In-silico prediction of potential inhibitors against phosphatidylinositol 3-kinase catalytic subunit alpha involved in head and neck squamous cell carcinomas

Salvage surgery in head and neck cancer: Does it improve outcomes?

(2020) Vijay Maruti Patil et al.   EJSO

Systemic Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma- A Systematic Review and Meta-Analysis

(2020) Ashley Lau et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Beyond EGFR Targeting in SCCHN: Angiogenesis, PI3K, and Other Molecular Targets

(2019) Esma Saada-Bouzid et al.   Frontiers in Oncology

PI3K/AKT/mTOR Signaling Regulates the Virus/Host Cell Crosstalk in HPV-Positive Cervical Cancer Cells

(2019) Felicitas Bossler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review

(2019) Barbora Peltanova et al.   Molecular Cancer

Clinical update on head and neck cancer: molecular biology and ongoing challenges

(2019) Elham Alsahafi et al.   Cell Death & Disease

Target identification, screening and in vivo evaluation of pyrrolone-fused benzosuberene compounds against human epilepsy using Zebrafish model of pentylenetetrazol-induced seizures

(2019) Garima Tanwar et al.   Scientific Reports

Structural Perturbations due to Mutation (H1047R) in Phosphoinositide-3-kinase (PI3Kα) and Its Involvement in Oncogenesis: An in Silico Insight

(2019) Jatin Sharma et al.   ACS Omega

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines

(2018) Nachi Namatame et al.   Oncotarget

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo

(2017) Chih-Chia Yu et al.   Oncotarget

Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

(2017) Wennan Zhao et al.   Acta Pharmaceutica Sinica B

PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment

(2016) Angel Guerrero-Zotano et al.   CANCER AND METASTASIS REVIEWS

Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives

(2016) Simonetta Ausoni et al.   CANCER AND METASTASIS REVIEWS

Aetiology and risk factors for head and neck cancer: United Kingdom National Multidisciplinary Guidelines

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Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Structural basis of nSH2 regulation and lipid binding in PI3Kα

(2015) Michelle S. Miller et al.   Oncotarget

Rapid decomposition and visualisation of protein–ligand binding free energies by residue and by water

(2014) Christopher J. Woods et al.   FARADAY DISCUSSIONS

g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations

(2014) Rashmi Kumari et al.   Journal of Chemical Information and Modeling

Investigating the Structure and Dynamics of the PIK3CA Wild-Type and H1047R Oncogenic Mutant

(2014) Paraskevi Gkeka et al.   PLoS Computational Biology

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(2014) Gurkan Yardimci   World Journal of Clinical Cases

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

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Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Exploiting the Head and Neck Cancer Oncogenome: Widespread PI3K-mTOR Pathway Alterations and Novel Molecular Targets

(2013) R. Iglesias-Bartolome et al.   Cancer Discovery

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY