Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
出版年份 2020 全文链接
标题
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-12-18
DOI
10.1038/s41467-020-20225-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
- (2020) Jasper Wouters et al. NATURE CELL BIOLOGY
- Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation
- (2019) Mutsuko Minata et al. Cell Reports
- The landscape of the mesenchymal signature in brain tumours
- (2019) Jinan Behnan et al. BRAIN
- Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
- (2019) Stephen C. Mack et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
- (2019) Jan‐Philipp Mallm et al. Molecular Systems Biology
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
- (2019) Cyril Neftel et al. CELL
- Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling
- (2019) Ryan C Gimple et al. Cancer Discovery
- The phenotypes of proliferating glioblastoma cells reside on a single axis of variation
- (2019) Lin Wang et al. Cancer Discovery
- An advanced glioma cell invasion assay based on organotypic brain slice cultures
- (2018) Tanja Eisemann et al. BMC CANCER
- EnrichedHeatmap: an R/Bioconductor package for comprehensive visualization of genomic signal associations
- (2018) Zuguang Gu et al. BMC GENOMICS
- Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells
- (2018) Amelia Weber Hall et al. CANCER RESEARCH
- DNA methylation-based classification of central nervous system tumours
- (2018) David Capper et al. NATURE
- A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors
- (2018) Mariano J. Alvarez et al. NATURE GENETICS
- A glial blueprint for gliomagenesis
- (2018) Dylan Laug et al. NATURE REVIEWS NEUROSCIENCE
- Brain Cell Type Specific Gene Expression and Co-expression Network Architectures
- (2018) Andrew T. McKenzie et al. Scientific Reports
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
- (2018) Johanna Klughammer et al. NATURE MEDICINE
- Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme
- (2018) Tinyi Chu et al. NATURE GENETICS
- European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas
- (2017) Michael Weller et al. LANCET ONCOLOGY
- Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
- (2017) Sydney M. Shaffer et al. NATURE
- Reversed graph embedding resolves complex single-cell trajectories
- (2017) Xiaojie Qiu et al. NATURE METHODS
- Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis
- (2017) Stacey M Glasgow et al. NATURE NEUROSCIENCE
- BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation
- (2017) Himangi G. Marathe et al. NUCLEIC ACIDS RESEARCH
- Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
- (2017) Spyros Darmanis et al. Cell Reports
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Complex heatmaps reveal patterns and correlations in multidimensional genomic data
- (2016) Zuguang Gu et al. BIOINFORMATICS
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Models of human core transcriptional regulatory circuitries
- (2016) Violaine Saint-André et al. GENOME RESEARCH
- Functional characterization of somatic mutations in cancer using network-based inference of protein activity
- (2016) Mariano J Alvarez et al. NATURE GENETICS
- Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination
- (2016) Danyang He et al. NATURE NEUROSCIENCE
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
- (2016) Anna Segerman et al. Cell Reports
- STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
- (2015) J. Lau et al. CANCER RESEARCH
- Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes
- (2015) Temesgen D. Fufa et al. HUMAN MOLECULAR GENETICS
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells
- (2015) Patrick Laurette et al. eLife
- circlize implements and enhances circular visualization in R
- (2014) Zuguang Gu et al. BIOINFORMATICS
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
- (2014) Volker Hovestadt et al. NATURE
- Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
- (2014) Chong Sun et al. NATURE
- Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes
- (2014) Stacey M Glasgow et al. NATURE NEUROSCIENCE
- In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift
- (2014) J. Halliday et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation
- (2014) Artem D. Berezovsky et al. NEOPLASIA
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- Gene expression signature-based prognostic risk score in patients with glioblastoma
- (2013) Atsushi Kawaguchi et al. CANCER SCIENCE
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
- (2013) Wei Xie et al. CELL
- Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition
- (2013) Y. Piao et al. CLINICAL CANCER RESEARCH
- SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction
- (2013) Meng-Tsen Ke et al. NATURE NEUROSCIENCE
- Identification of active regulatory regions from DNA methylation data
- (2013) Lukas Burger et al. NUCLEIC ACIDS RESEARCH
- Master regulators of FGFR2 signalling and breast cancer risk
- (2013) Michael N. C. Fletcher et al. Nature Communications
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- (2012) S. G. Landt et al. GENOME RESEARCH
- Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
- (2012) Olga Shakhova et al. NATURE CELL BIOLOGY
- Sequentially acting Sox transcription factors in neural lineage development
- (2011) M. Bergsland et al. GENES & DEVELOPMENT
- DNA-binding factors shape the mouse methylome at distal regulatory regions
- (2011) Michael B. Stadler et al. NATURE
- The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence
- (2011) Wanyu L. Lambiv et al. NEURO-ONCOLOGY
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Molecular signatures classify astrocytic gliomas byIDH1mutation status
- (2010) Grischa Toedt et al. INTERNATIONAL JOURNAL OF CANCER
- Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas
- (2009) Christian Hartmann et al. ACTA NEUROPATHOLOGICA
- A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
- (2009) Chongzhi Zang et al. BIOINFORMATICS
- Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
- (2009) L. A.M. Gravendeel et al. CANCER RESEARCH
- Prognostic Significance of Molecular Markers and Extent of Resection in Primary Glioblastoma Patients
- (2009) J. Felsberg et al. CLINICAL CANCER RESEARCH
- Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research
- (2009) S. Madhavan et al. MOLECULAR CANCER RESEARCH
- The transcriptional network for mesenchymal transformation of brain tumours
- (2009) Maria Stella Carro et al. NATURE
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started