Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?
出版年份 2019 全文链接
标题
Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?
作者
关键词
-
出版物
Stem Cell Research & Therapy
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-21
DOI
10.1186/s13287-019-1445-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stem Cell-Derived Extracellular Vesicles for Treating Joint Injury and Osteoarthritis
- (2019) Jiao Li et al. Nanomaterials
- Exosomes derived from mesenchymal stem cells inhibit mitochondrial dysfunction-induced apoptosis of chondrocytes via p38, ERK, and Akt pathways
- (2019) Hui Qi et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Bioactive factors for cartilage repair and regeneration: Improving delivery, retention, and activity
- (2019) Jay M. Patel et al. Acta Biomaterialia
- MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis
- (2019) Shipin Zhang et al. BIOMATERIALS
- MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity
- (2018) Shipin Zhang et al. BIOMATERIALS
- Exosomes and Stem Cells in Degenerative Disease Diagnosis and Therapy
- (2018) Yu-Hsun Chang et al. CELL TRANSPLANTATION
- Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes
- (2018) Miguel Tofiño-Vian et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Emerging Role of Exosomes in the Joint Diseases
- (2018) Zeng Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- MiR-548a-3p regulates inflammatory response via TLR4/NF-κB signaling pathway in rheumatoid arthritis
- (2018) Yingliang Wang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Intra-articular injections of expanded mesenchymal stem cells with and without addition of platelet-rich plasma are safe and effective for knee osteoarthritis
- (2018) Ricardo Bastos et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- Extracellular vesicles and microvascular pathology: decoding the active dialogue
- (2018) Elham Hosseini Beheshti et al. MICROCIRCULATION
- Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
- (2018) Haiying Zhang et al. NATURE CELL BIOLOGY
- Exosomes and regenerative medicine: state of the art and perspectives
- (2018) Hui Jing et al. Translational Research
- Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro
- (2018) Lucienne A. Vonk et al. Theranostics
- Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis
- (2018) Stella Cosenza et al. Theranostics
- Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis
- (2018) Ye Zhao et al. INTERNATIONAL ORTHOPAEDICS
- Expression of exosomal microRNAs during chondrogenic differentiation of human bone mesenchymal stem cells
- (2018) Hao Sun et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Exosome-encapsulated miR-6089 regulates inflammatory response via targeting TLR4
- (2018) Donghua Xu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Therapeutic Potential of Mesenchymal Cell–Derived miRNA-150-5p–Expressing Exosomes in Rheumatoid Arthritis Mediated by the Modulation of MMP14 and VEGF
- (2018) Zhe Chen et al. JOURNAL OF IMMUNOLOGY
- Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II)
- (2018) José María Lamo-Espinosa et al. Journal of Translational Medicine
- Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting WNT5A
- (2018) Guping Mao et al. Stem Cell Research & Therapy
- Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
- (2018) Jose Matas et al. Stem Cells Translational Medicine
- Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents
- (2017) Verena Börger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Characterization of the Proinflammatory Profile of Synovial Fluid-Derived Exosomes of Patients with Osteoarthritis
- (2017) Rossana Domenis et al. MEDIATORS OF INFLAMMATION
- Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts
- (2017) Miguel Tofiño-Vian et al. Oxidative Medicine and Cellular Longevity
- Lipids in exosomes: Current knowledge and the way forward
- (2017) Tore Skotland et al. PROGRESS IN LIPID RESEARCH
- MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment
- (2017) Wei Seong Toh et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration
- (2017) Yao Fu et al. TISSUE ENGINEERING PART B-REVIEWS
- Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
- (2017) Liliane Christ et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis
- (2017) Stella Cosenza et al. Scientific Reports
- Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis
- (2017) Yu Zhu et al. Stem Cell Research & Therapy
- Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix
- (2017) Yafei Wang et al. Stem Cell Research & Therapy
- Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model
- (2017) Shi-Cong Tao et al. Theranostics
- Intra-articular injection of expanded autologous bone marrow mesenchymal cells in moderate and severe knee osteoarthritis is safe: a phase I/II study
- (2017) Mahasen Al-Najar et al. Journal of Orthopaedic Surgery and Research
- Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
- (2017) Agnes T. Reiner et al. Stem Cells Translational Medicine
- Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis
- (2017) Ma Yubo et al. PLoS One
- Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis
- (2017) Ravindra Kolhe et al. Scientific Reports
- Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
- (2016) Annette Becker et al. CANCER CELL
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
- (2016) Mercedes Tkach et al. CELL
- Intra-Articular Cellular Therapy for Osteoarthritis and Focal Cartilage Defects of the Knee
- (2016) Jorge Chahla et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Synovium-Derived MicroRNAs Regulate Bone Pathways in Rheumatoid Arthritis
- (2016) Yukiko Maeda et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
- (2016) José M. Lamo-Espinosa et al. Journal of Translational Medicine
- Final results of a phase I–II trial using ex vivo expanded autologous Mesenchymal Stromal Cells for the treatment of osteoarthritis of the knee confirming safety and suggesting cartilage regeneration
- (2016) Robert Soler et al. KNEE
- Synovial mesenchymal stem cells from osteo- or rheumatoid arthritis joints exhibit good potential for cartilage repair using a scaffold-free tissue engineering approach
- (2016) K. Koizumi et al. OSTEOARTHRITIS AND CARTILAGE
- Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration
- (2016) S. Zhang et al. OSTEOARTHRITIS AND CARTILAGE
- Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys
- (2016) François Rannou et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- Intra-articular treatment of knee osteoarthritis: from anti-inflammatories to products of regenerative medicine
- (2016) Masters M. Richards et al. PHYSICIAN AND SPORTSMEDICINE
- Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21
- (2016) Kan Wang et al. Stem Cells Translational Medicine
- Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial
- (2016) Yves-Marie Pers et al. Stem Cells Translational Medicine
- Cells release subpopulations of exosomes with distinct molecular and biological properties
- (2016) Eduard Willms et al. Scientific Reports
- ALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signaling
- (2016) Vincent Mercier et al. Scientific Reports
- Human Endothelial Colony-Forming Cells Protect against Acute Kidney Injury
- (2015) Dylan Burger et al. AMERICAN JOURNAL OF PATHOLOGY
- RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity
- (2015) Evangelos Pefanis et al. CELL
- Therapeutic application of mesenchymal stem cells in osteoarthritis
- (2015) Maxime Ruiz et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
- (2015) Nina Heldring et al. HUMAN GENE THERAPY
- Therapeutic Potential of Differentiated Mesenchymal Stem Cells for Treatment of Osteoarthritis
- (2015) Onju Ham et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesenchymal stem cell therapy for knee osteoarthritis: 5 years follow-up of three patients
- (2015) Fereydoun Davatchi et al. International Journal of Rheumatic Diseases
- Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
- (2015) V.B. Kraus et al. OSTEOARTHRITIS AND CARTILAGE
- Survival and Biodistribution of Xenogenic Adipose Mesenchymal Stem Cells Is Not Affected by the Degree of Inflammation in Arthritis
- (2015) Karine Toupet et al. PLoS One
- Socio-economic costs of osteoarthritis: A systematic review of cost-of-illness studies
- (2015) Jaume Puig-Junoy et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells
- (2015) Aurelio Vega et al. TRANSPLANTATION
- Mesenchymal Stem Cells Suppress Fibroblast Proliferation and Reduce Skin Fibrosis Through a TGF-β3-Dependent Activation
- (2015) Yan Wu et al. International Journal of Lower Extremity Wounds
- Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species
- (2015) Serena Rubina Baglio et al. Stem Cell Research & Therapy
- Double-stranded DNA in exosomes: a novel biomarker in cancer detection
- (2014) Basant Kumar Thakur et al. CELL RESEARCH
- MSC-Based Product Characterization for Clinical Trials: An FDA Perspective
- (2014) Michael Mendicino et al. Cell Stem Cell
- Biogenesis and secretion of exosomes
- (2014) Joanna Kowal et al. CURRENT OPINION IN CELL BIOLOGY
- Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer
- (2014) Christoph Kahlert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging regulators of the inflammatory process in osteoarthritis
- (2014) Ru Liu-Bryan et al. Nature Reviews Rheumatology
- The Burden of Musculoskeletal Conditions
- (2014) Clémence Palazzo et al. PLoS One
- Advances in Mesenchymal Stem Cell-based Strategies for Cartilage Repair and Regeneration
- (2014) Wei Seong Toh et al. Stem Cell Reviews and Reports
- Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes
- (2014) Tomohiro Kato et al. ARTHRITIS RESEARCH & THERAPY
- Exosomes/miRNAs as mediating cell-based therapy of stroke
- (2014) Hongqi Xin et al. Frontiers in Cellular Neuroscience
- Adipose-Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2
- (2013) Cristina Manferdini et al. ARTHRITIS AND RHEUMATISM
- Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes
- (2013) Marie Maumus et al. BIOCHIMIE
- Extracellular vesicles: Exosomes, microvesicles, and friends
- (2013) Graça Raposo et al. JOURNAL OF CELL BIOLOGY
- Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
- (2013) Johnny C. Akers et al. JOURNAL OF NEURO-ONCOLOGY
- Extracellular vesicles: biology and emerging therapeutic opportunities
- (2013) Samir EL Andaloussi et al. NATURE REVIEWS DRUG DISCOVERY
- Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis
- (2013) Marie Maumus et al. Stem Cell Research
- Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model
- (2013) Giovanna Desando et al. ARTHRITIS RESEARCH & THERAPY
- Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
- (2013) Taketoshi Kajimoto et al. Nature Communications
- Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis
- (2012) Menno ter Huurne et al. ARTHRITIS AND RHEUMATISM
- The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes
- (2012) Nathalie Cloutier et al. EMBO Molecular Medicine
- Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture
- (2012) G.M. van Buul et al. OSTEOARTHRITIS AND CARTILAGE
- Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis
- (2011) Yiying Qi et al. MOLECULAR BIOLOGY REPORTS
- Proteomic Analysis of Tumor Necrosis Factor-α-Induced Secretome of Human Adipose Tissue-Derived Mesenchymal Stem Cells
- (2010) Mi Jeong Lee et al. JOURNAL OF PROTEOME RESEARCH
- Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis and arthritis
- (2010) H Clarke Anderson et al. LABORATORY INVESTIGATION
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models
- (2009) Nicole R. Bianco et al. ARTHRITIS AND RHEUMATISM
- Mechanisms involved in the therapeutic properties of mesenchymal stem cells
- (2009) Lindolfo da Silva Meirelles et al. CYTOKINE & GROWTH FACTOR REVIEWS
- KEGG for representation and analysis of molecular networks involving diseases and drugs
- (2009) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
- (2009) Tian Sheng Chen et al. NUCLEIC ACIDS RESEARCH
- Calcification or dedifferentiation: Requirement to lock mesenchymal stem cells in a desired differentiation stage
- (2008) Andrea Dickhut et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
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