A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

(2018) Presha Rajbhandari et al.   Cancer Discovery

An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

(2017) Logan A. Walsh et al.   Cell Reports

Molecular profiling of neuroendocrine malignancies to identify prognostic and therapeutic markers: a Fox Chase Cancer Center Pilot Study

(2016) Namrata Vijayvergia et al.   BRITISH JOURNAL OF CANCER

Functional characterization of somatic mutations in cancer using network-based inference of protein activity

(2016) Mariano J Alvarez et al.   NATURE GENETICS

Limits to Personalized Cancer Medicine

(2016) Ian F. Tannock et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management

(2016) Kjell Oberg et al.   Endocrine Connections

Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression

(2015) B. Bisikirska et al.   CANCER RESEARCH

Inhibition of the autocrine IL-6–JAK2–STAT3–calprotectin axis as targeted therapy for HR−/HER2+breast cancers

(2015) Ruth Rodriguez-Barrueco et al.   GENES & DEVELOPMENT

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models

(2015) Antonina Mitrofanova et al.   Cell Reports

Impact of centralization on aCGH-based genomic profiles for precision medicine in oncology

(2014) F. Commo et al.   ANNALS OF ONCOLOGY

Cross-Species Regulatory Network Analysis Identifies a Synergistic Interaction between FOXM1 and CENPF that Drives Prostate Cancer Malignancy

(2014) Alvaro Aytes et al.   CANCER CELL

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

Prospective Enterprise-Level Molecular Genotyping of a Cohort of Cancer Patients

(2014) Laura E. MacConaill et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia

(2013) Erich Piovan et al.   CANCER CELL

An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

(2013) Amrita Basu et al.   CELL

Which drug, and when, for patients with BRAF-mutant melanoma?

(2013) Sekwon Jang et al.   LANCET ONCOLOGY

Somatic mutation of CDKN1B in small intestine neuroendocrine tumors

(2013) Joshua M Francis et al.   NATURE GENETICS

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

The origin of neuroendocrine tumors and the neural crest saga

(2011) Juan Rosai   MODERN PATHOLOGY

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

(2011) Kariem Ezzat et al.   NUCLEIC ACIDS RESEARCH

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

(2010) Celine Lefebvre et al.   Molecular Systems Biology

Towards patient-based cancer therapeutics

(2010) Stuart L Schreiber et al.   NATURE BIOTECHNOLOGY

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

(2009) K. Basso et al.   BLOOD

Progression and treatment of HER2-positive breast cancer

(2009) April Davoli et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE