Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis

Single-cell genomics of uncultured bacteria reveals dietary fiber responders in the mouse gut microbiota

(2020) Rieka Chijiiwa et al.   Microbiome

Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

(2020) Lianmin Chen et al.   Cell Reports

The role of the microbiota in human genetic adaptation

(2020) Taichi A. Suzuki et al.   SCIENCE

Taxonomic profiling and populational patterns of bacterial bile salt hydrolase (BSH) genes based on worldwide human gut microbiome

(2019) Ziwei Song et al.   Microbiome

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome

(2019) Xinyu Qi et al.   NATURE MEDICINE

T cell–mediated regulation of the microbiota protects against obesity

(2019) Charisse Petersen et al.   SCIENCE

Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

(2019) Rohit Loomba et al.   Cell Metabolism

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

(2019) Nupur K. Das et al.   Cell Metabolism

Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

(2019) Yi Duan et al.   NATURE

Different carbon sources result in differential activation of sigma B and stress resistance in Listeria monocytogenes

(2019) Natalia Crespo Tapia et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Mitochondrial cAMP-PKA signaling: What do we really know?

(2018) Yasmine Ould Amer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

G.I. pros: Antimicrobial defense in the gastrointestinal tract

(2018) Lawton K. Chung et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue

(2018) Laura A. Velazquez-Villegas et al.   Nature Communications

A selective gut bacterial bile salt hydrolase alters host metabolism

(2018) Lina Yao et al.   eLife

An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

(2018) Aliia R. Fatkhullina et al.   IMMUNITY

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

(2018) Lulu Sun et al.   NATURE MEDICINE

The role of hypoxia-inducible factors in metabolic diseases

(2018) Frank J. Gonzalez et al.   Nature Reviews Endocrinology

Blocking FSH induces thermogenic adipose tissue and reduces body fat

(2017) Peng Liu et al.   NATURE

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis

(2017) Cen Xie et al.   NATURE MEDICINE

High-Throughput Single-Cell Cultivation on Microfluidic Streak Plates

(2016) Cheng-Ying Jiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice

(2016) J-Y Yang et al.   Mucosal Immunology

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Targeting adipose tissue in the treatment of obesity-associated diabetes

(2016) Christine M. Kusminski et al.   NATURE REVIEWS DRUG DISCOVERY

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

(2015) Duy Tin Truong et al.   NATURE METHODS

Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques

(2015) Ming-Min Zheng et al.   PROCESS BIOCHEMISTRY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome

(2014) Amir Zarrinpar et al.   Cell Metabolism

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Tissue Specific Phosphorylation of Mitochondrial Proteins Isolated from Rat Liver, Heart Muscle, and Skeletal Muscle

(2013) Steffen Bak et al.   JOURNAL OF PROTEOME RESEARCH

An alternative sigma factor governs the principal sigma factor inStreptomyces griseus

(2013) Hiroshi Otani et al.   MOLECULAR MICROBIOLOGY

The Hypoxia-Inducible Factor-C/EBP  Axis Controls Ethanol-Mediated Hepcidin Repression

(2012) E. R. Anderson et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Creatine kinase regulation by reversible phosphorylation in frog muscle

(2009) Christopher A. Dieni et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Integrin  1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

(2009) T. Shibue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY