Farnesoid X receptor is an effective target for modulating lipid accumulation in grass carp, Ctenopharyngodon idella

Dietary bile acids regulate the hepatic lipid homeostasis in tiger puffer fed normal or high-lipid diets

(2020) Zhangbin Liao et al.   AQUACULTURE

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

(2020) Daqian Xu et al.   NATURE

Feeding Faba Beans (Vicia faba L.) Reduces Myocyte Metabolic Activity in Grass Carp (Ctenopharyngodon idellus)

(2020) Jing-jing Tian et al.   Frontiers in Physiology

Gut Microbiota and Energy Homeostasis in Fish

(2019) Robyn Lisa Butt et al.   Frontiers in Endocrinology

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

(2019) Baoguo Li et al.   Cell Reports

Lipid droplets participate in modulating innate immune genes in Ctenopharyngodon idella kidney cells

(2019) Cai-xia Lei et al.   FISH & SHELLFISH IMMUNOLOGY

A Human-like Bile Acid Pool Induced by Deletion of Cyp2c70 Modulates Effects of Farnesoid X Receptor Activation in Mice

(2019) Jan Freark de Boer et al.   JOURNAL OF LIPID RESEARCH

Molecular cloning and characterization of farnesoid X receptor from large yellow croaker ( Larimichthys crocea ) and the effect of dietary CDCA on the expression of inflammatory genes in intestine and spleen

(2018) Jianlong Du et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

G0S2a1 (G0/G1 switch gene 2a1) is downregulated by TNF-α in grass carp ( Ctenopharyngodon idellus ) hepatocytes through PPARα inhibition

(2018) Jian Sun et al.   GENE

Transcriptome analysis of grass carp provides insights into disease-related genes and novel regulation pattern of bile acid feedback in response to lithocholic acid

(2018) Fan Xiong et al.   AQUACULTURE

Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism

(2017) Preeti Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altenusin, a Nonsteroidal Microbial Metabolite, Attenuates Nonalcoholic Fatty Liver Disease by Activating the Farnesoid X Receptor

(2017) Zhihui Zheng et al.   MOLECULAR PHARMACOLOGY

An Intestinal Microbiota–Farnesoid X Receptor Axis Modulates Metabolic Disease

(2016) Frank J. Gonzalez et al.   GASTROENTEROLOGY

Microbiota-induced obesity requires farnesoid X receptor

(2016) Ava Parséus et al.   GUT

Major role of adipocyte prostaglandin E2in lipolysis-induced macrophage recruitment

(2016) Xiaoqian Hu et al.   JOURNAL OF LIPID RESEARCH

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

(2016) Madlen Matz-Soja et al.   eLife

Comparative analysis of the hepatopancreas transcriptome of grass carp (Ctenopharyngodon idellus) fed with lard oil and fish oil diets

(2015) Jing-Jing Tian et al.   GENE

Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity

(2015) Frank J. Gonzalez et al.   JOURNAL OF HEPATOLOGY

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

(2015) Changtao Jiang et al.   Nature Communications

Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis

(2014) Yang Jiao et al.   ACTA PHARMACOLOGICA SINICA

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Knocking on FXR's Door:The "Hammerhead"-Structure Series of FXRs Agonists - Amphiphilic Isoxazoles with Potent In Vitro and In Vivo Activities

(2014) Christian Gege et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Beyond intestinal soap—bile acids in metabolic control

(2014) Folkert Kuipers et al.   Nature Reviews Endocrinology

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

(2013) Fei Li et al.   Nature Communications

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

(2011) J. Prawitt et al.   DIABETES

Cytochrome P450s in the synthesis of cholesterol and bile acids - from mouse models to human diseases

(2011) Gregor Lorbek et al.   FEBS Journal

Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro☆

(2010) Deanna L. Howarth et al.   AQUATIC TOXICOLOGY

The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase

(2010) Xingyuan Yang et al.   Cell Metabolism

The ARF-Like GTPase ARFRP1 Is Essential for Lipid Droplet Growth and Is Involved in the Regulation of Lipolysis

(2009) A. Hommel et al.   MOLECULAR AND CELLULAR BIOLOGY

Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes

(2008) Sandrine P Claus et al.   Molecular Systems Biology