Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models

Propranolol for familial cerebral cavernous malformation (Treat_CCM): study protocol for a randomized controlled pilot trial

(2020) Silvia Lanfranconi et al.   Trials

Novel Murine Models of Cerebral Cavernous Malformations

(2020) Matthew R. Detter et al.   ANGIOGENESIS

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease

(2019) Robert Shenkar et al.   STROKE

Endothelial cell clonal expansion in the development of cerebral cavernous malformations

(2019) Matteo Malinverno et al.   Nature Communications

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

(2019) Jeroen Overman et al.   eLife

A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease

(2019) Lisa McKerracher et al.   Translational Stroke Research

Bleeding risk of cerebral cavernous malformations in patients on β-blocker medication: a cohort study

(2018) Johannes Goldberg et al.   JOURNAL OF NEUROSURGERY

Cerebral Cavernous Malformations Develop Through Clonal Expansion of Mutant Endothelial Cells

(2018) Matthew R. Detter et al.   CIRCULATION RESEARCH

B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models

(2016) Changbin Shi et al.   Journal of Neuroimmune Pharmacology

Propranolol stops progressive multiple cerebral cavernoma in an adult patient

(2016) Matthias Reinhard et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Medical management of vascular anomalies

(2016) Cameron C Trenor   SEMINARS IN CUTANEOUS MEDICINE AND SURGERY

A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma

(2015) Christine Léauté-Labrèze et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations

(2014) Robert Shenkar et al.   GENETICS IN MEDICINE

Successful treatment of multifocal intracerebral and spinal hemangiomas with propranolol

(2014) Juliette Miquel et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Effects of propranolol on heart rate and development in Japanese medaka (Oryzias latipes) and zebrafish (Danio rerio)

(2012) Juliane Finn et al.   AQUATIC TOXICOLOGY

Infantile intraspinal and extensive cutaneous hemangiomas: Excellent response to propranolol

(2011) P. S. Ghosh et al.   NEUROLOGY

Fasudil Decreases Lesion Burden in a Murine Model of Cerebral Cavernous Malformation Disease

(2011) David A. McDonald et al.   STROKE

Propranolol Treatment for a Giant Infantile Brain Cavernoma

(2010) Maria Moschovi et al.   JOURNAL OF CHILD NEUROLOGY

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

(2010) Rebecca A. Stockton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Zebrafish β-adrenergic receptor mRNA expression and control of pigmentation

(2009) Zhipeng Wang et al.   GENE

Biology of Vascular Malformations of the Brain

(2009) Gabrielle G. Leblanc et al.   STROKE