标题
Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance
作者
关键词
-
出版物
Frontiers in Immunology
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-05-17
DOI
10.3389/fimmu.2021.657293
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Living with Yourself: Innate Lymphoid Cell Immunometabolism
- (2020) Marion Rolot et al. Cells
- Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells
- (2020) Jin Gong et al. Cell Death & Disease
- Sex-associated molecular differences for cancer immunotherapy
- (2020) Youqiong Ye et al. Nature Communications
- IL-15 in the Combination Immunotherapy of Cancer
- (2020) Thomas A. Waldmann et al. Frontiers in Immunology
- Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
- (2020) Teresa Manzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism
- (2020) Sarthak Gupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A decade of immune-checkpoint inhibitors in cancer therapy
- (2020) Caroline Robert Nature Communications
- Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer
- (2020) Lisa M. Becker et al. Cell Reports
- Analysis of Human Natural Killer Cell Metabolism
- (2020) Javier Traba et al. Jove-Journal of Visualized Experiments
- Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
- (2020) Alison E. Ringel et al. CELL
- NAD+ metabolism and its roles in cellular processes during ageing
- (2020) Anthony J. Covarrubias et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches
- (2020) Sahar Aghakhani et al. Cancers
- Malonylation of GAPDH is an inflammatory signal in macrophages
- (2019) Silvia Galván-Peña et al. Nature Communications
- A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
- (2019) Alessio Cortellini et al. Journal for ImmunoTherapy of Cancer
- Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer
- (2019) Rongsheng Zhang et al. Cell Death & Disease
- Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD-1 Therapy
- (2019) Yu-Xue Zhang et al. NANO LETTERS
- The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc
- (2019) Han Dong et al. NATURE IMMUNOLOGY
- Targeting Tumor-Associated Macrophages in Cancer
- (2019) Paulina Pathria et al. TRENDS IN IMMUNOLOGY
- Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics
- (2019) William J. Turbitt et al. Frontiers in Immunology
- Obesity and Breast Cancer: Role of Leptin
- (2019) Flora Sánchez-Jiménez et al. Frontiers in Oncology
- Neutrophil Heterogeneity in Cancer: From Biology to Therapies
- (2019) Pacôme Lecot et al. Frontiers in Immunology
- Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
- (2019) Stefano Angiari et al. Cell Metabolism
- Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance
- (2019) Xiaohu Zheng et al. NATURE IMMUNOLOGY
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
- (2019) Robert D. Leone et al. SCIENCE
- Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
- (2019) Kathrin Renner et al. Cell Reports
- Monalizumab: inhibiting the novel immune checkpoint NKG2A
- (2019) Thorbald van Hall et al. Journal for ImmunoTherapy of Cancer
- Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase
- (2019) Mario A. Lauterbach et al. IMMUNITY
- Alterations in composition of immune cells and impairment of anti-tumor immune response in aged oral cancer-bearing mice
- (2019) Katsuhisa Sekido et al. ORAL ONCOLOGY
- Metabolic Pathways Involved in Regulatory T Cell Functionality
- (2019) Rosalie W. M. Kempkes et al. Frontiers in Immunology
- Association Between Body Mass Index and Overall Survival With Immune Checkpoint Inhibitor Therapy for Advanced Non–Small Cell Lung Cancer
- (2019) Ganessan Kichenadasse et al. JAMA Oncology
- Targeting Glutamine Metabolism for Cancer Treatment
- (2018) Yeon-Kyung Choi et al. Biomolecules & Therapeutics
- Cancer, obesity and immunometabolism – Connecting the dots
- (2018) Lydia Dyck et al. CANCER LETTERS
- Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer
- (2018) Xianmin Mu et al. CELL CYCLE
- Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression
- (2018) Jingjing Cong et al. Cell Metabolism
- Nutritional shortage augments cisplatin-effects on murine melanoma cells
- (2018) F. Antunes et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Obesity induced T cell dysfunction and implications for cancer immunotherapy
- (2018) Ethan G Aguilar et al. CURRENT OPINION IN IMMUNOLOGY
- Control of mitochondrial superoxide production by reverse electron transport at complex I
- (2018) Ellen L. Robb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism
- (2018) Vanessa Zaiatz-Bittencourt et al. JOURNAL OF IMMUNOLOGY
- Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme
- (2018) Todd A Triplett et al. NATURE BIOTECHNOLOGY
- Second signals rescue B cells from activation-induced mitochondrial dysfunction and death
- (2018) Munir Akkaya et al. NATURE IMMUNOLOGY
- Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
- (2018) Róisín M. Loftus et al. Nature Communications
- Programmed Cell Death Ligand 1 (PD-L1) Signaling Regulates Macrophage Proliferation and Activation
- (2018) Genevieve P Hartley et al. Cancer Immunology Research
- Teaching an old dog new tricks: next-generation CAR T cells
- (2018) Nicholas Tokarew et al. BRITISH JOURNAL OF CANCER
- Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell Activation
- (2018) Billur Akkaya et al. JOURNAL OF IMMUNOLOGY
- Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
- (2018) Xavier Michelet et al. NATURE IMMUNOLOGY
- Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
- (2018) Fangjie Wang et al. Nature Communications
- Lactate-mediated acidification of tumor microenvironment induces apoptosis of liver-resident NK cells in colorectal liver metastasis
- (2018) Cathal Harmon et al. Cancer Immunology Research
- Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
- (2018) Monica Parodi et al. Frontiers in Immunology
- Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies
- (2017) Johann Pötzl et al. INTERNATIONAL JOURNAL OF CANCER
- PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
- (2017) Sydney R. Gordon et al. NATURE
- Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
- (2017) W. K. Eddie Ip et al. SCIENCE
- Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages
- (2017) Pengfei Sun et al. Oncotarget
- Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
- (2017) Erika M. Palmieri et al. Cell Reports
- ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells
- (2017) Hongsheng Wang et al. Scientific Reports
- Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
- (2016) Federico Pietrocola et al. CANCER CELL
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
- (2016) Lifeng Yang et al. Cell Metabolism
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- GAPDH Binding to TNF-α mRNA Contributes to Posttranscriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism
- (2016) Patrick Millet et al. JOURNAL OF IMMUNOLOGY
- Metabolic Reprogramming Supports IFN-γ Production by CD56brightNK Cells
- (2016) Sinéad E. Keating et al. JOURNAL OF IMMUNOLOGY
- CAFs and TAMs: maestros of the tumour microenvironment
- (2016) Yoshihiro Komohara et al. JOURNAL OF PATHOLOGY
- PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells
- (2016) Dante Miranda et al. MEDIATORS OF INFLAMMATION
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
- (2016) M. Peng et al. SCIENCE
- TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
- (2016) Sébastien Viel et al. Science Signaling
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Repression of GSK3 restores NK cell cytotoxicity in AML patients
- (2016) Reshmi Parameswaran et al. Nature Communications
- Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity
- (2016) Shimin Wang et al. Scientific Reports
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
- (2016) Anthony J Covarrubias et al. eLife
- TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
- (2016) Sébastien Viel et al. Science Signaling
- A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
- (2016) Akio Ohta Frontiers in Immunology
- Fasting and cancer treatment in humans: A case series report
- (2016) Fernando M. Safdie et al. Aging-US
- Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner
- (2016) Agustina Errea et al. PLoS One
- Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma
- (2016) Hao Liu et al. Scientific Reports
- Natural Killer Cell Adoptive Transfer Therapy
- (2015) Zachary B. Davis et al. CANCER JOURNAL
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo
- (2015) Julianna Blagih et al. IMMUNITY
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- The 3 major types of innate and adaptive cell-mediated effector immunity
- (2015) Francesco Annunziato et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- High Mitochondrial Respiration and Glycolytic Capacity Represent a Metabolic Phenotype of Human Tolerogenic Dendritic Cells
- (2015) Frano Malinarich et al. JOURNAL OF IMMUNOLOGY
- Activation-Specific Metabolic Requirements for NK Cell IFN-γ Production
- (2015) Molly P. Keppel et al. JOURNAL OF IMMUNOLOGY
- Pyruvate Dehydrogenase Kinase 1 Participates in Macrophage Polarization via Regulating Glucose Metabolism
- (2015) Zheng Tan et al. JOURNAL OF IMMUNOLOGY
- Development and function of tissue resident macrophages in mice
- (2015) Katrin Kierdorf et al. SEMINARS IN IMMUNOLOGY
- Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages
- (2015) Ling Ding et al. Oncotarget
- Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
- (2015) Giovanna Bianchi et al. Oncotarget
- IL-2: The First Effective Immunotherapy for Human Cancer
- (2014) S. A. Rosenberg JOURNAL OF IMMUNOLOGY
- mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
- (2014) Raymond P. Donnelly et al. JOURNAL OF IMMUNOLOGY
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
- (2014) Antoine Marçais et al. NATURE IMMUNOLOGY
- Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
- (2013) Connie Jackaman et al. AGING CELL
- Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition
- (2013) Eric O. Long et al. Annual Review of Immunology
- Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
- (2013) D. Laoui et al. CANCER RESEARCH
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC
- (2013) Mirna Balsamo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mitochondrial ROS Fire Up T Cell Activation
- (2013) Michael P. Murphy et al. IMMUNITY
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
- (2013) G Comito et al. ONCOGENE
- SeXX matters in immunity
- (2013) J.G. Markle et al. TRENDS IN IMMUNOLOGY
- Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
- (2012) B. Everts et al. BLOOD
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- Suppression, subversion and escape: the role of regulatory T cells in cancer progression
- (2012) K. Oleinika et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan
- (2012) Richard Metz et al. OncoImmunology
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy
- (2011) Takami Sato et al. IMMUNOLOGIC RESEARCH
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
- (2011) Christiane A. Opitz et al. NATURE
- Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
- (2010) X. Liu et al. BLOOD
- Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index
- (2010) C. Lee et al. CANCER RESEARCH
- An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
- (2010) J. D. Mezrich et al. JOURNAL OF IMMUNOLOGY
- Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation
- (2010) E. L. Carr et al. JOURNAL OF IMMUNOLOGY
- Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection
- (2010) Dimitra Peppa et al. PLoS Pathogens
- The tumor suppressor function of mitochondria: Translation into the clinics
- (2009) José M. Cuezva et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
- (2009) M. D. Sharma et al. BLOOD
- Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry
- (2009) A. Hirayama et al. CANCER RESEARCH
- Human natural killer cells
- (2008) M. A. Caligiuri BLOOD
- Glucose avidity of carcinomas
- (2008) Álvaro D. Ortega et al. CANCER LETTERS
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tumor-derived TGF-β Mediates Conversion of CD4+Foxp3+ Regulatory T Cells in a Murine Model of Pancreas Cancer
- (2008) Tricia A. Moo-Young et al. JOURNAL OF IMMUNOTHERAPY
- Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
- (2008) L. Raffaghello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started