Lipodystrophy: A paradigm for understanding the consequences of "overloading" adipose tissue
出版年份 2020 全文链接
标题
Lipodystrophy: A paradigm for understanding the consequences of "overloading" adipose tissue
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume -, Issue -, Pages -
出版商
American Physiological Society
发表日期
2020-12-25
DOI
10.1152/physrev.00032.2020
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structure and mechanism of human diacylglycerol O-acyltransferase 1
- (2020) Lie Wang et al. NATURE
- Kawasaki disease shock syndrome: clinical characteristics and possible use of IL-6, IL-10 and IFN-γ as biomarkers for early recognition
- (2019) Yandie Li et al. Pediatric Rheumatology
- Interplay of lamin A and lamin B LADs on the radial positioning of chromatin
- (2019) Frida Forsberg et al. Nucleus
- Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact
- (2019) Veijo T. Salo et al. DEVELOPMENTAL CELL
- Diagnostic challenge in PLIN1-associated Familial Partial Lipodystrophy
- (2019) Isabelle Jéru et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Comorbidities and Survival in Patients with Lipodystrophy: An International Chart Review Study
- (2019) Baris Akinci et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Usefulness of Gemcabene in Homozygous Familial Hypercholesterolemia (from COBALT-1)
- (2019) Daniel Gaudet et al. AMERICAN JOURNAL OF CARDIOLOGY
- 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
- (2019) François Mach et al. EUROPEAN HEART JOURNAL
- An overview of lipodystrophy and the role of the complement system
- (2019) F. Corvillo et al. MOLECULAR IMMUNOLOGY
- LDAF1 and Seipin Form a Lipid Droplet Assembly Complex
- (2019) Jeeyun Chung et al. DEVELOPMENTAL CELL
- Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
- (2019) Gordon I. Smith et al. JOURNAL OF CLINICAL INVESTIGATION
- GDF15 mediates the effects of metformin on body weight and energy balance
- (2019) Anthony P. Coll et al. NATURE
- New medications targeting triglyceride-rich lipoproteins: Can inhibition of ANGPTL3 or apoC-III reduce the residual cardiovascular risk?
- (2018) Vesa M. Olkkonen et al. ATHEROSCLEROSIS
- An Asymmetry in Monolayer Tension Regulates Lipid Droplet Budding Direction
- (2018) Aymeric Chorlay et al. BIOPHYSICAL JOURNAL
- Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling
- (2018) Rayanne B. Burl et al. Cell Metabolism
- PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress
- (2018) Afreen Haider et al. DEVELOPMENTAL CELL
- A Pharmacogenetic Approach to the Treatment of Patients WithPPARGMutations
- (2018) Maura Agostini et al. DIABETES
- PLIN1 haploinsufficiency is not associated with lipodystrophy
- (2018) Thomas W Laver et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Metreleptin-mediated improvements in insulin sensitivity are independent of food intake in humans with lipodystrophy
- (2018) Rebecca J. Brown et al. JOURNAL OF CLINICAL INVESTIGATION
- “We're stuck with what we've got”: The impact of lipodystrophy on body image
- (2018) Claire Adams et al. JOURNAL OF CLINICAL NURSING
- Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major
- (2018) Shanshan Hu et al. Frontiers in Immunology
- A subset of patients with acquired partial lipodystrophy developing severe metabolic abnormalities
- (2018) Basak Ozgen Saydam et al. ENDOCRINE RESEARCH
- MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissue
- (2018) Emilie Capel et al. Journal of Clinical Lipidology
- A stromal cell population that inhibits adipogenesis in mammalian fat depots
- (2018) Petra C. Schwalie et al. NATURE
- Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility
- (2018) Sam Virtue et al. Cell Reports
- Polycystic ovary syndrome in Familial Partial Lipodystrophy Type 2 (FPLD2): basic and clinical aspects
- (2018) Alessandra Gambineri et al. Nucleus
- Starvation in the Midst of Plenty: Reflections on the History and Biology of Insulin and Leptin
- (2018) Jeffrey S Flier ENDOCRINE REVIEWS
- Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability
- (2018) Rosemary B. Cornell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regional Body Fat Changes and Metabolic Complications in Children with Dunnigan Lipodystrophy-causing LMNA Variants
- (2018) Nivedita Patni et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models
- (2018) Ashfaq Ahmad et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk
- (2017) S K Vasan et al. INTERNATIONAL JOURNAL OF OBESITY
- AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome
- (2017) Michael W O’Reilly et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Exome sequencing reveals a de novo POLD1 mutation causing phenotypic variability in mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome (MDPL)
- (2017) Sahar Elouej et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Structural insights into adiponectin receptors suggest ceramidase activity
- (2017) Ieva Vasiliauskaité-Brooks et al. NATURE
- Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
- (2017) Max C. Petersen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- A Novel Mutation in ERCC8 Gene Causing Cockayne Syndrome
- (2017) Maryam Taghdiri et al. Frontiers in Pediatrics
- Relationship between Regional Body Fat Distribution and Diabetes Mellitus: 2008 to 2010 Korean National Health and Nutrition Examination Surveys
- (2017) Soo In Choi et al. Diabetes & Metabolism Journal
- Determining residual adipose tissue characteristics with MRI in patients with various subtypes of lipodystrophy
- (2017) Canan Altay et al. Diagnostic and Interventional Radiology
- HomozygousLIPEmutation in siblings with multiple symmetric lipomatosis, partial lipodystrophy, and myopathy
- (2016) Sagit Zolotov et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- ‘Thank You, Doctor’ Says It All
- (2016) Joseph S. Alpert AMERICAN JOURNAL OF MEDICINE
- The Perilipins: Major Cytosolic Lipid Droplet–Associated Proteins and Their Roles in Cellular Lipid Storage, Mobilization, and Systemic Homeostasis
- (2016) Alan R. Kimmel et al. Annual Review of Nutrition
- Mandibuloacral dysplasia and LMNA A529V mutation in Turkish patients with severe skeletal changes and absent breast development
- (2016) Leyla Ozer et al. CLINICAL DYSMORPHOLOGY
- Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes
- (2016) Andres Digenio et al. DIABETES CARE
- Undiagnosed severe sleep apnoea and diabetic foot ulceration - a case series based hypothesis: a hitherto under emphasized factor in failure to heal
- (2016) P. R. J. Vas et al. DIABETIC MEDICINE
- Spectrum of clinical manifestations in two young Turkish patients with congenital generalized lipodystrophy type 4
- (2016) Gulcin Akinci et al. European Journal of Medical Genetics
- POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies
- (2016) Emmanuelle Nicolas et al. GENE
- Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3
- (2016) Emily R. Rowe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline
- (2016) Rebecca J. Brown et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Natural History of Congenital Generalized Lipodystrophy: A Nationwide Study From Turkey
- (2016) Baris Akinci et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- PI3-kinase mutation linked to insulin and growth factor resistance in vivo
- (2016) Jonathon N. Winnay et al. JOURNAL OF CLINICAL INVESTIGATION
- The long road to leptin
- (2016) Jeffrey Friedman JOURNAL OF CLINICAL INVESTIGATION
- Localized involutional lipoatrophy at the site of an influenza vaccination: A case report
- (2016) Yukiko Ninomiya et al. JOURNAL OF DERMATOLOGY
- Successful Treatment of an Unusual Case of FPLD2: The Role of Roux-en-Y Gastric Bypass—Case Report and Literature Review
- (2016) Sharon Grundfest-Broniatowski et al. JOURNAL OF GASTROINTESTINAL SURGERY
- A therapeutic cancer vaccine against GL261 murine glioma
- (2016) Mark S. Kindy et al. Journal of Translational Medicine
- Prospective functional classification of all possible missense variants in PPARG
- (2016) Amit R Majithia et al. NATURE GENETICS
- Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy
- (2016) Bing Han et al. TRAFFIC
- Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets
- (2016) Nora Kory et al. TRENDS IN CELL BIOLOGY
- Adiponectin, the past two decades
- (2016) Zhao V. Wang et al. Journal of Molecular Cell Biology
- Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study
- (2016) Glauce Cordeiro Ulhôa Tostes et al. Diabetology & Metabolic Syndrome
- SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase
- (2016) Martin Pagac et al. Cell Reports
- Depot-specific differences in angiogenic capacity of adipose tissue in differential susceptibility to diet-induced obesity
- (2016) Mun-Gyu Song et al. Molecular Metabolism
- AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue
- (2016) Kelly M. Cautivo et al. Molecular Metabolism
- Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
- (2016) Valentina Cappello et al. Scientific Reports
- Keppen-Lubinsky Syndrome Is Caused by Mutations in the Inwardly Rectifying K+ Channel Encoded by KCNJ6
- (2015) Andrea Masotti et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells
- (2015) Jop Kind et al. CELL
- LRP5 Regulates Human Body Fat Distribution by Modulating Adipose Progenitor Biology in a Dose- and Depot-Specific Fashion
- (2015) Nellie Y. Loh et al. Cell Metabolism
- Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes
- (2015) Juan R. Acosta et al. DIABETOLOGIA
- Adipose tissue morphology predicts improved insulin sensitivity following moderate or pronounced weight loss
- (2015) D Eriksson-Hogling et al. INTERNATIONAL JOURNAL OF OBESITY
- A conserved family of proteins facilitates nascent lipid droplet budding from the ER
- (2015) Vineet Choudhary et al. JOURNAL OF CELL BIOLOGY
- A Report of Three Cases With Acquired Generalized Lipodystrophy With Distinct Autoimmune Conditions Treated With Metreleptin
- (2015) Jasmin Lebastchi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production
- (2015) Anja Brehm et al. JOURNAL OF CLINICAL INVESTIGATION
- Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals
- (2015) Hongyi Zhou et al. JOURNAL OF LIPID RESEARCH
- From leptin to other adipokines in health and disease: Facts and expectations at the beginning of the 21st century
- (2015) Matthias Blüher et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin
- (2015) Lisa M. DiPilato et al. MOLECULAR AND CELLULAR BIOLOGY
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis
- (2015) Rosemary B. Cornell et al. PROGRESS IN LIPID RESEARCH
- Apolipoprotein C-III: From Pathophysiology to Pharmacology
- (2015) Giuseppe Danilo Norata et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Intergenerational and intrafamilial phenotypic variability in 22q11.2 Deletion syndrome subjects
- (2014) Emilia Cirillo et al. BMC Medical Genetics
- The pot calling the kettle black: the extent and type of errors in a computerized immunization registry and by parent report
- (2014) Shannon E MacDonald et al. BMC Pediatrics
- Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes
- (2014) Raymond E. Soccio et al. Cell Metabolism
- Loss of White Adipose Hyperplastic Potential Is Associated with Enhanced Susceptibility to Insulin Resistance
- (2014) Soo M. Kim et al. Cell Metabolism
- Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity
- (2014) R. A. Scott et al. DIABETES
- Adipose-Specific Knockout of Seipin/Bscl2 Results in Progressive Lipodystrophy
- (2014) L. Liu et al. DIABETES
- Neonatal progeroid variant of Marfan syndrome with congenital lipodystrophy results from mutations at the 3′ end of FBN1 gene
- (2014) Adeline Jacquinet et al. European Journal of Medical Genetics
- Metformin Improves Glucose Effectiveness, Not Insulin Sensitivity: Predicting Treatment Response in Women With Polycystic Ovary Syndrome in an Open-Label, Interventional Study
- (2014) Cindy T. Pau et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- 20 YEARS OF LEPTIN: Human disorders of leptin action
- (2014) I Sadaf Farooqi et al. JOURNAL OF ENDOCRINOLOGY
- CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization
- (2014) Anita Sahu-Osen et al. JOURNAL OF LIPID RESEARCH
- Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes
- (2014) Jessica S. Albert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Farmers’ market use is associated with fruit and vegetable consumption in diverse southern rural communities
- (2014) Stephanie B Jilcott Pitts et al. Nutrition Journal
- Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease
- (2014) F. Payne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thiazolidinediones and cancer: results of a meta-analysis of randomized clinical trials
- (2013) Matteo Monami et al. ACTA DIABETOLOGICA
- Severe congenital lipodystrophy and a progeroid appearance: Mutation in the penultimate exon ofFBN1causing a recognizable phenotype
- (2013) Toshiki Takenouchi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets
- (2013) Florian Wilfling et al. DEVELOPMENTAL CELL
- Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes
- (2013) H. Yaghootkar et al. DIABETES
- Type 2 Diabetes With Partial Lipodystrophy of the Limbs: A new lipodystrophy phenotype
- (2013) L. R. Strickland et al. DIABETES CARE
- Structural and Functional Properties of Deep Abdominal Subcutaneous Adipose Tissue Explain Its Association With Insulin Resistance and Cardiovascular Risk in Men
- (2013) Kyriakoula Marinou et al. DIABETES CARE
- Mfn2 modulates the UPR and mitochondrial function via repression of PERK
- (2013) Juan Pablo Muñoz et al. EMBO JOURNAL
- Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A p.R482W mutation elicits a myogenic gene expression program in preadipocytes
- (2013) Anja R. Oldenburg et al. HUMAN MOLECULAR GENETICS
- Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
- (2013) Richard S. Legro et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis
- (2013) Antonio Giordano et al. JOURNAL OF LIPID RESEARCH
- Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects
- (2013) Mikael Rydén et al. JOURNAL OF LIPID RESEARCH
- An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy
- (2013) Michael N Weedon et al. NATURE GENETICS
- Tracking adipogenesis during white adipose tissue development, expansion and regeneration
- (2013) Qiong A Wang et al. NATURE MEDICINE
- Venous Tumor Thrombus in Nonfunctional Pancreatic Neuroendocrine Tumors
- (2012) Aparna Balachandran et al. AMERICAN JOURNAL OF ROENTGENOLOGY
- Adiponectin and leptin in human severe insulin resistance – Diagnostic utility and biological insights
- (2012) M.P. Groeneveld et al. BIOCHIMIE
- Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo
- (2012) K. N. Manolopoulos et al. DIABETOLOGIA
- Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering drugs
- (2012) H. M. Colhoun et al. DIABETOLOGIA
- The adipose organ at a glance
- (2012) S. Cinti Disease Models & Mechanisms
- DNA polymerase delta in dna replication and genome maintenance
- (2012) Marc J. Prindle et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Phenotypic diversity in patients with lipodystrophy associated with LMNA mutations
- (2012) Patricia B Mory et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- A novel homozygous p.Arg527Leu LMNA mutation in two unrelated Egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome
- (2012) Mohammad Al-Haggar et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides andde novosynthesized fatty acids in HepG2 cells
- (2012) Haja R. Wurie et al. FEBS Journal
- Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity
- (2012) Jemima Barrowman et al. HUMAN MOLECULAR GENETICS
- Seipin: from human disease to molecular mechanism
- (2012) Bethany R. Cartwright et al. JOURNAL OF LIPID RESEARCH
- Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
- (2012) Timo D. Müller et al. JOURNAL OF PEPTIDE SCIENCE
- Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes
- (2012) Philip R. Schauer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes
- (2012) Geltrude Mingrone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome
- (2011) Xose S. Puente et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Progeroid facial features and lipodystrophy associated with a novel splice site mutation in the final intron of the FBN1 gene
- (2011) Denise Horn et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Thiazolidinediones Regulate Adipose Lineage Dynamics
- (2011) Wei Tang et al. Cell Metabolism
- Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase
- (2011) Natalie Krahmer et al. Cell Metabolism
- Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity
- (2011) Olga Gealekman et al. CIRCULATION
- Successful treatment for the Dunnigan-type familial partial lipodystrophy with Roux-en-Y gastric bypass
- (2011) Andreea Ciudin et al. CLINICAL ENDOCRINOLOGY
- Characterisation of non-obese diabetic patients with marked insulin resistance identifies a novel familial partial lipodystrophy-associated PPARγ mutation (Y151C)
- (2011) M. E. Visser et al. DIABETOLOGIA
- Human 1-Acylglycerol-3-phosphateO-Acyltransferase Isoforms 1 and 2
- (2011) Anil K. Agarwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Frame Shift Mutations Affecting the Carboxyl Terminus of Perilipin Increase Lipolysis by Failing to Sequester the Adipose Triglyceride Lipase (ATGL) Coactivator AB-hydrolase-containing 5 (ABHD5)
- (2011) Sheetal Gandotra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites
- (2011) Jingyi Gong et al. JOURNAL OF CELL BIOLOGY
- Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae
- (2011) N. Jacquier et al. JOURNAL OF CELL SCIENCE
- Insulin Resistance Is a Sufficient Basis for Hyperandrogenism in Lipodystrophic Women with Polycystic Ovarian Syndrome
- (2011) Andreea O. Lungu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans
- (2011) Akiko Kitamura et al. JOURNAL OF CLINICAL INVESTIGATION
- DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes
- (2011) Charles A. Harris et al. JOURNAL OF LIPID RESEARCH
- Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity
- (2011) Tova Meshulam et al. JOURNAL OF LIPID RESEARCH
- Surgical management of phenotypic alterations related to the Dunnigan variety of familial partial Lipodystrophy
- (2011) Davi Reis Calderoni et al. Journal of Plastic Reconstructive and Aesthetic Surgery
- Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes
- (2011) Daili J A Netz et al. Nature Chemical Biology
- Combined Gene and Protein Expression of Hormone-Sensitive Lipase and Adipose Triglyceride Lipase, Mitochondrial Content, and Adipocyte Size in Subcutaneous and Visceral Adipose Tissue of Morbidly Obese Men
- (2011) Hélène De Naeyer et al. Obesity Facts
- Layers of the abdominal wall: anatomical investigation of subcutaneous tissue and superficial fascia
- (2011) Luca Lancerotto et al. SURGICAL AND RADIOLOGIC ANATOMY
- The lamin protein family
- (2011) Travis A Dittmer et al. GENOME BIOLOGY
- PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome
- (2010) Anil K. Agarwal et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Comparative Epigenomic Analysis of Murine and Human Adipogenesis
- (2010) Tarjei S. Mikkelsen et al. CELL
- miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells
- (2010) M Tomé et al. CELL DEATH AND DIFFERENTIATION
- An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81
- (2010) Kashan Ahmed et al. Cell Metabolism
- Recent insights into fatty liver, metabolic dyslipidaemia and their links to insulin resistance
- (2010) David B Savage et al. CURRENT OPINION IN LIPIDOLOGY
- Resistance to leptin-replacement therapy in Berardinelli–Seip congenital lipodystrophy: an immunological origin
- (2010) Jacques Beltrand et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Caveolae at a glance
- (2010) M. Bastiani et al. JOURNAL OF CELL SCIENCE
- A Novel Syndrome of Mandibular Hypoplasia, Deafness, and Progeroid Features Associated with Lipodystrophy, Undescended Testes, and Male Hypogonadism
- (2010) Savitha Shastry et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Impact of Abdominal Visceral and Subcutaneous Adipose Tissue on Cardiometabolic Risk Factors: The Jackson Heart Study
- (2010) Jiankang Liu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Lipodystrophy: metabolic insights from a rare disorder
- (2010) Isabel Huang-Doran et al. JOURNAL OF ENDOCRINOLOGY
- Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria
- (2010) Sneha S. Prasad et al. JOURNAL OF LIPID RESEARCH
- Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway
- (2010) S. M. Choi et al. MOLECULAR AND CELLULAR BIOLOGY
- A Japanese child with asymptomatic elevation of serum creatine kinase shows PTRF-CAVIN mutation matching with congenital generalized lipodystrophy type 4
- (2010) Ery Kus Dwianingsih et al. MOLECULAR GENETICS AND METABOLISM
- Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1
- (2010) Masato Iwabu et al. NATURE
- Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
- (2010) William L Holland et al. NATURE MEDICINE
- Quantification of human body fat tissue percentage by MRI
- (2010) Hans-Peter Müller et al. NMR IN BIOMEDICINE
- Acquired Partial Lipodystrophy with C3 Hypocomplementemia and Antiphospholipid and Anticardiolipin Antibodies
- (2010) Sevgi Yavuz et al. PEDIATRIC DERMATOLOGY
- Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA
- (2009) Kun Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The Posttranslational Processing of Prelamin A and Disease
- (2009) Brandon S.J. Davies et al. Annual Review of Genomics and Human Genetics
- Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy
- (2009) Víctor A. Cortés et al. Cell Metabolism
- Point Mutations Are Causing Progeroid Phenotypes in the mtDNA Mutator Mouse
- (2009) Daniel Edgar et al. Cell Metabolism
- Efficacy of leptin therapy in the different forms of human lipodystrophy
- (2009) A. Y. Chong et al. DIABETOLOGIA
- Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC
- (2009) Oscar Rubio-Cabezas et al. EMBO Molecular Medicine
- Lipoatrophy associated with the use of insulin analogues: a new case associated with the use of insulin glargine and review of the literature
- (2009) Andreas Holstein et al. Expert Opinion On Drug Safety
- Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL
- (2009) Kristoffer Ström et al. FASEB JOURNAL
- Atypical Progeroid Syndrome due to Heterozygous MissenseLMNAMutations
- (2009) Abhimanyu Garg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy
- (2009) Yukiko K. Hayashi et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of probiotic bacteria, isoflavones and simvastatin on lipid profile and atherosclerosis in cholesterol-fed rabbits: a randomized double-blind study
- (2009) Daniela CU Cavallini et al. Lipids in Health and Disease
- Clinical characteristics and efficacy of pioglitazone in a Japanese diabetic patient with an unusual type of familial partial lipodystrophy
- (2009) Masanori Iwanishi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Predicting abdominal adipose tissue among women with familial partial lipodystrophy
- (2009) Tisha Joy et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ
- (2009) Michael K Swan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Injection-Site Lipoatrophy
- (2009) Adziri Harold Sackey NEW ENGLAND JOURNAL OF MEDICINE
- Pioglitazone Increases the Proportion of Small Cells in Human Abdominal Subcutaneous Adipose Tissue
- (2009) Tracey M. McLaughlin et al. Obesity
- De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis
- (2009) Mohamed Sabry Hamza et al. PLoS One
- Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes
- (2009) Arnold Hayer et al. TRAFFIC
- Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome
- (2009) Yun Jeong Doh et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function
- (2008) Michelle M. Hill et al. CELL
- Identification of White Adipocyte Progenitor Cells In Vivo
- (2008) Matthew S. Rodeheffer et al. CELL
- Deletion of Cavin/PTRF Causes Global Loss of Caveolae, Dyslipidemia, and Glucose Intolerance
- (2008) Libin Liu et al. Cell Metabolism
- Lipodystrophy Syndromes
- (2008) Pedro Herranz et al. DERMATOLOGIC CLINICS
- Relationship of Abdominal Visceral and Subcutaneous Adipose Tissue With Lipoprotein Particle Number and Size in Type 2 Diabetes
- (2008) S. Sam et al. DIABETES
- Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX™
- (2008) Rachel M Williams et al. Expert Opinion on Drug Metabolism & Toxicology
- Genome-wide profiling of PPAR :RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
- (2008) R. Nielsen et al. GENES & DEVELOPMENT
- PPAR and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale
- (2008) M. I. Lefterova et al. GENES & DEVELOPMENT
- HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options
- (2008) J. E. Mallewa et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Fat-specific Protein 27 Regulates Storage of Triacylglycerol
- (2008) Pernille Keller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Severe Mandibuloacral Dysplasia-Associated Lipodystrophy and Progeria in a Young Girl with a Novel Homozygous Arg527CysLMNAMutation
- (2008) Anil K. Agarwal et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fertility and Obstetrical Complications in Women withLMNA-Related Familial Partial Lipodystrophy
- (2008) M. C. Vantyghem et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy
- (2008) C. A. Kim et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fatty Acid Metabolism in Patients with PPARγ Mutations
- (2008) Garry D. Tan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Complement Abnormalities in Acquired Lipodystrophy Revisited
- (2008) David B. Savage et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Localized involutional lipoatrophy with epidermal and dermal changes
- (2008) Ossama Abbas et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Effects of flavonoids on sphingolipid turnover in the toxin-damaged liver and liver cells
- (2008) Nataliya A Babenko et al. Lipids in Health and Disease
- Dynamics of fat cell turnover in humans
- (2008) Kirsty L. Spalding et al. NATURE
- Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
- (2008) Lars Guelen et al. NATURE
- Transcriptional repression mediated by repositioning of genes to the nuclear lamina
- (2008) K. L. Reddy et al. NATURE
- Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells
- (2008) Coralie Fontaine et al. STEM CELLS
- Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets
- (2008) Lars Kuerschner et al. TRAFFIC
- Type 1 Diabetes Associated with Acquired Generalized Lipodystrophy and Insulin Resistance: The Effect of Long-Term Leptin Therapy
- (2007) Jean Y. Park et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started