Topoisomerase 2β: A Promising Molecular Target for Primary Prevention of Anthracycline-Induced Cardiotoxicity

Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits

(2013) Eduard Jirkovský et al.   TOXICOLOGY

Cardiac angiogenic imbalance leads to peripartum cardiomyopathy

(2012) Ian S. Patten et al.   NATURE

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α

(2012) Wenjun Song et al.   NEUROBIOLOGY OF DISEASE

The low incidence of secondary acute myelogenous leukaemia in children and adolescents treated with dexrazoxane for acute lymphoblastic leukaemia: A report from the Dana-Farber Cancer Institute ALL Consortium

(2011) Lynda M. Vrooman et al.   EUROPEAN JOURNAL OF CANCER

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts

(2009) Vilma A. Sardão et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cardiovascular Complications of Cancer Therapy

(2009) Edward T.H. Yeh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984–2001: a report from the children's oncology group

(2009) W L Salzer et al.   LEUKEMIA

Acute leukemia as a secondary malignancy in children and adolescents: Current findings and issues

(2008) Nobuko Hijiya et al.   CANCER

Acute Doxorubicin Cardiotoxicity Is Associated With p53-Induced Inhibition of the Mammalian Target of Rapamycin Pathway

(2008) Wuqiang Zhu et al.   CIRCULATION

NK314, a Topoisomerase II Inhibitor That Specifically Targets the α Isoform

(2008) Eriko Toyoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

American Society of Clinical Oncology 2008 Clinical Practice Guideline Update: Use of Chemotherapy and Radiation Therapy Protectants

(2008) Martee L. Hensley et al.   JOURNAL OF CLINICAL ONCOLOGY

PGC-1α and ERRα target gene downregulation is a signature of the failing human heart

(2008) Smita Sihag et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY