Synthesis of Chiral β‐Lactams by Pd‐Catalyzed Enantioselective Amidation of Methylene C(sp 3 )–H Bonds

Pd(II)-Catalyzed Enantioselective Alkynylation of Unbiased Methylene C(sp3)–H Bonds Using 3,3′-Fluorinated-BINOL as a Chiral Ligand

(2019) Ye-Qiang Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Reactivity and Regioselectivity to Stereoselectivity: An Odyssey of Designing PIP Amine and Related Directing Groups for C—H Activation

(2019) Qi Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation

(2019) Hua-Rong Tong et al.   ACS Catalysis

Palladium(II)-Catalyzed Enantioselective Arylation of Unbiased Methylene C(sp3 )−H Bonds Enabled by a 2-Pyridinylisopropyl Auxiliary and Chiral Phosphoric Acids

(2018) Sheng-Yi Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlling Pd(iv) reductive elimination pathways enables Pd(ii)-catalysed enantioselective C(sp3)−H fluorination

(2018) Hojoon Park et al.   Nature Chemistry

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

Asymmetric Rh(II)/Pd(0) Relay Catalysis: Synthesis of α-Quaternary Chiral β-Lactams through Enantioselective C–H Insertion/Diastereoselective Allylation of Diazoamides

(2018) Liang-Zhu Huang et al.   ACS Catalysis

Assembling a Hybrid Pd Catalyst from a Chiral Anionic CoIII Complex and Ligand for Asymmetric C(sp3 )-H Functionalization

(2018) Hua-Jie Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(0)-Catalyzed Bidentate Auxiliary Directed Enantioselective Benzylic C–H Arylation of 3-Arylpropanamides Using the BINOL Phosphoramidite Ligand

(2018) Hua-Rong Tong et al.   ACS Catalysis

Antibacterial and β-Lactamase Inhibitory Activity of Monocyclic β-Lactams

(2017) Lena Decuyper et al.   MEDICINAL RESEARCH REVIEWS

Polycyclic Azetidines and Pyrrolidines via Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)–H Bonds

(2017) Jie Zhao et al.   ORGANIC LETTERS

Catalytic C–H amination at its limits: challenges and solutions

(2017) Damien Hazelard et al.   Organic Chemistry Frontiers

Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization

(2016) Gang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C−H Arylation of Amines Using a BINOL Phosphate Ligand

(2016) Hao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Enantioselective Synthesis of an 11-β-HSD-1 Inhibitor via an Asymmetric Methallylation Catalyzed by (S)-3,3′-F2-BINOL

(2016) Yongda Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides

(2016) Pankaj Jain et al.   Nature Chemistry

Functionalization of C(sp3)-H bonds using a transient directing group

(2016) F.-L. Zhang et al.   SCIENCE

Ligand-accelerated enantioselective methylene C(sp3)–H bond activation

(2016) Gang Chen et al.   SCIENCE

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids

(2015) Shao-Bai Yan et al.   ORGANIC LETTERS

Catalytic Enantioselective Ring-Opening and Ring-Closing Reactions of 3-Isothiocyanato Oxindoles and N-(2-Picolinoyl)aziridines

(2015) Linqing Wang et al.   ORGANIC LETTERS

Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes

(2015) Xinfang Xu et al.   Chemical Science

Access to β-Lactams by Enantioselective Palladium(0)-Catalyzed C(sp3)H Alkylation

(2014) Julia Pedroni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Synthesis of β-Lactams: Asymmetric Catalysis and Other Recent Advances

(2014) Cody Ross Pitts et al.   CHEMICAL REVIEWS

Recent Progress in the Synthesis of Functionalized β-Lactams through Transition-Metal-Catalyzed C(sp3)–H Amidation

(2014) Bing-Feng Shi et al.   SYNLETT

Stereoselective Synthesis of Chiral α-Amino-β-Lactams through Palladium(II)-Catalyzed Sequential Monoarylation/Amidation of C(sp3)H Bonds

(2013) Qi Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Unactivated C(sp3)–H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-Lactams

(2013) Wen-Wu Sun et al.   ORGANIC LETTERS

Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′-F2-BINOL

(2013) Yongda Zhang et al.   ORGANIC LETTERS

Recent development of direct asymmetric functionalization of inert C–H bonds

(2013) Chao Zheng et al.   RSC Advances

Metal-Catalyzed Nitrogen-Atom Transfer Methods for the Oxidation of Aliphatic C–H Bonds

(2012) Jennifer L. Roizen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Intramolecular CH Insertion of α-Diazoacetamides in Water by Dirhodium(II) Catalysts Derived from Natural Amino Acids

(2012) Nuno R. Candeias et al.   ADVANCED SYNTHESIS & CATALYSIS

Advances in the chemistry of ?-lactam and its medicinal applications

(2012) Anushree Kamath et al.   TETRAHEDRON

Catalytic C–H amination: the stereoselectivity issue

(2011) Florence Collet et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE