Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

Pd(II)-Catalyzed Enantioselective C(sp3)–H Borylation

(2017) Jian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Origins of Dramatic Differences in Five-Membered vs Six-Membered Chelation of Pd(II) on Efficiency of C(sp3)–H Bond Activation

(2017) Yun-Fang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Enantioselective C–H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

(2017) Adam P. Smalley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir-Catalyzed Enantioselective, Intramolecular Silylation of Methyl C–H Bonds

(2017) Bo Su et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formation of α-chiral centers by asymmetric β-C(sp 3 )–H arylation, alkenylation, and alkynylation

(2017) Qing-Feng Wu et al.   SCIENCE

Palladium(0)-catalyzed asymmetric C(sp3)–H arylation using a chiral binol-derived phosphate and an achiral ligand

(2017) Lei Yang et al.   Chemical Science

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C−H Arylation of Amines Using a BINOL Phosphate Ligand

(2016) Hao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C−H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

(2016) Kai-Jiong Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Enantioselective Silylation of Cyclopropyl C−H Bonds

(2016) Taegyo Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Benzylamines via Palladium(II)-Catalyzed C–H Cross-Coupling

(2016) Kai-Jiong Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-selective and stereoselective functionalization of unactivated C–H bonds

(2016) Kuangbiao Liao et al.   NATURE

Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides

(2016) Pankaj Jain et al.   Nature Chemistry

Palladium(0)-Catalyzed Asymmetric C–H Alkenylation for Efficient Synthesis of Planar Chiral Ferrocenes

(2016) De-Wei Gao et al.   ORGANOMETALLICS

Functionalization of C(sp3)-H bonds using a transient directing group

(2016) F.-L. Zhang et al.   SCIENCE

Ligand-accelerated enantioselective methylene C(sp3)–H bond activation

(2016) Gang Chen et al.   SCIENCE

Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities

(2016) John F. Hartwig et al.   ACS Central Science

Enantioselective sp3 C–H alkylation of γ-butyrolactam by a chiral Ir(i) catalyst for the synthesis of 4-substituted γ-amino acids

(2015) Yu-ki Tahara et al.   CHEMICAL COMMUNICATIONS

A Combined IM-MS/DFT Study on [Pd(MPAA)]-Catalyzed Enantioselective CH Activation: Relay of Chirality through a Rigid Framework

(2015) Gui-Juan Cheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Acceleration Effects of Phosphine Ligands on the Rhodium-Catalyzed Dehydrogenative Silylation and Germylation of Unactivated C(sp3)–H Bonds

(2015) Masahito Murai et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium(II)-Catalyzed Highly Enantioselective C–H Arylation of Cyclopropylmethylamines

(2015) Kelvin S. L. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids

(2015) Shao-Bai Yan et al.   ORGANIC LETTERS

Efficient Pd0-Catalyzed Asymmetric Activation of Primary and Secondary C–H Bonds Enabled by Modular Binepine Ligands and Carbonate Bases

(2015) Philipp M. Holstein et al.   ACS Catalysis

Access to β-Lactams by Enantioselective Palladium(0)-Catalyzed C(sp3)H Alkylation

(2014) Julia Pedroni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile reactivity of Pd-catalysts: mechanistic features of the mono-N-protected amino acid ligand and cesium-halide base in Pd-catalyzed C–H bond functionalization

(2014) Djamaladdin G. Musaev et al.   CHEMICAL SOCIETY REVIEWS

Palladium(II)-Catalyzed Enantioselective C(sp3)–H Activation Using a Chiral Hydroxamic Acid Ligand

(2014) Kai-Jiong Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming the limitations of directed C–H functionalizations of heterocycles

(2014) Yue-Jin Liu et al.   NATURE

Synthesis of Ferrocene Derivatives with Planar Chirality via Palladium-Catalyzed Enantioselective C–H Bond Activation

(2014) Chao Pi et al.   ORGANIC LETTERS

Room-temperature enantioselective C–H iodination via kinetic resolution

(2014) Ling Chu et al.   SCIENCE

Pd(II)-Catalyzed Intermolecular Direct C–H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution

(2014) De-Wei Gao et al.   ACS Catalysis

Enantio- and Regioselective Intermolecular Benzylic and Allylic CH Bond Amination

(2013) Yota Nishioka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Developing Ligands for Palladium(II)-Catalyzed C–H Functionalization: Intimate Dialogue between Ligand and Substrate

(2013) Keary M. Engle et al.   JOURNAL OF ORGANIC CHEMISTRY

Scope and mechanism of asymmetric C(sp3)–H/C(Ar)–X coupling reactions: computational and experimental study

(2013) Evgeny Larionov et al.   Chemical Science

Chiral Monodentate Phosphines and Bulky Carboxylic Acids: Cooperative Effects in Palladium-Catalyzed Enantioselective C(sp3)-H Functionalization

(2012) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Enantioselective Intramolecular C(sp3)H Arylation for the Synthesis of Fused Cyclopentanes

(2012) Nicolas Martin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ligand-Enabled Methylene C(sp3)–H Bond Activation with a Pd(II) Catalyst

(2012) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activation of remote meta-C–H bonds assisted by an end-on template

(2012) Dasheng Leow et al.   NATURE

Cationic iridium-catalyzed enantioselective activation of secondary sp3 C–H bond adjacent to nitrogen atom

(2012) Shiguang Pan et al.   TETRAHEDRON

Asymmetric C(sp3)-H/C(Ar) coupling reactions. Highly enantio-enriched indolines via regiodivergent reaction of a racemic mixture

(2012) Dmitry Katayev et al.   Chemical Science

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of 2-methyl indolines by palladium catalysed asymmetric C(sp3)–H activation/cyclisation

(2011) Saithalavi Anas et al.   CHEMICAL COMMUNICATIONS

Ligand-Accelerated Cross-Coupling of C(sp2)–H Bonds with Arylboron Reagents

(2011) Keary M. Engle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes

(2011) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir(I)-Catalyzed Enantioselective Secondary sp3C–H Bond Activation of 2-(Alkylamino)pyridines with Alkenes

(2011) Shiguang Pan et al.   ORGANIC LETTERS

Development of biomimetic catalytic oxidation methods and non-salt methods using transition metal-based acid and base ambiphilic catalysts

(2011) Shun-Ichi MURAHASHI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Ligand-Accelerated C−H Activation Reactions: Evidence for a Switch of Mechanism

(2010) Keary M. Engle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Attractive noncovalent interactions in asymmetric catalysis: Links between enzymes and small molecule catalysts

(2010) R. R. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PdII-Catalyzed Enantioselective Activation of C(sp2)H and C(sp3)H Bonds Using Monoprotected Amino Acids as Chiral Ligands

(2008) Bing-Feng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Chiral Rhodium Carboxamidate Catalyst for Enantioselective C−H Amination

(2008) David N. Zalatan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY