The missing link: does tunnelling nanotube-based supercellularity provide a new understanding of chronic and lifestyle diseases?

Filopodia and Viruses: An Analysis of Membrane Processes in Entry Mechanisms

(2016) Kenneth Chang et al.   Frontiers in Microbiology

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

(2015) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

Emerging physiological and pathological implications of tunneling nanotubes formation between cells

(2015) Sajjad Sisakhtnezhad et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cell protrusions induced by hyaluronan synthase 3 (HAS3) resemble mesothelial microvilli and share cytoskeletal features of filopodia

(2015) Ville Koistinen et al.   EXPERIMENTAL CELL RESEARCH

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

Metabolic cross-feeding via intercellular nanotubes among bacteria

(2015) Samay Pande et al.   Nature Communications

Tunneling nanotubes between rat primary astrocytes and C6 glioma cells alter proliferation potential of glioma cells

(2015) Lei Zhang et al.   Neuroscience Bulletin

The receptor for advanced glycation end-products (RAGE) plays a key role in the formation of nanotubes (NTs) between peritoneal mesothelial cells and in murine kidneys

(2014) Julia Ranzinger et al.   CELL AND TISSUE RESEARCH

Matrix as an Interstitial Transport System

(2014) Dong Fan et al.   CIRCULATION RESEARCH

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy

(2014) Tanveer Ahmad et al.   EMBO JOURNAL

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

(2014) Venugopal Thayanithy et al.   EXPERIMENTAL CELL RESEARCH

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II + Cells in the Mouse Cornea

(2014) Holly R. Chinnery et al.   JOURNAL OF IMMUNOLOGY

Complement Activation on B Lymphocytes Opsonized with Rituximab or Ofatumumab Produces Substantial Changes in Membrane Structure Preceding Cell Lysis

(2014) P. V. Beum et al.   JOURNAL OF IMMUNOLOGY

Influenza A Virus Uses Intercellular Connections To Spread to Neighboring Cells

(2014) Kari L. Roberts et al.   JOURNAL OF VIROLOGY

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

(2014) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

(2014) Amin Ardestani et al.   NATURE MEDICINE

Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

(2014) Venugopal Thayanithy et al.   Translational Research

Cholesterol oxidase from Bordetella species promotes irreversible cell apoptosis in lung adenocarcinoma by cholesterol oxidation

(2014) J Liu et al.   Cell Death & Disease

Fungal Communication Requires the MAK-2 Pathway Elements STE-20 and RAS-2, the NRC-1 Adapter STE-50 and the MAP Kinase Scaffold HAM-5

(2014) Anne Dettmann et al.   PLoS Genetics

Callose homeostasis at plasmodesmata: molecular regulators and developmental relevance

(2014) Nico De Storme et al.   Frontiers in Plant Science

Microtubules and Their Role in Cellular Stress in Cancer

(2014) Amelia L. Parker et al.   Frontiers in Oncology

Effects of oxysterols on the blood–brain barrier: Implications for Alzheimer’s disease

(2013) Fabien Gosselet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxysterols in cancer cell proliferation and death

(2013) Jan de Weille et al.   BIOCHEMICAL PHARMACOLOGY

Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond

(2013) Gurdip Daffu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

(2013) Jennifer Pasquier et al.   Journal of Translational Medicine

Therapeutic Targeting of Tumor Growth and Angiogenesis with a Novel Anti-S100A4 Monoclonal Antibody

(2013) Jose Luis Hernández et al.   PLoS One

Mst1 and Mst2 kinases: regulations and diseases

(2013) Funiu Qin et al.   Cell and Bioscience

Mitochondria and FOXO3: breath or die

(2013) Judith Hagenbuchner et al.   Frontiers in Physiology

Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species

(2012) Peter Kovacic et al.   Current Neuropharmacology

Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress

(2012) Bhaskar Ponugoti et al.   Experimental Diabetes Research

Metformin Inhibits Advanced Glycation End Products (AGEs)-induced Renal Tubular Cell Injury by Suppressing Reactive Oxygen Species Generation via Reducing Receptor for AGEs (RAGE) Expression

(2012) Y. Ishibashi et al.   HORMONE AND METABOLIC RESEARCH

Different Modalities of Intercellular Membrane Exchanges Mediate Cell-to-cell P-glycoprotein Transfers in MCF-7 Breast Cancer Cells

(2012) Jennifer Pasquier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of Cholesterol on the Phase Transition of Lipid Bilayers: A Temperature-Controlled Force Spectroscopy Study

(2012) Lorena Redondo-Morata et al.   LANGMUIR

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Intercellular (Mis)communication in Neurodegenerative Disease

(2012) Gwenn A. Garden et al.   NEURON

Mesenchymal Stem Cells Transfer Mitochondria to the Cells with Virtually No Mitochondrial Function but Not with Pathogenic mtDNA Mutations

(2012) Young Min Cho et al.   PLoS One

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma

(2012) Emil Lou et al.   PLoS One

Fas Signalling Promotes Intercellular Communication in T Cells

(2012) Francesca Luchetti et al.   PLoS One

Cell-to-cell movement of plastids in plants

(2012) G. Thyssen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

Tunneling-nanotube direction determination in neurons and astrocytes

(2012) X Sun et al.   Cell Death & Disease

Microtubule-targeted agents: When mitochondria become essential to chemotherapy

(2011) A. Rovini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Interplay between FOXO, TOR, and Akt

(2011) Nissim Hay   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Consequences of cell-to-cell P-glycoprotein transfer on acquired multidrug resistance in breast cancer: a cell population dynamics model

(2011) Jennifer Pasquier et al.   Biology Direct

The cytoskeleton in plasmodesmata: a role in intercellular transport?

(2011) R. G. White et al.   JOURNAL OF EXPERIMENTAL BOTANY

Redox States of Plastids and Mitochondria Differentially Regulate Intercellular Transport via Plasmodesmata

(2011) S. Stonebloom et al.   PLANT PHYSIOLOGY

Regulation of Solute Flux through Plasmodesmata in the Root Meristem

(2011) H. L. Rutschow et al.   PLANT PHYSIOLOGY

Nanotube Action between Human Mesothelial Cells Reveals Novel Aspects of Inflammatory Responses

(2011) Julia Ranzinger et al.   PLoS One

Mitochondrial Capture by a Transmissible Cancer

(2011) C. A. Rebbeck et al.   SCIENCE

Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer

(2011) Adrien Acquistapace et al.   STEM CELLS

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse

(2010) Nina Reiniger et al.   DIABETES

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Methyl-β-cyclodextrin Suppresses Hyaluronan Synthesis by Down-regulation of Hyaluronan Synthase 2 through Inhibition of Akt

(2010) Anne Kultti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hen or Egg?

(2009) Amin Rustom   Annals of the New York Academy of Sciences

Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes

(2009) Peter D Arkwright et al.   CELL RESEARCH

The DeMSTification of Mammalian Ste20 Kinases

(2009) Maria Radu et al.   CURRENT BIOLOGY

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prions tunnel between cells

(2009) Hans-Hermann Gerdes   NATURE CELL BIOLOGY

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

HIV-1 hijacks tunneling nanotubes and secretory microvesicles for intercellular spread in monocyte-derived macrophages

(2009) Irena Kadiu et al.   Retrovirology

Mitochondrial generation of free radicals and hypoxic signaling

(2009) Robert O. Poyton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

(2008) E.A. Eugenin et al.   CELLULAR IMMUNOLOGY

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY