Engineering approaches for effective therapeutic applications based on extracellular vesicles
出版年份 2020 全文链接
标题
Engineering approaches for effective therapeutic applications based on extracellular vesicles
作者
关键词
Extracellular vesicles, Therapeutic applications, Preconditioning, Drug loading, Surface modification, Biogenesis inhibition
出版物
JOURNAL OF CONTROLLED RELEASE
Volume 330, Issue -, Pages 15-30
出版商
Elsevier BV
发表日期
2020-12-03
DOI
10.1016/j.jconrel.2020.11.062
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The biology, function, and biomedical applications of exosomes
- (2020) Raghu Kalluri et al. SCIENCE
- Preparation of Internalizing RGD-Modified Recombinant Methioninase Exosome Active Targeting Vector and Antitumor Effect Evaluation
- (2020) Lin Xin et al. DIGESTIVE DISEASES AND SCIENCES
- Three-dimensional culture of MSCs produces exosomes with improved yield and enhanced therapeutic efficacy for cisplatin-induced acute kidney injury
- (2020) Jingyuan Cao et al. Stem Cell Research & Therapy
- Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency
- (2019) Christina Schindler et al. PLoS One
- Exosome-based antisense locked nucleic acid delivery for inhibition of type II collagen degradation in chondrocyte
- (2019) Kyeongsoo Jeong et al. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders
- (2019) Milad Riazifar et al. ACS Nano
- TNF‐α‐induced exosomal miR‐146a mediates mesenchymal stem cell‐dependent suppression of urethral stricture
- (2019) Ying‐Chun Liang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance
- (2019) Selma Maacha et al. Molecular Cancer
- Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Stimulated by Deferoxamine Accelerate Cutaneous Wound Healing by Promoting Angiogenesis
- (2019) Jianing Ding et al. Biomed Research International
- Delivery of miR-675 by stem cell-derived exosomes encapsulated in silk fibroin hydrogel prevents aging-induced vascular dysfunction in mouse hindlimb
- (2019) Chaoshan Han et al. Materials Science & Engineering C-Materials for Biological Applications
- KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a
- (2019) Lin Song et al. Nature Communications
- Exosomes derived from pro‐inflammatory bone marrow‐derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage polarization
- (2019) Ruqin Xu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy
- (2019) Chunai Gong et al. JOURNAL OF NANOBIOTECHNOLOGY
- Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?
- (2019) Elaheh Mianehsaz et al. Stem Cell Research & Therapy
- Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro
- (2019) Ciarra Almeria et al. Frontiers in Bioengineering and Biotechnology
- The Regulatory Functionality of Exosomes Derived from hUMSCs in 3D Culture for Alzheimer's Disease Therapy
- (2019) Lingyan Yang et al. Small
- Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
- (2019) Xiaodong Xie et al. Nature Communications
- Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation
- (2019) Zhaogang Yang et al. Nature Biomedical Engineering
- Inhibiting extracellular vesicles formation and release: a review of EV inhibitors
- (2019) Mariadelva Catalano et al. Journal of Extracellular Vesicles
- Methotrexate-Loaded Extracellular Vesicles Functionalized with Therapeutic and Targeted Peptides for the Treatment of Glioblastoma Multiforme
- (2018) Zhilan Ye et al. ACS Applied Materials & Interfaces
- Strategic design of extracellular vesicle drug delivery systems
- (2018) James P.K. Armstrong et al. ADVANCED DRUG DELIVERY REVIEWS
- Facile metabolic glycan labeling strategy for exosome tracking
- (2018) Tae Sup Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
- (2018) Tian Tian et al. BIOMATERIALS
- Cancer-derived exosomes from HER2-positive cancer cells carry trastuzumab-emtansine into cancer cells leading to growth inhibition and caspase activation
- (2018) Mark Barok et al. BMC CANCER
- Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice
- (2018) Guo-Hong Cui et al. FASEB JOURNAL
- Comparison of exosomes and ferritin protein nanocages for the delivery of membrane protein therapeutics
- (2018) Eunji Cho et al. JOURNAL OF CONTROLLED RELEASE
- Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy
- (2018) Xianjun Gao et al. Science Translational Medicine
- Exosomes Derived from Hypoxia-Treated Human Adipose Mesenchymal Stem Cells Enhance Angiogenesis Through the PKA Signaling Pathway
- (2018) Chunling Xue et al. STEM CELLS AND DEVELOPMENT
- Efficient RNA drug delivery using red blood cell extracellular vesicles
- (2018) Waqas Muhammad Usman et al. Nature Communications
- Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine – a new paradigm for tissue repair
- (2018) I. M. Bjørge et al. Biomaterials Science
- Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression
- (2018) Eduard Willms et al. Frontiers in Immunology
- Antimicrobial effects of mesenchymal stem cells primed by modified LPS on bacterial clearance in sepsis
- (2018) Pardis Saeedi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Exosomes produced from three-dimensional cultures of mesenchymal stem cells by tangential flow filtration show higher yield and improved activity
- (2018) Reka Agnes Haraszti et al. MOLECULAR THERAPY
- Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
- (2018) Gang Chen et al. NATURE
- Circulating Extracellular Vesicles in Human Disease
- (2018) Ravi Shah et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes
- (2018) Rossana Domenis et al. Scientific Reports
- The Future of Bioorthogonal Chemistry
- (2018) Neal K. Devaraj ACS Central Science
- Efficient Delivery of Tyrosinase Related Protein‐2 (TRP2) Peptides to Lymph Nodes using Serum‐Derived Exosomes
- (2018) Ok Park et al. MACROMOLECULAR BIOSCIENCE
- Proteins Regulating Microvesicle Biogenesis and Multidrug Resistance in Cancer
- (2018) Jack Taylor et al. PROTEOMICS
- The emerging role of exosome and microvesicle- (EMV-) based cancer therapeutics and immunotherapy
- (2017) Colin Moore et al. INTERNATIONAL JOURNAL OF CANCER
- Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy
- (2017) Uchini Kosgodage et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pseudotyping exosomes for enhanced protein delivery in mammalian cells
- (2017) Conary Meyer et al. International Journal of Nanomedicine
- Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis
- (2017) Nao Nishida-Aoki et al. MOLECULAR THERAPY
- Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis
- (2017) Yuxian Song et al. STEM CELLS
- Inflammation-Stimulated Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Inflammation
- (2017) Matthew T. Harting et al. STEM CELLS
- Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth
- (2017) Daniele Bellavia et al. Theranostics
- Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia
- (2017) Jialei Yang et al. Molecular Therapy-Nucleic Acids
- Antimicrobial Activity of Mesenchymal Stem Cells: Current Status and New Perspectives of Antimicrobial Peptide-Based Therapies
- (2017) Francisca Alcayaga-Miranda et al. Frontiers in Immunology
- Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis
- (2017) Ma Yubo et al. PLoS One
- Cellular Engineering with Membrane Fusogenic Liposomes to Produce Functionalized Extracellular Vesicles
- (2016) Junsung Lee et al. ACS Applied Materials & Interfaces
- Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy
- (2016) Hongzhao Qi et al. ACS Nano
- Extracellular vesicles for drug delivery
- (2016) Pieter Vader et al. ADVANCED DRUG DELIVERY REVIEWS
- Efficient production and enhanced tumor delivery of engineered extracellular vesicles
- (2016) Dionysios C. Watson et al. BIOMATERIALS
- Exosomal formulation enhances therapeutic response of celastrol against lung cancer
- (2016) Farrukh Aqil et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Exosomes: Tunable Nano Vehicles for Macromolecular Delivery of Transferrin and Lactoferrin to Specific Intracellular Compartment
- (2016) Himanshu Malhotra et al. Journal of Biomedical Nanotechnology
- PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time
- (2016) S.A.A. Kooijmans et al. JOURNAL OF CONTROLLED RELEASE
- Electrical stimulation to optimize cardioprotective exosomes from cardiac stem cells
- (2016) C.R. Campbell et al. MEDICAL HYPOTHESES
- Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing
- (2016) Marie-Cécile Didiot et al. MOLECULAR THERAPY
- SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions
- (2016) F. Pucci et al. SCIENCE
- Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
- (2016) Nambin Yim et al. Nature Communications
- Mechanisms of mesenchymal stem/stromal cell function
- (2016) Jeffrey L. Spees et al. Stem Cell Research & Therapy
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
- (2016) Hongyun Zhao et al. eLife
- Stem Cell Therapies in Clinical Trials: Progress and Challenges
- (2015) Alan Trounson et al. Cell Stem Cell
- Increased anti-tumour activity by exosomes derived from doxorubicin-treated tumour cells via heat stress
- (2015) Yunshan Yang et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Stabilization of Exosome-targeting Peptides via Engineered Glycosylation
- (2015) Michelle E. Hung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins
- (2015) Gregor Fuhrmann et al. JOURNAL OF CONTROLLED RELEASE
- Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells
- (2015) Heikki Saari et al. JOURNAL OF CONTROLLED RELEASE
- Melatonin facilitates adipose-derived mesenchymal stem cells to repair the murine infarcted heartviathe SIRT1 signaling pathway
- (2015) Dong Han et al. JOURNAL OF PINEAL RESEARCH
- LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b
- (2015) Dongdong Ti et al. Journal of Translational Medicine
- Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis
- (2015) Fatemeh Momen-Heravi et al. Journal of Translational Medicine
- Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery
- (2015) Tek N. Lamichhane et al. MOLECULAR PHARMACEUTICS
- Tumour exosome integrins determine organotropic metastasis
- (2015) Ayuko Hoshino et al. NATURE
- Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio
- (2015) Tianzhi Yang et al. PHARMACEUTICAL RESEARCH
- Differential fates of biomolecules delivered to target cells via extracellular vesicles
- (2015) Masamitsu Kanada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse
- (2015) Yuchen Liu et al. Scientific Reports
- Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake
- (2015) Michael P. Plebanek et al. Scientific Reports
- Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo
- (2015) Samireh Jorfi et al. Scientific Reports
- Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter
- (2014) Charles P. Lai et al. ACS Nano
- Surface Functionalization of Exosomes Using Click Chemistry
- (2014) Tyson Smyth et al. BIOCONJUGATE CHEMISTRY
- Static magnetic field enhances synthesis and secretion of membrane-derived microvesicles (MVs) rich in VEGF and BMP-2 in equine adipose-derived stromal cells (EqASCs)—a new approach in veterinary regenerative medicine
- (2014) Monika Marędziak et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Extracellular vesicles as drug delivery systems: Lessons from the liposome field
- (2014) Roy van der Meel et al. JOURNAL OF CONTROLLED RELEASE
- Melatonin regulates mesenchymal stem cell differentiation: a review
- (2014) Francesca Luchetti et al. JOURNAL OF PINEAL RESEARCH
- Exosomes secreted by human cells transport largely mRNA fragments that are enriched in the 3′-untranslated regions
- (2013) Arsen O Batagov et al. Biology Direct
- A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
- (2013) Yanhua Tian et al. BIOMATERIALS
- Mesenchymal stromal cells from patients with myelodyplastic syndrome display distinct functional alterations that are modulated by lenalidomide
- (2013) R. A. Ferrer et al. HAEMATOLOGICA
- Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1
- (2013) Katrin J. Svensson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis
- (2013) Nobuyoshi Kosaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection
- (2013) Yuki Takahashi et al. JOURNAL OF BIOTECHNOLOGY
- A Microscopic View of Phospholipid Insertion into Biological Membranes
- (2013) Josh V. Vermaas et al. JOURNAL OF PHYSICAL CHEMISTRY B
- ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion
- (2013) Sabrina Schlienger et al. MOLECULAR BIOLOGY OF THE CELL
- Extracellular vesicles: biology and emerging therapeutic opportunities
- (2013) Samir EL Andaloussi et al. NATURE REVIEWS DRUG DISCOVERY
- Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression
- (2012) A. Bobrie et al. CANCER RESEARCH
- LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gi-alpha dependent PI-3kinase signalling
- (2012) Anta Ngkelo et al. Journal of Inflammation-London
- Exosome removal as a therapeutic adjuvant in cancer
- (2012) Annette M Marleau et al. Journal of Translational Medicine
- Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
- (2012) Shin-ichiro Ohno et al. MOLECULAR THERAPY
- Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
- (2012) Maria Francesca Baietti et al. NATURE CELL BIOLOGY
- RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells
- (2012) B Li et al. ONCOGENE
- Tumor-Derived Microvesicles Induce Proangiogenic Phenotype in Endothelial Cells via Endocytosis
- (2012) Taisuke Kawamoto et al. PLoS One
- Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth
- (2012) Hongqi Xin et al. STEM CELLS
- Interaction and uptake of exosomes by ovarian cancer cells
- (2011) Cristina Escrevente et al. BMC CANCER
- Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
- (2011) Bence György et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy
- (2011) Valentina Ciravolo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Formulation and Evaluation of Celastrol-Loaded Liposomes
- (2011) Jie Song et al. MOLECULES
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3
- (2011) T. Aung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mammalian cell transfection: the present and the future
- (2010) Tae Kyung Kim et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Site-Specific Incorporation ofp-Propargyloxyphenylalanine in a Cell-Free Environment for Direct Protein−Protein Click Conjugation
- (2010) Bradley C. Bundy et al. BIOCONJUGATE CHEMISTRY
- Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells
- (2010) Antonina Lavrentieva et al. Cell Communication and Signaling
- Small Molecule Inhibitors of Acid Sphingomyelinase
- (2010) Christoph Arenz CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
- (2010) Nobuyoshi Kosaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C
- (2010) Chieh Hsu et al. JOURNAL OF CELL BIOLOGY
- Cellular Internalization of Exosomes Occurs Through Phagocytosis
- (2010) Du Feng et al. TRAFFIC
- Circulating tumour-derived microvesicles in plasma of gastric cancer patients
- (2009) Jaroslaw Baran et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner
- (2009) Luize G. Lima et al. CANCER LETTERS
- ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles
- (2009) Vandhana Muralidharan-Chari et al. CURRENT BIOLOGY
- Is the intravascular administration of mesenchymal stem cells safe?
- (2009) Dario Furlani et al. MICROVASCULAR RESEARCH
- Rab27a and Rab27b control different steps of the exosome secretion pathway
- (2009) Matias Ostrowski et al. NATURE CELL BIOLOGY
- Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
- (2009) K. Al-Nedawi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Click Chemistry, A Powerful Tool for Pharmaceutical Sciences
- (2008) Christopher D. Hein et al. PHARMACEUTICAL RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started