Master regulators of FGFR2 signalling and breast cancer risk

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

(2013) Juliet D. French et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

(2013) Qiyuan Li et al.   CELL

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

(2013) Montserrat Garcia-Closas et al.   NATURE GENETICS

FGFR2 Promotes Breast Tumorigenicity through Maintenance of Breast Tumor-Initiating Cells

(2013) Sungeun Kim et al.   PLoS One

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

(2012) V. Theodorou et al.   GENOME RESEARCH

The Transcription Factor SPDEF Suppresses Prostate Tumor Metastasis

(2012) Joshua J. Steffan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

(2012) Richard Cowper-Sal·lari et al.   NATURE GENETICS

RedeR: R/Bioconductor package for representing modular structures, nested networks and multiple levels of hierarchical associations.

(2012) Mauro AA Castro et al.   GENOME BIOLOGY

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes

(2011) Muhammad Riaz et al.   BREAST CANCER RESEARCH AND TREATMENT

Prostate derived ETS factor (PDEF): A putative tumor metastasis suppressor

(2011) Joshua J. Steffan et al.   CANCER LETTERS

Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

(2011) Yun-Yong Park et al.   EMBO Molecular Medicine

ETV6mutations in early immature human T cell leukemias

(2011) Pieter Van Vlierberghe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cellular reprogramming by the conjoint action of ER , FOXA1, and GATA3 to a ligand-inducible growth state

(2011) S. L. Kong et al.   Molecular Systems Biology

Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome

(2011) David Venet et al.   PLoS Computational Biology

FOXA1 is an essential determinant of ER  expression and mammary ductal morphogenesis

(2010) G. M. Bernardo et al.   DEVELOPMENT

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

(2010) Celine Lefebvre et al.   Molecular Systems Biology

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation

(2009) Miriam S. Udler et al.   HUMAN MOLECULAR GENETICS

ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions

(2009) Dominic Schmidt et al.   METHODS

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

minet: A R/Bioconductor Package for Inferring Large Transcriptional Networks Using Mutual Information

(2008) Patrick E Meyer et al.   BMC BIOINFORMATICS

GATA-3 and the regulation of the mammary luminal cell fate

(2008) Hosein Kouros-Mehr et al.   CURRENT OPINION IN CELL BIOLOGY

Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis

(2008) Pengfei Lu et al.   DEVELOPMENTAL BIOLOGY

Regulatory networks define phenotypic classes of human stem cell lines

(2008) Franz-Josef Müller et al.   NATURE

Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer

(2008) Kerstin B Meyer et al.   PLOS BIOLOGY

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

(2008) Montserrat Garcia-Closas et al.   PLoS Genetics

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY