Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class
出版年份 2021 全文链接
标题
Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class
作者
关键词
COVID-19, multi-donor antibody class, neutralizing antibody, quaternary recognition, RBD, SARS-CoV-2, spike
出版物
Cell Reports
Volume 35, Issue 1, Pages 108950
出版商
Elsevier BV
发表日期
2021-03-20
DOI
10.1016/j.celrep.2021.108950
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- An interactive web-based dashboard to track COVID-19 in real time
- (2020) Ensheng Dong et al. LANCET INFECTIOUS DISEASES
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
- (2020) Qihui Wang et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
- (2020) Rui Shi et al. NATURE
- Human neutralizing antibodies elicited by SARS-CoV-2 infection
- (2020) Bin Ju et al. NATURE
- Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
- (2020) Dora Pinto et al. NATURE
- A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
- (2020) Yan Wu et al. SCIENCE
- Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients
- (2020) Christoph Kreer et al. CELL
- Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
- (2020) Christopher O. Barnes et al. CELL
- Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells
- (2020) Yunlong Cao et al. CELL
- Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
- (2020) Jiandong Huo et al. Cell Host & Microbe
- Convergent antibody responses to SARS-CoV-2 in convalescent individuals
- (2020) Davide F. Robbiani et al. NATURE
- Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
- (2020) Lihong Liu et al. NATURE
- Potently neutralizing and protective human antibodies against SARS-CoV-2
- (2020) Seth J. Zost et al. NATURE
- Controlling the SARS-CoV-2 spike glycoprotein conformation
- (2020) Rory Henderson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A thermostable, closed SARS-CoV-2 spike protein trimer
- (2020) Xiaoli Xiong et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation
- (2020) Matthew McCallum et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects
- (2020) Antoni G. Wrobel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
- (2020) Thomas F. Rogers et al. SCIENCE
- Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
- (2020) Johanna Hansen et al. SCIENCE
- Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
- (2020) Zhe Lv et al. SCIENCE
- Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
- (2020) Philip J. M. Brouwer et al. SCIENCE
- Structural basis of a shared antibody response to SARS-CoV-2
- (2020) Meng Yuan et al. SCIENCE
- A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
- (2020) Jakob Kreye et al. CELL
- Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy
- (2020) Shuo Du et al. CELL
- SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
- (2020) Christopher O. Barnes et al. NATURE
- Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
- (2020) Sandhya Bangaru et al. SCIENCE
- Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
- (2020) Christine Toelzer et al. SCIENCE
- Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
- (2020) M. Alejandra Tortorici et al. SCIENCE
- An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain
- (2020) Nicholas C. Wu et al. Cell Reports
- Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection
- (2020) Hangping Yao et al. CELL RESEARCH
- Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
- (2020) Hejun Liu et al. IMMUNITY
- SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19
- (2020) Peter Chen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis
- (2020) Natalia G. Herrera et al. ACS Omega
- Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV
- (2019) Stefanie A. Ehrhardt et al. NATURE MEDICINE
- HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
- (2018) Peter D. Kwong et al. IMMUNITY
- Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope
- (2018) Katharina Imkeller et al. SCIENCE
- ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps
- (2018) Tristan Ian Croll Acta Crystallographica Section D-Structural Biology
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Clustal Omega for making accurate alignments of many protein sequences
- (2017) Fabian Sievers et al. PROTEIN SCIENCE
- Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses
- (2016) M. Gordon Joyce et al. CELL
- Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes
- (2016) Nicole L. Kallewaard et al. CELL
- ABodyBuilder: Automated antibody structure prediction with data–driven accuracy estimation
- (2016) Jinwoo Leem et al. mAbs
- SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts
- (2016) Chaim A. Schramm et al. Frontiers in Immunology
- Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
- (2015) Tongqing Zhou et al. CELL
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- Rapid development of broadly influenza neutralizing antibodies through redundant mutations
- (2014) Leontios Pappas et al. NATURE
- Antibody structure determination using a combination of homology modeling, energy-based refinement, and loop prediction
- (2014) Kai Zhu et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- ThePDB_REDOserver for macromolecular structure model optimization
- (2014) Robbie P. Joosten et al. IUCrJ
- Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
- (2013) Tongqing Zhou et al. IMMUNITY
- IgBLAST: an immunoglobulin variable domain sequence analysis tool
- (2013) Jian Ye et al. NUCLEIC ACIDS RESEARCH
- Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
- (2013) J. Jardine et al. SCIENCE
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies
- (2012) Peter D. Kwong et al. IMMUNITY
- B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
- (2012) Barton F Haynes et al. NATURE BIOTECHNOLOGY
- Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody
- (2012) A. G. Schmidt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Integration, scaling, space-group assignment and post-refinement
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
- (2008) X. Brochet et al. NUCLEIC ACIDS RESEARCH
- IMGT(R), the international ImMunoGeneTics information system(R)
- (2008) M.-P. Lefranc et al. NUCLEIC ACIDS RESEARCH
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