标题
Cancer Stemness: p53 at the Wheel
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-01-13
DOI
10.3389/fonc.2020.604124
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
- (2020) David S. Hong et al. BRITISH JOURNAL OF CANCER
- Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
- (2020) Luisa F. Escobar-Hoyos et al. CANCER CELL
- Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome
- (2020) Valeria Capaci et al. Nature Communications
- Metabolic Adaptations in Cancer Stem Cells
- (2020) Umesh Prasad Yadav et al. Frontiers in Oncology
- MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer
- (2019) Lu Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cancer Stem Cells and Radioresistance: DNA Repair and Beyond
- (2019) Alexander Schulz et al. Cancers
- P53-R273H mutation enhances colorectal cancer stemness through regulating specific lncRNAs
- (2019) Yuechao Zhao et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer
- (2019) Gu Xiao et al. CANCER RESEARCH
- Genome-Wide Small RNA Sequencing Identifies MicroRNAs Deregulated in Non-Small Cell Lung Carcinoma Harboring Gain-of-Function Mutant p53
- (2019) Arindam Datta et al. Genes
- WEE1 inhibitor, AZD1775, overcomes trastuzumab resistance by targeting cancer stem-like properties in HER2-positive breast cancer
- (2019) Andrea Sand et al. CANCER LETTERS
- TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma
- (2018) Alexander Jethwa et al. BLOOD
- Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells
- (2018) Huong Thuy Le et al. CANCER LETTERS
- New therapeutic strategies to treat human cancers expressing mutant p53 proteins
- (2018) Giovanni Blandino et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
- (2018) Hilla Solomon et al. ONCOGENE
- p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
- (2018) Sunetra Roy et al. eLife
- Targeting cancer stem cells and their niche: perspectives for future therapeutic targets and strategies
- (2018) Yue Zhao et al. SEMINARS IN CANCER BIOLOGY
- Mutant p53 as a guardian of the cancer cell
- (2018) Fiamma Mantovani et al. CELL DEATH AND DIFFERENTIATION
- PARP inhibition induces enrichment of DNA repair proficient CD133 and CD117 positive ovarian cancer stem cells
- (2018) Chiara Bellio et al. MOLECULAR CANCER RESEARCH
- Poly(ADP-Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer-Initiating Cells to Chemotherapy
- (2018) Awad Jarrar et al. STEM CELLS
- ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance
- (2017) Romana-Rea Begicevic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
- (2017) Kai Liu et al. MOLECULAR CELL
- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Mechanical cues control mutant p53 stability through a mevalonate–RhoA axis
- (2017) Eleonora Ingallina et al. NATURE CELL BIOLOGY
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others
- (2017) Kanaga Sabapathy et al. Nature Reviews Clinical Oncology
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mutant p53 oncogenic functions in cancer stem cells are regulated by WIP through YAP/TAZ
- (2017) M Escoll et al. ONCOGENE
- Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin
- (2017) Kang Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 switches off pluripotency on differentiation
- (2017) Tongxiang Lin et al. Stem Cell Research & Therapy
- Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells
- (2017) Jia Deng et al. PLoS One
- Novel targets and interaction partners of mutant p53 Gain-Of-Function
- (2016) Lydia Aschauer et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
- (2016) Darjus F. Tschaharganeh et al. CELL
- Targeting mutant p53 in cancer: a long road to precision therapy
- (2016) Fiamma Mantovani et al. FEBS Journal
- E2 Ubiquitin-conjugating Enzyme,UBE2CGene, Is Reciprocally Regulated by Wild-type and Gain-of-Function Mutant p53
- (2016) Swati Bajaj et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer stem cells
- (2016) Jeremy N. Rich MEDICINE
- Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition
- (2016) Marco Cordani et al. Molecular Oncology
- Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
- (2016) Dawid Walerych et al. NATURE CELL BIOLOGY
- Differential regulated microRNA by wild type and mutant p53 in induced pluripotent stem cells
- (2016) Francesca Grespi et al. Cell Death & Disease
- Cisplatin induces stemness in ovarian cancer
- (2016) Andrew Wiechert et al. Oncotarget
- The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
- (2016) Jiandong Chen Cold Spring Harbor Perspectives in Medicine
- Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
- (2016) Wanyin Chen et al. Stem Cells International
- A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis
- (2016) Xuetian Yue et al. Cell Discovery
- Oncogenic Intra-p53 Family Member Interactions in Human Cancers
- (2016) Maria Ferraiuolo et al. Frontiers in Oncology
- Cellular Homeostasis and Repair in the Mammalian Liver
- (2015) Ben Z. Stanger Annual Review of Physiology
- Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine
- (2015) Claudia Fiorini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Novel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells
- (2015) Samaya R. Krishnan et al. BREAST CANCER RESEARCH AND TREATMENT
- TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma
- (2015) Naoki Oshimori et al. CELL
- DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53
- (2015) S K Alam et al. CELL DEATH AND DIFFERENTIATION
- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity
- (2015) S. K. Singh et al. EMBO JOURNAL
- Harnessing the apoptotic programs in cancer stem-like cells
- (2015) Y.-H. Wang et al. EMBO REPORTS
- YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins
- (2015) Silvia Di Agostino et al. EMBO REPORTS
- The Hippo transducer TAZ promotes epithelial to mesenchymal transition and cancer stem cell maintenance in oral cancer
- (2015) Zhongwu Li et al. Molecular Oncology
- Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment
- (2015) E. M. Alexandrova et al. NATURE
- Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer
- (2015) Shuo Wei et al. NATURE MEDICINE
- Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4
- (2015) Alla Polotskaia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells
- (2015) Yunlong He et al. STEM CELLS
- Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53
- (2015) E K Park et al. Cell Death & Disease
- Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities
- (2015) Madhusudhan Kollareddy et al. Nature Communications
- BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function
- (2015) Xuetian Yue et al. eLife
- The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
- (2015) Nikola Arsic et al. Stem Cell Reports
- Regulation of Mutant p53 Protein Expression
- (2015) Reshma Vijayakumaran et al. Frontiers in Oncology
- Targeting Mutant p53 by a SIRT1 Activator YK-3-237 Inhibits the Proliferation of Triple-Negative Breast Cancer Cells
- (2015) Yong Weon Yi et al. Oncotarget
- SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.
- (2015) Vamsi K. Kolukula et al. Oncotarget
- Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression
- (2015) Fabio Valenti et al. Oncotarget
- Loss of p53 Induces Tumorigenesis in p21-Deficient Mesenchymal Stem Cells
- (2015) Rene Rodriguez et al. NEOPLASIA
- A Novel PTEN/Mutant p53/c-Myc/Bcl-XL Axis Mediates Context-Dependent Oncogenic Effects of PTEN with Implications for Cancer Prognosis and Therapy
- (2015) Xiaoping Huang et al. NEOPLASIA
- Interaction of mutant p53 with p73: A Surface Plasmon Resonance and Atomic Force Spectroscopy study
- (2014) Simona Santini et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
- (2014) Patricia A.J. Muller et al. CANCER CELL
- Gain-of-function of mutant p53: mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells
- (2014) Amjad Ali et al. CANCER LETTERS
- Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling
- (2014) Susann Weissmueller et al. CELL
- The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele
- (2014) Y Shetzer et al. CELL DEATH AND DIFFERENTIATION
- The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
- (2014) Xichen Bao et al. CELL RESEARCH
- Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer
- (2014) M. Sonego et al. EMBO Molecular Medicine
- p53: The barrier to cancer stem cell formation
- (2014) Ronit Aloni-Grinstein et al. FEBS LETTERS
- DifferentTP53mutations are associated with specific chromosomal rearrangements, telomere length changes, and remodeling of the nuclear architecture of telomeres
- (2014) Oumar Samassekou et al. GENES CHROMOSOMES & CANCER
- Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis
- (2014) Antti Arjonen et al. JOURNAL OF CLINICAL INVESTIGATION
- Long-lived intestinal tuft cells serve as colon cancer–initiating cells
- (2014) C. Benedikt Westphalen et al. JOURNAL OF CLINICAL INVESTIGATION
- Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation
- (2014) Ge Zhou et al. MOLECULAR CELL
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- Tackling the cancer stem cells — what challenges do they pose?
- (2014) Diwakar R. Pattabiraman et al. NATURE REVIEWS DRUG DISCOVERY
- A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy
- (2014) C. Liu et al. NUCLEIC ACIDS RESEARCH
- Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist
- (2014) V Ubertini et al. ONCOGENE
- A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis
- (2014) M Subramanian et al. ONCOGENE
- Pla2g16 phospholipase mediates gain-of-function activities of mutant p53
- (2014) S. Xiong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A gain-of-function mutant p53–HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress
- (2014) D Li et al. Cell Death & Disease
- Gain of Function of Mutant TP53 in Glioblastoma: Prognosis and Response to Temozolomide
- (2013) Xiang Wang et al. ANNALS OF SURGICAL ONCOLOGY
- Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer
- (2013) Tomer Cooks et al. CANCER CELL
- Inflammation and cancer stem cells
- (2013) Sarah Shigdar et al. CANCER LETTERS
- Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast
- (2013) Alessandra Rustighi et al. EMBO Molecular Medicine
- Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR-145
- (2013) DONG REN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Mutant p53 Regulates Dicer through p63-dependent and -independent Mechanisms to Promote an Invasive Phenotype
- (2013) Patricia A. J. Muller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Id4 dependent acetylation restores mutant-p53 transcriptional activity
- (2013) Ashley E Knowell et al. Molecular Cancer
- Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche
- (2013) Andrea Flesken-Nikitin et al. NATURE
- First microRNA mimic enters clinic
- (2013) Aaron Bouchie NATURE BIOTECHNOLOGY
- Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells
- (2013) Kadir C. Akdemir et al. NUCLEIC ACIDS RESEARCH
- Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells
- (2013) S Masciarelli et al. ONCOGENE
- MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells
- (2013) P Ceppi et al. ONCOGENE
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
- (2013) M. A. Nieto SCIENCE
- Oct4 Maintains the Pluripotency of Human Embryonic Stem Cells by Inactivating p53 Through Sirt1-Mediated Deacetylation
- (2013) Zhen-Ning Zhang et al. STEM CELLS
- Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression
- (2013) W Wang et al. Cell Death & Disease
- The p53–PUMA axis suppresses iPSC generation
- (2013) Yanxin Li et al. Nature Communications
- Differential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells
- (2013) Amjad Ali et al. Nature Communications
- Tumour-associated mutant p53 drives the Warburg effect
- (2013) Cen Zhang et al. Nature Communications
- Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53
- (2012) Lorna Jane Warnock et al. CANCER BIOLOGY & THERAPY
- Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
- (2012) Oscar H. Ocaña et al. CANCER CELL
- Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
- (2012) William A. Freed-Pastor et al. CELL
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop
- (2012) Fabio Valenti et al. CELL CYCLE
- Dietary downregulation of mutant p53 levels via glucose restriction
- (2012) Olga Catalina Rodriguez et al. CELL CYCLE
- Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling
- (2012) Dung-Fang Lee et al. Cell Stem Cell
- Cancer Stem Cells: Current Status and Evolving Complexities
- (2012) Jane E. Visvader et al. Cell Stem Cell
- Therapeutic targeting of the p53 pathway in cancer stem cells
- (2012) Varun V Prabhu et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Mutant p53: one name, many proteins
- (2012) W. A. Freed-Pastor et al. GENES & DEVELOPMENT
- Mammary Epithelial Cell Polarity Is Regulated Differentially by p73 Isoforms via Epithelial-to-mesenchymal Transition
- (2012) Yanhong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutant p53R273Hattenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species
- (2012) Eyal Kalo et al. JOURNAL OF CELL SCIENCE
- A restricted cell population propagates glioblastoma growth after chemotherapy
- (2012) Jian Chen et al. NATURE
- Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion
- (2012) P A J Muller et al. ONCOGENE
- Mutant p53 drives invasion in breast tumors through up-regulation of miR-155
- (2012) P M Neilsen et al. ONCOGENE
- Mutant p53 gain-of-function induces epithelial–mesenchymal transition through modulation of the miR-130b–ZEB1 axis
- (2012) P Dong et al. ONCOGENE
- Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer
- (2012) P. Tucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53-Facilitated miR-199a-3p Regulates Somatic Cell Reprogramming
- (2012) Jiaxu Wang et al. STEM CELLS
- Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
- (2012) Michael N. Pollak Cancer Discovery
- p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells
- (2012) Abhinav K. Jain et al. PLOS BIOLOGY
- Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells
- (2011) Jai-Hee Moon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer
- (2011) Javier E. Girardini et al. CANCER CELL
- Multiple Stress Signals Activate Mutant p53 In Vivo
- (2011) Y.-A. Suh et al. CANCER RESEARCH
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells
- (2011) Andreia V. Pinho et al. CELL CYCLE
- MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
- (2011) S Donzelli et al. CELL DEATH AND DIFFERENTIATION
- Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy
- (2011) W-J Lu et al. CELL DEATH AND DIFFERENTIATION
- SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
- (2011) D Li et al. CELL DEATH AND DIFFERENTIATION
- WEE1 Kinase Targeting Combined with DNA-Damaging Cancer Therapy Catalyzes Mitotic Catastrophe
- (2011) P. C. De Witt Hamer et al. CLINICAL CANCER RESEARCH
- Cancer stem cells and angiogenesis
- (2011) Yue Zhao et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Broader utilization of origins of DNA replication in cancer cell lines along a 78 kb region of human chromosome 2q34
- (2011) Manuel S. Valenzuela et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Links between mutant p53 and genomic instability
- (2011) Walter Hanel et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells
- (2011) D. Li et al. MOLECULAR CANCER RESEARCH
- p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs
- (2011) Chun-Ju Chang et al. NATURE CELL BIOLOGY
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- The cancer stem cell: premises, promises and challenges
- (2011) Hans Clevers NATURE MEDICINE
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73
- (2010) Chao Lu et al. CANCER BIOLOGY & THERAPY
- Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
- (2010) Hugo J. Snippert et al. CELL
- A MicroRNA Targeting Dicer for Metastasis Control
- (2010) Graziano Martello et al. CELL
- Hedgehog controls neural stem cells through p53-independent regulation of Nanog
- (2010) Agnese Po et al. EMBO JOURNAL
- NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
- (2010) Marie Zbinden et al. EMBO JOURNAL
- p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
- (2010) Z. Zhao et al. GENES & DEVELOPMENT
- 40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
- (2010) E. Ungewitter et al. GENES & DEVELOPMENT
- Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
- (2010) Rachel Sarig et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selective activation of p53-mediated tumour suppression in high-grade tumours
- (2010) Melissa R. Junttila et al. NATURE
- Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
- (2010) H. Mizuno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
- (2010) C. Lopez-Garcia et al. SCIENCE
- Repression of Mammary Stem/Progenitor Cells by p53 Is Mediated by Notch and Separable from Apoptotic Activity
- (2010) Luwei Tao et al. STEM CELLS
- p53 and stem cells: new developments and new concerns
- (2010) Tongbiao Zhao et al. TRENDS IN CELL BIOLOGY
- The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells
- (2009) Angelo Cicalese et al. CELL
- A Fresh Look at iPS Cells
- (2009) Shinya Yamanaka CELL
- Mutant p53 Drives Invasion by Promoting Integrin Recycling
- (2009) Patricia A.J. Muller et al. CELL
- A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis
- (2009) Maddalena Adorno et al. CELL
- Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
- (2009) Yohei Shimono et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
- (2009) Barbara Stecca et al. EMBO JOURNAL
- p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells
- (2009) Alejandro Armesilla-Diaz et al. EXPERIMENTAL CELL RESEARCH
- The promises and perils of p53
- (2009) Valery Krizhanovsky et al. NATURE
- Linking the p53 tumour suppressor pathway to somatic cell reprogramming
- (2009) Teruhisa Kawamura et al. NATURE
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- (2009) Rosa M. Marión et al. NATURE
- Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
- (2009) Hyenjong Hong et al. NATURE
- The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
- (2009) Giulia Fontemaggi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
- (2009) Qing Ji et al. PLoS One
- A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells
- (2009) K.-H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant p53 Gain-of-Function in Cancer
- (2009) M. Oren et al. Cold Spring Harbor Perspectives in Biology
- Clinical Outcomes and Correlates of TP53 Mutations and Cancer
- (2009) A. I. Robles et al. Cold Spring Harbor Perspectives in Biology
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway
- (2008) N.V. Khromova et al. CANCER LETTERS
- Peptide Aptamers Targeting Mutant p53 Induce Apoptosis in Tumor Cells
- (2008) E. Guida et al. CANCER RESEARCH
- Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
- (2008) Samuel Godar et al. CELL
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Mre11 Nuclease Activity Has Essential Roles in DNA Repair and Genomic Stability Distinct from ATM Activation
- (2008) Jeffrey Buis et al. CELL
- SIRT1 Regulates Apoptosis and Nanog Expression in Mouse Embryonic Stem Cells by Controlling p53 Subcellular Localization
- (2008) Myung-Kwan Han et al. Cell Stem Cell
- Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation
- (2008) Yang Zhao et al. Cell Stem Cell
- Bmi1 Regulates Stem Cells and Proliferation and Differentiation of Committed Cells in Mammary Epithelium
- (2008) Alexandra M. Pietersen et al. CURRENT BIOLOGY
- A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
- (2008) Ulrike Burk et al. EMBO REPORTS
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss
- (2008) T. Terzian et al. GENES & DEVELOPMENT
- The cancer stem cell hypothesis: in search of definitions, markers and relevance
- (2008) Michail Shipitsin et al. LABORATORY INVESTIGATION
- A Gene Signature-Based Approach Identifies mTOR as a Regulator of p73
- (2008) J. M. Rosenbluth et al. MOLECULAR AND CELLULAR BIOLOGY
- NUMB controls p53 tumour suppressor activity
- (2008) Ivan N. Colaluca et al. NATURE
- p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
- (2008) Hongwu Zheng et al. NATURE
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- p53 regulates the self-renewal and differentiation of neural precursors
- (2008) A. Armesilla-Diaz et al. NEUROSCIENCE
- Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
- (2008) A. Restle et al. NUCLEIC ACIDS RESEARCH
- Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells
- (2008) T Maimets et al. ONCOGENE
- Chaperone-dependent stabilization and degradation of p53 mutants
- (2008) P Muller et al. ONCOGENE
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
- p53 Plays a Role in Mesenchymal Differentiation Programs, in a Cell Fate Dependent Manner
- (2008) Alina Molchadsky et al. PLoS One
- Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway
- (2008) J. E. Kravchenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 is required for etoposide-induced apoptosis of human embryonic stem cells
- (2007) C. Grandela et al. Stem Cell Research
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