An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Proteomic and Metabolomic Characterization of COVID-19 Patient Sera

(2020) Bo Shen et al.   CELL

HLA‐DQ genotype and biochemical characterization of anti‐transglutaminase 2 antibodies in patients with type 1 diabetes mellitus in Taiwan

(2020) Yann‐Jinn Lee et al.   FASEB JOURNAL

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

(2020) Denisa Bojkova et al.   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19

(2020) Louise Bowles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease

(2020) Brendan T Freitas et al.   ACS Infectious Diseases

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

(2020) He-wei Jiang et al.   Cellular & Molecular Immunology

Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication

(2020) Kevin Klann et al.   MOLECULAR CELL

Clinical features of LRP4 /agrin‐antibody–positive myasthenia gravis: A multicenter study

(2020) Michael H. Rivner et al.   MUSCLE & NERVE

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

(2020) Laura Riva et al.   NATURE

Single-cell landscape of immunological responses in patients with COVID-19

(2020) Ji-Yuan Zhang et al.   NATURE IMMUNOLOGY

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

(2020) Conor N. Gruber et al.   CELL

High levels of anti-SSA/Ro antibodies in COVID-19 patients with severe respiratory failure: a case-based review

(2020) Hiroyuki Fujii et al.   CLINICAL RHEUMATOLOGY

Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia

(2020) Lara Gibellini et al.   EMBO Molecular Medicine

Myelin Oligodendrocyte Glycoprotein Antibody–Associated Optic Neuritis and Myelitis in COVID-19

(2020) Siwei Zhou et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age

(2020) Nicole A. P. Lieberman et al.   PLOS BIOLOGY

A proteomic repertoire of autoantigens identified from the classic autoantibody clinical test substrate HEp-2 cells

(2020) Julia Y. Wang et al.   Clinical Proteomics

Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

(2020) Daniel Gagiannis et al.   Frontiers in Immunology

Comparative Transcriptome Analysis Reveals the Intensive Early Stage Responses of Host Cells to SARS-CoV-2 Infection

(2020) Jiya Sun et al.   Frontiers in Microbiology

Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies

(2020) Jonathan P. Davies et al.   ACS Infectious Diseases

Autoantibody Formation and Mapping of Immunogenic Epitopes against Cold-Shock-Protein YB-1 in Cancer Patients and Healthy Controls

(2020) Ronnie Morgenroth et al.   Cancers

A comprehensive autoantigen-ome of autoimmune liver diseases identified from dermatan sulfate affinity enrichment of liver tissue proteins

(2019) Wei Zhang et al.   BMC IMMUNOLOGY

Autoantibody-targeted TAAs in pancreatic cancer: A comprehensive analysis

(2019) Yabin Zhou et al.   PANCREATOLOGY

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Serum anti-EIF3A autoantibody as a potential diagnostic marker for hepatocellular carcinoma

(2019) Chang-Kyu Heo et al.   Scientific Reports

ShinyGO: a graphical gene-set enrichment tool for animals and plants

(2019) Steven Xijin Ge et al.   BIOINFORMATICS

Evaluation of a panel of tumor-associated antigens in breast cancer

(2019) Cecilia Pagaza-Straffon et al.   Cancer Biomarkers

Identification of novel non-myelin biomarkers in multiple sclerosis using an improved phage-display approach

(2019) Andrea Cortini et al.   PLoS One

Anti-tubulin-α-1C autoantibody in systemic lupus erythematosus: a novel indicator of disease activity and vasculitis manifestations

(2018) Xiaozhen Zhao et al.   CLINICAL RHEUMATOLOGY

Autoantibody against aldehyde dehydrogenase 2 could be a biomarker to monitor progression of Graves’ orbitopathy

(2018) Kai-Chun Cheng et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Antibodies against H3 and H4 histones from the sera of HIV-infected patients catalyze site-specific degradation of these histones

(2018) Svetlana V. Baranova et al.   JOURNAL OF MOLECULAR RECOGNITION

Immunoproteomic identification of antigenic candidate Campylobacter jejuni and human peripheral nerve proteins involved in Guillain-Barré syndrome

(2018) Aida Loshaj-Shala et al.   JOURNAL OF NEUROIMMUNOLOGY

Identification of anti-SF3B1 autoantibody as a diagnostic marker in patients with hepatocellular carcinoma

(2018) Hai-Min Hwang et al.   Journal of Translational Medicine

Monodisperse magnetic poly(glycidyl methacrylate) microspheres for isolation of autoantibodies with affinity for the 46 kDa form of unconventional Myo1C present in autoimmune patients

(2018) Beata A. Zasońska et al.   MICROCHIMICA ACTA

Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library

(2018) Sohei Kobayashi et al.   Oncotarget

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

(2018) Hanna D. Bremer et al.   Scientific Reports

Development of a New Classification System for Idiopathic Inflammatory Myopathies Based on Clinical Manifestations and Myositis-Specific Autoantibodies

(2018) Kubéraka Mariampillai et al.   JAMA Neurology

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Autoantibodies Against Albumin in Patients With Systemic Lupus Erythematosus

(2018) Josephine Nehring et al.   Frontiers in Immunology

Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line

(2017) Abdullah Almamy et al.   IMMUNOLOGIC RESEARCH

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice

(2017) Bharathi Krishnan et al.   JOURNAL OF IMMUNOLOGY

Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis

(2017) Fu Jun Li et al.   JOURNAL OF IMMUNOLOGY

Identification of novel autoantigens via mass spectroscopy-based antibody-mediated identification of autoantigens (MS-AMIDA) using immune thrombocytopenic purpura (ITP) as a model disease

(2017) Julian Kamhieh-Milz et al.   Journal of Proteomics

Antibodies to H2a and H2b histones from the sera of HIV-infected patients catalyze site-specific degradation of these histones

(2017) Svetlana V. Baranova et al.   Molecular BioSystems

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

(2017) Fumitaka Shimizu et al.   Science Translational Medicine

Serum proteomic-based analysis identifying autoantibodies against PRDX2 and PRDX3 as potential diagnostic biomarkers in nasopharyngeal carcinoma

(2017) Lie-Hao Lin et al.   Clinical Proteomics

Identification of autoantibodies to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer

(2017) Liping Dai et al.   OncoImmunology

Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis

(2016) Maximilian F Konig et al.   ANNALS OF THE RHEUMATIC DISEASES

Use of the VH6-1 gene segment to code for anti-interleukin-18 autoantibodies in multiple sclerosis

(2016) Marina Tiumentseva et al.   IMMUNOGENETICS

Copa Syndrome: a Novel Autosomal Dominant Immune Dysregulatory Disease

(2016) Timothy J. Vece et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Protein disulfide isomerase A3–specific Th1 effector cells infiltrate colon cancer tissue of patients with circulating anti–protein disulfide isomerase A3 autoantibodies

(2016) Cristiana Caorsi et al.   Translational Research

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

(2016) S. Karniely et al.   mBio

Anti-GAPDH Autoantibodies as a Pathogenic Determinant and Potential Biomarker of Neuropsychiatric Diseases

(2016) Federica Delunardo et al.   Arthritis & Rheumatology

The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 α1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults

(2016) Eunhee G. Kim et al.   Diabetes & Metabolism Journal

Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency

(2015) Atsushi Kiyota et al.   ENDOCRINE JOURNAL

Novel serum autoantibodies against talin1 in multiple sclerosis: Possible pathogenetic roles of the antibodies

(2015) Mayumi Muto et al.   JOURNAL OF NEUROIMMUNOLOGY

‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr/DNER, other antibodies, diagnostic pitfalls, summary and outlook

(2015) S. Jarius et al.   Journal of Neuroinflammation

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

(2015) Levi B Watkin et al.   NATURE GENETICS

Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis

(2015) Dawn J. Caster et al.   Proteomics Clinical Applications

Detection of red blood cell antibodies in mitogen-stimulated cultures from patients with hereditary spherocytosis

(2015) Anna Zaninoni et al.   TRANSFUSION

Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis

(2015) Alessandro Iannaccone et al.   PLoS One

Circulating anti-filamin C autoantibody as a potential serum biomarker for low-grade gliomas

(2014) Masayo Adachi-Hayama et al.   BMC CANCER

Detection of novel auto-antigens in patients with recurrent miscarriage: description of an approach and preliminary findings

(2014) Yuriy Kit et al.   CROATIAN MEDICAL JOURNAL

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

(2014) Chong-Shan Shi et al.   JOURNAL OF IMMUNOLOGY

Glomerular Autoimmune Multicomponents of Human Lupus Nephritis In Vivo (2): Planted Antigens

(2014) M. Bruschi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus

(2014) Y. M. Baez-Santos et al.   JOURNAL OF VIROLOGY

Antibody against chromatin assembly factor-1 is a novel autoantibody specifically recognized in systemic lupus erythematosus

(2014) K Doe et al.   LUPUS

Proteomic identification of heterogeneous nuclear ribonucleoprotein K as a novel cold-associated autoantigen in patients with secondary Raynaud’s phenomenon

(2014) Lingli Yang et al.   RHEUMATOLOGY

Identification of Citrullinated Hsp90 Isoforms as Novel Autoantigens in Rheumatoid Arthritis-Associated Interstitial Lung Disease

(2013) Lisa Harlow et al.   ARTHRITIS AND RHEUMATISM

Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models

(2013) Michela Capello et al.   Journal of Hematology & Oncology

Serological Proteome Analysis (SERPA) as a tool for the identification of new candidate autoantigens in type 1 diabetes

(2013) Ornella Massa et al.   Journal of Proteomics

A novel autoantibody against moesin in the serum of patients with MPO-ANCA-associated vasculitis

(2013) Koya Suzuki et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Myasthenia Gravis: Analysis of Serum Autoantibody Reactivities to 1827 Potential Human Autoantigens by Protein Macroarrays

(2013) Anne Becker et al.   PLoS One

Anti-human protein S antibody induces tissue factor expression through a direct interaction with platelet phosphofructokinase

(2013) Changyi Chen et al.   THROMBOSIS RESEARCH

Autoantibodies to RuvBL1 and RuvBL2: A Novel Systemic Sclerosis-Related Antibody Associated With Diffuse Cutaneous and Skeletal Muscle Involvement

(2013) Kenzou Kaji et al.   ARTHRITIS CARE & RESEARCH

Serum antibody response to group II chaperonin fromMethanobrevibacter oralisand human chaperonin CCT

(2013) Kimito Hirai et al.   Pathogens and Disease

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

(2013) D Braunschweig et al.   Translational Psychiatry

Alterations in Antibody Subclass Immune Reactivity to Trophoblast-derived Fetal Fibronectin and α2-Macroglobulin in Women with Recurrent Pregnancy Loss

(2012) Rhiana D. Saunders et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin

(2012) Joyce J. B. C. van Beers et al.   ARTHRITIS AND RHEUMATISM

Identification of autoantibodies expressed in acquired aplastic anaemia

(2012) Maki Goto et al.   BRITISH JOURNAL OF HAEMATOLOGY

Anti-Endothelial Cell Antibodies in Patients with Cerebral Small Vessel Disease

(2012) Akio Kimura et al.   CURRENT NEUROVASCULAR RESEARCH

High Prevalence of Autoantibodies to hLAMP-2 in Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

(2012) R. Kain et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nodal proteins are target antigens in Guillain-Barré syndrome

(2012) Jérôme J. Devaux et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders

(2012) Daniela Privitera et al.   NEUROLOGICAL SCIENCES

Human Proteins with Affinity for Dermatan Sulfate Have the Propensity to Become Autoantigens

(2011) Jung-hyun Rho et al.   AMERICAN JOURNAL OF PATHOLOGY

Dermatan Sulfate Interacts with Dead Cells and Regulates CD5+ B-Cell Fate

(2011) Julia Y. Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Autoantibodies to survival of motor neuron complex in patients with polymyositis: Immunoprecipitation of D, E, F, and G proteins without other components of small nuclear ribonucleoproteins

(2011) Minoru Satoh et al.   ARTHRITIS AND RHEUMATISM

Heterogeneous nuclear RNPs as targets of autoantibodies in systemic rheumatic diseases

(2011) Katrijn Op De Beéck et al.   ARTHRITIS AND RHEUMATISM

Identification and validation of novel serum markers for early diagnosis of endometriosis

(2011) R. Gajbhiye et al.   HUMAN REPRODUCTION

Autoimmunity to endoplasmic reticulum chaperone GRP94 in myasthenia gravis

(2011) Shigeaki Suzuki et al.   JOURNAL OF NEUROIMMUNOLOGY

Identification of Three New Autoantibodies Associated with Systemic Lupus Erythematosus Using Two Proteomic Approaches

(2011) Yasuhiro Katsumata et al.   MOLECULAR & CELLULAR PROTEOMICS

Auto-Antibodies to β-F1-ATPase and Vimentin in Malignant Mesothelioma

(2011) Jenette Creaney et al.   PLoS One

Identification and validation of candidate biomarkers involved in human ovarian autoimmunity

(2011) Purvi V. Mande et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Annexin A5 and anti-annexin antibodies in patients with systemic lupus erythematosus

(2011) Antoni Hrycek et al.   RHEUMATOLOGY INTERNATIONAL

Antibodies Against Nucleolin in Recipients of Organ Transplants

(2011) Zhiqiang Qin et al.   TRANSPLANTATION

Autoantibodies against different histone hi subtypes in systemic lupus erythematosus sera

(2010) Jözefa Wesierska-Gadek et al.   ARTHRITIS AND RHEUMATISM

Anti-5S RNA/protein (RNP) antibody levels correlate with disease activity in a patient with systemic lupus erythematosus (SLE) nephritis

(2010) A. GUIALIS et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease

(2010) A. KRATZ et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Non-muscle myosin as target antigen for human autoantibodies in patients with hepatitis C virus-associated chronic liver diseases

(2010) C. A. MÜHLEN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Autoantibodies against eukaryotic protein L7 in patients suffering from systemic lupus erythematosus and progressive systemic sclerosis: frequency and correlation with clinical, serological and genetic parameters

(2010) E. NEU et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Lupus autoantibodies discriminate between the highly homologous Sm polypeptides B/B’ and SmN by binding an epitope restricted to B/B'

(2010) J. D. HUNTRISS et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Glomerular Antibodies in Lupus Nephritis

(2010) Catherine Hanrotel-Saliou et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure

(2010) Seby L. Edassery et al.   FERTILITY AND STERILITY

Seroreactivity against glycolytic enzymes in inflammatory bowel disease

(2010) Nathalie Vermeulen et al.   INFLAMMATORY BOWEL DISEASES

Cleavage of Transaldolase by Granzyme B Causes the Loss of Enzymatic Activity with Retention of Antigenicity for Multiple Sclerosis Patients

(2010) B. Niland et al.   JOURNAL OF IMMUNOLOGY

Autoimmunity in Membranous Nephropathy Targets Aldose Reductase and SOD2

(2010) M. Prunotto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus

(2010) C. K. Weber et al.   RHEUMATOLOGY

Do we need new autoantibodies in lupus?

(2010) R Hal Scofield   ARTHRITIS RESEARCH & THERAPY

Gene Expression Patterns of Dengue Virus-Infected Children from Nicaragua Reveal a Distinct Signature of Increased Metabolism

(2010) P'ng Loke et al.   PLoS Neglected Tropical Diseases

Identification of a New Panel of Serum Autoantibodies Associated with the Presence of In situ Carcinoma of the Breast in Younger Women

(2009) C. Desmetz et al.   CLINICAL CANCER RESEARCH

Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies

(2009) Casandra C. van Bavel et al.   MOLECULAR IMMUNOLOGY

Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis

(2009) Jianjun Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Identification of Target Antigens of Antifibroblast Antibodies in Pulmonary Arterial Hypertension

(2008) Benjamin Terrier et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clinical and human leucocyte antigen class II haplotype associations of autoantibodies to small ubiquitin-like modifier enzyme, a dermatomyositis-specific autoantigen target, in UK Caucasian adult-onset myositis

(2008) Z E Betteridge et al.   ANNALS OF THE RHEUMATIC DISEASES

Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K

(2008) J Dieker et al.   CELL DEATH AND DIFFERENTIATION

Biological autoimmunity screening in hepatitis C patients by anti-HepG2 lysate and anti-heat shock protein 70.1 autoantibodies

(2008) B. F. F. Chumpitazi et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Occurrence of Autoantibodies to Annexin I, 14-3-3 Theta and LAMR1 in Prediagnostic Lung Cancer Sera

(2008) Ji Qiu et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of L-plastin autoantibody in plasma of patients with non-Hodgkin's lymphoma using a proteomics-based analysis

(2008) Kazuhito Ueda et al.   ANNALS OF CLINICAL BIOCHEMISTRY