asymmetric factor (g(lum)) of approximately 0.01 by transferring chirality to achiral fluorescent molecular adsorbents.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Environmental
M. Roopesh, M. S. Jyothi, Rajendran Velmurugan, Gurumurthy Hegde, Khantong Soontarapa, Rangappa S. Keri
Summary: Biowaste-derived carbon biomaterial scaffolds loaded with curcumin have been used for wound healing. The scaffolds exhibited desirable drug release properties, antibacterial activity, and the ability to promote skin reconstruction.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Polymer Science
Dongwei Lan, Yuqin Zhang, Haiqiang Zhang, Jiale Zhou, Xiang Chen, Zhi Li, Fangyin Dai
Summary: The novel wound dressing prepared by mixing natural Manuka honey, silk fibroin, and polycaprolactone showed excellent antimicrobial properties and cytocompatibility, offering potential for accelerating wound healing.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Kelcilene Bruna Ricardo Teodoro, Augusto Duarte Alvarenga, Luis Fernando Rocha Oliveira, Paulo Augusto Marques Chagas, Raphael Guimaraes Lopes, Rafaela da Silveira Andre, Luiza Amim Mercante, Fernanda Alves, Mirian Denise Stringasci, Hilde Harb Buzza, Natalia Mayumi Inada, Daniel Souza Correa
Summary: In this study, a low-cost multifunctional wound dressing was designed by loading curcumin (CC) into poly(epsilon-caprolactone) (PCL) nanofibers using solution blow spinning (SBS) technique. The PCL/CC bandages exhibited various functions, including controlled release of CC, colorimetric indication of wound conditions, microbial barrier, biocompatibility, and a platform for antimicrobial photodynamic therapy (aPDT). The findings indicate the potential of using PCL and CC to produce biocompatible and multifunctional wound dressings.
ACS APPLIED BIO MATERIALS
(2023)
Review
Chemistry, Applied
Shuang Hao, Zhiqian Jia
Summary: In recent years, covalent organic frameworks (COFs) have gained considerable attention due to their remarkable characteristics, such as well-ordered pore channels and easy functionalization. This review article provides a comprehensive overview of the latest breakthroughs in COF membranes and discusses the various fabrication methods used, as well as the applications and future challenges in this field.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Chemistry, Physical
Mengna Dong, Xinyu Sun, Lihua Li, Kunyi He, Jiao Wang, Hui Zhang, Li Wang
Summary: In this study, a bacteria-triggered wearable film-based band-aid was developed for monitoring and treating wound infection. The band-aid can detect and control infection quickly through color changes and photothermal/photodynamic therapy, and showed promising therapeutic effects in experiments.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Kailun Chen, Hui Zhang
ACS APPLIED MATERIALS & INTERFACES
(2020)
Review
Food Science & Technology
Cen Zhang, Yang Li, Peng Wang, Hui Zhang
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2020)
Article
Food Science & Technology
Abdullah, Jochen Weiss, Hui Zhang
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2020)
Review
Food Science & Technology
Abdullah, Jochen Weiss, Talha Ahmad, Cen Zhang, Hui Zhang
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2020)
Review
Food Science & Technology
Marium Waheed, Muhammad Yousaf, Aamir Shehzad, Muhammad Inam-Ur-Raheem, Muhammad Kashif Iqbal Khan, Moazzam Rafiq Khan, Naveed Ahmad, Abdullah, Rana Muhammad Aadil
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2020)
Review
Food Science & Technology
Shahzad Farooq, Abdullah, Hui Zhang, Jochen Weiss
Summary: This article highlights the importance of utilizing natural phenolic antioxidants to inhibit lipid oxidation in emulsified food products, discussing the complexity of their inhibition mechanism and recent progress on modifying the polarity of antioxidants. It also elaborates on the partitioning behavior of phenolic antioxidants at the oil-water interface and the emerging phenolic antioxidants applied in food emulsions, emphasizing the interactions of polar-nonpolar antioxidants as a promising strategy for improved oxidative stability of emulsions.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Review
Food Science & Technology
Abdullaha, YuCheng Zou, Shahzad Farooq, Noman Walayat, Hui Zhang, Marco Faieta, Paola Pittia, Qingrong Huang
Summary: Bio-aerogels, as a sustainable biomaterial, have unique characteristics and find various applications in the food industry.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Cen Zhang, Peng Wang, Jiawen Li, Hui Zhang, Jochen Weiss
Summary: Core-shell nanofibers were electrospun from bilayer gelatin/gum arabic corn oil-in-water emulsions crosslinked by genipin, resulting in improved surface hydrophobic and mechanical properties. The crosslinking increased the stability of the emulsions, facilitating bioactive encapsulation and controlled release of active substances.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Peng Wang, Cen Zhang, Yucheng Zou, Yang Li, Hui Zhang
Summary: In this study, lysozyme and dextran sulfate sodium salt were alternately deposited on electrospun cellulose acetate nanofibers and crosslinked via Maillard reaction, resulting in improved thermal stability and antibacterial activities. The immobilized lysozyme maintained high activity after heating and the nanofibrous mats exhibited enhanced antibacterial effects against Staphylococcus aureus and Escherichia coli.
FOOD HYDROCOLLOIDS
(2021)
Review
Food Science & Technology
Muhammad Ijaz Ahmad, Shahzad Farooq, Yasmin Alhamoud, Chunbao Li, Hui Zhang
Summary: This review discusses the historical perspective, nutritional composition, and functional properties of mycoprotein as a meat alternative. It also summarizes the methods of extracting mycoprotein from agro-industrial waste and highlights the health effects of mycoprotein consumption.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Yucheng Zou, Junjie Weng, Zeyu Qin, Yipeng Zhang, Shengyang Ji, Hui Zhang
Summary: In this study, we developed a smart nanoplatform that is responsive to pH and light, using nanofiber membrane structure incorporated with PQ, ZIF-8, and GQDs to achieve efficient antibacterial activity. The synergistic effect of NAR and photoinduced ROS improved the antibacterial efficacy of the nanofiber membranes, which also showed non-toxicity and good biocompatibility.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Food Science & Technology
Muhammad Ijaz Ahmad, Shahzad Farooq, Yasmin Alhamoud, Chunbao Li, Hui Zhang
Summary: This paper focuses on the structure and production stages of LegH preparation as well as its safety and food applications. Although there is still limited research on LegH, it has great potential in developing meat analogs with enhanced flavor and color.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Qinbo Jiang, Meiyu Chen, Zeyu Qin, Jiawen Li, Hui Zhang
Summary: Facile gelation and degelation have been achieved through dynamic hydrogen bonding involving dimethyl sulfoxide, water, and polyethylene glycol. The resulting organohydrogels are anti-freezing, drying-resistant, strongly thixotropic, and water-sensitive, making them significant for biomaterial protection and storage.
CHEMICAL COMMUNICATIONS
(2023)
Review
Chemistry, Applied
Shahzad Farooq, Muhammad Ijaz Ahmad, Usman Ali, Yang Li, Shixiu Cui, Hui Zhang
Summary: This review provides a concise overview of the various analytical techniques employed to assess the authenticity, quality, and potential adulteration of camellia oil. Traditional chromatographic techniques are time-consuming and laborious, while spectroscopic techniques combined with chemometric analyses have emerged as reliable, rapid, simple, sensitive, and accurate alternative analytical tools for the quality control of camellia oil.
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
(2023)
