标题
Discovery of a cooperative mode of inhibiting RIPK1 kinase
作者
关键词
-
出版物
Cell Discovery
Volume 7, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-06-02
DOI
10.1038/s41421-021-00278-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Detecting Protein–Small Molecule Interactions Using Limited Proteolysis–Mass Spectrometry (LiP-MS)
- (2020) Monika Pepelnjak et al. TRENDS IN BIOCHEMICAL SCIENCES
- Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target
- (2020) Lauren Mifflin et al. NATURE REVIEWS DRUG DISCOVERY
- Death by inflammation: drug makers chase the master controller
- (2019) Cormac Sheridan NATURE BIOTECHNOLOGY
- Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
- (2019) Glenn R. Masson et al. NATURE METHODS
- Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis
- (2018) Huyan Meng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases
- (2018) Junying Yuan et al. NATURE REVIEWS NEUROSCIENCE
- Necroptosis activation in Alzheimer's disease
- (2017) Antonella Caccamo et al. NATURE NEUROSCIENCE
- Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry
- (2017) Simone Schopper et al. Nature Protocols
- RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease
- (2017) Dimitry Ofengeim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability
- (2017) Pascal Leuenberger et al. SCIENCE
- Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes
- (2016) Robert Roskoski PHARMACOLOGICAL RESEARCH
- RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS
- (2016) Yasushi Ito et al. SCIENCE
- Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling
- (2016) Nieves Peltzer et al. TRENDS IN CELL BIOLOGY
- Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors
- (2015) Peter Canning et al. CHEMISTRY & BIOLOGY
- Gaussian Accelerated Molecular Dynamics: Unconstrained Enhanced Sampling and Free Energy Calculation
- (2015) Yinglong Miao et al. Journal of Chemical Theory and Computation
- Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1
- (2015) Malek Najjar et al. Cell Reports
- Activation of Necroptosis in Multiple Sclerosis
- (2015) Dimitry Ofengeim et al. Cell Reports
- Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
- (2014) Apostolos Polykratis et al. JOURNAL OF IMMUNOLOGY
- RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity
- (2014) Pratyusha Mandal et al. MOLECULAR CELL
- RIPK3 as a potential therapeutic target for Gaucher's disease
- (2014) Einat B Vitner et al. NATURE MEDICINE
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- Structural Basis of RIP1 Inhibition by Necrostatins
- (2013) Tian Xie et al. STRUCTURE
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
- (2012) A Degterev et al. CELL DEATH AND DIFFERENTIATION
- Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
- (2012) N Takahashi et al. Cell Death & Disease
- RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
- (2011) Linde Duprez et al. IMMUNITY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Hydrogen exchange mass spectrometry for studying protein structure and dynamics
- (2010) Lars Konermann et al. CHEMICAL SOCIETY REVIEWS
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
- (2009) D.-W. Zhang et al. SCIENCE
- Identification of RIP1 kinase as a specific cellular target of necrostatins
- (2008) Alexei Degterev et al. Nature Chemical Biology
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