Potential Therapeutic Targets and Vaccine Development for SARS-CoV-2/COVID-19 Pandemic Management: A Review on the Recent Update

Looking beyond COVID-19 vaccine phase 3 trials

(2021) Jerome H. Kim et al.   NATURE MEDICINE

Weather Variability and COVID-19 Transmission: A Review of Recent Research

(2021) Hannah McClymont et al.   International Journal of Environmental Research and Public Health

Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses OC43 and 229E

(2021) Kathryn E Kistler et al.   eLife

Review on Up-to-Date Status of Candidate Vaccines for COVID-19 Disease

(2021) Tafere Mulaw Belete   Infection and Drug Resistance

A Rapid Systematic Review of Public Responses to Health Messages Encouraging Vaccination against Infectious Diseases in a Pandemic or Epidemic

(2021) Sadie Lawes-Wickwar et al.   Vaccines

In high-risk adults, the Moderna vaccine had 94% efficacy against COVID-19 ≥14 d after the 2nd dose

(2021) Zain Chagla   ANNALS OF INTERNAL MEDICINE

The BNT162b2 (BioNTech/Pfizer) vaccine had 95% efficacy against COVID-19 ≥7 days after the 2nd dose

(2021) Zain Chagla   ANNALS OF INTERNAL MEDICINE

Extremely potent human monoclonal antibodies from COVID-19 convalescent patients

(2021) Emanuele Andreano et al.   CELL

Emergence of a Novel SARS-CoV-2 Variant in Southern California

(2021) Wenjuan Zhang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID‐19

(2021) Hatem Elalfy et al.   JOURNAL OF MEDICAL VIROLOGY

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

(2021) Denis Y Logunov et al.   LANCET

COVID vaccines and safety: what the research says

(2021) Ariana Remmel   NATURE

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

(2021) Pengfei Wang et al.   NATURE

Synthetic Messenger RNA-Based Vaccines: From Scorn to Hype

(2021) Steve Pascolo   Viruses-Basel

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

(2021) Hanjun Zhao et al.   Nature Communications

COVID-19 vaccines: rapid development, implications, challenges and future prospects

(2021) Shivaji Kashte et al.   Human Cell

An Update on Antiviral Therapy Against SARS-CoV-2: How Far Have We Come?

(2021) Omkar Indari et al.   Frontiers in Pharmacology

A review of the presence of SARS-CoV-2 RNA in wastewater and airborne particulates and its use for virus spreading surveillance

(2021) Uttpal Anand et al.   ENVIRONMENTAL RESEARCH

SARS-CoV-2 vaccines: Lights and shadows

(2021) Fabio Angeli et al.   European Journal of Internal Medicine

Production of hyperimmune anti-SARS-CoV-2 intravenous immunoglobulin from pooled COVID-19 convalescent plasma

(2021) Shaukat Ali et al.   Immunotherapy

SARS-CoV-2 variants and convalescent plasma: reality, fallacies, and opportunities

(2021) Arturo Casadevall et al.   JOURNAL OF CLINICAL INVESTIGATION

COVID-19 dynamics after a national immunization program in Israel

(2021) Hagai Rossman et al.   NATURE MEDICINE

Tracking the emergence of new SARS-CoV-2 variants in South Africa

(2021) Anise N. Happi et al.   NATURE MEDICINE

Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk assessment for antibody‐based Covid‐19 therapeutics and vaccines

(2021) Daniele Focosi et al.   REVIEWS IN MEDICAL VIROLOGY

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

(2021) Nuno R. Faria et al.   SCIENCE

A human coronavirus evolves antigenically to escape antibody immunity

(2021) Rachel T. Eguia et al.   PLoS Pathogens

A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development

(2021) Yingzhu Li et al.   ACS Central Science

Factors Influencing the Efficacy of COVID-19 Vaccines: A Quantitative Synthesis of Phase III Trials

(2021) Luigino Calzetta et al.   Vaccines

Mini-Review Discussing the Reliability and Efficiency of COVID-19 Vaccines

(2021) Bogdan Doroftei et al.   Diagnostics

Novel coronavirus disease 2019 (COVID-19) pandemic: From transmission to control with an interdisciplinary vision

(2021) Uttpal Anand et al.   ENVIRONMENTAL RESEARCH

Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study

(2021) Wan Ni Chia et al.   Lancet Microbe

Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China

(2020) Jin-jin Zhang et al.   ALLERGY

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients

(2020) Zijie Shen et al.   CLINICAL INFECTIOUS DISEASES

Recent discovery and development of inhibitors targeting coronaviruses

(2020) Thanigaimalai Pillaiyar et al.   DRUG DISCOVERY TODAY

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Presumed Asymptomatic Carrier Transmission of COVID-19

(2020) Yan Bai et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

Antimicrobial host defence peptides: functions and clinical potential

(2020) Neeloffer Mookherjee et al.   NATURE REVIEWS DRUG DISCOVERY

Outbreak of a novel coronavirus

(2020) Andrea Du Toit   NATURE REVIEWS MICROBIOLOGY

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Why does COVID-19 disproportionately affect older people?

(2020) Amber L. Mueller et al.   Aging-US

A potential role for integrins in host cell entry by SARS-CoV-2

(2020) Christian JA Sigrist et al.   ANTIVIRAL RESEARCH

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

(2020) Yvan Jamilloux et al.   AUTOIMMUNITY REVIEWS

Repositioning PARP inhibitors for SARS‐CoV‐2 infection (COVID‐19); a new multi‐pronged therapy for ARDS?

(2020) Nicola Curtin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study

(2020) Peter Jüni et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

(2020) Daniel Wrapp et al.   CELL

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

(2020) Young-Il Kim et al.   Cell Host & Microbe

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

(2020) Annsea Park et al.   Cell Host & Microbe

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

(2020) Wanbo Tai et al.   Cellular & Molecular Immunology

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

(2020) Chunyan Yi et al.   Cellular & Molecular Immunology

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

(2020) Daniel Batlle et al.   CLINICAL SCIENCE

No association of COVID-19 transmission with temperature or UV radiation in Chinese cities

(2020) Ye Yao et al.   EUROPEAN RESPIRATORY JOURNAL

Understanding SARS‐CoV‐2 endocytosis for COVID‐19 drug repurposing

(2020) Oleg O. Glebov   FEBS Journal

Human Intestinal Defensin 5 Inhibits SARS-CoV-2 Invasion by Cloaking ACE2

(2020) Cheng Wang et al.   GASTROENTEROLOGY

Generation and Characterization of Single Chain Variable Fragment against Alpha-Enolase of Candida albicans

(2020) Sy-Jye Leu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target

(2020) Mohamed Abu-Farha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Review of SARS-CoV-2 and the Ongoing Clinical Trials

(2020) Yung-Fang Tu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antiviral Peptides: Identification and Validation

(2020) Garima Agarwal et al.   International Journal of Peptide Research and Therapeutics

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

(2020) James M. Sanders et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

(2020) Anwarul Hasan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The convalescent sera option for containing COVID-19

(2020) Arturo Casadevall et al.   JOURNAL OF CLINICAL INVESTIGATION

Phylogenetic Analysis and Structural Modeling of SARS-CoV-2 Spike Protein Reveals an Evolutionary Distinct and Proteolytically Sensitive Activation Loop

(2020) Javier A. Jaimes et al.   JOURNAL OF MOLECULAR BIOLOGY

Why tocilizumab could be an effective treatment for severe COVID-19?

(2020) Binqing Fu et al.   Journal of Translational Medicine

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

(2020) Sin Fun Sia et al.   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins

(2020) Kangpeng Xiao et al.   NATURE

Infection of dogs with SARS-CoV-2

(2020) Thomas H. C. Sit et al.   NATURE

Antibody responses to SARS-CoV-2 in patients with COVID-19

(2020) Quan-Xin Long et al.   NATURE MEDICINE

Transmission of SARS-CoV-2 in Domestic Cats

(2020) Peter J. Halfmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019

(2020) Ashley Barlow et al.   PHARMACOTHERAPY

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COVID-19 and the male susceptibility: the role of ACE2, TMPRSS2 and the androgen receptor

(2020) Georges Mjaess et al.   PROGRES EN UROLOGIE

SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells

(2020) Jingfang Mu et al.   Science China-Life Sciences

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

(2020) Timothy P. Sheahan et al.   Science Translational Medicine

Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research

(2020) Mahesh V. Madhavan et al.   THROMBOSIS AND HAEMOSTASIS

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

(2020) Hongzhou Lu   BioScience Trends

Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps

(2020) Jonathan Whisenant et al.   ACS Medicinal Chemistry Letters

A human monoclonal antibody blocking SARS-CoV-2 infection

(2020) Chunyan Wang et al.   Nature Communications

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?

(2020) Konrad H. Stopsack et al.   Cancer Discovery

Repurposing antimalarials and other drugs for COVID-19

(2020) Patricia Schlagenhauf et al.   Travel Medicine and Infectious Disease

Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)?

(2020) Ping Liu et al.   PLoS Pathogens

Commentary: Origin and evolution of pathogenic coronaviruses

(2020) Shun Adachi et al.   Frontiers in Immunology

Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets?

(2020) Jean-Michel Sallenave et al.   Frontiers in Immunology

Medical treatment options for COVID-19

(2020) Leen Delang et al.   European Heart Journal-Acute Cardiovascular Care

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

(2020) Yuan Huang et al.   ACTA PHARMACOLOGICA SINICA

COVID‐19 and Treg/Th17 imbalance: Potential relationship to pregnancy outcomes

(2020) Kahinho P. Muyayalo et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Clinical trials of repurposed antivirals for SARS-CoV-2

(2020) Miguel Angel Martinez   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potential Role of Anti-interleukin (IL)-6 Drugs in the Treatment of COVID-19: Rationale, Clinical Evidence and Risks

(2020) Salvatore Crisafulli et al.   BIODRUGS

COVID19 inhibitors: A prospective therapeutics

(2020) Md Jawaid Akhtar   BIOORGANIC CHEMISTRY

The genetic sequence, origin, and diagnosis of SARS-CoV-2

(2020) Huihui Wang et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

COVID-19 conundrum: Clinical phenotyping based on pathophysiology as a promising approach to guide therapy in a novel illness

(2020) Robin Cherian et al.   EUROPEAN RESPIRATORY JOURNAL

Antibody-based immunotherapeutics and use of convalescent plasma to counter COVID-19: advances and prospects

(2020) Khan Sharun et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

An approach towards development of monoclonal IgY antibodies against SARS CoV-2 spike protein (S) using phage display method: A review

(2020) Rajeswari Somasundaram et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Monoclonal Antibodies for Prevention and Treatment of COVID-19

(2020) Mary Marovich et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Drug targets for COVID-19 therapeutics: Ongoing global efforts

(2020) Ambrish Saxena   JOURNAL OF BIOSCIENCES

COVID-19: Drug Targets and Potential Treatments

(2020) Carmen Gil et al.   JOURNAL OF MEDICINAL CHEMISTRY

p38 MAPK inhibition: A promising therapeutic approach for COVID-19

(2020) Joseph M. Grimes et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Vaccines for COVID-19: The current state of play

(2020) Archana Koirala et al.   Paediatric Respiratory Reviews

Drugs against SARS‐CoV ‐2: What do we know about their mode of action?

(2020) Coralie Valle et al.   REVIEWS IN MEDICAL VIROLOGY

Infusion of Convalescent Plasma is Associated with Clinical Improvement in Critically Ill Patients with COVID-19: A Pilot Study

(2020) Juan C. Olivares-Gazca et al.   Revista de Investigacion Clinica-Clinical and Translational Investigation

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

(2020) Alina Baum et al.   SCIENCE

Effects of temperature and humidity on the daily new cases and new deaths of COVID-19 in 166 countries

(2020) Yu Wu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

COVID-19 transmission in Mainland China is associated with temperature and humidity: A time-series analysis

(2020) Hongchao Qi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Identification of a Potential Peptide Inhibitor of SARS-CoV-2 Targeting its Entry into the Host Cells

(2020) Mirza S. Baig et al.   DRUGS IN R&D

Interplay between SARS-CoV-2 and the type I interferon response

(2020) Margarida Sa Ribero et al.   PLoS Pathogens

Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2

(2020) Intikhab Alam et al.   Frontiers in Cellular and Infection Microbiology

Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention

(2020) John P. Hussman   Frontiers in Pharmacology

Comorbidity Assessment Is Essential During COVID-19 Treatment

(2020) Shweta Jakhmola et al.   Frontiers in Physiology

Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies

(2020) Aldo Bonaventura et al.   Frontiers in Immunology

SARS-CoV-2: Repurposed Drugs and Novel Therapeutic Approaches—Insights into Chemical Structure—Biological Activity and Toxicological Screening

(2020) Cristina Adriana Dehelean et al.   Journal of Clinical Medicine

RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery

(2020) Wei Zhu et al.   SLAS Discovery

A Multi-Targeting Approach to Fight SARS-CoV-2 Attachment

(2020) Luciano Pirone et al.   Frontiers in Molecular Biosciences

Potential of DNA Intercalating Alkaloids and Other Plant Secondary Metabolites against SARS-CoV-2 Causing COVID-19

(2020) Michael Wink   Diversity-Basel

Analysis of Possible Intermediate Hosts of the New Coronavirus SARS-CoV-2

(2020) Shu Yuan et al.   Frontiers in Veterinary Science

Existing highly accumulating lysosomotropic drugs with potential for repurposing to target COVID-19

(2020) Ulf Norinder et al.   BIOMEDICINE & PHARMACOTHERAPY

Potential small‐molecule drugs as available weapons to fight novel coronavirus ( 2019‐nCoV ): A review

(2020) Vahid Rahimkhoei et al.   CELL BIOCHEMISTRY AND FUNCTION

COVID-19 update: The race to therapeutic development

(2020) Julianne D. Twomey et al.   DRUG RESISTANCE UPDATES

Targeting the SphK-S1P-SIPR Pathway as a Potential Therapeutic Approach for COVID-19

(2020) Eileen M McGowan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study

(2020) Barnaby E Young et al.   LANCET

Heparin-binding Peptides as Novel Therapies to Stop SARS-CoV-2 Cellular Entry and Infection

(2020) Omid Tavassoly et al.   MOLECULAR PHARMACOLOGY

Artificial intelligence, drug repurposing and peer review

(2020) Jeremy M. Levin et al.   NATURE BIOTECHNOLOGY

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

(2020) Yanchun Peng et al.   NATURE IMMUNOLOGY

SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition

(2020) Annika Nelde et al.   NATURE IMMUNOLOGY

Effects of temperature and humidity on the spread of COVID-19: A systematic review

(2020) Paulo Mecenas et al.   PLoS One

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Antiviral activity of digoxin and ouabain against SARS-CoV-2 infection and its implication for COVID-19

(2020) Junhyung Cho et al.   Scientific Reports

COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

(2020) Anshumali Mittal et al.   PLoS Pathogens

The Potential of Antiviral Peptides as COVID-19 Therapeutics

(2020) Arun Suria Karnan Mahendran et al.   Frontiers in Pharmacology

Human recombinant soluble ACE2 in severe COVID-19

(2020) Alexander Zoufaly et al.   Lancet Respiratory Medicine

Immunomodulatory Role of the Antimicrobial LL-37 Peptide in Autoimmune Diseases and Viral Infections

(2020) Bapi Pahar et al.   Vaccines

Can Immunization of Hens Provide Oral-Based Therapeutics against COVID-19?

(2020) José M. Pérez de la Lastra et al.   Vaccines

Progress in Developing Inhibitors of SARS-CoV-2 3C-Like Protease

(2020) Qingxin Li et al.   Microorganisms

Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update

(2020) David Balgoma et al.   Metabolites

Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit?

(2020) Amani Audi et al.   Frontiers in Public Health

Ligand-based approach for predicting drug targets and for virtual screening against COVID-19

(2020) Yanqing Yang et al.   BRIEFINGS IN BIOINFORMATICS

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses

(2020) Anna Artese et al.   DRUG RESISTANCE UPDATES

A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness

(2020) Sabeena Ahmed et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Potential immuno-nanomedicine strategies to fight COVID-19 like pulmonary infections

(2020) Srinivasa Reddy Bonam et al.   Nano Today

Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

(2019) Ruben J. G. Hulswit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses

(2019) Liang Shen et al.   JOURNAL OF VIROLOGY

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

(2019) Shuai Xia et al.   Science Advances

Mini review on Antimicrobial Peptides, Sources, Mechanism and Recent Applications

(2019) Jaspreet Kaur Boparai et al.   PROTEIN AND PEPTIDE LETTERS

Recombinant helical plant virus-based nanoparticles for vaccination and immunotherapy

(2018) Kannan Badri Narayanan et al.   VIRUS GENES

The prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) antibodies in dromedary camels in Israel

(2018) Jennifer L. Harcourt et al.   Zoonoses and Public Health

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Newcastle disease virus (NDV) recombinant expressing the hemagglutinin of H7N9 avian influenza virus protects chickens against NDV and highly pathogenic avian influenza A (H7N9) virus challenges

(2017) Zenglei Hu et al.   VACCINE

Receptor-binding loops in alphacoronavirus adaptation and evolution

(2017) Alan H. M. Wong et al.   Nature Communications

Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation

(2016) Heather W. Stout-Delgado et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Coronaviruses — drug discovery and therapeutic options

(2016) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

(2016) Shuo Su et al.   TRENDS IN MICROBIOLOGY

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

(2016) Yunjeong Kim et al.   PLoS Pathogens

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Atlas of Mexican Triatominae (Reduviidae: Hemiptera) and vector transmission of Chagas disease

(2015) Janine M Ramsey et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Genomic Analysis of 15 Human Coronaviruses OC43 (HCoV-OC43s) Circulating in France from 2001 to 2013 Reveals a High Intra-Specific Diversity with New Recombinant Genotypes

(2015) Nathalie Kin et al.   Viruses-Basel

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

(2014) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus

(2014) M. Cotten et al.   mBio

Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia

(2014) A. N. Alagaili et al.   mBio

Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013

(2013) M Hemida et al.   Eurosurveillance

Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013

(2013) R Perera et al.   Eurosurveillance

Genetic Characterization of Betacoronavirus Lineage C Viruses in Bats Reveals Marked Sequence Divergence in the Spike Protein of Pipistrellus Bat Coronavirus HKU5 in Japanese Pipistrelle: Implications for the Origin of the Novel Middle East Respiratory Syndrome Coronavirus

(2013) S. K. P. Lau et al.   JOURNAL OF VIROLOGY

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

(2013) R. J. de Groot et al.   JOURNAL OF VIROLOGY

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

(2013) V. Stalin Raj et al.   NATURE

Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

(2012) P. C. Y. Woo et al.   JOURNAL OF VIROLOGY

Interactions of SARS Coronavirus Nucleocapsid Protein with the host cell proteasome subunit p42

(2010) Qin Wang et al.   Virology Journal

Influence of temperature, salinity and E. coli tissue content on immune gene expression in mussel: Results from a 2005–2008 survey

(2009) Hui Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

More and More Coronaviruses: Human Coronavirus HKU1

(2009) Patrick Woo et al.   Viruses-Basel

Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation

(2008) M. Frieman et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS