Review
Biochemistry & Molecular Biology
Mohammed A. S. Abourehab, Sheersha Pramanik, Mohamed A. Abdelgawad, Bassam M. Abualsoud, Ammar Kadi, Mohammad Javed Ansari, A. Deepak
Summary: Chitosan, a naturally abundant cationic polymer, offers attractive characteristics such as renewability, hydrophilicity, biodegradability, biocompatibility, and antimicrobial activity. It has a wide range of applications in drug delivery, protective coatings, food packaging, and wastewater treatment. The structure of chitosan allows for various reactions and electrochemical interactions, improving its physicochemical properties. This review article discusses the extensive research on chitosan-based composites for drug, gene, protein, and vaccine delivery applications, as well as its applications in tissue engineering and wound healing. The challenges and future perspectives for chitosan in biomedical applications are also addressed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Multidisciplinary
Hai-Qing Song, Yaqian Fan, Yang Hu, Gang Cheng, Fu-Jian Xu
Summary: This review summarizes the potential and advantages of polysaccharide-peptide conjugates in biomedical applications, as well as provides an overview of the design, conjugation chemistry, and applications. In addition, the challenges and demands of polysaccharide-peptide conjugates are also discussed for future prospects.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Physical
Lijuan Wang, Yushuang Shang, Jie Zhang, Jiang Yuan, Jian Shen
Summary: The development of keratin-based biomaterials provides a valuable approach for addressing environmental pollutants and transforming waste into wealth. The properties and biomedical applications of keratin biomaterials, such as drug delivery, wound healing, and tissue engineering, are extensively discussed in this review, offering valuable insights for further research and development.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Hossein Omidian, Sumana Dey Chowdhury, Niloofar Babanejad
Summary: Cryogels, versatile biomaterials composed of synthetic and natural materials, have wide applications in tissue engineering, drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties remains challenging, and researchers are exploring advanced manufacturing techniques and addressing long-term stability. Combination therapies and drug delivery systems using cryogels show promise, but in vivo evaluation and clinical trials are crucial for determining safety and efficacy. Overcoming practical challenges such as scalability, structural integrity, mass transfer constraints, biocompatibility, seamless integration, and cost-effectiveness is essential for the successful application of cryogels in biomedical fields.
Review
Biochemistry & Molecular Biology
Ayaz Mahmood, Dev Patel, Brandon Hickson, John DesRochers, Xiao Hu
Summary: Hydrogels from biopolymers have various characteristics and find wide applications in biomedicine, contributing to patient treatments and outcomes. Different types of biopolymer hydrogels can be synthesized for specific purposes, such as cell delivery and drug delivery, in the field of biomedicine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Applied
Yongtao Geng, Hang Xue, Zhenhe Zhang, Adriana C. Panayi, Samuel Knoedler, Wu Zhou, Bobin Mi, Guohui Liu
Summary: Chitosan and its derivatives have been widely used in the biomedical field due to their biodegradability, biocompatibility, antibacterial activity, and adhesive properties. However, the low solubility of chitosan at physiological pH limits its applications in systems requiring higher dissolving ability and suitable drug release rates. Carboxymethyl chitosan, as a water-soluble derivative, shows improved properties and is more suitable for wound healing, drug delivery, and tissue engineering applications. This review focuses on the bioactivities of carboxymethyl chitosan, including antibacterial, anticancer, antitumor, antioxidant, and antifungal effects, as well as its recent applications in wound healing, drug delivery, tissue engineering, bioimaging, and cosmetics.
CARBOHYDRATE POLYMERS
(2023)
Review
Polymer Science
Xiumei Li, Wanjia Xu, Yue Xin, Jiawei Yuan, Yuancheng Ji, Shengnan Chu, Junqiu Liu, Quan Luo
Summary: Polymer nanocomposites consist of polymer matrixes and nanoscaled fillers, providing enhanced characteristics for a wide range of biomedical applications. The introduction of supramolecular chemistry has led to the creation of intelligent biomedical materials with unique properties and tunable structures. Recent advances in biomedical applications like therapeutic delivery, bioimaging, and tissue engineering have leveraged the excellent properties of these materials.
Review
Chemistry, Physical
Showkeen Muzamil Bashir, Gulzar Ahmed Rather, Ana Patricio, Zulfiqar Haq, Amir Amin Sheikh, Mohd Zahoor ul Haq Shah, Hemant Singh, Azmat Alam Khan, Sofi Imtiyaz, Sheikh Bilal Ahmad, Showket Nabi, Rabia Rakhshan, Saqib Hassan, Pedro Fonte
Summary: Chitosan is a versatile natural polymer with biodegradable and biocompatible properties. It has been extensively explored in various biomedical applications, including wound treatment, nanocarriers, and tissue-engineering scaffolds. The antibacterial, antioxidant, and haemostatic properties of chitosan make it an excellent option for wound dressings, and its hydrophilic nature makes it an ideal starting material for biocompatible and biodegradable hydrogels.
Review
Chemistry, Applied
Masoud Hamidi, Oseweuba Valentine Okoro, Peiman Brouki Milan, Mohammad Reza Khalili, Hadi Samadian, Lei Nie, Amin Shavandi
Summary: Fungal exopolysaccharides have diverse potential applications in various industries. However, there are only a few commercialized products based on fungal EPSs in the biomedical field. This review critically discusses the potential biomedical applications of fungal EPSs in tissue engineering, drug and gene delivery.
CARBOHYDRATE POLYMERS
(2022)
Review
Multidisciplinary Sciences
Wenjun Feng, Zhengke Wang
Summary: Chitosan (CS) and graphene oxide (GO) nanocomposites have great potential in biomedical applications. Nanocomposites based on CS and GO, with the synergistic effect between them, can be used in various forms for drug delivery, wound healing, bone tissue engineering, and biosensors.
Review
Chemistry, Applied
Varun Pawariya, Soumik De, Joydeep Dutta
Summary: Chitosan, a natural polycationic polysaccharide, can be modified due to its reactive functional groups. This review discusses the synthesis of various chitosan-based Schiff bases (CSBs) by reacting chitosan's amino groups with different aldehydes/ketones. The unique characteristics of CSBs, such as biodegradability and metal-binding capability, make them useful in biomedical and industrial applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Pharmacology & Pharmacy
Yang Gao, Qingming Ma, Jie Cao, Yiwen Wang, Xin Yang, Qiulong Xu, Qing Liang, Yong Sun
Summary: The review highlights the recent progress in fabricating chitosan-based biomaterials using microfluidic technology, emphasizing the precise control over morphology and microstructures, as well as the potential applications of chitosan-based materials in the field of biomedicine.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Review
Engineering, Environmental
Akbar Mirzaei, Maryam Esmkhani, Mahsa Zallaghi, Zahra Nezafat, Shahrzad Javanshir
Summary: Carrageenan, a renewable polymer derived from red algae, has valuable properties such as water absorption, gel formation, and antibacterial effects. It shows great potential in biomedical and environmental applications.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Review
Biochemistry & Molecular Biology
Wei Xiang, Hui Cao, Hai Tao, Lin Jin, Yue Luo, Fenghua Tao, Ting Jiang
Summary: Spinal cord injury (SCI)-related disabilities are a serious problem that needs urgent treatment. Chitosan-based biomaterials have proven to be effective in promoting SCI repair by promoting neural cell growth, guiding nerve tissue regeneration, delivering nerve growth factors, and serving as a vector for gene therapy. This review aims to introduce recent advances in chitosan-based biomaterials for SCI treatment and highlight their prospects for further application.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Multidisciplinary
Xiang Lin, Jinglin Wang, Xiangyi Wu, Yuan Luo, Yongan Wang, Yuanjin Zhao
Summary: Marine organisms provide valuable resources for biomaterials, especially natural hydrogels, which have outstanding bioactivity and biocompatibility. These hydrogels can not only mimic tissue extracellular matrix but also be applied in biomedicine through various techniques. This review summarizes the classification and characteristics of marine-derived hydrogels, introduces their role in biomaterial development, and discusses the influence of hydrogel types on their functions in biomedical applications.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Morteza Motahari Rad, Nahid Bijeh, Seyyed Reza Attarzadeh Hosseini, Aliakbar Raouf Saeb
Summary: This study investigated the effects of different sequences of concurrent training on adults with type 2 diabetes mellitus. The results showed that regardless of the sequence, concurrent training increased irisin and FST concentrations while decreasing MSTN concentrations. Additionally, concurrent training improved body composition, strength, and peak oxygen uptake.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Review
Biotechnology & Applied Microbiology
Negin Jalilinejad, Mohammad Rabiee, Nafiseh Baheiraei, Ramin Ghahremanzadeh, Reza Salarian, Navid Rabiee, Omid Akhavan, Payam Zarrintaj, Aleksander Hejna, Mohammad Reza Saeb, Ali Zarrabi, Esmaeel Sharifi, Satar Yousefiasl, Ehsan Nazarzadeh Zare
Summary: Human cardiac tissue lacks proper self-regenerating capability, making tissue engineering critical for addressing the growing rate of deaths associated with cardiovascular disorders. Carbon-based nanomaterials, specifically their conductivity, have revolutionized tissue engineering by providing an appropriate microenvironment for cell protection against attacking mechanisms. The use of conductive biomaterials in cardiac tissue engineering, including graphene, graphene oxide, carbon nanotubes, and carbon nanofibers, has been studied extensively.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Correction
Chemistry, Multidisciplinary
Narendra Pal Singh Chauhan, Masoud Mozafari, Narendra Singh Chundawat, Kiran Meghwal, Rakshit Ameta, Suresh C. Ameta
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Mehdi Bazi Alahri, Alhawarin Jibril Ibrahim, Mahmood Barani, Hassan Arkaban, Seyedeh Malahat Shadman, Soodeh Salarpour, Payam Zarrintaj, Javad Jaberi, Abduladheem Turki Jalil
Summary: The blood-brain barrier restricts drug entry into the brain and poses a challenge in CNS disease treatment. Nanotechnology-based delivery systems with polymer coatings, such as HSA, PLGA, PLA, PACA, gelatin, and chitosan, have been developed to overcome this barrier and deliver drugs to the brain. The review article discusses the application of polymer-coated nanoparticles as novel drug carriers to the brain.
Editorial Material
Chemistry, Physical
Paulina Wisniewska, Aleksander Hejna, Mohammad Reza Saeb
Article
Materials Science, Multidisciplinary
Fouad Laoutid, Maryam Jouyandeh, Oltea Murariu, Henri Vahabi, Mohammad Reza Saeb, Loic Brison, Marius Murariu, Philippe Dubois
Summary: This study investigated the flame-retardant effect of transparent epoxy coating with aluminum hypophosphite nanoparticles on polylactic acid sheets. The addition of these nanoparticles into the epoxy resin accelerated the degradation of the coating, resulting in increased char residue. The presence of the nanoparticles reduced the peak heat release rate significantly, leading to the formation of a homogeneous char layer with a 15 wt.% nanoparticle content. However, further increase in content did not enhance the flame-retardant properties due to the formation of structural cracks in the coating.
Article
Materials Science, Multidisciplinary
Shukufe Amukarimi, Iman Mobasherpour, Sorosh Abdollahi, Peiman Brouki Milan, Masoud Mozafari
Summary: Thanks to prophylactic antibiotics, the risk of wound infection in orthopedic surgeries has significantly decreased. This study focuses on the effectiveness of a new biodegradable antibiotic-loaded coating on the surface of a magnesium implant. The results show that the coating is biocompatible, antibacterial, and has improved corrosion resistance, making it potentially suitable for bone regeneration applications.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Multidisciplinary Sciences
Mohamed S. Hasanin, Mona Nassar, Youssef R. Hassan, Lukasz Piszczyk, Mohammad Reza Saeb, Agata Kot-Wasik
Summary: Fluorescence is an efficient anti-counterfeiting technique, and zinc oxide quantum dots (ZnOQds) possess strong fluorescence under ultraviolet (UV) light, making them suitable for anti-counterfeiting printing. In this study, ZnOQds were prepared using a green method and characterized by various techniques. The resulting ZnOQds nanocrystals showed stability and resistance against organic dyes. Furthermore, hybrid sheets made with ZnOQds demonstrated greater mechanical stability, long-term stability, and antimicrobial activity.
Correction
Nanoscience & Nanotechnology
Navid Rabiee, Mojtaba Bagherzadeh, Amir Mohammad Ghadiri, Yousef Fatahi, Abdullah Aldhaher, Pooyan Makvandi, Rassoul Dinarvand, Maryam Jouyandeh, Mohammad Reza Saeb, Masoud Mozafari, Mohammadreza Shokouhimehr, Michael R. Hamblin, Rajender S. Varma
ACS APPLIED BIO MATERIALS
(2023)
Article
Engineering, Biomedical
Ali Sadeghi, Ehsan Afshari, Mohadeseh Hashemi, David Kaplan, Masoud Mozafari
Summary: Neural interfaces (NIs) are neuroengineering tools that enable a mutual communication pathway with the nervous system. Smart biomaterials (SBMs) such as stimuli-responsive and shape memory biomaterials emerged as novel materials with exceptional properties, enhancing the function of NIs and opening new possibilities in neuroscience studies and neuromodulation therapies.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Engineering, Biomedical
Mir Saman Safavi, Aydin Bordbar-Khiabani, Frank C. Walsh, Masoud Mozafari, Jafar Khalil-Allafi
Summary: NiTi metallic biomaterials have a wide range of clinical applications, and the use of NiTi smart biomaterials has gained attention for their unique features. Surface-modification techniques, including dry and wet coating techniques, have been employed to improve the biological properties of NiTi before clinical use. R&D activities have shown progress, but more work needs to be done before coated-NiTi can be used clinically.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Oncology
Ali Salehi, Parvaneh Naserzadeh, Parastoo Tarighi, Elham Afjeh-Dana, Masoud Akhshik, Amir Jafari, Pooyan Mackvandi, Behnaz Ashtari, Masoud Mozafari
Summary: Breast cancer is a prevalent cancer in women, and microfluidic devices show promise in advancing research in this field. This study used a dynamic cell culture condition in a microfluidic concentration gradient device to assess the anticancer activities of probiotic strains against breast cancer cells. The findings revealed that a specific concentration of probiotic supernatant induced more cell death signaling after 48 hours. Additionally, the evaluated optimum dose was lower than the conventional treatment dose. Flow cytometric assessment confirmed that cell death signaling was concentration and time dependent. This study demonstrates the potential benefits of microfluidic platforms in personalized medicine and cancer therapy.
TRANSLATIONAL ONCOLOGY
(2023)
Article
Oncology
Przemys law Gnatowski, Edyta Pilat, Justyna Kucinska-Lipka, Mohammad Reza Saeb, Michael R. Hamblin, Masoud Mozafari
Summary: Cancerous tumors are highly fatal, claiming almost 10 million lives in 2020 worldwide. Accurately modeling tumors is a challenging task due to their complex and dynamic nature. Hydrogel-based 3D bioprinting is emerging as a promising approach to overcome the limitations of current models and mimic cancer development and behavior.
TRANSLATIONAL ONCOLOGY
(2023)
Article
Engineering, Biomedical
Hanieh Shokrani, Amirhossein Shokrani, Farzad Seidi, Justyna Kucinska-Lipka, Balbina Makurat-Kasprolewicz, Mohammad Reza Saeb, Seeram Ramakrishna
Summary: The concept of 'making computers think like people' is supported by computer-aided concepts, cognitive algorithms, fuzzy sets, and fuzzy logic thoughts. This idea enables the development of biomaterials and biosystems with the aid of Artificial Intelligence (AI). In the field of PSA-based biomedical engineering, AI-based algorithms play an important role in improving performance and optimizing scenarios.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
