MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking

Bridging the gap: virus long distance spread via tunneling nanotubes

(2020) Robert J.J. Jansens et al.   JOURNAL OF VIROLOGY

Miro: A molecular switch at the center of mitochondrial regulation

(2020) Emily L. Eberhardt et al.   PROTEIN SCIENCE

Interpericyte tunnelling nanotubes regulate neurovascular coupling

(2020) Luis Alarcon-Martinez et al.   NATURE

Rab35 and its effectors promote formation of tunneling nanotubes in neuronal cells

(2020) Shaarvari Bhat et al.   Scientific Reports

Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

(2020) Alexander Tishchenko et al.   Cancers

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids

(2020) Giulia Pinto et al.   BIOCHEMICAL JOURNAL

CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma

(2019) Christopher R. Marlein et al.   CANCER RESEARCH

Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells

(2019) Anna Sartori-Rupp et al.   Nature Communications

Rhes travels from cell to cell and transports Huntington disease protein via TNT-like protrusion

(2019) Manish Sharma et al.   JOURNAL OF CELL BIOLOGY

Are cell membrane nanotubes the ancestors of the nervous system?

(2019) H. Moysés Nussenzveig   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Tunneling Nanotubes Mediate the Expression of Senescence Markers in Mesenchymal Stem/Stromal Cell Spheroids

(2019) Jacklyn Whitehead et al.   STEM CELLS

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

(2019) Richard Burt et al.   BLOOD

The Wnt/Ca 2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes

(2019) Jessica Y Vargas et al.   EMBO JOURNAL

MICALs

(2018) Laura Taylor Alto et al.   CURRENT BIOLOGY

Tunneling Nanotubes: A Versatile Target for Cancer Therapy

(2018) Pragyaparamita Sahu et al.   CURRENT CANCER DRUG TARGETS

Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

(2018) Guillermo López‐Doménech et al.   EMBO JOURNAL

Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

(2018) Jiancheng Wang et al.   Journal of Hematology & Oncology

Tunneling Nanotubes as a Novel Route of Cell-to-Cell Spread of Herpesviruses

(2018) Mirosława Panasiuk et al.   JOURNAL OF VIROLOGY

Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer

(2018) Snider Desir et al.   Scientific Reports

Overexpression of MICAL2, a novel tumor-promoting factor, accelerates tumor progression through regulating cell proliferation and EMT

(2018) Yongqiang Cai et al.   Journal of Cancer

Tunneling Nanotubes: Intimate Communication between Myeloid Cells

(2018) Maeva Dupont et al.   Frontiers in Immunology

Specialized Intercellular Communications via Cytonemes and Nanotubes

(2018) Yukiko M. Yamashita et al.   Annual Review of Cell and Developmental Biology

The role of metabolism and tunneling nanotube-mediated intercellular mitochondria exchange in cancer drug resistance

(2018) Yalda Hekmatshoar et al.   BIOCHEMICAL JOURNAL

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX

(2018) Stefanie J. Oeding et al.   JOURNAL OF CELL SCIENCE

Rab11a-Rab8a cascade regulate the formation of tunneling nanotubes through vesicle recycling

(2018) Seng Zhu et al.   JOURNAL OF CELL SCIENCE

FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models

(2018) Jianwen Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oral fluorouracil vs vinorelbine plus cisplatin as adjuvant chemotherapy for stage II-IIIA non-small cell lung cancer: Propensity score-matched and instrumental variable analyses

(2018) Hirokazu Urushiyama et al.   Cancer Medicine

A role for RASSF1A in tunneling nanotube formation between cells through GEFH1/Rab11 pathway control

(2018) Fatéméh Dubois et al.   Cell Communication and Signaling

Mitochondrial dynamics and metastasis

(2018) Dario C. Altieri   CELLULAR AND MOLECULAR LIFE SCIENCES

Macrophage conditioned medium induced cellular network formation in MCF-7 cells through enhanced tunneling nanotube formation and tunneling nanotube mediated release of viable cytoplasmic fragments

(2017) Pooja Patheja et al.   EXPERIMENTAL CELL RESEARCH

Notch Signaling in Development, Tissue Homeostasis, and Disease

(2017) Chris Siebel et al.   PHYSIOLOGICAL REVIEWS

Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells

(2017) Jinjin Lu et al.   Oncotarget

The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

(2017) Samer J. Hanna et al.   Scientific Reports

Gap junction as an intercellular glue: Emerging roles in cancer EMT and metastasis

(2016) Xiao-Yuan Mao et al.   CANCER LETTERS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Exosomes and nanotubes: Control of immune cell communication

(2016) Kessler McCoy-Simandle et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

(2016) Brian Cunniff et al.   MOLECULAR BIOLOGY OF THE CELL

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

(2016) Snider Desir et al.   Oncotarget

The missing link: does tunnelling nanotube-based supercellularity provide a new understanding of chronic and lifestyle diseases?

(2016) Amin Rustom   Open Biology

Tunneling nanotubes mediate rescue of prematurely senescent endothelial cells by endothelial progenitors: exchange of lysosomal pool

(2016) Kaoru Yasuda et al.   Aging-US

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes

(2016) Elise Delage et al.   Scientific Reports

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

(2015) R. Polak et al.   BLOOD

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

(2015) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression

(2015) Ruirui Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

Nanotubes mediate niche–stem-cell signalling in the Drosophila testis

(2015) Mayu Inaba et al.   NATURE

Prion aggregates transfer through tunneling nanotubes in endocytic vesicles

(2015) Seng Zhu et al.   Prion

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

(2015) M. Cecilia Caino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion

(2015) Sara Mariotti et al.   Oncotarget

Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling

(2014) Mark R. Lundquist et al.   CELL

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy

(2014) Tanveer Ahmad et al.   EMBO JOURNAL

CD40L Induces Functional Tunneling Nanotube Networks Exclusively in Dendritic Cells Programmed by Mediators of Type 1 Immunity

(2014) Colleen R. Zaccard et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

(2014) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes

(2014) Justin W. Ady et al.   Frontiers in Physiology

SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

(2013) Ruei-Jiun Hung et al.   NATURE CELL BIOLOGY

Different Modalities of Intercellular Membrane Exchanges Mediate Cell-to-cell P-glycoprotein Transfers in MCF-7 Breast Cancer Cells

(2012) Jennifer Pasquier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential regulation of actin microfilaments by human MICAL proteins

(2012) S. S. P. Giridharan et al.   JOURNAL OF CELL SCIENCE

Tunneling nanotube formation is essential for the regulation of osteoclastogenesis

(2012) Akira Takahashi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes

(2012) Dierk Wittig et al.   PLoS One

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma

(2012) Emil Lou et al.   PLoS One

Developing Neurons Form Transient Nanotubes Facilitating Electrical Coupling and Calcium Signaling with Distant Astrocytes

(2012) Xiang Wang et al.   PLoS One

Long-distance electrical coupling via tunneling nanotubes

(2011) Xiang Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

MICALs in control of the cytoskeleton, exocytosis, and cell death

(2011) Yeping Zhou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exosomes and Cancer: A Newly Described Pathway of Immune Suppression

(2011) H.-G. Zhang et al.   CLINICAL CANCER RESEARCH

Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer

(2011) Adrien Acquistapace et al.   STEM CELLS

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels

(2010) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission

(2010) N. Van Prooyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes

(2009) Peter D Arkwright et al.   CELL RESEARCH

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

Control of mitochondrial transport and localization in neurons

(2009) Andrew F. MacAskill et al.   TRENDS IN CELL BIOLOGY

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

(2008) E.A. Eugenin et al.   CELLULAR IMMUNOLOGY

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY