标题
Astrocytes in heavy metal neurotoxicity and neurodegeneration
作者
关键词
Heavy metals, Astrocytes, Neurotoxicity, Neurodegeneration, Glutamate
出版物
BRAIN RESEARCH
Volume 1752, Issue -, Pages 147234
出版商
Elsevier BV
发表日期
2021-01-06
DOI
10.1016/j.brainres.2020.147234
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Brain iron deposition is linked with cognitive severity in Parkinson’s disease
- (2020) George Edward Calver Thomas et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity
- (2020) Omamuyovwi M. Ijomone et al. NEUROTOXICITY RESEARCH
- Regulation of Iron Homeostasis and Related Diseases
- (2020) Yikun Li et al. MEDIATORS OF INFLAMMATION
- Toxic Metal Implications on Agricultural Soils, Plants, Animals, Aquatic life and Human Health
- (2020) Uchenna Okereafor et al. International Journal of Environmental Research and Public Health
- Cross-sectional and Longitudinal Assessment of Brain Iron Level in Alzheimer Disease Using 3-T MRI
- (2020) Anna Damulina et al. RADIOLOGY
- NF-κB signaling in astrocytes modulates brain inflammation and neuronal injury following sequential exposure to manganese and MPTP during development and aging
- (2020) Sean L Hammond et al. TOXICOLOGICAL SCIENCES
- Iron Aggravates the Depressive Phenotype of Stressed Mice by Compromising the Glymphatic System
- (2020) Shanshan Liang et al. Neuroscience Bulletin
- Serial assessment of iron in the motor cortex in limb-onset amyotrophic lateral sclerosis using quantitative susceptibility mapping
- (2020) Anjan Bhattarai et al. Quantitative Imaging in Medicine and Surgery
- Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment
- (2020) Paula Moyano et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Nitric Oxide, Iron and Neurodegeneration
- (2019) Chao Liu et al. Frontiers in Neuroscience
- Bioaccumulation of heavy metals in Channa punctatus (Bloch) in river Ramganga (U.P.), India
- (2019) Robeena Sarah et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine
- (2019) Aseel Eid et al. PHARMACOLOGY & THERAPEUTICS
- Treatments for iron deficiency (ID): Prospective organic iron fortification
- (2019) Dan Wan et al. CURRENT PHARMACEUTICAL DESIGN
- Iron concentrations in neurons and glial cells with estimates on ferritin concentrations
- (2019) Anja Reinert et al. BMC NEUROSCIENCE
- Memantine Is Protective against Cytotoxicity Caused by Lead and Quinolinic Acid in Cultured Rat Embryonic Hippocampal Cells
- (2019) Abdur Rahman et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Iron and other metals in the pathogenesis of Parkinson's disease: Toxic effects and possible detoxification
- (2019) Geir Bjørklund et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Brain iron transport
- (2019) Zhong‐Ming Qian et al. BIOLOGICAL REVIEWS
- Zinc oxide nanoparticle induced neurotoxic potential upon interaction with primary astrocytes
- (2019) S. Sudhakaran et al. NEUROTOXICOLOGY
- Associations of Iron Intake, Serum Iron and Serum Ferritin with Bone Mineral Density in Women: The National Health and Nutrition Examination Survey, 2005–2010
- (2019) Meihan Lu et al. CALCIFIED TISSUE INTERNATIONAL
- Risk assessment of soil heavy metals associated with land use variations in the riparian zones of a typical urban river gradient
- (2019) Shiliang Liu et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Effect of both selenium and biosynthesized nanoselenium particles on cadmium-induced neurotoxicity in albino rats
- (2019) MA Al Kahtani HUMAN & EXPERIMENTAL TOXICOLOGY
- Na+-dependent transporters: The backbone of astroglial homeostatic function
- (2019) Alexei Verkhratsky et al. CELL CALCIUM
- Examining the link between dose-dependent dietary iron intake and Alzheimer’s disease through oxidative stress in the rat cortex
- (2019) Hamid Ceylan et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration
- (2018) Matthew Neal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inorganic mercury in human astrocytes, oligodendrocytes, corticomotoneurons and the locus ceruleus: implications for multiple sclerosis, neurodegenerative disorders and gliomas
- (2018) Roger Pamphlett et al. BIOMETALS
- Involvement of gap junctions in astrocyte impairment induced by manganese exposure
- (2018) Cailing Lu et al. BRAIN RESEARCH BULLETIN
- Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats
- (2018) Hend M. Hussien et al. FOOD AND CHEMICAL TOXICOLOGY
- Metal Ion Effects on Aβ and Tau Aggregation
- (2018) Anne Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications
- (2018) Jordi Olloquequi et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice
- (2018) James Johnson et al. NEUROTOXICOLOGY
- Physiology of Astroglia
- (2018) Alexei Verkhratsky et al. PHYSIOLOGICAL REVIEWS
- The Aging of Iron Man
- (2018) Azhaar Ashraf et al. Frontiers in Aging Neuroscience
- Arsenic and heavy metals pollution along a salinity gradient in drained coastal wetland soils: Depth distributions, sources and toxic risks
- (2018) Junhong Bai et al. ECOLOGICAL INDICATORS
- Non-transferrin-bound iron transporters
- (2018) Mitchell D. Knutson FREE RADICAL BIOLOGY AND MEDICINE
- Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms
- (2018) Gunnar F. Kwakye et al. NEUROTOXICOLOGY
- Accumulation of heavy metals in soil-crop systems: a review for wheat and corn
- (2017) Shiyu Wang et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Overview of iron metabolism in health and disease
- (2017) Som Dev et al. Hemodialysis International
- Impact of iatrogenic iron overload on the course of hepatitis C in the dialysis population: A plea for caution
- (2017) Guy Rostoker et al. Hemodialysis International
- Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity
- (2017) Kelly S. Kirkley et al. Journal of Neuroinflammation
- Current view and perspectives in amyotrophic lateral sclerosis
- (2017) Stéphane Mathis et al. Neural Regeneration Research
- Iatrogenic iron overload and its potential consequences in patients on hemodialysis
- (2017) Guy Rostoker et al. PRESSE MEDICALE
- Antagonistic effects of lycopene on cadmium-induced hippocampal dysfunctions in autophagy, calcium homeostatis and redox
- (2017) Fenghua Zhang et al. Oncotarget
- Physicochemical properties of iron oxide nanoparticles that contribute to cellular ROS-dependent signaling and acellular production of hydroxyl radical
- (2016) Christoph F. A. Vogel et al. FREE RADICAL RESEARCH
- Principles of sodium homeostasis and sodium signalling in astroglia
- (2016) Christine R. Rose et al. GLIA
- Cytotoxicity and proliferative capacity impairment induced on human brain cell cultures after short- and long-term exposure to magnetite nanoparticles
- (2016) Teresa Coccini et al. JOURNAL OF APPLIED TOXICOLOGY
- Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics
- (2016) Abdel A. Belaidi et al. JOURNAL OF NEUROCHEMISTRY
- Are iron oxide nanoparticles safe? Current knowledge and future perspectives
- (2016) Vanessa Valdiglesias et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Mechanism of depression as a risk factor in the development of Alzheimer’s disease: the function of AQP4 and the glymphatic system
- (2016) Maosheng Xia et al. PSYCHOPHARMACOLOGY
- Decreased Plasma Iron in Alzheimer’s Disease Is Due to Transferrin Desaturation
- (2015) Dominic J. Hare et al. ACS Chemical Neuroscience
- The significance of caudate volume for age-related associative memory decline
- (2015) E. Bauer et al. BRAIN RESEARCH
- Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants
- (2015) Arif Jan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB and Yin Yang 1 (YY1)
- (2015) Pratap Karki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular mechanisms of non-transferrin-bound and transferring-bound iron uptake in primary hippocampal neurons
- (2015) Changyi Ji et al. JOURNAL OF NEUROCHEMISTRY
- Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation
- (2015) Juan G. Zarruk et al. NEUROBIOLOGY OF DISEASE
- Iron accumulation promotes TACE-mediated TNF-α secretion and neurodegeneration in a mouse model of ALS
- (2015) Jae Keun Lee et al. NEUROBIOLOGY OF DISEASE
- Developmental exposure to manganese induces lasting motor and cognitive impairment in rats
- (2015) Tanara V. Peres et al. NEUROTOXICOLOGY
- Longitudinal midbrain changes in early Parkinson's disease: Iron content estimated from R2*/MRI
- (2015) Marguerite Wieler et al. PARKINSONISM & RELATED DISORDERS
- Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases
- (2015) Miguel Chin-Chan et al. Frontiers in Cellular Neuroscience
- Iron entry in neurons and astrocytes: a link with synaptic activity
- (2015) Franca Codazzi et al. Frontiers in Molecular Neuroscience
- Editorial: Neuroinflammation and behavior
- (2015) Luba Sominsky et al. Frontiers in Neuroscience
- Uptake and metabolism of iron and iron oxide nanoparticles in brain astrocytes: Figure 1
- (2015) Michaela C. Hohnholt et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Astrocyte glutamine synthetase: pivotal in health and disease
- (2015) Christopher F. Rose et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis
- (2014) Wint Nandar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A Novel Model for Brain Iron Uptake: Introducing the Concept of Regulation
- (2014) Ian A Simpson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mercury-induced amyloid-beta (Aβ) accumulation in the brain is mediated by disruption of Aβ transport
- (2014) Dong-Kyeong Kim et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- The role of iron in brain ageing and neurodegenerative disorders
- (2014) Roberta J Ward et al. LANCET NEUROLOGY
- Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes
- (2014) P. Karki et al. MOLECULAR AND CELLULAR BIOLOGY
- An anemia of Alzheimer's disease
- (2014) N G Faux et al. MOLECULAR PSYCHIATRY
- Iron in multiple sclerosis: roles in neurodegeneration and repair
- (2014) Erin Stephenson et al. Nature Reviews Neurology
- Astroglial cradle in the life of the synapse
- (2014) A. Verkhratsky et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?
- (2014) Sara M. Hancock et al. Frontiers in Aging Neuroscience
- Pb Neurotoxicity: Neuropsychological Effects of Lead Toxicity
- (2014) Lisa H. Mason et al. Biomed Research International
- Iron Metabolism Disturbance in a French Cohort of ALS Patients
- (2014) Charlotte Veyrat-Durebex et al. Biomed Research International
- Microglial pathology
- (2014) Wolfgang J Streit et al. Acta Neuropathologica Communications
- A novel approach to rapidly prevent age-related cognitive decline
- (2013) Paul A. Adlard et al. AGING CELL
- Lead, Mercury, and Arsenic Poisoning Due to Topical Use of Traditional Chinese Medicines
- (2013) Ming-Ling Wu et al. AMERICAN JOURNAL OF MEDICINE
- A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice
- (2013) Wint Nandar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pro-inflammatory cytokines modulate iron regulatory protein 1 expression and iron transportation through reactive oxygen/nitrogen species production in ventral mesencephalic neurons
- (2013) Jia Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Iron uptake in quiescent and inflammation-activated astrocytes: A potentially neuroprotective control of iron burden
- (2013) Ilaria Pelizzoni et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Protective effects of lycopene against methylmercury-induced neurotoxicity in cultured rat cerebellar granule neurons
- (2013) Mingyue Qu et al. BRAIN RESEARCH
- Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration
- (2013) Hjalte Holm Andersen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Consequences of Iron Accumulation in Microglia and its Implications in Neuropathological Conditions
- (2013) Gurugirijha Rathnasamy et al. CNS & Neurological Disorders-Drug Targets
- Heavy metals in Australian grown and imported rice and vegetables on sale in Australia: Health hazard
- (2013) M. Azizur Rahman et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters
- (2013) Monika Mishra et al. EPILEPSY RESEARCH
- Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle
- (2013) M. Sidoryk-Wegrzynowicz et al. JOURNAL OF INTERNAL MEDICINE
- Brain iron MRI: A biomarker for amyotrophic lateral sclerosis
- (2013) Aleksandar Ignjatović et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
- (2013) Pamela Urrutia et al. JOURNAL OF NEUROCHEMISTRY
- The effects of early life Pb exposure on the expression of IL1-β, TNF-α and Aβ in cerebral cortex of mouse pups
- (2013) Ning Li et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes
- (2013) Patrícia Ramos et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Iron metabolism in the CNS: implications for neurodegenerative diseases
- (2013) Tracey A. Rouault NATURE REVIEWS NEUROSCIENCE
- Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation
- (2013) Ângela C. Crespo et al. NEUROBIOLOGY OF AGING
- Is R2* a New MRI Biomarker for the Progression of Parkinson’s Disease? A Longitudinal Follow-Up
- (2013) Miguel Ulla et al. PLoS One
- Is There a Cerebral Lymphatic System?
- (2013) J. J. Iliff et al. STROKE
- Iron and hepcidin: a story of recycling and balance
- (2013) C. Camaschella Hematology-American Society of Hematology Education Program
- GABA and Glutamate Transporters in Brain
- (2013) Yun Zhou et al. Frontiers in Endocrinology
- The Glutamate–Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation
- (2013) Leif Hertz Frontiers in Endocrinology
- The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease
- (2013) Animesh Raha et al. Acta Neuropathologica Communications
- Inappropriately chelated iron in the cerebrospinal fluid of amyotrophic lateral sclerosis patients
- (2012) Aleksandar Ignjatović et al. Amyotrophic Lateral Sclerosis
- Oxidative DNA Damage and Nucleotide Excision Repair
- (2012) Joost P.M. Melis et al. ANTIOXIDANTS & REDOX SIGNALING
- The Protective Effects of Riluzole on Manganese-Induced Disruption of Glutamate Transporters and Glutamine Synthetase in the Cultured Astrocytes
- (2012) Yu Deng et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - searching for the connections
- (2012) Wojciech Danysz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Ironing Out Cell Death Mechanisms
- (2012) John C. Reed et al. CELL
- Iron homeostasis in astrocytes and microglia is differentially regulated by TNF-α and TGF-β1
- (2012) Khizr I. Rathore et al. GLIA
- Synaptic Released Zinc Promotes Tau Hyperphosphorylation by Inhibition of Protein Phosphatase 2A (PP2A)
- (2012) Xu-Ying Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Estrogen Attenuates Manganese-Induced Glutamate Transporter Impairment in Rat Primary Astrocytes
- (2012) Eunsook Lee et al. NEUROTOXICITY RESEARCH
- Human Exposure Pathways of Heavy Metals in a Lead-Zinc Mining Area, Jiangsu Province, China
- (2012) Chang-Sheng Qu et al. PLoS One
- Functional roles of transferrin in the brain
- (2011) Dominique F. Leitner et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Nitric oxide signaling: Classical, less classical, and nonclassical mechanisms
- (2011) Antonio Martínez-Ruiz et al. FREE RADICAL BIOLOGY AND MEDICINE
- HFE Gene Variants Affect Iron in the Brain
- (2011) Wint Nandar et al. JOURNAL OF NUTRITION
- Association between divalent metal transport 1 encoding gene (SLC11A2) and disease duration in amyotrophic lateral sclerosis
- (2011) Hélène Blasco et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Patterns of levels of biological metals in CSF differ among neurodegenerative diseases
- (2011) Isao Hozumi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Riluzole elevates GLT-1 activity and levels in striatal astrocytes
- (2011) Marica Carbone et al. NEUROCHEMISTRY INTERNATIONAL
- Effects of arsenite on glutamate metabolism in primary cultured astrocytes
- (2011) Fenghong Zhao et al. TOXICOLOGY IN VITRO
- Oxidative stress caused by mitochondrial calcium overload
- (2010) Tsung-I Peng et al. Annals of the New York Academy of Sciences
- Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux
- (2010) M.-B. Troadec et al. BLOOD
- Synergistic accumulation of iron and zinc by cultured astrocytes
- (2010) Glenda M. Bishop et al. JOURNAL OF NEURAL TRANSMISSION
- Altered microglial copper homeostasis in a mouse model of Alzheimer’s disease
- (2010) Zhiqiang Zheng et al. JOURNAL OF NEUROCHEMISTRY
- Plasma biomarkers associated with ALS and their relationship to iron homeostasis
- (2010) Ryan M. Mitchell et al. MUSCLE & NERVE
- Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice
- (2010) Huiying Gu et al. NEUROSCIENCE LETTERS
- Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia
- (2010) Glenda M. Bishop et al. NEUROTOXICITY RESEARCH
- Neuroglia in neurodegeneration
- (2009) Michael T. Heneka et al. BRAIN RESEARCH REVIEWS
- Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement
- (2009) Hyman M. Schipper et al. JOURNAL OF NEUROCHEMISTRY
- Metal Concentrations in Plasma and Cerebrospinal Fluid in Patients with Alzheimer’s Disease
- (2008) Lars Gerhardsson et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity
- (2008) Kryslaine O. Lopes et al. GLIA
- Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins
- (2008) Jun Wang et al. NEUROCHEMISTRY INTERNATIONAL
- Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks
- (2008) Kishore V. Kuchibhotla et al. NEURON
- Zinc at glutamatergic synapses
- (2008) P. Paoletti et al. NEUROSCIENCE
- Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease
- (2008) M. A. Busche et al. SCIENCE
- Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
- (2007) Andrew J. Farrall et al. NEUROBIOLOGY OF AGING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started