标题
Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice
作者
关键词
-
出版物
Science Translational Medicine
Volume 13, Issue 584, Pages eaay9056
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-03-11
DOI
10.1126/scitranslmed.aay9056
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Defining the Functional Role of NaV1.7 in Human Nociception
- (2019) Lucy A. McDermott et al. NEURON
- Liver-directed gene therapy results in long term correction of progressive familial intrahepatic cholestasis type 3 in mice
- (2019) Sem J. Aronson et al. JOURNAL OF HEPATOLOGY
- Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF induced pain
- (2019) Fan Zhang et al. JOURNAL OF NEUROSCIENCE
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Enhancing gene editing specificity by attenuating DNA cleavage kinetics
- (2019) Jeffrey C. Miller et al. NATURE BIOTECHNOLOGY
- The Genetics of Neuropathic Pain from Model Organisms to Clinical Application
- (2019) Margarita Calvo et al. NEURON
- In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation
- (2018) Ana M. Moreno et al. MOLECULAR THERAPY
- Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain
- (2018) Apoorva Mohan et al. PAIN
- Na V 1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine
- (2018) Yang Yang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
- (2018) Pratiksha I. Thakore et al. Nature Communications
- RTF: a rapid and versatile tissue optical clearing method
- (2018) Tingting Yu et al. Scientific Reports
- α-(phenylselanyl) acetophenone abolishes acute restraint stress induced-comorbid pain, depression and anxiety-related behaviors in mice
- (2018) Fernanda Severo Sabedra Sousa et al. NEUROCHEMISTRY INTERNATIONAL
- The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons
- (2018) Tânia C. Gonçalves et al. Frontiers in Pharmacology
- Ion channels as therapeutic antibody targets
- (2018) Catherine J. Hutchings et al. mAbs
- MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats
- (2018) Weihua Cai et al. Scientific Reports
- Characterization of small fiber pathology in a mouse model of Fabry disease
- (2018) Lukas Hofmann et al. eLife
- AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials
- (2017) Nathan Hardcastle et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain
- (2017) Temugin Berta et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse
- (2017) Wisam Toma et al. NEUROPHARMACOLOGY
- Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice
- (2017) Jörg Isensee et al. Science Signaling
- Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel
- (2017) Wonseok Chang et al. Neuroscience Bulletin
- Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice
- (2017) Jörg Isensee et al. Science Signaling
- Long-Term Assessment of AAV-Mediated Zinc Finger Nuclease Expression in the Mouse Brain
- (2017) Muzna Zahur et al. Frontiers in Molecular Neuroscience
- Neuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in mice
- (2017) Frances M. Munoz et al. Scientific Reports
- Effects of intraplantar botulinum toxin-B on carrageenan-induced changes in nociception and spinal phosphorylation of GluA1 and Akt
- (2016) Shafaq Sikandar et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Managing Chronic Pain in Special Populations with Emphasis on Pediatric, Geriatric, and Drug Abuser Populations
- (2016) Kyle M. Baumbauer et al. MEDICAL CLINICS OF NORTH AMERICA
- MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat
- (2016) Jinping Shao et al. Molecular Pain
- Sodium channel Nav1.8
- (2016) Chongyang Han et al. NEUROLOGY
- Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
- (2016) Max A Horlbeck et al. eLife
- Unknown
- (2015) Andrew Tan et al. MOLECULAR MEDICINE
- Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
- (2015) Pratiksha I Thakore et al. NATURE METHODS
- MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice
- (2015) Enza Palazzo et al. PAIN
- Effect of down—regulation of voltage—gated sodium channel Nav1.7 on activation of astrocytes and microglia in DRG in rats with cancer pain
- (2015) Jun Pan et al. Asian Pacific Journal of Tropical Medicine
- Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7
- (2015) Michael S. Minett et al. Nature Communications
- shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury
- (2015) Weihua Cai et al. BMC Anesthesiology
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- Painful and painless channelopathies
- (2014) David L H Bennett et al. LANCET NEUROLOGY
- Optimization of a Cisplatin Model of Chemotherapy-Induced Peripheral Neuropathy in Mice: Use of Vitamin C and Sodium Bicarbonate Pretreatments to Reduce Nephrotoxicity and Improve Animal Health Status
- (2014) Josée Guindon et al. Molecular Pain
- Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse
- (2014) Daniel J. Schuster et al. Frontiers in Neuroanatomy
- Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna
- (2014) Christian Hinderer et al. Molecular Therapy-Methods & Clinical Development
- Opioids for Chronic Pain: New Evidence, New Strategies, Safe Prescribing
- (2013) Oscar A. de Leon-Casasola AMERICAN JOURNAL OF MEDICINE
- KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
- (2013) Angelo Lupo et al. CURRENT GENOMICS
- Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates
- (2013) S J Gray et al. GENE THERAPY
- Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy
- (2013) Virginia Haurigot et al. JOURNAL OF CLINICAL INVESTIGATION
- An Overview of Animal Models of Pain: Disease Models and Outcome Measures
- (2013) Nicholas S. Gregory et al. JOURNAL OF PAIN
- AAV9-mediated Expression of a Non-self Protein in Nonhuman Primate Central Nervous System Triggers Widespread Neuroinflammation Driven by Antigen-presenting Cell Transduction
- (2013) Lluis Samaranch et al. MOLECULAR THERAPY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Sodium Channel Nav1.7 Is Essential for Lowering Heat Pain Threshold after Burn Injury
- (2012) S. D. Shields et al. JOURNAL OF NEUROSCIENCE
- Virus-mediated shRNA Knockdown of Nav1.3 in Rat Dorsal Root Ganglion Attenuates Nerve Injury-induced Neuropathic Pain
- (2012) Omar A Samad et al. MOLECULAR THERAPY
- In Vivo Gene Knockdown in Rat Dorsal Root Ganglia Mediated by Self-Complementary Adeno-Associated Virus Serotype 5 Following Intrathecal Delivery
- (2012) Qinghao Xu et al. PLoS One
- Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice
- (2011) Sara Jane Ward et al. ANESTHESIA AND ANALGESIA
- Novel object exploration in mice: Not all objects are created equal
- (2011) Charles J. Heyser et al. BEHAVIOURAL PROCESSES
- Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
- (2011) Jan Weiss et al. NATURE
- The Prevalence of Chronic Pain in United States Adults: Results of an Internet-Based Survey
- (2010) Catherine B. Johannes et al. JOURNAL OF PAIN
- Differential Adeno-Associated Virus Mediated Gene Transfer to Sensory Neurons following Intrathecal Delivery by Direct Lumbar Puncture
- (2010) Lucy Vulchanova et al. Molecular Pain
- Pain perception is altered by a nucleotide polymorphism in SCN9A
- (2010) F. Reimann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular and Molecular Mechanisms of Pain
- (2009) Allan I. Basbaum et al. CELL
- Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
- (2009) H. J. Kim et al. GENOME RESEARCH
- Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety
- (2009) Alexia Thomas et al. PSYCHOPHARMACOLOGY
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