Fenton-Chemistry-Based Oxidative Modification of Proteins Reflects Their Conformation

Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors

(2021) Michael Bauder et al.   JOURNAL OF MEDICINAL CHEMISTRY

Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity

(2021) Andreas M. Voll et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison

(2021) K. Groves et al.   ANALYTICAL CHEMISTRY

Mass Spectrometry-Based Protein Footprinting for Higher-Order Structure Analysis: Fundamentals and Applications

(2020) Xiaoran Roger Liu et al.   CHEMICAL REVIEWS

Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology

(2020) Timothy M. Allison et al.   ANALYTICAL CHEMISTRY

Evaluation of NHS-Acetate and DEPC labelling for determination of solvent accessible amino acid residues in protein complexes

(2020) Marie Barth et al.   Journal of Proteomics

Mass spectrometry: From plasma proteins to mitochondrial membranes

(2019) Carol V. Robinson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gas-Phase Hydrogen/Deuterium Scrambling in Negative-Ion Mode Tandem Mass Spectrometry

(2019) Qingyi Wang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Selective inhibitors of FKBP51 employ conformational selection of dynamic invisible states

(2019) Pravin Kumar Ankush Jagtap et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PepFoot: a software package for semi-automated processing of protein footprinting data

(2019) Jeddidiah Bellamy-Carter et al.   JOURNAL OF PROTEOME RESEARCH

Protein dynamics and conformational changes explored by hydrogen/deuterium exchange mass spectrometry

(2019) Jie Zheng et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Fast photochemical oxidation of proteins(FPOP): A powerful mass spectrometry based structural proteomics tool

(2019) Danté T Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

(2019) Glenn R. Masson et al.   NATURE METHODS

Mapping low-affinity/high-specificity peptide–protein interactions using ligand-footprinting mass spectrometry

(2019) Benjamin W. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mass Spectrometry-Based Fast Photochemical Oxidation of Proteins (FPOP) for Higher Order Structure Characterization

(2018) Ke Sherry Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins

(2018) Sebastian Pomplun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evolution of Structural Biology through the Lens of Mass Spectrometry

(2018) Upneet Kaur et al.   ANALYTICAL CHEMISTRY

Chemical Generation of Hydroxyl Radical for Oxidative Footprinting

(2018) Michael Brenowitz et al.   PROTEIN AND PEPTIDE LETTERS

Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly

(2018) Kelly R. Karch et al.   STRUCTURE

FKBP Ligands—Where We Are and Where to Go?

(2018) Jürgen M. Kolos et al.   Frontiers in Pharmacology

Suppressing allostery in epitope mapping experiments using millisecond hydrogen / deuterium exchange mass spectrometry

(2017) Bin Deng et al.   mAbs

Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment

(2017) Liwen Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry

(2017) Simone Schopper et al.   Nature Protocols

Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability

(2017) Pascal Leuenberger et al.   SCIENCE

Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51

(2016) Steffen Gaali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Probing the Time Scale of FPOP (Fast Photochemical Oxidation of Proteins): Radical Reactions Extend Over Tens of Milliseconds

(2016) Siavash Vahidi et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Native Mass Spectrometry: What is in the Name?

(2016) Aneika C. Leney et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Carbene footprinting accurately maps binding sites in protein–ligand and protein–protein interactions

(2016) Lucio Manzi et al.   Nature Communications

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

Selective inhibitors of the FK506-binding protein 51 by induced fit

(2014) Steffen Gaali et al.   Nature Chemical Biology

A mass spectrometry–based hybrid method for structural modeling of protein complexes

(2014) Argyris Politis et al.   NATURE METHODS

Characterizing rapid, activity-linked conformational transitions in proteins via sub-second hydrogen deuterium exchange mass spectrometry

(2013) Diana Resetca et al.   FEBS Journal

Native ion mobility-mass spectrometry and related methods in structural biology

(2012) A. Konijnenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Pulsed hydrogen/deuterium exchange mass spectrometry for time-resolved membrane protein folding studies

(2012) Anil Khanal et al.   JOURNAL OF MASS SPECTROMETRY

Conformational Dynamics of a Membrane Transport Protein Probed by H/D Exchange and Covalent Labeling: The Glycerol Facilitator

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Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

(2011) Andreas Bracher et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Mass Spectrometry of Proteins Using Hydroxyl Radical Based Protein Footprinting

(2011) Liwen Wang et al.   ANALYTICAL CHEMISTRY

Protein folding mechanisms studied by pulsed oxidative labeling and mass spectrometry

(2011) Lars Konermann et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mass spectrometry: come of age for structural and dynamical biology

(2011) Justin LP Benesch et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Hydrogen Exchange Mass Spectrometry of Bacteriorhodopsin Reveals Light-Induced Changes in the Structural Dynamics of a Biomolecular Machine

(2011) Yan Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Membrane protein structural insights from chemical labeling and mass spectrometry

(2010) Yan Pan et al.   ANALYST

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

Fluorescent Probes to Characterise FK506-Binding Proteins

(2009) Christian Kozany et al.   CHEMBIOCHEM

Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein

(2009) Jingxi Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Elucidatingin VivoStructural Dynamics in Integral Membrane Protein by Hydroxyl Radical Footprinting

(2009) Yi Zhu et al.   MOLECULAR & CELLULAR PROTEOMICS

Electron Transfer Dissociation Facilitates the Measurement of Deuterium Incorporation into Selectively Labeled Peptides with Single Residue Resolution

(2008) Martin Zehl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Footprinting protein–DNA complexes using the hydroxyl radical

(2008) Swapan S Jain et al.   Nature Protocols