Biological activities of guanidine compounds

Carrier PNA for shRNA delivery into cells

(2009) Mizuki Kitamatsu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens

(2009) Hiroaki Gouda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of novel substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors

(2009) Wen-Ting Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure−Activity Study of Pentamidine Analogues as Antiprotozoal Agents

(2009) Svetlana M. Bakunova et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor

(2008) Andrew L. LaFrate et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–activity relationships of lipopolysaccharide sequestration in guanylhydrazone-bearing lipopolyamines

(2008) Wenyan Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum–acridines

(2008) Zhidong Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Serotonin Receptors

(2008) David E. Nichols et al.   CHEMICAL REVIEWS

BACE1 Structure and Function in Health and Alzheimers Disease

(2008) Sarah Cole et al.   Current Alzheimer Research

Basicity of Guanidines with Heteroalkyl Side Chains in Acetonitrile

(2008) Mirjana Eckert-Maksić et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

NG-Aminoguanidines from Primary Amines and the Preparation of Nitric Oxide Synthase Inhibitors

(2008) Nathaniel I. Martin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Substituted Aminoalkylguanidines as Potential Antihyperglycemic and Food Intake-Reducing Agents

(2008) Emanuela Tassoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acylguanidines as Bioisosteres of Guanidines:NG-Acylated Imidazolylpropylguanidines, a New Class of Histamine H2Receptor Agonists

(2008) Prasanta Ghorai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthetic Antimicrobial Peptidomimetics with Therapeutic Potential

(2008) Bengt Erik Haug et al.   JOURNAL OF MEDICINAL CHEMISTRY

Peptoidic Amino- and Guanidinium-Carrier Systems: Targeted Drug Delivery into the Cell Cytosol or the Nucleus

(2008) Tina Schröder et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Bis(2-aminoimidazoline) and Bisguanidine DNA Minor Groove Binders with Potent in Vivo Antitrypanosomal and Antiplasmodial Activity

(2008) Fernando Rodríguez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid   Protein Production

(2008) H. Shimizu et al.   MOLECULAR AND CELLULAR BIOLOGY

Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase

(2008) J. Zhong et al.   MOLECULAR CANCER THERAPEUTICS

The chemistry and biology of organic guanidine derivatives

(2008) Roberto G. S. Berlinck et al.   NATURAL PRODUCT REPORTS

Modified guanidine polymers: Synthesis and antimicrobial mechanism revealed by AFM

(2008) Liying Qian et al.   POLYMER

Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the substrate binding pocket

(2007) Lee D. Jennings et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Complexation of single strand telomere and telomerase RNA template polyanions by deoxyribonucleic guanidine (DNG) polycations: Plausible anticancer agents

(2007) Xiaohua Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Optimising brain penetration

(2007) Jens-Uwe Peters et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS