Mapping the gaps in chemical analysis for the characterisation of aptamer-target interactions

Simultaneous determination of zearalenone and ochratoxin A based on microscale thermophoresis assay with a bifunctional aptamer

(2021) Yan Yang et al.   ANALYTICA CHIMICA ACTA

Designed Alteration of Binding Affinity in Structure-Switching Aptamers through the Use of Dangling Nucleotides

(2020) Sladjana Slavkovic et al.   BIOCHEMISTRY

Finding the Optimal Surface Density of Aptamer Monolayers by SPR Imaging Detection‐Based Aptamer Microarrays

(2020) László Simon et al.   ELECTROANALYSIS

Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as 19F NMR Probes

(2020) Mikolaj Chrominski et al.   JOURNAL OF ORGANIC CHEMISTRY

Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy

(2020) Zhaoying Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Simultaneous detection of streptomycin and kanamycin based on an all-solid-state potentiometric aptasensor array with a dual-internal calibration system

(2020) Juan Yu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair

(2020) Robert J. Trachman et al.   STRUCTURE

Mapping the binding region of aptamer targeting small molecule: Dabigatran etexilate, an anti-coagulant

(2020) Maher M. Aljohani et al.   TALANTA

SERS imaging-based aptasensor for ultrasensitive and reproducible detection of influenza virus A

(2020) Hao Chen et al.   BIOSENSORS & BIOELECTRONICS

5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR

(2020) Marek R Baranowski et al.   NUCLEIC ACIDS RESEARCH

Homogeneous fluorescent aptasensor for active tuberculosis diagnosis by direct quantification of circulating TB7.7 based on aptamer beacon with graphene oxide

(2020) Jinseong Jeon et al.   SENSORS AND ACTUATORS B-CHEMICAL

Selection, characterization, and electrochemical biosensing application of DNA aptamers for sepiapterin

(2020) Shimaa Eissa et al.   TALANTA

Aptamer-Functionalized Drug Nanocarrier Improves Hepatocellular Carcinoma toward Normal by Targeting Neoplastic Hepatocytes

(2020) Samrat Chakraborty et al.   Molecular Therapy-Nucleic Acids

Reduction in Dynamics of Base pair Opening upon Ligand Binding by the Cocaine-Binding Aptamer

(2020) Zachary R. Churcher et al.   BIOPHYSICAL JOURNAL

Identifying conformational changes of aptamer binding to theophylline: A combined biolayer interferometry, surface-enhanced Raman spectroscopy, and molecular dynamics study

(2020) Xiaolin Cui et al.   TALANTA

Directing a rational design of aptamer-based fluorescence anisotropy assay for sensitive detection of immunoglobulin E by site-specific binding study

(2020) Qiang Zhao et al.   TALANTA

Detection of chloramphenicol with an aptamer-based colorimetric assay: critical evaluation of specific and unspecific binding of analyte molecules

(2020) Xiaoqi Tao et al.   Microchimica Acta

Modification performance and electrochemical characteristics of different groups of modified aptamers applied for label-free electrochemical impedimetric sensors

(2020) Mi-Na Nan et al.   FOOD CHEMISTRY

Aptamer-ligand recognition studied by native ion mobility-mass spectrometry

(2020) Elise Daems et al.   TALANTA

GO-amplified fluorescence polarization assay for high-sensitivity detection of aflatoxin B1 with low dosage aptamer probe

(2019) Hua Ye et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Aptamers as quality control tool for production, storage and biosimilarity of the anti-CD20 biopharmaceutical rituximab

(2019) Sabrina Wildner et al.   Scientific Reports

AFFINImeter: A software to analyze molecular recognition processes from experimental data

(2019) Ángel Piñeiro et al.   ANALYTICAL BIOCHEMISTRY

Updates on Aptamer Research

(2019) Ali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amperometric aptasensor for carcinoembryonic antigen based on the use of bifunctionalized Janus nanoparticles as biorecognition-signaling element

(2019) Gonzalo Paniagua et al.   ANALYTICA CHIMICA ACTA

The Arsenic Binding Aptamer Cannot Bind Arsenic: Critical Evaluation of Aptamer Selection and Binding

(2019) Chenghua Zong et al.   ANALYTICAL CHEMISTRY

Target capturing performance of microfluidic channel surface immobilized aptamers: the effects of spacer lengths

(2019) Yubo Qin et al.   BIOMEDICAL MICRODEVICES

Simple and rapid detection of bisphenol A using a gold nanoparticle-based colorimetric aptasensor

(2019) Eun-Hee Lee et al.   FOOD CHEMISTRY

Investigating the properties of TBA variants with twin thrombin binding domains

(2019) Teresa Amato et al.   Scientific Reports

Four steps for revealing and adjusting the 3D structure of aptamers in solution by small-angle X-ray scattering and computer simulation

(2019) Felix N. Tomilin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Fiber optic surface plasmon resonance biosensor for detection of PDGF-BB in serum based on self-assembled aptamer and antifouling peptide monolayer

(2019) Husun Qian et al.   BIOSENSORS & BIOELECTRONICS

Rapid and label-free detection of Brucella melitensis in milk and milk products using an aptasensor

(2019) Gulay Bayramoglu et al.   TALANTA

Evaluation of the binding of natural products with thrombin binding aptamer G-quadruplex using electrospray ionization mass spectrometry and spectroscopic methods

(2019) Pengfei Yang et al.   TALANTA

A novel label-free electrochemical impedance aptasensor for highly sensitive detection of human interferon-gamma based on target-induced exonuclease inhibition

(2019) Huan Li et al.   BIOSENSORS & BIOELECTRONICS

Conformational flexibility of adenine riboswitch aptamer in apo and bound states using NMR and an X-ray free electron laser

(2019) Jienv Ding et al.   JOURNAL OF BIOMOLECULAR NMR

Inside the Black Box: What Makes SELEX Better?

(2019) Natalia Komarova et al.   MOLECULES

Structure of an RNA aptamer in complex with the fluorophore tetramethylrhodamine

(2019) Elke Duchardt-Ferner et al.   NUCLEIC ACIDS RESEARCH

Interaction between thrombin and oligonucleotide RA36 is a two-stage process

(2019) Olga M. Antipova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular characterization of a ghrelin-l-aptamer complex

(2019) Christina Schmidt et al.   JOURNAL OF MOLECULAR STRUCTURE

An Anti-BCMA RNA Aptamer for miRNA Intracellular Delivery

(2019) Silvia Catuogno et al.   Molecular Therapy-Nucleic Acids

Development of a thermal-stable structure-switching cocaine-binding aptamer

(2018) Aron A. Shoara et al.   BIOCHIMIE

Aptamer selection and application in multivalent binding-based electrical impedance detection of inactivated H1N1 virus

(2018) Chenjun Bai et al.   BIOSENSORS & BIOELECTRONICS

Development of a SPR aptasensor containing oriented aptamer for direct capture and detection of tetracycline in multiple honey samples

(2018) Sai Wang et al.   BIOSENSORS & BIOELECTRONICS

Native Electrospray Ionization Mass Spectrometry Reveals Multiple Facets of Aptamer–Ligand Interactions: From Mechanism to Binding Constants

(2018) Basri Gülbakan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plasmonic DNA hotspots made from tungsten disulfide nanosheets and gold nanoparticles for ultrasensitive aptamer-based SERS detection of myoglobin

(2018) Munish Shorie et al.   MICROCHIMICA ACTA

The first successful observation of in-cell NMR signals of DNA and RNA in living human cells

(2018) Yudai Yamaoki et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Selection of acrylamide-specific aptamers by a quartz crystal microbalance combined SELEX method and their application in rapid and specific detection of acrylamide

(2018) Qinqin Hu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Direct fluorescence anisotropy approach for aflatoxin B1 detection and affinity binding study by using single tetramethylrhodamine labeled aptamer

(2018) Linlin Sun et al.   TALANTA

Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry

(2018) Justin M. Di Trani et al.   Nature Communications

Elimination terminal fixed region screening and high-throughput kinetic determination of aptamer for lipocalin-1 by surface plasmon resonance imaging

(2018) Wenchao Jia et al.   ANALYTICA CHIMICA ACTA

Probing ATP/ATP-Aptamer or ATP-Aptamer Mutant Complexes by Microscale Thermophoresis and Molecular Dynamics Simulations: Discovery of an ATP-Aptamer Sequence of Superior Binding Properties

(2018) Yonatan Biniuri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Thermal Denaturation of DNA G-Quadruplexes and Their Complexes with Ligands: Thermodynamic Analysis of the Multiple States Revealed by Mass Spectrometry

(2018) Adrien Marchand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization

(2018) Lars Verdonck et al.   NUCLEIC ACIDS RESEARCH

Nucleic acid aptamers improving fluorescence anisotropy and fluorescence polarization assays for small molecules

(2018) Qiang Zhao et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Real-time crystallographic studies of the adenine riboswitch using an X-ray free-electron laser

(2017) Jason R. Stagno et al.   FEBS Journal

Comparison of the free and ligand-bound imino hydrogen exchange rates for the cocaine-binding aptamer

(2017) Zachary R. Churcher et al.   JOURNAL OF BIOMOLECULAR NMR

Aptamer based surface plasmon resonance sensor for aflatoxin B1

(2017) Linlin Sun et al.   MICROCHIMICA ACTA

Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy

(2017) Hong-Liang Bao et al.   NUCLEIC ACIDS RESEARCH

New insights into a classic aptamer: binding sites, cooperativity and more sensitive adenosine detection

(2017) Zijie Zhang et al.   NUCLEIC ACIDS RESEARCH

A biolayer interferometry-based competitive biosensor for rapid and sensitive detection of saxitoxin

(2017) Shunxiang Gao et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ultrasensitive detection of mucin 1 biomarker by immuno-loop-mediated isothermal amplification

(2017) Hongmei Cao et al.   TALANTA

Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa

(2017) David A. Donkor et al.   Scientific Reports

Compaction of Duplex Nucleic Acids upon Native Electrospray Mass Spectrometry

(2017) Massimiliano Porrini et al.   ACS Central Science

Optimizing Stem Length To Improve Ligand Selectivity in a Structure-Switching Cocaine-Binding Aptamer

(2017) Miguel A. D. Neves et al.   ACS Sensors

An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs

(2017) Gregory R. Wiedman et al.   mSphere

Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker

(2017) Hirotaka Minagawa et al.   Scientific Reports

Real-time electrochemical LAMP: a rational comparative study of different DNA intercalating and non-intercalating redox probes

(2016) Alexandra Martin et al.   ANALYST

Aptamers in analytics

(2016) Muslum Ilgu et al.   ANALYST

Multianalytical Study of the Binding between a Small Chiral Molecule and a DNA Aptamer: Evidence for Asymmetric Steric Effect upon 3′- versus 5′-End Sequence Modification

(2016) Lylian Challier et al.   ANALYTICAL CHEMISTRY

Electrochemical aptamer-based biosensors as potential tools for clinical diagnostics

(2016) Marta Jarczewska et al.   Analytical Methods

Kinetic and Thermodynamic Analyses of Interaction between a High-Affinity RNA Aptamer and Its Target Protein

(2016) Ryo Amano et al.   BIOCHEMISTRY

Aptamer selection by direct microfluidic recovery and surface plasmon resonance evaluation

(2016) Eric Dausse et al.   BIOSENSORS & BIOELECTRONICS

Embracing proteins: structural themes in aptamer–protein complexes

(2016) Amy D Gelinas et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Evaluation of Staphylococcus aureus DNA aptamer by enzyme-linked aptamer assay and isothermal titration calorimetry

(2016) Ceren Bayraç et al.   JOURNAL OF MOLECULAR RECOGNITION

Aptamer-Based K+ Sensor: Process of Aptamer Transforming into G-Quadruplex

(2016) Dongju Zhang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structure and target interaction of a G-quadruplex RNA-aptamer

(2016) Kristina Szameit et al.   RNA Biology

Affinity of aptamers binding 33-mer gliadin peptide and gluten proteins: Influence of immobilization and labeling tags

(2015) Sonia Amaya-González et al.   ANALYTICA CHIMICA ACTA

β-Conglutin dual aptamers binding distinct aptatopes

(2015) Miriam Jauset Rubio et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comprehensive Analytical Comparison of Strategies Used for Small Molecule Aptamer Evaluation

(2015) Maureen McKeague et al.   ANALYTICAL CHEMISTRY

Structure–affinity relationship of the cocaine-binding aptamer with quinine derivatives

(2015) Sladjana Slavkovic et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Replacing antibodies with aptamers in lateral flow immunoassay

(2015) Ailiang Chen et al.   BIOSENSORS & BIOELECTRONICS

Revisiting the streptavidin-biotin binding by using an aptamer and displacement isothermal calorimetry titration

(2015) Tai-Chih Kuo et al.   JOURNAL OF MOLECULAR RECOGNITION

The emerging role of native mass spectrometry in characterizing the structure and dynamics of macromolecular complexes

(2015) Elisabetta Boeri Erba et al.   PROTEIN SCIENCE

RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity

(2015) Florian Mittelberger et al.   RNA Biology

A Label-Free Aptamer-Fluorophore Assembly for Rapid and Specific Detection of Cocaine in Biofluids

(2014) Daniel Roncancio et al.   ANALYTICAL CHEMISTRY

Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform

(2014) Andrew L. Chang et al.   ANALYTICAL CHEMISTRY

Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA

(2014) Dieter Buyst et al.   NUCLEIC ACIDS RESEARCH

Quinine Binding by the Cocaine-Binding Aptamer. Thermodynamic and Hydrodynamic Analysis of High-Affinity Binding of an Off-Target Ligand

(2013) Oren Reinstein et al.   BIOCHEMISTRY

Development of an electrochemical method for Ochratoxin A detection based on aptamer and loop-mediated isothermal amplification

(2013) Shunbi Xie et al.   BIOSENSORS & BIOELECTRONICS

Module-Activity Relationship of G-quadruplex Based DNA Aptamers for Human Thrombin

(2013) E. Zavyalova et al.   CURRENT MEDICINAL CHEMISTRY

Kinetic Rotating Droplet Electrochemistry: A Simple and Versatile Method for Reaction Progress Kinetic Analysis in Microliter Volumes

(2013) Lylian Challier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mass Amplifying Probe for Sensitive Fluorescence Anisotropy Detection of Small Molecules in Complex Biological Samples

(2012) Liang Cui et al.   ANALYTICAL CHEMISTRY

RNA Aptamer-Based Electrochemical Biosensor for Selective and Label-Free Analysis of Dopamine

(2012) Elaheh Farjami et al.   ANALYTICAL CHEMISTRY

Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches

(2012) Vincent J. B. Ruigrok et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Conformational Changes in DNA upon Ligand Binding Monitored by Circular Dichroism

(2012) Yu-Ming Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immobilization-free screening of aptamers assisted by graphene oxide

(2011) Jee-Woong Park et al.   CHEMICAL COMMUNICATIONS

Fluorescence Anisotropy Analysis for Mapping Aptamer–Protein Interaction at the Single Nucleotide Level

(2011) Dapeng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

kinITC: A New Method for Obtaining Joint Thermodynamic and Kinetic Data by Isothermal Titration Calorimetry

(2011) Dominique Burnouf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Optical Detection of Aptamer Conformational Changes Induced by Target Molecules

(2009) Oara Neumann et al.   ANALYTICAL CHEMISTRY

Effect of Linker Structure on Surface Density of Aptamer Monolayers and Their Corresponding Protein Binding Efficiency

(2008) Subramanian Balamurugan et al.   ANALYTICAL CHEMISTRY

Isothermal titration calorimetry at very low c

(2007) Joel Tellinghuisen   ANALYTICAL BIOCHEMISTRY