Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model
出版年份 2021 全文链接
标题
Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model
作者
关键词
Cardiotoxicity, Mitochondria dynamics, Doxorubicin, Mitoxantrone, Aging
出版物
TOXICOLOGY
Volume 459, Issue -, Pages 152852
出版商
Elsevier BV
发表日期
2021-07-09
DOI
10.1016/j.tox.2021.152852
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway
- (2021) Wen-Pin Huang et al. Scientific Reports
- Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice
- (2021) Ana Reis-Mendes et al. Pharmaceuticals
- MiR-526b-3p mediates doxorubicin-induced cardiotoxicity by targeting STAT3 to inactivate VEGFA
- (2020) Lifu Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations
- (2020) Vera Marisa Costa et al. ARCHIVES OF TOXICOLOGY
- Effect of standard low-dose anthracycline chemotherapy on late congestive heart failure in breast cancer survivors aged between 50 and 59 at diagnosis: A nationwide study
- (2020) Il Yong Chung et al. BREAST
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle–Specific Ubiquitin Ligase MuRF1
- (2019) Monte S. Willis et al. Circulation-Heart Failure
- Expression Profiling of Human Pluripotent Stem Cell-Derived Cardiomyocytes Exposed to Doxorubicin—Integration and Visualization of Multi-Omics Data
- (2018) Gustav Holmgren et al. TOXICOLOGICAL SCIENCES
- Influence of PARP-1 inhibition in the cardiotoxicity of the topoisomerase 2 inhibitors doxorubicin and mitoxantrone
- (2018) Roberto Marques Damiani et al. TOXICOLOGY IN VITRO
- Exercise Training Impacts Cardiac Mitochondrial Proteome Remodeling in Murine Urothelial Carcinoma
- (2018) Rita Ferreira et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice
- (2018) Zhi-Meng Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Spinochrome D Attenuates Doxorubicin-Induced Cardiomyocyte Death via Improving Glutathione Metabolism and Attenuating Oxidative Stress
- (2018) Chang Yoon et al. Marine Drugs
- Exploring the Role of Autophagy-Related Gene 5 (ATG5) Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases
- (2018) Xin Ye et al. Frontiers in Immunology
- Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy
- (2017) Sahoko Ichihara et al. Scientific Reports
- Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue
- (2017) Kerstin Boengler et al. Journal of Cachexia Sarcopenia and Muscle
- Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect
- (2017) Tia R. Tidwell et al. Aging and Disease
- Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic ProfilesNovelty and Significance
- (2016) Srinivas Ayyadevara et al. HYPERTENSION
- Men and mice: Relating their ages
- (2016) Sulagna Dutta et al. LIFE SCIENCES
- Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial function
- (2016) Gonçalo C. Pereira et al. MITOCHONDRION
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Drug-induced mitochondrial dysfunction and cardiotoxicity
- (2015) Zoltán V Varga et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The Role of the Metabolism of Anticancer Drugs in Their Induced-Cardiotoxicity
- (2015) Ana Filipa Reis-Mendes et al. CURRENT DRUG METABOLISM
- SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore
- (2015) Santhanam Shanmughapriya et al. MOLECULAR CELL
- Unknown
- (2015) Enkui Hao et al. MOLECULAR MEDICINE
- MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
- (2015) Sarah E. Calvo et al. NUCLEIC ACIDS RESEARCH
- Detailed Analysis of the Human Mitochondrial Contact Site Complex Indicate a Hierarchy of Subunits
- (2015) Christine Ott et al. PLoS One
- Proteomic analysis and functional characterization of mouse brain mitochondria during aging reveal alterations in energy metabolism
- (2015) Kelly L. Stauch et al. PROTEOMICS
- The age factor for mitoxantrone’s cardiotoxicity: Multiple doses render the adult mouse heart more susceptible to injury
- (2015) José Luís Dores-Sousa et al. TOXICOLOGY
- FactoMineR: AnRPackage for Multivariate Analysis
- (2015) Sébastien Lê et al. Journal of Statistical Software
- Mitochondrial Topoisomerase I (Top1mt) Is a Novel Limiting Factor of Doxorubicin Cardiotoxicity
- (2014) S. Khiati et al. CLINICAL CANCER RESEARCH
- Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment
- (2014) Y. Zhao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation
- (2014) Yoshihiko Ichikawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Lifelong Exercise Training Modulates Cardiac Mitochondrial Phosphoproteome in Rats
- (2014) Rita Ferreira et al. JOURNAL OF PROTEOME RESEARCH
- Metabolomics Data Normalization with EigenMS
- (2014) Yuliya V. Karpievitch et al. PLoS One
- Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
- (2014) Chancievan Thangaratnarajah et al. Nature Communications
- Mitochondrial Cumulative Damage Induced by Mitoxantrone: Late Onset Cardiac Energetic Impairment
- (2013) Luciana Grazziotin Rossato et al. Cardiovascular Toxicology
- Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event
- (2013) Luciana Grazziotin Rossato et al. Cardiovascular Toxicology
- Citric Acid Cycle and Role of its Intermediates in Metabolism
- (2013) Muhammad Akram CELL BIOCHEMISTRY AND BIOPHYSICS
- Cardiac Metabolism in Heart Failure
- (2013) Torsten Doenst et al. CIRCULATION RESEARCH
- Topoisomerase 2β: A Promising Molecular Target for Primary Prevention of Anthracycline-Induced Cardiotoxicity
- (2013) P Vejpongsa et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Mass spectrometry-based proteomics: existing capabilities and future directions
- (2012) Thomas E. Angel et al. CHEMICAL SOCIETY REVIEWS
- The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy
- (2012) Yu Lei et al. IMMUNITY
- Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects
- (2012) Steen Larsen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Cardiac phosphoproteome reveals cell signaling events involved in doxorubicin cardiotoxicity
- (2012) Séverine Gratia et al. Journal of Proteomics
- Cardiac angiogenic imbalance leads to peripartum cardiomyopathy
- (2012) Ian S. Patten et al. NATURE
- Identification of the molecular basis of doxorubicin-induced cardiotoxicity
- (2012) Sui Zhang et al. NATURE MEDICINE
- OXPHOS susceptibility to oxidative modifications: The role of heart mitochondrial subcellular location
- (2011) Ana Isabel Padrão et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity
- (2011) Lei Xi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte
- (2011) Suresh N. Kumar et al. Journal of Proteomics
- MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization
- (2011) Alwaleed K. Alkhaja et al. MOLECULAR BIOLOGY OF THE CELL
- MISC-1/OGC Links Mitochondrial Metabolism, Apoptosis and Insulin Secretion
- (2011) Marco Gallo et al. PLoS One
- Mitochondria and the aging heart
- (2011) Chaudhary Ketul R et al. Journal of Geriatric Cardiology
- Role of heat shock factor-1 activation in the doxorubicin-induced heart failure in mice
- (2010) Kaushik Vedam et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
- (2010) Richard C. Scarpulla BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV
- (2010) Qian Han et al. BIOSCIENCE REPORTS
- Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice
- (2010) Chengqun Huang et al. CIRCULATION
- Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
- (2010) Graham M. Strub et al. FASEB JOURNAL
- Measuring adriamycin-induced cardiac hemodynamic dysfunction with a proteomics approach
- (2010) Yan Cui et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Enzymology of the branched-chain amino acid oxidation disorders: the valine pathway
- (2010) Ronald J. A. Wanders et al. JOURNAL OF INHERITED METABOLIC DISEASE
- The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results
- (2010) Ronald J. A. Wanders et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy
- (2010) Rui A. Carvalho et al. TOXICOLOGY
- Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle
- (2009) Vladimir Ljubicic et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs
- (2008) Neil Ashley et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles
- (2008) S. Hiller et al. SCIENCE
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started