Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis
出版年份 2016 全文链接
标题
Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis
作者
关键词
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出版物
eLife
Volume 5, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2016-05-17
DOI
10.7554/elife.13308
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Computational prediction and experimental validation of novel Hedgehog-responsive enhancers linked to genes of the Hedgehog pathway
- (2016) Katherine Gurdziel et al. BMC DEVELOPMENTAL BIOLOGY
- RNAi in murine hepatocytes: the agony of choice—a study of the influence of lipid-based transfection reagents on hepatocyte metabolism
- (2015) Jan Böttger et al. ARCHIVES OF TOXICOLOGY
- Zonation of hepatic fatty acid metabolism — The diversity of its regulation and the benefit of modeling
- (2015) J. Schleicher et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes
- (2015) Aijaz Ahmed et al. Clinical Gastroenterology and Hepatology
- β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis
- (2015) Satdarshan Pal Monga GASTROENTEROLOGY
- Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes
- (2015) Wolfgang Schmidt-Heck et al. Molecular BioSystems
- Targeting GLI factors to inhibit the Hedgehog pathway
- (2015) Paola Infante et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Liver fibrosis markers of nonalcoholic steatohepatitis
- (2015) Hirayuki Enomoto WORLD JOURNAL OF GASTROENTEROLOGY
- Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis
- (2015) Paola Dongiovanni et al. Biomed Research International
- The genetic architecture of NAFLD among inbred strains of mice
- (2015) Simon T Hui et al. eLife
- Non-Canonical Hh Signaling in Cancer—Current Understanding and Future Directions
- (2015) Dongsheng Gu et al. Cancers
- Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels
- (2014) Madlen Matz-Soja et al. Cell Communication and Signaling
- Pnpla3I148Mknockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
- (2014) Eriks Smagris et al. HEPATOLOGY
- Bindings of ChREBP and SREBP1, and Histone Acetylation around the Rat Liver Fatty Acid Synthase Gene Are Associated with Induction of the Gene during the Suckling-Weaning Transition
- (2014) Saho MORISHITA et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Canonical and non-canonical Hedgehog signalling and the control of metabolism
- (2014) Raffaele Teperino et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Liver zonation: Novel aspects of its regulation and its impact on homeostasis
- (2014) Rolf Gebhardt WORLD JOURNAL OF GASTROENTEROLOGY
- Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models
- (2014) Chidambaram Ramanathan et al. PLoS Genetics
- Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation
- (2014) Jenny D.Y. Chow et al. Molecular Metabolism
- Activity Increase in Respiratory Chain Complexes by Rubella Virus with Marginal Induction of Oxidative Stress
- (2013) C. Claus et al. JOURNAL OF VIROLOGY
- Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis
- (2012) Jay V. Patankar et al. JOURNAL OF HEPATOLOGY
- Evaluation of Fbxw7 expression and its correlation with expression of SREBP-1 in a mouse model of NAFLD
- (2012) KANGSHENG TU et al. Molecular Medicine Reports
- Antagonistic and Cooperative Actions of Kif7 and Sufu Define Graded Intracellular Gli Activities in Hedgehog Signaling
- (2012) Kelvin King Lo Law et al. PLoS One
- Update on Ppar and Nonalcoholic Fatty Liver Disease
- (2012) Gene P. Ables PPAR Research
- Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis
- (2011) Michiko Itoh et al. AMERICAN JOURNAL OF PATHOLOGY
- MotifMap: integrative genome-wide maps of regulatory motif sites for model species
- (2011) Kenneth Daily et al. BMC BIOINFORMATICS
- Reconstruction and crosstalk of protein–protein interaction networks of Wnt and Hedgehog signaling in Drosophila melanogaster
- (2011) Aysun Eren Toku et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet
- (2011) Viviane Trak-Smayra et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Signals from dying hepatocytes trigger growth of liver progenitors
- (2010) Y. Jung et al. GUT
- Hedgehog signaling in the liver
- (2010) Alessia Omenetti et al. JOURNAL OF HEPATOLOGY
- Relationships Between IGF-1 and IGFBP-1 and Adiposity in Obese African-American and Latino Adolescents
- (2010) Tanya L. Alderete et al. Obesity
- Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals
- (2010) B. Stecca et al. Journal of Molecular Cell Biology
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- Organ patterning in the adult stage: The role of Wnt/β-catenin signaling in liver zonation and beyond
- (2009) Rolf Gebhardt et al. DEVELOPMENTAL DYNAMICS
- Association between hepatic steatosis and serum IGF1 and IGFBP-3 levels in a population-based sample
- (2009) Henry Völzke et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
- (2009) Elisa Fabbrini et al. HEPATOLOGY
- Heterogeneous expression of suppressor of cytokine signalling 2 (SOCS-2) in liver tissue
- (2009) Sebastian Zellmer et al. JOURNAL OF ANATOMY
- 4-Aminoethylamino-emodin - a novel potent inhibitor of GSK-3β- acts as an insulin-sensitizer avoiding downstream effects of activated β-catenin
- (2009) Rolf Gebhardt et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- From Teratogens to Potential Therapeutics: Natural Inhibitors of the Hedgehog Signaling Network Come of Age
- (2009) Amalya Hovhannisyan et al. PLANTA MEDICA
- Proteomic analysis of β-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway
- (2009) Philippe Chafey et al. PROTEOMICS
- Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice
- (2009) Mara Sandrock et al. Reproductive Biology and Endocrinology
- Functional analysis of rat liver citrate carrier promoter: differential responsiveness to polyunsaturated fatty acids
- (2008) Fabrizio Damiano et al. BIOCHEMICAL JOURNAL
- Exploration of Human ORFeome: High-Throughput Preparation of ORF Clones and Efficient Characterization of Their Protein Products
- (2008) T. Nagase et al. DNA RESEARCH
- Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
- (2008) Catherine Postic et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
- (2008) Stefano Romeo et al. NATURE GENETICS
- Primers on Molecular Pathways GLI: More than Just Hedgehog?
- (2008) Martín E. Fernández-Zapico PANCREATOLOGY
- Nonalcoholic fatty liver disease and mitochondrial dysfunction
- (2008) Yongzhong Wei et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes
- (2008) Brian D. Reed et al. PLoS Genetics
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