The role of metabolism and tunneling nanotube-mediated intercellular mitochondria exchange in cancer drug resistance

Mitochondrial transfer between cells: Methodological constraints in cell culture and animal models

(2018) M.V. Berridge et al.   ANALYTICAL BIOCHEMISTRY

Intercellular mitochondria trafficking highlighting the dual role of mesenchymal stem cells as both sensors and rescuers of tissue injury

(2018) Anne-Marie Rodriguez et al.   CELL CYCLE

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Hexokinase 2 confers resistance to cisplatin in ovarian cancer cells by enhancing cisplatin-induced autophagy

(2018) Xiao-Yan Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

New Insights into the Tumor Microenvironment Utilizing Protein Array Technology

(2018) Wei Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

(2018) Jiancheng Wang et al.   Journal of Hematology & Oncology

Miro1 Enhances Mitochondria Transfer from Multipotent Mesenchymal Stem Cells (MMSC) to Neural Cells and Improves the Efficacy of Cell Recovery

(2018) Valentina Babenko et al.   MOLECULES

Intercellular transfer of mitochondria rescues virus-induced cell death but facilitates cell-to-cell spreading of porcine reproductive and respiratory syndrome virus

(2018) Rui Guo et al.   VIROLOGY

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

(2018) Alexia Karen Cotte et al.   Nature Communications

Macrophage conditioned medium induced cellular network formation in MCF-7 cells through enhanced tunneling nanotube formation and tunneling nanotube mediated release of viable cytoplasmic fragments

(2017) Pooja Patheja et al.   EXPERIMENTAL CELL RESEARCH

Metformin increases sensitivity of osteosarcoma stem cells to cisplatin by inhibiting expression of PKM2

(2017) Depeng Shang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

TNT-Induced Phagocytosis: Tunneling Nanotubes Mediate the Transfer of Pro-Phagocytic Signals From Apoptotic to Viable Cells

(2017) Margarethe Bittins et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation

(2017) Mark Kin Fai Ma et al.   JOURNAL OF HEPATOLOGY

Mesenchymal stem cells: key players in cancer progression

(2017) Sarah M. Ridge et al.   Molecular Cancer

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

(2017) Xiangjun Kong et al.   NATURE

How the Internet of cells has biologists buzzing

(2017) Monya Baker   NATURE

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

(2017) Elodie M Kuntz et al.   NATURE MEDICINE

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

(2017) A Noto et al.   ONCOGENE

MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression

(2017) Jiangman Duan et al.   ONCOLOGY REPORTS

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

(2017) Pasquale Sansone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic implications of tumor interstitial acidification

(2017) Iryna Kolosenko et al.   SEMINARS IN CANCER BIOLOGY

Characterization of Tunneling Nanotubes in Wharton’s jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells

(2017) Viviana Sanchez et al.   Stem Cell Reviews and Reports

Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming

(2017) Haymanti Bhanot et al.   Oncotarget

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer

(2017) Xiaoling Qian et al.   Oncotarget

Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

(2017) Inés Sáenz-de-Santa-María et al.   Oncotarget

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

(2017) Amrita Kumar et al.   Scientific Reports

miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling

(2017) Rita El Helou et al.   Cell Reports

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Characterization of Tunneling Nanotubes in Wharton’s jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells

(2017) Viviana Sanchez et al.   Stem Cell Reviews and Reports

Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications

(2017) Eunice Yuen-Ting Lau et al.   Stem Cells International

Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

(2017) Jennifer Ariazi et al.   Frontiers in Molecular Neuroscience

Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective

(2017) Wuzhen Chen et al.   Journal of Immunology Research

MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells

(2017) Brice Nzigou Mombo et al.   Jove-Journal of Visualized Experiments

Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma

(2017) Marta Anna Kowalik et al.   Frontiers in Oncology

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

(2016) R. Moschoi et al.   BLOOD

Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis

(2016) Kenji Kawai et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The biology and function of exosomes in cancer

(2016) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages

(2016) Michihiro Hashimoto et al.   JOURNAL OF IMMUNOLOGY

Overcoming cetuximab resistance in Ewing's sarcoma by inhibiting lactate dehydrogenase-A

(2016) JIAXIN FU et al.   Molecular Medicine Reports

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS

(2016) Megan V. Jackson et al.   STEM CELLS

Exosome-Mediated Metastasis: From Epithelial–Mesenchymal Transition to Escape from Immunosurveillance

(2016) Nicholas Syn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage

(2016) Dan Jiang et al.   Cell Death & Disease

Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML)

(2016) Maria Omsland et al.   Oncotarget

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

(2016) Snider Desir et al.   Oncotarget

Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics

(2016) Paloma Navarro et al.   Cell Reports

ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

(2016) Sunghee Park et al.   Cell Reports

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

iPSC-MSCs with High Intrinsic MIRO1 and Sensitivity to TNF-α Yield Efficacious Mitochondrial Transfer to Rescue Anthracycline-Induced Cardiomyopathy

(2016) Yuelin Zhang et al.   Stem Cell Reports

The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin

(2016) Emil Andreev et al.   Scientific Reports

Mitochondrial DNA: A disposable genome?

(2015) Inna N. Shokolenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

(2015) R. Polak et al.   BLOOD

Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

(2015) Colin A. Flaveny et al.   CANCER CELL

Tetracycline Antibiotics Impair Mitochondrial Function and Its Experimental Use Confounds Research

(2015) Iliana A. Chatzispyrou et al.   CANCER RESEARCH

L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation

(2015) Waldemar Wagner et al.   Cell Communication and Signaling

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

(2015) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

(2015) Valéry L. Payen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes

(2015) Anne Burtey et al.   FASEB JOURNAL

Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

(2015) Julie V. Philley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bone marrow-derived mesenchymal stem cells rescue injured H9c2 cells via transferring intact mitochondria through tunneling nanotubes in an in vitro simulated ischemia/reperfusion model

(2015) HUI HAN et al.   Molecular Medicine Reports

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

Toward understanding and exploiting tumor heterogeneity

(2015) Ash A Alizadeh et al.   NATURE MEDICINE

Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

(2015) Noemi Andor et al.   NATURE MEDICINE

Comparative proteomics analysis of differential proteins in respond to doxorubicin resistance in myelogenous leukemia cell lines

(2015) Shi Qinghong et al.   Proteome Science

Broad targeting of resistance to apoptosis in cancer

(2015) Ramzi M. Mohammad et al.   SEMINARS IN CANCER BIOLOGY

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Evolutionary Determinants of Cancer

(2015) M. Greaves   Cancer Discovery

Metabolic alteration – Overcoming therapy resistance in gastric cancer via PGK-1 inhibition in a combined therapy with standard chemotherapeutics

(2015) Carl Christoph Schneider et al.   International Journal of Surgery

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

(2015) Daniela Catanzaro et al.   Oncotarget

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR

(2015) Sue Ellen Verbrugge et al.   Oncotarget

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease

(2015) Rebecca Lamb et al.   Oncotarget

MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function

(2015) Andrés Caicedo et al.   Scientific Reports

Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells

(2015) Yu Mi Woo et al.   PLoS One

Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression

(2015) Gloria Perazzoli et al.   PLoS One

17β-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells

(2015) Paul K. Wright et al.   Oncotarget

Mitochondrial Transfer of Induced Pluripotent Stem Cell–Derived Mesenchymal Stem Cells to Airway Epithelial Cells Attenuates Cigarette Smoke–Induced Damage

(2014) Xiang Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells

(2014) Tae Hoon Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial dysfunction in cancer chemoresistance

(2014) Nicoletta Guaragnella et al.   BIOCHEMICAL PHARMACOLOGY

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy

(2014) Tanveer Ahmad et al.   EMBO JOURNAL

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

(2014) Venugopal Thayanithy et al.   EXPERIMENTAL CELL RESEARCH

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

(2014) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Inhibition of lactate dehydrogenase A by microRNA-34a resensitizes colon cancer cells to 5-fluorouracil

(2014) XIANGYONG LI et al.   Molecular Medicine Reports

The Expression of Genes Involved in Hepatocellular Carcinoma Chemoresistance Is Affected by Mitochondrial Genome Depletion

(2014) Ester Gonzalez-Sanchez et al.   MOLECULAR PHARMACEUTICS

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes

(2014) J P Webber et al.   ONCOGENE

Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis

(2014) S Josson et al.   ONCOGENE

Role of aldolase A in osteosarcoma progression and metastasis: In vitro and in vivo evidence

(2014) FENG LONG et al.   ONCOLOGY REPORTS

Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs

(2014) Wei-xian Chen et al.   PLoS One

Long-Distance Communication between Laryngeal Carcinoma Cells

(2014) Ieva Antanavičiūtė et al.   PLoS One

Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment

(2014) Do-Young Choi et al.   PROTEOMICS

Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

(2014) Venugopal Thayanithy et al.   Translational Research

Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein

(2014) Meng-meng Lv et al.   TUMOR BIOLOGY

Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes

(2014) Justin W. Ady et al.   Frontiers in Physiology

INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells

(2013) Joong Won Min et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

(2013) Camilla A. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

(2013) Hiroko Tadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production

(2013) Hailan Liu et al.   JOURNAL OF LIPID RESEARCH

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

(2013) Jennifer Pasquier et al.   Journal of Translational Medicine

ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38

(2013) Y. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

(2013) Meghna Das Thakur et al.   NATURE

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

(2012) Dolores Di Vizio et al.   AMERICAN JOURNAL OF PATHOLOGY

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

The homing of human cord blood stem cells to sites of inflammation

(2012) Kiran Kumar Velpula et al.   CELL CYCLE

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate

(2012) Chiara Riganti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Classification of mitocans, anti-cancer drugs acting on mitochondria

(2012) Jiri Neuzil et al.   MITOCHONDRION

Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel

(2012) Isabel R. Schlaepfer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen Promotes Prostate Cancer Cell Migration via Paracrine Release of ENO1 from Stromal Cells

(2012) Lin Yu et al.   MOLECULAR ENDOCRINOLOGY

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer

(2012) YU WANG et al.   ONCOLOGY REPORTS

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma

(2012) Emil Lou et al.   PLoS One

Vascular Smooth Muscle Cells Initiate Proliferation of Mesenchymal Stem Cells by Mitochondrial Transfer via Tunneling Nanotubes

(2012) Krishna C. Vallabhaneni et al.   STEM CELLS AND DEVELOPMENT

Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity

(2011) Manuela Polimeni et al.   BIOCHEMICAL JOURNAL

The awakening of an advanced malignant cancer: An insult to the mitochondrial genome

(2011) Cody C. Cook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Active Generation and Propagation of Ca2+ Signals within Tunneling Membrane Nanotubes

(2011) Ian F. Smith et al.   BIOPHYSICAL JOURNAL

Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

(2011) Jeanine M.L. Roodhart et al.   CANCER CELL

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

(2011) M. A. Antonyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer

(2011) Adrien Acquistapace et al.   STEM CELLS

Approaches for targeting mitochondria in cancer therapy

(2010) Gerard G.M. D'Souza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture

(2010) Egor Y. Plotnikov et al.   EXPERIMENTAL CELL RESEARCH

Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol

(2010) Ming Zhou et al.   Molecular Cancer

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

(2010) F Zhao et al.   ONCOGENE

Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells

(2009) Numsen Hail et al.   APOPTOSIS

Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease

(2009) Dolores Di Vizio et al.   CANCER RESEARCH

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells

(2009) Nickolay V. Bukoreshtliev et al.   FEBS LETTERS

Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas

(2009) Marie E. Beckner et al.   INTERNATIONAL JOURNAL OF CANCER

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

(2008) D. Trachootham et al.   BLOOD

Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability

(2008) Wan Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

(2008) Kaori Ishikawa et al.   FEBS LETTERS

Cell-to-cell cross-talk between mesenchymal stem cells and cardiomyocytes in co-culture

(2008) E. Y. Plotnikov et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY