Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming

Safety and Effectiveness of the Prolonged Treatment of Children with a Ketogenic Diet

(2020) Jana Ruiz Herrero et al.   Nutrients

Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

(2020) Boyoung Shin et al.   Cell Reports

Obesity and COVID-19: Molecular Mechanisms Linking Both Pandemics

(2020) Andreas Ritter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of carbohydrate-reduced nutrition in septic patients on ICU: study protocol for a prospective randomised controlled trial

(2020) Tim Rahmel et al.   BMJ Open

Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

(2020) Jennifer R. Habel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

(2020) Gladys Ferrere et al.   JCI Insight

The Roles of Mitochondrial SIRT4 in Cellular Metabolism

(2019) Zheying Min et al.   Frontiers in Endocrinology

Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome

(2019) Brooke A. Napier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes

(2019) Bolla et al.   Nutrients

T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate

(2019) Kun-Po Li et al.   CELL DEATH AND DIFFERENTIATION

Identification of suitable controls for miRNA quantification in T-cells and whole blood cells in sepsis

(2019) Simon Hirschberger et al.   Scientific Reports

Oncogenic pathways and the electron transport chain: a dangeROS liaison

(2019) Vittoria Raimondi et al.   BRITISH JOURNAL OF CANCER

Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development

(2019) Huafeng Zhang et al.   NATURE CELL BIOLOGY

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

(2018) Anette Christ et al.   CELL

Mitochondrial activity in T cells

(2018) Gabriela Desdín-Micó et al.   MITOCHONDRION

Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism

(2018) Davide G. Franchina et al.   TRENDS IN IMMUNOLOGY

Effects of the Ketogenic diet in overweight divers breathing Enriched Air Nitrox

(2018) Gerardo Bosco et al.   Scientific Reports

The Challenge of Reforming Nutritional Epidemiologic Research

(2018) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study

(2018) Mahshid Dehghan et al.   LANCET

Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity

(2018) Marie Liebmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of a short-term low-carbohydrate, high-fat diet with or without postmeal walks on glycemic control and inflammation in type 2 diabetes: a randomized trial

(2018) Étienne Myette-Côté et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Is the PURE study pure fiction?

(2018) Edward Archer et al.   EUROPEAN HEART JOURNAL

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

(2018) P Möhnle et al.   MOLECULAR MEDICINE

Foundations of Immunometabolism and Implications for Metabolic Health and Disease

(2017) Gökhan S. Hotamisligil   IMMUNITY

Increased risk of influenza among vaccinated adults who are obese

(2017) S D Neidich et al.   INTERNATIONAL JOURNAL OF OBESITY

Press-pulse: a novel therapeutic strategy for the metabolic management of cancer

(2017) Thomas N. Seyfried et al.   Nutrition & Metabolism

The mitochondrial dynamics in cancer and immune-surveillance

(2017) Luca Simula et al.   SEMINARS IN CANCER BIOLOGY

β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares

(2017) Emily L. Goldberg et al.   Cell Reports

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

Lifespan Weighed Down by Diet

(2016) David S. Ludwig   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

(2015) Dania C. Liemburg-Apers et al.   ARCHIVES OF TOXICOLOGY

Effects of n-3 Polyunsaturated Fatty Acids (ω-3) Supplementation on Some Cardiovascular Risk Factors with a Ketogenic Mediterranean Diet

(2015) Antonio Paoli et al.   Marine Drugs

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

(2015) Yun-Hee Youm et al.   NATURE MEDICINE

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Statistical review of US macronutrient consumption data, 1965–2011: Americans have been following dietary guidelines, coincident with the rise in obesity

(2015) Evan Cohen et al.   NUTRITION

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

(2014) Andrew N. Macintyre et al.   Cell Metabolism

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits

(2014) Michael Ristow   NATURE MEDICINE

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Meal frequency and timing in health and disease

(2014) Mark P. Mattson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ketone body metabolism and cardiovascular disease

(2013) David G. Cotter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Immunological Goings-on in Visceral Adipose Tissue

(2013) Diane Mathis   Cell Metabolism

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

(2013) A Paoli et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Mitochondrial ROS Fire Up T Cell Activation

(2013) Michael P. Murphy et al.   IMMUNITY

CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability

(2013) G. J. W. van der Windt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Metabolic reprogramming and metabolic dependency in T cells

(2012) Ruoning Wang et al.   IMMUNOLOGICAL REVIEWS

T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation

(2012) Marcin M. Kamiński et al.   Cell Reports

Modulation of oxidative stress and mitochondrial function by the ketogenic diet

(2011) Julie Milder et al.   EPILEPSY RESEARCH

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

The structure and allosteric regulation of glutamate dehydrogenase

(2010) Ming Li et al.   NEUROCHEMISTRY INTERNATIONAL

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

(2010) J. Kwon et al.   Science Signaling