Mechanism of depression as a risk factor in the development of Alzheimer’s disease: the function of AQP4 and the glymphatic system

Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway

(2016) Sattar Ostadhadi et al.   BIOMEDICINE & PHARMACOTHERAPY

New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain

(2016) Poornima Venkat et al.   CROATIAN MEDICAL JOURNAL

Serotonergic Drugs: Agonists/Antagonists at Specific Serotonergic Subreceptors for the Treatment of Cognitive, Depressant and Psychotic Symptoms in Alzheimer's Disease

(2016) Felix-Martin Werner et al.   CURRENT PHARMACEUTICAL DESIGN

Leptin suppresses adenosine triphosphate-induced impairment of spinal cord astrocytes

(2016) Baoman Li et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Evidence for alterations of the glial syncytial function in major depressive disorder

(2016) Adriana Medina et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer’s disease

(2016) T Roostaei et al.   MOLECULAR PSYCHIATRY

Total Lignans of Schisandra chinensis Ameliorates Aβ1-42-Induced Neurodegeneration with Cognitive Impairment in Mice and Primary Mouse Neuronal Cells

(2016) Xu Zhao et al.   PLoS One

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

Geldanamycin Reduces Aβ-Associated Anxiety and Depression, Concurrent with Autophagy Provocation

(2015) Nayereh Zare et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Potential Roles of Aquaporin 4 in Alzheimer’s Disease

(2015) Yu-Long Lan et al.   MOLECULAR NEUROBIOLOGY

Resveratrol exerts anti-inflammatory and neuroprotective effects to prevent memory deficits in rats exposed to chronic unpredictable mild stress

(2015) Yusufhan Yazir et al.   PHYSIOLOGY & BEHAVIOR

Modeling the Role of the Glymphatic Pathway and Cerebral Blood Vessel Properties in Alzheimer’s Disease Pathogenesis

(2015) Christina Rose Kyrtsos et al.   PLoS One

Cell type-specific in vivo expression of genes encoding signalling molecules in the brain in response to chronic mild stress and chronic treatment with fluoxetine

(2015) Lu Dong et al.   PSYCHOPHARMACOLOGY

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

(2015) Iben Lundgaard et al.   Nature Communications

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

Impairment of paravascular clearance pathways in the aging brain

(2014) Benjamin T. Kress et al.   ANNALS OF NEUROLOGY

Fluoxetine and all other SSRIs are 5-HT2B Agonists - Importance for their Therapeutic Effects

(2014) Liang Peng et al.   Current Neuropharmacology

Reduced Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor Is Associated With Cognitive Impairment in Late-Life Major Depression

(2014) B. S. Diniz et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Bathing the brain

(2013) Warren J. Strittmatter   JOURNAL OF CLINICAL INVESTIGATION

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

(2013) Jeffrey J. Iliff et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO3a Involvement in the Release of TNF-α Stimulated by ATP in Spinal Cord Astrocytes

(2013) Maosheng Xia et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Immunotherapy against amyloid pathology in Alzheimer's disease

(2013) Daniela Galimberti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

(2013) Lijun Yang et al.   Journal of Translational Medicine

The Inside-Out Amyloid Hypothesis and Synapse Pathology in Alzheimer's Disease

(2013) Gunnar K. Gouras et al.   Neurodegenerative Diseases

Chronic ceftriaxone treatment rescues hippocampal memory deficit in AQP4 knockout mice via activation of GLT-1

(2013) Jun Yang et al.   NEUROPHARMACOLOGY

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Is There a Cerebral Lymphatic System?

(2013) J. J. Iliff et al.   STROKE

Lower CSF Amyloid Beta Peptides and Higher F2-Isoprostanes in Cognitively Intact Elderly Individuals With Major Depressive Disorder

(2012) Nunzio Pomara et al.   AMERICAN JOURNAL OF PSYCHIATRY

Cell Type-Specific Gene Expression and Editing Responses to Chronic Fluoxetine Treatment in the In Vivo Mouse Brain and Their Relevance for Stress-Induced Anhedonia

(2012) Baoman Li et al.   NEUROCHEMICAL RESEARCH

Contributions in astrocytes of SMIT1/2 and HMIT to myo-inositol uptake at different concentrations and pH

(2012) Hui Fu et al.   NEUROCHEMISTRY INTERNATIONAL

Aquaporin-4 Deficiency Impairs Synaptic Plasticity and Associative Fear Memory in the Lateral Amygdala: Involvement of Downregulation of Glutamate Transporter-1 Expression

(2012) Yan-Kun Li et al.   NEUROPSYCHOPHARMACOLOGY

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

(2012) Cheryl A. Hawkes et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Fluoxetine affects GluK2 editing, glutamate-evoked Ca2+ influx and extracellular signal-regulated kinase phosphorylation in mouse astrocytes

(2011) Baoman Li   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

A review on animal models for screening potential anti-stress agents

(2011) Amteshwar Singh Jaggi et al.   NEUROLOGICAL SCIENCES

Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer’s disease neuropathology

(2010) Masakazu Hashimoto et al.   ACTA NEUROPATHOLOGICA

Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema

(2010) Hironaka Igarashi et al.   NEUROLOGICAL SCIENCES

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

History of depression, depressive symptoms, and medial temporal lobe atrophy and the risk of Alzheimer disease

(2008) M. I. Geerlings et al.   NEUROLOGY

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

(2008) Irving Kirsch et al.   PLOS MEDICINE