Article
Chemistry, Applied
Zheng Jin, Gaowei Hu, Kai Zhao
Summary: This study demonstrated that the synthesized M-N-2-HACC/N-CMCS nanoparticles showed high efficiency in mucosal delivery by utilizing the interaction with mucosal sites for drug release and delivery.
CARBOHYDRATE POLYMERS
(2022)
Article
Food Science & Technology
Ozi Adi Saputra, Wahyu Nur Safitriono, Dyah Ellyawati Kusumaningtyas Maharani, Amalia Febiana, Fajar Rakhman Wibowo
Summary: This study aims to overcome the limitations of curcumin by formulating a nano-emulsion called curcumin emulsion (CE) and encapsulating it within chitosan-assembled mesoporous silica nanoparticles (Chi@SiO2@CE). The CE exhibited strong antioxidant activity compared to curcumin alone, and the Chi@SiO2@CE showed pH-controlled release behavior, indicating potential as a pH-responsive drug delivery material.
Article
Biochemistry & Molecular Biology
Theodore Ebenezer Leonard, Alvaro Filbert Liko, Marsia Gustiananda, Agus Budiawan Naro Putra, Ario Betha Juanssilfero, Pietradewi Hartrianti
Summary: Mucoadhesive drug delivery systems (DDS) can enhance localized drug distribution and retention, promoting safer chemotherapy for colorectal cancer (CRC). Carbohydrate polymers, such as pectin (P) and chitosan (CS), are potential biomaterials for CRC-targeted DDS due to their gelling ability, mucoadhesive property, colonic digestibility, and anticancer activity. Thiolation can augment polymer mucoadhesion, while the P-CS polyelectrolyte complex improves structural stability. TP-CS composites show superior mucoadhesive properties compared to single- or dual-crosslinked counterparts, making them promising biomaterials for CRC-targeted DDS.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Dan Xu, Tiantian Jin, Lijun Song, Ning Zhu, Limin Han, Hailong Hong
Summary: The construction of controlled release for drugs is a promising strategy in disease treatment, which can improve the bioavailability of utilized drugs and reduce the side effects. A simple and green strategy was developed to prepare stable amorphous calcium carbonate (ACC) using polyvinyl pyrrolidone (PVP) as stabilizer. The obtained ACC-PVP exhibited high drug loading efficiency and pH responsive release properties for anticancer drugs 5-Fluorouracil (5-FU) and curcumin (CUR) in phosphate buffer solution and simulated gastric juice.
Article
Biochemistry & Molecular Biology
Richard Wibel, Doris E. Braun, Laurenz Haemmerle, Arne M. Joergensen, Patrick Knoll, Willi Salvenmoser, Christian Steinbring, Andreas Bernkop-Schnuerch
Summary: In this study, thiolated chitosan was used as a coating material for solid lipid nanoparticles, with the protection of thiol groups playing a key role in their interaction with mucosa. Different coating materials showed varying effects on mucus interaction and diffusion behavior on intestinal mucosa.
Article
Biotechnology & Applied Microbiology
Yasaman Hashtrodylar, Shahram Rabbani, Simin Dadashzadeh, Azadeh Haeri
Summary: This study developed nanoaggregates of berberine-phospholipid complex incorporated into thiolated chitosan (TCS) hydrogel for the treatment of aphthous stomatitis. The nanoaggregates-TCS exhibited prolonged release of berberine and increased mucoadhesive strength compared with CS hydrogel. The in vivo studies revealed the superior therapeutic efficacy of nanoaggregates-TCS.
Review
Chemistry, Applied
Xiaoyang Liu, Yuxuan Wu, Xinchen Zhao, Zhengke Wang
Summary: Organic-inorganic hybrid materials, such as chitosan-based hybrids, exhibit outstanding performance due to the synergy of their components. Chitosan is a commonly used organic material in bionic hybrids, and techniques like hybridization are favored for their convenience and efficiency in tailoring the material for various applications. Despite the progress made in bioactive chitosan-based hybrid materials, challenges and specific directions for future development are still proposed.
CARBOHYDRATE POLYMERS
(2021)
Article
Biotechnology & Applied Microbiology
Ming Sun, Lidi Cheng, Zexian Xu, Liqiang Chen, Yanshan Liu, Yaoxiang Xu, Dongyang Zhou, Xiuxiu Zhang, Qihui Zhou, Jian Sun
Summary: This study aims to explore the potential feasibility of a novel temperature-sensitive hydrogel-based dual sustained-release system for the repair and treatment of infectious jaw defects. The results indicate that the system shows outstanding sustained-release ability, biocompatibility, and antibacterial properties. This study provides new insights for the treatment of infectious jaw defects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Asif Javaid, Sobia Jabeen, Noureen Arshad, Khalid Mahmood Zia, Muhammad Tahir Hussain, Inam Ullah, Saliha Ahmad, Muhammad Shoaib
Summary: In this study, chitosan and amylopectin blends were used to engineer poly-urethanes for sustained drug release systems. The synthesis of polyurethanes was monitored using spectroscopic techniques and the molecular weights of the prepared polymers were measured. The thermal degradation behavior of the samples was also recorded. Polyurethane prepared with equimolar blends of chitosan and amylopectin showed minimum release of the drug compared to pristine chitosan and amylopectin based poly-urethanes.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Pharmacology & Pharmacy
Yang Gao, Qingming Ma, Jie Cao, Yiwen Wang, Xin Yang, Qiulong Xu, Qing Liang, Yong Sun
Summary: The review highlights the recent progress in fabricating chitosan-based biomaterials using microfluidic technology, emphasizing the precise control over morphology and microstructures, as well as the potential applications of chitosan-based materials in the field of biomedicine.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Yuanhui Xiang, Sijie Xian, Rachel C. Ollier, Sihan Yu, Bo Su, Irawan Pramudya, Matthew J. Webber
Summary: This study demonstrates the use of a new diboronate motif for preparing dynamic-covalent hydrogels with enhanced glucose binding and specificity, leading to improved glucose responsiveness and insulin release. Compared to traditional phenylboronic acid approaches, diboronate hydrogels show greater practicality.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Pharmacology & Pharmacy
Wipada Samprasit, Praneet Opanasopit, Benchawan Chamsai
Summary: Alpha-Mangostin-loaded mucoadhesive nanoparticles were prepared using pH-dependent composite mucoadhesive nanoparticles. Different components and processing methods were found to affect the properties of the particles. In vitro experiments and anti-tumor activity tests confirmed the potential of these nanoparticles for colon-targeted drug delivery.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2021)
Article
Materials Science, Biomaterials
Hannah A. Pearce, Yu Seon Kim, Emma Watson, Kiana Bahrami, Mollie M. Smoak, Emily Y. Jiang, Michael Elder, Tate Shannon, Antonios G. Mikos
Summary: The field of biomaterials has made significant advancements in the past decade, with a growing focus on using microparticles as a platform for tissue engineering and drug delivery. Thiolated GMPs have been identified as a versatile and biocompatible platform for controlling cell ratios, growth factors, and drug release, showing great promise for modular applications in tissue engineering and drug delivery.
REGENERATIVE BIOMATERIALS
(2021)
Article
Chemistry, Multidisciplinary
E. Toufik, H. Noukrati, C. Rey, O. Marsan, C. Charvillat, S. Cazalbou, H. Ben Youcef, A. Barroug, C. Combes
Summary: This study investigated the setting chemical reaction, physicochemical properties, and in vitro evolution of calcium carbonate composite cements containing chitosan for bone applications. The presence of chitosan affected the structure and properties of the composite cement, and the formulation including 3.5 wt% chitosan showed optimal properties. The composite cement has potential as an injectable and resorbable bone substitute material.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Farzad Seidi, Mohsen Khodadadi Yazdi, Maryam Jouyandeh, Midhun Dominic, Haleh Naeim, Mojtaba Nasiri Nezhad, Babak Bagheri, Sajjad Habibzadeh, Payam Zarrintaj, Mohammad Reza Saeb, Masoud Mozafari
Summary: Polysaccharides are abundant carbohydrate polymers, with chitosan being the most widely used; blending chitosan with other polymers can improve its properties and bioactivity. This review paper summarizes progress in chitosan blends with biodegradable polymers and polysaccharides for biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Materials Science, Ceramics
Ranran Zhang, Nan Xu, Xujie Liu, Hao Yan, Jing Ma, Qingling Feng, Zhijian Shen
ADVANCES IN APPLIED CERAMICS
(2019)
Article
Chemistry, Physical
Qianli Huang, Xujie Liu, Ranran Zhang, Xing Yang, Chuwen Lan, Qingling Feng, Yong Liu
APPLIED SURFACE SCIENCE
(2019)
Article
Biochemical Research Methods
Amita M. Vaidya, Zhanhu Sun, Nadia Ayat, Andrew Schilb, Xujie Liu, Hongfa Jiang, Da Sun, Josef Scheidt, Victoria Qian, Siyuan He, Hannah Gilmore, William P. Schiemann, Zheng-Rong Lu
BIOCONJUGATE CHEMISTRY
(2019)
Article
Chemistry, Physical
Xujie Liu, Yong Xie, Shengjun Shi, Qingling Feng, Akash Bachhuka, Xiaodong Guo, Zhending She, Rongwei Tan, Qiang Cai, Krasimir Vasilev
APPLIED SURFACE SCIENCE
(2019)
Article
Biotechnology & Applied Microbiology
Wei He, Yudong Zheng, Qingling Feng, Tarek A. Elkhooly, Xujie Liu, Xing Yang, Yansen Wang, Yajie Xie
Letter
Oncology
Xujie Liu, Amita M. Vaidya, Da Sun, Yan Zhang, Nadia Ayat, Andrew Schilb, Zheng-Rong Lu
CANCER COMMUNICATIONS
(2020)
Article
Nanoscience & Nanotechnology
Zhaozhen Wang, Xujie Liu, Vidmi Taolam Martin, Mohamed Abdullahi Abdi, Lijun Chen, Yong Gong, Yiran Yan, Liming Song, Zhongxun Liu, Xianliao Zhang, Yan Chen, Bo Yu
JOURNAL OF NANOMATERIALS
(2020)
Article
Biochemistry & Molecular Biology
Wangqing Bian, Zhenxing Pan, Yakun Wang, Wei Long, Zefeng Chen, Niping Chen, Yaoxun Zeng, Jiongpeng Yuan, Xujie Liu, Yu-Jing Lu, Yan He, Kun Zhang
Summary: The study demonstrated the significant effectiveness of thiazole orange-based Mito-BWQ in tumor treatment by generating high heat to kill cancer cells through exogenous laser irradiation.
BIOORGANIC CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Xujie Liu, Yakun Wang, Yan He, Xiaofeng Wang, Ranran Zhang, Akash Bachhuka, Rahul Madathiparambil Visalakshan, Qingling Feng, Krasimir Vasilev
Summary: The study reveals that surface chemistry and topography can synergistically influence the morphology, focal adhesion formation, and osteogenic/adipogenic differentiation of human mesenchymal stem cells. This suggests that different material properties can have a significant impact on cell response and highlights the importance of designing functional biomaterials.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Biomaterials
Zixu Wang, Han Wang, Junjie Xiong, Jiahao Li, Xiaomin Miao, Xingzi Lan, Xujie Liu, Wenlong Wang, Nian Cai, Yadong Tang
Summary: In this study, a micro/nano hierarchical scaffold for bone tissue engineering was fabricated by combining MEW and SE techniques. The addition of gelatin nanofibers improved the hydrophilicity and slightly enhanced the mechanical strength of the scaffolds. MEW/SE composite scaffolds showed higher cell adhesion efficiency, improved cell proliferation, and higher osteoinductive ability compared to PCL MEW scaffolds.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Public, Environmental & Occupational Health
Wenxia Wang, Tingting Chen, Zhen Li, Qiting Tan, Zhenbang Meng, Hailun Qiu, Xujie Liu, Junxia Zheng
Summary: Different types of face masks were evaluated based on multiple international standards, with folding masks showing the highest particulate filtration efficiency and cup masks having the highest respiratory resistance. Generally, masks are more likely to meet the criteria of the EN149-2001+A1:2009 standard in terms of PFE, while meeting the requirements of the GB2626-2019 and NIOSH 42 CFR Part84-2019 standards for respiratory resistance is easier.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Materials Science, Multidisciplinary
Xujie Liu, Jiongpeng Yuan, Jian Zhang, Rahul Madathiparambil Visalakshan, Wenxia Wang, Yongxiao Xiang, Yan He, Qingling Feng, Krasimir Vasilev
Summary: The plasma deposited polyoxazoline (PPOx) with surface nanotopography gradient showed suppressed adhesion of S. aureus and enhanced initial attachment and spreading of hMSCs, as well as promoted osteogenic differentiation of hMSCs. The RhoA/ROCK signaling pathway may be involved in the enhancement of osteoinductive capacity of PPOx surface by nanotopography.
Article
Engineering, Biomedical
Zefeng Chen, Yaoxun Zeng, Niping Chen, Mingxia Zhang, Yakun Wang, Zhenxing Pan, Jiongpeng Yuan, Zhaoyi Ye, Xiaojing Li, Wangqing Bian, Haihong Li, Kun Zhang, Yan He, Xujie Liu
Summary: This study proposes a novel approach for the transport of metal ions using polyethylene glycol. By a simple synthesis method, 31 different metal ion-based nanoparticles were successfully synthesized and demonstrated their potential for cancer theranostics.
ADVANCED HEALTHCARE MATERIALS
(2022)
Review
Nanoscience & Nanotechnology
Wangqing Bian, Yakun Wang, Zhenxing Pan, Niping Chen, Xiaojing Li, Wing-Leung Wong, Xujie Liu, Yan He, Kun Zhang, Yu-Jing Lu
Summary: Photothermal therapy (PTT) is a promising approach for cancer treatment, with the potential to reduce the adverse effects of traditional chemotherapy. Recent research highlights the application of functionalized nanomaterials in PTT and combined therapies, offering new insights for future disease treatment.
ACS APPLIED NANO MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.
