Treatment options for infections caused by carbapenem-resistantEnterobacteriaceae: can we apply “precision medicine” to antimicrobial chemotherapy?

IncA/C Plasmid CarryingblaNDM-1,blaCMY-16, andfosA3in a Salmonella enterica Serovar Corvallis Strain Isolated from a Migratory Wild Bird in Germany

(2015) L. Villa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preliminary Clinical Study of the Effect of Ascorbic Acid on Colistin-Associated Nephrotoxicity

(2015) Rujipas Sirijatuphat et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial treatment and outcomes of critically ill patients with OXA-48like carbapenemase-producing Enterobacteriaceae infections

(2015) Warren Lowman et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Dissemination of a clone carrying a fosA3-harbouring plasmid mediates high fosfomycin resistance rate of KPC-producing Klebsiella pneumoniae in China

(2015) Yan Jiang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

(2015) Alexis Tabah et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study

(2015) Mario Tumbarello et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Colistin: How should It Be Dosed for the Critically Ill?

(2015) Cornelia Landersdorfer et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

(2015) Daniel Nichol et al.   PLoS Computational Biology

Surveillance of Carbapenem-Resistant Klebsiella pneumoniae: Tracking Molecular Epidemiology and Outcomes through a Regional Network

(2014) David van Duin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VivoEfficacy of Humanized Exposures of Ceftazidime-Avibactam in Comparison with Ceftazidime against Contemporary Enterobacteriaceae Isolates

(2014) Shawn H. MacVane et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenem-Resistant Klebsiella pneumoniae Strains Exhibit Diversity in Aminoglycoside-Modifying Enzymes, Which Exert Differing Effects on Plazomicin and Other Agents

(2014) Reem Almaghrabi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High Incidence and Endemic Spread of NDM-1-Positive Enterobacteriaceae in Henan Province, China

(2014) Shangshang Qin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Structure of KPC-Producing Klebsiella pneumoniae Isolates from Midwestern U.S. Hospitals

(2014) Meredith S. Wright et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VivoEvolution to Colistin Resistance by PmrB Sensor Kinase Mutation in KPC-Producing Klebsiella pneumoniae Is Associated with Low-Dosage Colistin Treatment

(2014) Antonio Cannatelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Characterization of Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae in the Countries of the Gulf Cooperation Council: Dominance of OXA-48 and NDM Producers

(2014) Hosam M. Zowawi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomic and Transcriptomic Analyses of Colistin-Resistant Clinical Isolates of Klebsiella pneumoniae Reveal Multiple Pathways of Resistance

(2014) Meredith S. Wright et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenemase-Producing Klebsiella pneumoniae Bloodstream Infections: Lowering Mortality by Antibiotic Combination Schemes and the Role of Carbapenems

(2014) George L. Daikos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin®

(2014) Timothy A. Blizzard et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antibiotic-Resistant Gram-Negative Bacterial Infections in Patients With Cancer

(2014) Federico Perez et al.   CLINICAL INFECTIOUS DISEASES

Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance

(2014) D. van Duin et al.   CLINICAL MICROBIOLOGY AND INFECTION

Options for treating carbapenem-resistant Enterobacteriaceae

(2014) Petros I. Rafailidis et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Dual beta-lactam therapy for serious Gram-negative infections: is it time to revisit?

(2014) Christine Rahme et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Ceftazidime-avibactam and comparator agents tested against urinary tract isolates from a global surveillance program (2011)

(2014) Robert K. Flamm et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The role of tigecycline in the treatment of infections in light of the new black box warning

(2014) Deepali Dixit et al.   Expert Review of Anti-Infective Therapy

Carbapenemase-producing Enterobacteriaceae in a tertiary hospital in Madrid, Spain: high percentage of colistin resistance among VIM-1-producing Klebsiella pneumoniae ST11 isolates

(2014) Irene Pena et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Blood stream infections due to OXA-48-like carbapenemase-producing Enterobacteriaceae: treatment and survival

(2014) Ilker Inanç Balkan et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Countrywide spread of OXA-48 carbapenemase in Lebanon: surveillance and genetic characterization of carbapenem-non-susceptible Enterobacteriaceae in 10 hospitals over a one-year period

(2014) D. Hammoudi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

New Delhi Metallo-β-Lactamase–Producing Carbapenem-ResistantEscherichia coliAssociated With Exposure to Duodenoscopes

(2014) Lauren Epstein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Combination therapy for carbapenem-resistant Gram-negative bacteria

(2014) M. Paul et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Tigecycline in treatment of multidrug-resistant Gram-negative bacillus urinary tract infections: a systematic review

(2014) K. Brust et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Persistence of Klebsiella pneumoniae ST258 as the predominant clone of carbapenemase-producing Enterobacteriaceae in post-acute-care hospitals in Israel, 2008-13

(2014) A. Adler et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae

(2014) L. Poirel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Fosfomycin Susceptibility in Carbapenem-Resistant Enterobacteriaceae from Germany

(2014) M. Kaase et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multistate Point-Prevalence Survey of Health Care–Associated Infections

(2014) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular dissection of the evolution of carbapenem-resistant multilocus sequence type 258Klebsiella pneumoniae

(2014) Frank R. DeLeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of resistance development against drug combinations by collateral responses to component drugs

(2014) C. Munck et al.   Science Translational Medicine

Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

(2014) Abiola O. Olaitan et al.   Frontiers in Microbiology

In VivoEmergence of Colistin Resistance in Klebsiella pneumoniae Producing KPC-Type Carbapenemases Mediated by Insertional Inactivation of the PhoQ/PhoPmgrBRegulator

(2013) Antonio Cannatelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of Porin Expression in Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae Identifies Isolates Most Susceptible to the Combination of Colistin and Carbapenems

(2013) Jae H. Hong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Systematic Review and Meta-Analysis ofIn VitroSynergy of Polymyxins and Carbapenems

(2013) Oren Zusman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivities of Ceftazidime-Avibactam and Aztreonam-Avibactam against 372 Gram-Negative Bacilli Collected in 2011 and 2012 from 11 Teaching Hospitals in China

(2013) Xiaojuan Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomics of KPC-Producing Klebsiella pneumoniae Sequence Type 512 Clone Highlights the Role of RamR and Ribosomal S10 Protein Mutations in Conferring Tigecycline Resistance

(2013) Laura Villa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World

(2013) Sarah M. Drawz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of Humanized Carbapenem and Ceftazidime Regimens against Enterobacteriaceae Producing OXA-48 Carbapenemase in a Murine Infection Model

(2013) Dora E. Wiskirchen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenemase-Producing Enterobacteriaceae in Spain in 2012

(2013) Jesús Oteo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic Treatment of Infections Due to Carbapenem-Resistant Enterobacteriaceae: Systematic Evaluation of the Available Evidence

(2013) Matthew E. Falagas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Activity of Ceftazidime-Avibactam against Gram-Negative Organisms Collected from U.S. Medical Centers in 2012

(2013) Helio S. Sader et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenem-resistant Enterobacteriaceae: A menace to our most vulnerable patients

(2013) F. Perez et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Tigecycline: an update

(2013) Gary E. Stein et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Molecular characteristics of carbapenemase-producing Enterobacteriaceae in China from 2008 to 2011: Predominance of KPC-2 enzyme

(2013) Henan Li et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Predictors of mortality in multidrug-resistantKlebsiella pneumoniaebloodstream infections

(2013) Pierluigi Viale et al.   Expert Review of Anti-Infective Therapy

How many outbreaks of nosocomial infections occur in German neonatal intensive care units annually?

(2013) F. Schwab et al.   INFECTION

Dissemination of the KPC-2 carbapenemase in non-Klebsiella pneumoniae enterobacterial isolates from Colombia

(2013) Gaelle Cuzon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Outcomes of critically ill intensive care unit patients treated with fosfomycin for infections due to pandrug-resistant and extensively drug-resistant carbapenemase-producing Gram-negative bacteria

(2013) Konstantinos Pontikis et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Prescription behaviours for tigecycline in real-life clinical practice from five European observational studies

(2013) M. Bassetti et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial

(2013) Christopher Lucasti et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

(2013) L Silvia Munoz-Price et al.   LANCET INFECTIOUS DISEASES

Treatment Outcome of Bacteremia Due to KPC-Producing Klebsiella pneumoniae: Superiority of Combination Antimicrobial Regimens

(2012) Zubair A. Qureshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tigecycline Resistance Can Occur Independently of theramAGene in Klebsiella pneumoniae

(2012) Mark Veleba et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of Ceftaroline-Avibactam Tested against Gram-Negative Organism Populations, including Strains Expressing One or More β-Lactamases and Methicillin-Resistant Staphylococcus aureus Carrying Various Staphylococcal Cassette ChromosomemecTypes

(2012) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Combination of Doripenem and Colistin Is Bactericidal and Synergistic against Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae

(2012) Meredith G. Jernigan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of Klebsiella pneumoniae Coharboring KPC and VIM Carbapenemases in Colombia

(2012) L. J. Rojas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Experience with Fosfomycin for Treatment of Urinary Tract Infections Due to Multidrug-Resistant Organisms

(2012) Elizabeth A. Neuner et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Outcomes With Extended or Continuous Versus Short-term Intravenous Infusion of Carbapenems and Piperacillin/Tazobactam: A Systematic Review and Meta-analysis

(2012) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Importance of Combination Therapy

(2012) M. Tumbarello et al.   CLINICAL INFECTIOUS DISEASES

Continuous Infusion of Beta-Lactam Antibiotics in Severe Sepsis: A Multicenter Double-Blind, Randomized Controlled Trial

(2012) J. M. Dulhunty et al.   CLINICAL INFECTIOUS DISEASES

Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria

(2012) M. Akova et al.   CLINICAL MICROBIOLOGY AND INFECTION

Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions

(2012) L. S. Tzouvelekis et al.   CLINICAL MICROBIOLOGY REVIEWS

Efficacy and safety of ceftazidime–avibactam versus imipenem–cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study

(2012) José A. Vazquez et al.   CURRENT MEDICAL RESEARCH AND OPINION

Pharmacokinetics and pharmacodynamics of ‘old’ polymyxins: what is new?

(2012) Phillip J. Bergen et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin

(2012) George G Zhanel et al.   Expert Review of Anti-Infective Therapy

Trends in Aminoglycoside Use and Gentamicin-Resistant Gram-Negative Clinical Isolates in US Academic Medical Centers: Implications for Antimicrobial Stewardship

(2012) Mera Ababneh et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

OXA-48-like carbapenemases: the phantom menace

(2012) L. Poirel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of Plazomicin (ACHN-490) against MDR clinical isolates ofKlebsiella pneumoniae, Escherichia coli, andEnterobacterspp. from Athens, Greece

(2012) Irene Galani et al.   JOURNAL OF CHEMOTHERAPY

Emergence of carbapenem-resistant Enterobacteriaceae as causes of bloodstream infections in patients with hematologic malignancies

(2012) Michael J. Satlin et al.   LEUKEMIA & LYMPHOMA

Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing

(2012) E. S. Snitkin et al.   Science Translational Medicine

Treatment of Klebsiella Pneumoniae Carbapenemase (KPC) infections: a review of published case series and case reports

(2012) Grace C Lee et al.   Annals of Clinical Microbiology and Antimicrobials

Melatonin Attenuates Colistin-Induced Nephrotoxicity in Rats

(2011) Jumana M. Yousef et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroInteractions of Antimicrobial Combinations with Fosfomycin against KPC-2-Producing Klebsiella pneumoniae and Protection of Resistance Development

(2011) Maria Souli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Double-Carbapenem Therapy for Carbapenemase-Producing Klebsiella pneumoniae

(2011) Catharine C. Bulik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in Critically Ill Patients from a Multicenter Study Provide Dosing Suggestions for Various Categories of Patients

(2011) S. M. Garonzik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Effectiveness of Aminoglycosides, Polymyxin B, and Tigecycline for Clearance of Carbapenem-Resistant Klebsiella pneumoniae from Urine

(2011) Michael J. Satlin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenems: Past, Present, and Future

(2011) Krisztina M. Papp-Wallace et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Containment of a Country-wide Outbreak of Carbapenem-Resistant Klebsiella pneumoniae in Israeli Hospitals via a Nationally Implemented Intervention

(2011) M. J. Schwaber et al.   CLINICAL INFECTIOUS DISEASES

Carbapenem Resistance in Klebsiella pneumoniae Due to the New Delhi Metallo- -lactamase

(2011) H. Sidjabat et al.   CLINICAL INFECTIOUS DISEASES

Colistin-Resistant, Klebsiella pneumoniae Carbapenemase (KPC)-Producing Klebsiella pneumoniae Belonging to the International Epidemic Clone ST258

(2011) T. Bogdanovich et al.   CLINICAL INFECTIOUS DISEASES

Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment

(2011) O. Zarkotou et al.   CLINICAL MICROBIOLOGY AND INFECTION

Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy

(2011) J. Findlay et al.   CLINICAL MICROBIOLOGY AND INFECTION

Synergy of fosfomycin with carbapenems, colistin, netilmicin, and tigecycline against multidrug-resistant Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa clinical isolates

(2011) G. Samonis et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Analysis of the Networks Controlling the Antimicrobial-Peptide-Dependent Induction of Klebsiella pneumoniae Virulence Factors

(2011) Enrique Llobet et al.   INFECTION AND IMMUNITY

In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae

(2011) Z. Aktaş et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The revival of fosfomycin

(2011) Argyris S. Michalopoulos et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Ascorbic acid protects against the nephrotoxicity and apoptosis caused by colistin and affects its pharmacokinetics

(2011) J. M. Yousef et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IMP-Producing Carbapenem-Resistant Klebsiella pneumoniae in the United States

(2011) B. M. Limbago et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Resistance to carbapenems in sequence type 11 Klebsiella pneumoniae is related to DHA-1 and loss of OmpK35 and/or OmpK36

(2011) S. Y. Shin et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-ProducingEnterobacteriaceae

(2010) David M. Livermore et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phenotypic and Biochemical Comparison of the Carbapenem-Hydrolyzing Activities of Five Plasmid-Borne AmpC  -Lactamases

(2010) H. Mammeri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of Ceftazidime and NXL104 in Two Murine Models of Infection Due to KPC-ProducingKlebsiella pneumoniae

(2010) Andrea Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Spread of OXA-48-Encoding Plasmid in Turkey and Beyond

(2010) A. Carrer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Outbreak of Colistin-Resistant, Carbapenem-ResistantKlebsiella pneumoniaein Metropolitan Detroit, Michigan

(2010) Dror Marchaim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Emerging carbapenemases: a global perspective

(2010) Timothy R. Walsh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination

(2010) F. Perez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates

(2010) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection

(2010) Elizabeth B. Hirsch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Evaluation of Antibiotic Synergy for Polymyxin B-Resistant Carbapenemase-Producing Klebsiella pneumoniae

(2010) A. Elemam et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 β-lactamase resistant to colistin

(2010) K. Kontopoulou et al.   JOURNAL OF HOSPITAL INFECTION

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin

(2009) A. Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibitor Resistance in the KPC-2  -Lactamase, a Preeminent Property of This Class A  -Lactamase

(2009) K. M. Papp-Wallace et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of NXL104 in Combination with  -Lactams against Klebsiella pneumoniae Isolates Producing KPC Carbapenemases

(2009) A. Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structure of the OXA-48 β-Lactamase Reveals Mechanistic Diversity among Class D Carbapenemases

(2009) Jean-Denis Docquier et al.   CHEMISTRY & BIOLOGY

Intravenous fosfomycin for the treatment of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae in critically ill patients: a prospective evaluation

(2009) A. Michalopoulos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Phylogenetic and genomic diversity of human bacteremic Escherichia coli strains

(2008) Françoise Jaureguy et al.   BMC GENOMICS

Fosfomycin: Use Beyond Urinary Tract and Gastrointestinal Infections

(2008) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetic and Pharmacodynamic Properties of Meropenem

(2008) David P. Nicolau   CLINICAL INFECTIOUS DISEASES

Polymyxins Revisited

(2008) D. Landman et al.   CLINICAL MICROBIOLOGY REVIEWS

Outcomes of Carbapenem-Resistant Klebsiella pneumoniae Infection and the Impact of Antimicrobial and Adjunctive Therapies

(2008) Gopi Patel et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Outbreak of Multidrug-Resistant Serratia marcescens Infection in a Neonatal Intensive Care Unit

(2008) Lisa L. Maragakis et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Tigecycline pharmacokinetic/pharmacodynamic update

(2008) A. P. MacGowan   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Drug interactions modulate the potential for evolution of resistance

(2008) J.-B. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA