标题
Raf promotes dimerization of the Ras G-domain with increased allosteric connections
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 118, Issue 10, Pages e2015648118
出版商
Proceedings of the National Academy of Sciences
发表日期
2021-03-03
DOI
10.1073/pnas.2015648118
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling
- (2020) Serena Muratcioglu et al. JOURNAL OF MOLECULAR BIOLOGY
- Two Distinct Structures of Membrane‐Associated Homodimers of GTP‐ and GDP‐Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement
- (2020) Ki‐Young Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane
- (2020) Que N. Van et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events
- (2019) Jenny J. Y. Lin et al. Science Signaling
- TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps
- (2019) Jason Yi et al. Nature Communications
- A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
- (2019) William Y. C. Huang et al. SCIENCE
- Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes
- (2019) Eric Barklis et al. JOURNAL OF MOLECULAR BIOLOGY
- Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
- (2019) Daniel P. Donnelly et al. NATURE METHODS
- Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases
- (2019) Yasushi Kondo et al. SCIENCE
- Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes
- (2019) Eunyoung Park et al. NATURE
- High-throughput, single-particle tracking reveals nested membrane domains that dictate KRasG12D diffusion and trafficking
- (2019) Yerim Lee et al. eLife
- K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions
- (2018) Jean K. Chung et al. BIOPHYSICAL JOURNAL
- KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
- (2018) Chiara Ambrogio et al. CELL
- K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D
- (2018) Jillian A. Parker et al. STRUCTURE
- A “Tug of War” Maintains a Dynamic Protein–Membrane Complex: Molecular Dynamics Simulations of C-Raf RBD-CRD Bound to K-Ras4B at an Anionic Membrane
- (2018) Zhen-Lu Li et al. ACS Central Science
- The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects
- (2017) Christian W. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Spatiotemporal Analysis of K-Ras Plasma Membrane Interactions Reveals Multiple High Order Homo-oligomeric Complexes
- (2017) Suparna Sarkar-Banerjee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- TrackMate: An open and extensible platform for single-particle tracking
- (2017) Jean-Yves Tinevez et al. METHODS
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate
- (2017) Young Kwang Lee et al. Nature Communications
- Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers
- (2017) Priyanka Prakash et al. Scientific Reports
- ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions
- (2017) D. Franke et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Computational Equilibrium Thermodynamic and Kinetic Analysis of K-Ras Dimerization through an Effector Binding Surface Suggests Limited Functional Role
- (2016) Abdallah Sayyed-Ahmad et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Covalent Ras Dimerization on Membrane Surfaces through Photosensitized Oxidation
- (2016) Jean K. Chung et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inhibition of RAS function through targeting an allosteric regulatory site
- (2016) Russell Spencer-Smith et al. Nature Chemical Biology
- CHARMM36m: an improved force field for folded and intrinsically disordered proteins
- (2016) Jing Huang et al. NATURE METHODS
- One-way membrane trafficking of SOS in receptor-triggered Ras activation
- (2016) Sune M Christensen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles
- (2016) Dina Schneidman-Duhovny et al. NUCLEIC ACIDS RESEARCH
- Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
- (2016) William Y. C. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase separation of signaling molecules promotes T cell receptor signal transduction
- (2016) Xiaolei Su et al. SCIENCE
- One-way membrane trafficking of SOS in receptor-triggered Ras activation
- (2016) Sune M Christensen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering
- (2016) Olga Blaževitš et al. Scientific Reports
- The Ras G Domain Lacks the Intrinsic Propensity to Form Dimers
- (2015) Elizaveta A. Kovrigina et al. BIOPHYSICAL JOURNAL
- Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway
- (2015) Xiaolin Nan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential dynamics of RAS isoforms in GDP- and GTP-bound states
- (2015) Abhijeet Kapoor et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS
- (2015) James M. Aramini et al. STRUCTURE
- GTP-Dependent K-Ras Dimerization
- (2015) Serena Muratcioglu et al. STRUCTURE
- Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD
- (2015) Susan K. Fetics et al. STRUCTURE
- Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions
- (2015) William K. Gillette et al. Scientific Reports
- Upgrade of MacCHESS facility for X-ray scattering of biological macromolecules in solution
- (2015) Alvin Samuel Acerbo et al. JOURNAL OF SYNCHROTRON RADIATION
- Quantifying Protein-Protein Interactions of Peripheral Membrane Proteins by Fluorescence Brightness Analysis
- (2014) Elizabeth M. Smith et al. BIOPHYSICAL JOURNAL
- The Efficacy of Raf Kinase Recruitment to the GTPase H-ras Depends on H-ras Membrane Conformer-specific Nanoclustering
- (2014) Camilo Guzmán et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- H-Ras forms dimers on membrane surfaces via a protein-protein interface
- (2014) W.-C. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
- (2014) L. Iversen et al. SCIENCE
- Rotational and Translational Dynamics of Ras Proteins upon Binding to Model Membrane Systems
- (2013) Alexander Werkmüller et al. CHEMPHYSCHEM
- Signal Integration by Lipid-Mediated Spatial Cross Talk between Ras Nanoclusters
- (2013) Yong Zhou et al. MOLECULAR AND CELLULAR BIOLOGY
- Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition
- (2012) Genevieve Holzapfel et al. BIOCHEMISTRY
- N-Ras Forms Dimers at POPC Membranes
- (2012) Jörn Güldenhaupt et al. BIOPHYSICAL JOURNAL
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- New developments in theATSASprogram package for small-angle scattering data analysis
- (2012) Maxim V. Petoukhov et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Mechanisms of Ras membrane organization and signaling: Ras on a rocker
- (2011) Daniel Abankwa et al. CELL CYCLE
- UCSF Chimera, MODELLER, and IMP: An integrated modeling system
- (2011) Zheng Yang et al. JOURNAL OF STRUCTURAL BIOLOGY
- Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
- (2011) M. C. Good et al. SCIENCE
- Ras trafficking, localization and compartmentalized signalling
- (2011) Ian A. Prior et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Allosteric modulation of Ras positions Q61 for a direct role in catalysis
- (2010) G. Buhrman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamical networks in tRNA:protein complexes
- (2009) A. Sethi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prediction of Protein–Protein Interaction Sites in Sequences and 3D Structures by Random Forests
- (2009) Mile Šikić et al. PLoS Computational Biology
- Mapping the Nucleotide and Isoform-Dependent Structural and Dynamical Features of Ras Proteins
- (2008) Alemayehu A. Gorfe et al. STRUCTURE
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