2-(Pyridin-2-yl)isopropyl (PIP) Amine: An Enabling Directing Group for Divergent and Asymmetric Functionalization of Unactivated Methylene C(sp3)–H Bonds
出版年份 2021 全文链接
标题
2-(Pyridin-2-yl)isopropyl (PIP) Amine: An Enabling Directing Group for Divergent and Asymmetric Functionalization of Unactivated Methylene C(sp3)–H Bonds
作者
关键词
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出版物
ACCOUNTS OF CHEMICAL RESEARCH
Volume 54, Issue 12, Pages 2750-2763
出版商
American Chemical Society (ACS)
发表日期
2021-05-22
DOI
10.1021/acs.accounts.1c00168
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Asymmetric Synthesis of γ-Lactams Containing α,β-Contiguous Stereocenters via Pd(II)-Catalyzed Cascade Methylene C(sp3)–H Alkenylation/Aza-Wacker Cyclization
- (2021) Le-Song Wu et al. ORGANIC LETTERS
- Bidentate Directing Groups: An Efficient Tool in C–H Bond Functionalization Chemistry for the Expedient Construction of C–C Bonds
- (2020) Supriya Rej et al. CHEMICAL REVIEWS
- Pd(II)‐Catalyzed Tandem Enantioselective Methylene C(sp3)–H Alkenylation/Aza‐Wacker Cyclization to Access β‐Stereogenic γ‐Lactams
- (2020) Yi Ding et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Acyclic Aliphatic Amides with Contiguous Stereogenic Centers via Pd‐Catalyzed Enantio‐, Chemo‐ and Diastereoselective Methylene C(sp3)‐H arylation
- (2020) Ye-Qiang Han et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Transition Metal‐Catalyzed Enantioselective C–H Functionalization via Chiral Transient Directing Group Strategy
- (2020) Gang Liao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pd(II)-Catalyzed Enantioselective Intramolecular Arylation of Unbiased C(sp3)–H Bonds to Construct Chiral Benzo-ring Compounds
- (2020) Ye-Qiang Han et al. ORGANIC LETTERS
- Palladium-Catalyzed C(sp3)–H Nitrooxylation with tert-Butyl Nitrite and Molecular Oxygen
- (2020) Bo Li et al. ORGANIC LETTERS
- Palladium-Catalyzed C(sp3)–H Bond Functionalization of Aliphatic Amines
- (2019) Chuan He et al. Chem
- Pd(II)-Catalyzed Enantioselective Alkynylation of Unbiased Methylene C(sp3)–H Bonds Using 3,3′-Fluorinated-BINOL as a Chiral Ligand
- (2019) Ye-Qiang Han et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enantio‐ and Diastereoswitchable C−H Arylation of Methylene Groups in Cycloalkanes
- (2019) Michal S. Andrä et al. CHEMISTRY-A EUROPEAN JOURNAL
- Synthesis of Chiral β‐Lactams by Pd‐Catalyzed Enantioselective Amidation of Methylene C(sp 3 )–H Bonds
- (2019) Tao Zhou et al. CHINESE JOURNAL OF CHEMISTRY
- Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation
- (2019) Hua-Rong Tong et al. ACS Catalysis
- Palladium(II)-Catalyzed Enantioselective Arylation of Unbiased Methylene C(sp3 )−H Bonds Enabled by a 2-Pyridinylisopropyl Auxiliary and Chiral Phosphoric Acids
- (2018) Sheng-Yi Yan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts
- (2018) Tyler G. Saint-Denis et al. SCIENCE
- sp3 C–H activation via exo-type directing groups
- (2018) Yan Xu et al. Chemical Science
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- (2018) Bhuttu Khan et al. Asian Journal of Organic Chemistry
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- Palladium-Catalyzed Direct Intermolecular Amination of Unactivated Methylene C(sp3)–H Bonds with Azodiformates via Bidentate-Chelation Assistance
- (2017) He-Yuan Bai et al. ACS Catalysis
- Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization
- (2016) Gang He et al. ACCOUNTS OF CHEMICAL RESEARCH
- Palladium-Catalyzed Transformations of Alkyl C–H Bonds
- (2016) Jian He et al. CHEMICAL REVIEWS
- Palladium-catalysed transannular C–H functionalization of alicyclic amines
- (2016) Joseph J. Topczewski et al. NATURE
- Ligand-accelerated enantioselective methylene C(sp3)–H bond activation
- (2016) Gang Chen et al. SCIENCE
- γ-Lactone Synthesis via Palladium(II)-Catalyzed Lactonization of Unactivated Methylene C(sp3)–H Bonds
- (2016) Bing-Feng Shi et al. SYNLETT
- A unified synthesis of cyclic ethers or lactones via Pd-catalyzed intramolecular O -functionalization of sp 3 C H bonds
- (2016) Haifeng Wang et al. TETRAHEDRON LETTERS
- Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds
- (2015) Olafs Daugulis et al. ACCOUNTS OF CHEMICAL RESEARCH
- A General and Scalable Synthesis of Aeruginosin Marine Natural Products Based on Two Strategic C(sp3)H Activation Reactions
- (2015) David Dailler et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Divergent Synthesis of Aeruginosins Based on a C(sp3)H Activation Strategy
- (2015) David Dailler et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2015) Kang Chen et al. CHEMISTRY-A EUROPEAN JOURNAL
- Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)–H Bonds: Scope and Mechanistic Studies
- (2015) Qi Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)–H Bonds
- (2015) Jinmin Miao et al. ORGANIC LETTERS
- Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids
- (2015) Shao-Bai Yan et al. ORGANIC LETTERS
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- (2014) Qing Gu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pd(ii)-Catalyzed arylation of unactivated methylene C(sp3)–H bonds with aryl halides using a removable auxiliary
- (2014) Qi Zhang et al. CHEMICAL COMMUNICATIONS
- Recent Progress in the Synthesis of Functionalized β-Lactams through Transition-Metal-Catalyzed C(sp3)–H Amidation
- (2014) Bing-Feng Shi et al. SYNLETT
- Stereoselective Synthesis of Chiral α-Amino-β-Lactams through Palladium(II)-Catalyzed Sequential Monoarylation/Amidation of C(sp3)H Bonds
- (2013) Qi Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Palladium-Catalyzed Unactivated C(sp3)–H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-Lactams
- (2013) Wen-Wu Sun et al. ORGANIC LETTERS
- Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′-F2-BINOL
- (2013) Yongda Zhang et al. ORGANIC LETTERS
- Pd(ii)-catalyzed alkoxylation of unactivated C(sp3)–H and C(sp2)–H bonds using a removable directing group: efficient synthesis of alkyl ethers
- (2013) Fa-Jie Chen et al. Chemical Science
- Recent development of direct asymmetric functionalization of inert C–H bonds
- (2013) Chao Zheng et al. RSC Advances
- Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions
- (2012) Shu-Yu Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ligand-Enabled Methylene C(sp3)–H Bond Activation with a Pd(II) Catalyst
- (2012) Masayuki Wasa et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds
- (2011) Olivier Baudoin CHEMICAL SOCIETY REVIEWS
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- (2011) Yusuke Ano et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Steric Crowding Makes Challenging Csp3–F Reductive Eliminations Feasible
- (2011) Shu-Bin Zhao et al. ORGANOMETALLICS
- Synthesis of the Leu–Trp Component of the Celogentin Family of Cyclic Peptides Through a C–H Activation–Cross-Coupling Strategy
- (2010) Barbara T. Y. Li et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds
- (2010) Dmitry Shabashov et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Total Synthesis of Celogentin C by Stereoselective CH Activation
- (2009) Yiqing Feng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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