Hydrogen exchange mass spectrometry for studying protein structure and dynamics

Hydrogen exchange mass spectrometry: what is it and what can it tell us?

(2010) Sean R. Marcsisin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Effective Removal of Nonionic Detergents in Protein Mass Spectrometry, Hydrogen/Deuterium Exchange, and Proteomics

(2010) Martial Rey et al.   ANALYTICAL CHEMISTRY

Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange

(2010) Xi Zhang et al.   ANALYTICAL CHEMISTRY

Simultaneous Reduction and Digestion of Proteins with Disulfide Bonds for Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry

(2010) Hui-Min Zhang et al.   ANALYTICAL CHEMISTRY

Online, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry

(2010) Lisa M. Jones et al.   ANALYTICAL CHEMISTRY

Advantages of Isotopic Depletion of Proteins for Hydrogen/Deuterium Exchange Experiments Monitored by Mass Spectrometry

(2010) George M. Bou-Assaf et al.   ANALYTICAL CHEMISTRY

Characterizing Short-Lived Protein Folding Intermediates by Top-Down Hydrogen Exchange Mass Spectrometry

(2010) Jingxi Pan et al.   ANALYTICAL CHEMISTRY

Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry

(2010) Christine M. Hebling et al.   ANALYTICAL CHEMISTRY

Rational Manipulation of Amyloidogenesis Using an Atomic Level Map of Peptide−Fibril Interactions

(2010) Yanfang Liang et al.   BIOCHEMISTRY

Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

(2010) Melissa J. Bennett et al.   CHEMISTRY & BIOLOGY

A Medicinal Chemist’s Guide to Molecular Interactions

(2010) Caterina Bissantz et al.   JOURNAL OF MEDICINAL CHEMISTRY

The mobile proton hypothesis in fragmentation of protonated peptides: A perspective

(2010) Robert Boyd et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

Mass spectrometry in high-throughput proteomics: ready for the big time

(2010) Tommy Nilsson et al.   NATURE METHODS

Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy

(2010) C. Eichmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quench-flow experiments combined with mass spectrometry show apomyoglobin folds through an obligatory intermediate

(2010) Vickie Tsui et al.   PROTEIN SCIENCE

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Atomic-Level Characterization of the Structural Dynamics of Proteins

(2010) D. E. Shaw et al.   SCIENCE

A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution

(2010) Dmitry M. Korzhnev et al.   SCIENCE

H/D Exchange and Mass Spectrometry in the Studies of Protein Conformation and Dynamics: Is There a Need for a Top-Down Approach?

(2009) Igor A. Kaltashov et al.   ANALYTICAL CHEMISTRY

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Gas-Phase Hydrogen/Deuterium Exchange in a Traveling Wave Ion Guide for the Examination of Protein Conformations

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS

(2009) John R. Engen   ANALYTICAL CHEMISTRY

Collisions or Electrons? Protein Sequence Analysis in the 21st Century

(2009) Joshua J. Coon   ANALYTICAL CHEMISTRY

Phosphorylation-Induced Activation of the Response Regulator VraR from Staphylococcus aureus: Insights from Hydrogen Exchange Mass Spectrometry

(2009) Yu-Hong Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein

(2009) Jingxi Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry

(2009) Igor A. Kaltashov et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enzyme millisecond conformational dynamics do not catalyze the chemical step

(2009) A. V. Pisliakov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry

(2009) Palaniappan Sevugan Chetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A unified model of protein dynamics

(2009) H. Frauenfelder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of CASP8 structure predictions for template free targets

(2009) Moshe Ben-David et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Recombinant immobilized rhizopuspepsin as a new tool for protein digestion in hydrogen/deuterium exchange mass spectrometry

(2009) Martial Rey et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Foldamers with Heterogeneous Backbones

(2008) W. Seth Horne et al.   ACCOUNTS OF CHEMICAL RESEARCH

Restraining Expansion of the Peak Envelope in H/D Exchange-MS and Its Application in Detecting Perturbations of Protein Structure/Dynamics

(2008) Gordon W. Slysz et al.   ANALYTICAL CHEMISTRY

A Brief History of Mass Spectrometry

(2008) Jennifer Griffiths   ANALYTICAL CHEMISTRY

Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches

(2008) Lars Konermann et al.   JOURNAL OF MASS SPECTROMETRY

Electron Capture Dissociation Proceeds with a Low Degree of Intramolecular Migration of Peptide Amide Hydrogens

(2008) Kasper D. Rand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Throughput and Efficiency of a Mass Spectrometry-Based Screening Assay for Protein–Ligand Binding Detection

(2008) E HOPPER et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Probing protein structure by amino acid-specific covalent labeling and mass spectrometry

(2008) Vanessa Leah Mendoza et al.   MASS SPECTROMETRY REVIEWS

From the first protein structures to our current knowledge of protein folding: delights and scepticisms

(2008) Alan R. Fersht   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Specificity of immobilized porcine pepsin in H/D exchange compatible conditions

(2008) Yoshitomo Hamuro et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Problem Solved* (*sort of)

(2008) R. F. Service   SCIENCE