The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C
出版年份 2020 全文链接
标题
The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C
作者
关键词
-
出版物
Frontiers in Microbiology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-12-14
DOI
10.3389/fmicb.2020.615965
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Co-circulation of coxsackieviruses A-6, A-10, and A-16 causes hand, foot, and mouth disease in Guangzhou city, China
- (2020) Jia Xie et al. BMC INFECTIOUS DISEASES
- Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors
- (2020) Roberto Manganaro et al. ANTIVIRAL RESEARCH
- The Heat Shock Protein 70 Family of Chaperones Regulates All Phases of the Enterovirus A71 Life Cycle
- (2020) Yu-Siang Su et al. Frontiers in Microbiology
- Pharmacological Characterization of the Mechanism of Action of R523062, a Promising Antiviral for Enterovirus D68
- (2020) Chunlong Ma et al. ACS Infectious Diseases
- Identification of dibucaine derivatives as novel potent enterovirus 2C helicase inhibitors: In vitro, in vivo, and combination therapy study
- (2020) Qi Tang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Foot-and-mouth disease virus antagonizes NOD2-mediated antiviral effects by inhibition of NOD2 protein expression
- (2019) Huisheng Liu et al. JOURNAL OF VIROLOGY
- Discovery of quinoline analogs as potent antivirals against enterovirus D68 (EV-D68)
- (2019) Rami Musharrafieh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ebola virus VP35 has novel NTPase and helicase-like activities
- (2019) Ting Shu et al. NUCLEIC ACIDS RESEARCH
- Elucidating the Host Interactome of EV-A71 2C Reveals Viral Dependency Factors
- (2019) Ye Li et al. Frontiers in Microbiology
- Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner
- (2019) Lisa Bauer et al. ACS Infectious Diseases
- Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I
- (2019) Wei Wen et al. VIROLOGY
- Emerging recombination of the C2 sub-genotype of HFMD-associated CV-A4 is persistently and extensively circulating in China
- (2019) Tianjiao Ji et al. Scientific Reports
- Divergent Pathogenic Properties of Circulating Coxsackievirus A6 Associated with Emerging Hand, Foot, and Mouth Disease
- (2018) Shao-Hua Wang et al. JOURNAL OF VIROLOGY
- Epidemiological surveillance of hand, foot and mouth disease in Shanghai in 2014–2016, prior to the introduction of the enterovirus 71 vaccine
- (2018) Jingjing Li et al. Emerging Microbes & Infections
- Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G
- (2018) Zhaolong Li et al. NUCLEIC ACIDS RESEARCH
- Crystal structure of a soluble fragment of poliovirus 2CATPase
- (2018) Hongxin Guan et al. PLoS Pathogens
- Encephalomyocarditis virus 2C protein antagonizes interferon-β signaling pathway through interaction with MDA5
- (2018) Liang Li et al. ANTIVIRAL RESEARCH
- Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein
- (2018) Chunyu Wei et al. Viruses-Basel
- Innate Immunity Evasion by Enteroviruses Linked to Epidemic Hand-Foot-Mouth Disease
- (2018) Yuefei Jin et al. Frontiers in Microbiology
- ICTV Virus Taxonomy Profile: Picornaviridae
- (2017) R. Zell et al. JOURNAL OF GENERAL VIROLOGY
- Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities
- (2017) Teng-Feng Li et al. JOURNAL OF VIROLOGY
- 2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation
- (2017) Jeffrey Lai et al. Viruses-Basel
- Direct-acting antivirals and host-targeting strategies to combat enterovirus infections
- (2017) Lisa Bauer et al. Current Opinion in Virology
- Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication
- (2017) Tao Wang et al. PLoS Pathogens
- Crystal structure of 2C helicase from enterovirus 71
- (2017) Hongxin Guan et al. Science Advances
- Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C
- (2016) Rachel Ulferts et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPaseCauses Conditional Defects in Encapsidation and Uncoating
- (2016) Emmanuel Asare et al. JOURNAL OF VIROLOGY
- Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator
- (2016) Zhigang Yi et al. JOURNAL OF VIROLOGY
- 2C Proteins of Enteroviruses Suppress IKKβ Phosphorylation by Recruiting Protein Phosphatase 1
- (2016) Qian Li et al. JOURNAL OF VIROLOGY
- Treatment of Chronic Enterovirus Encephalitis With Fluoxetine in a Patient With X-Linked Agammaglobulinemia
- (2016) Jacqueline Gofshteyn et al. PEDIATRIC NEUROLOGY
- SNARE-mediated membrane fusion in autophagy
- (2016) Yongyao Wang et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
- (2016) Kan Xing Wu et al. Nature Communications
- Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-β signaling pathway
- (2016) Dan Li et al. Scientific Reports
- Enterovirus 71 2C Protein Inhibits NF-κB Activation by Binding to RelA(p65)
- (2015) Haiwei Du et al. Scientific Reports
- Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone
- (2015) Hongjie Xia et al. PLoS Pathogens
- RNA chaperones encoded by RNA viruses
- (2015) Jie Yang et al. VIROLOGICA SINICA
- Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation inDrosophila
- (2015) Elena Morelli et al. Autophagy
- Coxsackievirus A16 Elicits Incomplete Autophagy Involving the mTOR and ERK Pathways
- (2015) Yingying Shi et al. PLoS One
- An evolving arsenal: viral RNA detection by RIG-I-like receptors
- (2014) Megan E Fitzgerald et al. CURRENT OPINION IN MICROBIOLOGY
- A C-terminal, cysteine-rich site in poliovirus 2CATPase is required for morphogenesis
- (2014) C. Wang et al. JOURNAL OF GENERAL VIROLOGY
- Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
- (2014) Delphine Goubau et al. NATURE
- Nonstructural proteins 2C and 3D are involved in autophagy as induced by the encephalomyocarditis virus
- (2014) Lei Hou et al. Virology Journal
- Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C
- (2013) Rachel Ulferts et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Biological activities of guanidine compounds, 2008 – 2012 update
- (2013) Franciszek Sączewski et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- The expanding role of NLRs in antiviral immunity
- (2013) Christopher Lupfer et al. IMMUNOLOGICAL REVIEWS
- Emergence, Circulation, and Spatiotemporal Phylogenetic Analysis of Coxsackievirus A6- and Coxsackievirus A10-Associated Hand, Foot, and Mouth Disease Infections from 2008 to 2012 in Shenzhen, China
- (2013) Ya-Qing He et al. JOURNAL OF CLINICAL MICROBIOLOGY
- The Nonstructural Protein 2C of a Picorna-Like Virus Displays Nucleic Acid Helix Destabilizing Activity That Can Be Functionally Separated from Its ATPase Activity
- (2013) Z. Cheng et al. JOURNAL OF VIROLOGY
- The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
- (2012) Eisuke Itakura et al. CELL
- Alanine Scanning of Poliovirus 2CATPaseReveals New Genetic Evidence that Capsid Protein/2CATPaseInteractions Are Essential for Morphogenesis
- (2012) Chunling Wang et al. JOURNAL OF VIROLOGY
- Foot-and-Mouth Disease Virus Nonstructural Protein 2C Interacts with Beclin1, Modulating Virus Replication
- (2012) D. P. Gladue et al. JOURNAL OF VIROLOGY
- Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection
- (2012) M. Arita et al. JOURNAL OF VIROLOGY
- COPI Is Required for Enterovirus 71 Replication
- (2012) Jianmin Wang et al. PLoS One
- Selection and characterisation of guanidine-resistant mutants of human enterovirus 71
- (2012) Sara Sadeghipour et al. VIRUS RESEARCH
- Picornavirus non-structural proteins as targets for new anti-virals with broad activity
- (2011) Heléne Norder et al. ANTIVIRAL RESEARCH
- Enterovirus 71 2C Protein Inhibits TNF- -Mediated Activation of NF- B by Suppressing I B Kinase Phosphorylation
- (2011) Z. Zheng et al. JOURNAL OF IMMUNOLOGY
- Host Factors in Enterovirus 71 Replication
- (2011) S.-R. Shih et al. JOURNAL OF VIROLOGY
- Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
- (2011) Roland Züst et al. NATURE IMMUNOLOGY
- RNA remodeling by chaperones and helicases
- (2011) Karin Musier-Forsyth RNA Biology
- Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine
- (2011) Martin Stangel et al. Neuropsychiatric Disease and Treatment
- Expanding knowledge of P3 proteins in the poliovirus lifecycle
- (2010) Craig E Cameron et al. Future Microbiology
- Foot-and-mouth disease virus utilizes an autophagic pathway during viral replication
- (2010) Vivian O'Donnell et al. VIROLOGY
- Direct Interaction between Two Viral Proteins, the Nonstructural Protein 2CATPase and the Capsid Protein VP3, Is Required for Enterovirus Morphogenesis
- (2010) Ying Liu et al. PLoS Pathogens
- Bridging IRES elements in mRNAs to the eukaryotic translation apparatus
- (2009) Kerry D. Fitzgerald et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Biological activities of guanidine compounds
- (2009) Franciszek Saczewski et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Innate immunity
- (2009) Stuart E. Turvey et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Enterovirus 71-induced autophagy detected in vitro and in vivo promotes viral replication
- (2009) Shu-Chen Huang et al. JOURNAL OF MEDICAL VIROLOGY
- Structural Mechanism of RNA Recognition by the RIG-I-like Receptors
- (2008) Mitsutoshi Yoneyama et al. IMMUNITY
- Innate immunity to virus infection
- (2008) Osamu Takeuchi et al. IMMUNOLOGICAL REVIEWS
- Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
- (2008) Hiroki Kato et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity
- (2008) M. Arita et al. JOURNAL OF GENERAL VIROLOGY
- The Thiazolobenzimidazole TBZE-029 Inhibits Enterovirus Replication by Targeting a Short Region Immediately Downstream from Motif C in the Nonstructural Protein 2C
- (2008) A. M. De Palma et al. JOURNAL OF VIROLOGY
- Selective inhibitors of picornavirus replication
- (2008) Armando M. De Palma et al. MEDICINAL RESEARCH REVIEWS
- The structure–function relationship of the enterovirus 3′-UTR
- (2008) Jan Zoll et al. VIRUS RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started