The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
出版年份 2014 全文链接
标题
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
作者
关键词
-
出版物
NATURE IMMUNOLOGY
Volume 15, Issue 8, Pages 749-757
出版商
Springer Nature
发表日期
2014-06-30
DOI
10.1038/ni.2936
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Metabolic Pathways in Immune Cell Activation and Quiescence
- (2013) Erika L. Pearce et al. IMMUNITY
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection
- (2012) Thomas Baranek et al. Cell Host & Microbe
- The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation
- (2012) Scott M. Gordon et al. IMMUNITY
- PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells
- (2012) David K. Finlay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NK Cell Maturation and Function in C57BL/6 Mice Are Altered by Caloric Restriction
- (2012) J. F. Clinthorne et al. JOURNAL OF IMMUNOLOGY
- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
- (2011) Brian Magnuson et al. BIOCHEMICAL JOURNAL
- Different NK Cell Developmental Events Require Different Levels of IL-15 Trans-Presentation
- (2011) G. A. Lee et al. JOURNAL OF IMMUNOLOGY
- Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor
- (2011) E. Narni-Mancinelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development
- (2010) E. Eckelhart et al. BLOOD
- Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways
- (2010) Keunwook Lee et al. IMMUNITY
- Implications for Gene Therapy-Limiting Expression of IL-2R c Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance
- (2010) S. J. Orr et al. JOURNAL OF IMMUNOLOGY
- Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
- (2010) T. W. Hand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
- (2009) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Maturation of mouse NK cells is a 4-stage developmental program
- (2009) L. Chiossone et al. BLOOD
- Macrophage- and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets
- (2009) Erwan Mortier et al. IMMUNITY
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
- (2009) Greg M. Delgoffe et al. IMMUNITY
- Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
- (2009) Valérie Risson et al. JOURNAL OF CELL BIOLOGY
- MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells
- (2009) R. J. Salmond et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: IL-15-Independent NK Cell Response to Mouse Cytomegalovirus Infection
- (2009) J. C. Sun et al. JOURNAL OF IMMUNOLOGY
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
- Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense
- (2008) Naoko Satoh-Takayama et al. IMMUNITY
- The p110δ of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation
- (2008) Hailong Guo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In vivo expression of signaling proteins in reconstituted NK cells
- (2008) Selinda J. Orr et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin
- (2008) Carmelo Luci et al. NATURE IMMUNOLOGY
- RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells
- (2008) Stephanie L Sanos et al. NATURE IMMUNOLOGY
- Functions of natural killer cells
- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
- Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
- (2008) Linda V Sinclair et al. NATURE IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now