Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica

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Isthmin is a novel vascular permeability inducer that functions through cell-surface GRP78-mediated Src activation

(2015) Shruthi Venugopal et al.   CARDIOVASCULAR RESEARCH

The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations

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A Novel Three-Dimensional Human Peritubular Microvascular System

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Antibodies as Mediators of Brain Pathology

(2015) Lior Brimberg et al.   TRENDS IN IMMUNOLOGY

GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids

(2014) Anna A. Birukova et al.   MOLECULAR BIOLOGY OF THE CELL

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

(2014) Marios C. Papadopoulos et al.   Nature Reviews Neurology

Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers

(2014) Hélène Jeltsch-David et al.   Nature Reviews Neurology

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(2013) Ryan J Watts et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

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(2013) Sven Jarius et al.   Journal of Neuroinflammation

NMO sera down-regulate AQP4 in human astrocyte and induce cytotoxicity independent of complement

(2013) Hiroyo Haruki et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

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(2013) Birgit Obermeier et al.   NATURE MEDICINE

Developing Therapeutic Antibodies for Neurodegenerative Disease

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Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

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Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly

(2012) Andrea Rossi et al.   GLIA

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

(2012) Yukio Takeshita et al.   IMMUNOLOGICAL REVIEWS

Serologic diagnosis of NMO: A multicenter comparison of aquaporin-4-IgG assays

(2012) P. J. Waters et al.   NEUROLOGY

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

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Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms

(2011) Hua Zhang et al.   ANNALS OF NEUROLOGY

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL

Endothelial ICAM-1 Protein Induction Is Regulated by Cytosolic Phospholipase A2  via Both NF- B and CREB Transcription Factors

(2011) N. Hadad et al.   JOURNAL OF IMMUNOLOGY

Sera from neuromyelitis optica patients disrupt the blood–brain barrier

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Neuromyelitis optica spectrum disorders in patients with myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature

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Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

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Intractable vomiting as the initial presentation of neuromyelitis optica

(2010) Metha Apiwattanakul et al.   ANNALS OF NEUROLOGY

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function

(2010) Yasuteru Sano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

(2010) Sven Jarius et al.   Journal of Neuroinflammation

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Disruption of the blood–brain barrier in collagen-induced arthritic mice

(2010) Tsuyoshi Nishioku et al.   NEUROSCIENCE LETTERS

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid

(2009) Gregory P. Owens et al.   ANNALS OF NEUROLOGY

Neuromyelitis Optica and Non–Organ-Specific Autoimmunity

(2008) Sean J. Pittock et al.   ARCHIVES OF NEUROLOGY