Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review
出版年份 2019 全文链接
标题
Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review
作者
关键词
Tumor microenvironment, Head and neck cancer, Tumor metabolism, Epithelial-mesenchymal transition
出版物
Molecular Cancer
Volume 18, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-03-30
DOI
10.1186/s12943-019-0983-5
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- TGF-β1/TβRII/Smad3 signaling pathway promotes VEGF expression in oral squamous cell carcinoma tumor-associated macrophages
- (2018) Haibin Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression
- (2018) Dhruv Kumar et al. CANCER RESEARCH
- Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion
- (2018) Yu Ren et al. Molecular Cancer
- High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
- (2018) Imelda Seminerio et al. Oncotarget
- NEDD9 stimulated MMP9 secretion is required for invadopodia formation in oral squamous cell carcinoma
- (2018) Stéphane Grauzam et al. Oncotarget
- TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma
- (2018) Kazumasa Moriwaki et al. Oncotarget
- Caspase-1 from Human Myeloid-Derived Suppressor Cells Can Promote T Cell–Independent Tumor Proliferation
- (2018) Qi Zeng et al. Cancer Immunology Research
- CD8+ and CD163+ infiltrating cells and PD-L1 immunoexpression in oral leukoplakia and oral carcinoma
- (2018) Olga Stasikowska-Kanicka et al. APMIS
- Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets
- (2018) Saúl Álvarez-Teijeiro et al. Cancers
- Vimentin and Non-Muscle Myosin IIA are Members of the Neural Precursor Cell Expressed Developmentally Down-Regulated 9 (NEDD9) Interactome in Head and Neck Squamous Cell Carcinoma Cells
- (2018) Martina Semelakova et al. Translational Oncology
- Continuing rise in oropharyngeal cancer in a high HPV prevalence area: A Danish population-based study from 2011 to 2014
- (2017) Amanda-Louise Fenger Carlander et al. EUROPEAN JOURNAL OF CANCER
- Oral squamous cell carcinoma suppressed antitumor immunity through induction of PD-L1 expression on tumor-associated macrophages
- (2017) Canhua Jiang et al. IMMUNOBIOLOGY
- Recruited monocytic myeloid-derived suppressor cells promote the arrest of tumor cells in the premetastatic niche through an IL-1β-mediated increase in E-selectin expression
- (2017) Huifang Shi et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin
- (2017) Begum Erdogan et al. JOURNAL OF CELL BIOLOGY
- Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma
- (2017) Liang Mao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma
- (2017) Hui-Min Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
- (2017) Yu-Chan Chang et al. Journal of Hematology & Oncology
- Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1α-MTDH loop
- (2017) Gangcai Zhu et al. ONCOLOGY REPORTS
- Prognostic markers in oropharyngeal squamous cell carcinoma: focus on CD70 and tumour infiltrating lymphocytes
- (2017) Astrid De Meulenaere et al. PATHOLOGY
- Immunohistochemical Analysis of Foxp3+, CD4+, CD8+ Cell Infiltrates and PD-L1 in Oral Squamous Cell Carcinoma
- (2017) Olga Stasikowska-Kanicka et al. PATHOLOGY & ONCOLOGY RESEARCH
- Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane
- (2017) Alexandros Glentis et al. Nature Communications
- Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
- (2017) Maria Ouzounova et al. Nature Communications
- Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 expression is not prognostic
- (2017) Kenneth Oguejiofor et al. Oncotarget
- Peripheral Blood Neutrophil Granulocytes from Patients with Head and Neck Squamous Cell Carcinoma Functionally Differ from Their Counterparts in Healthy Donors
- (2017) S. Trellakis et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Impact of human monocyte and macrophage polarization on NLR expression and NLRP3 inflammasome activation
- (2017) Fawaz Awad et al. PLoS One
- β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells
- (2017) Rafael Peláez et al. PLoS One
- CD163+CD204+ tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma
- (2017) Keigo Kubota et al. Scientific Reports
- A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity
- (2016) Benjamaporn Wonganu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Aged neutrophils contribute to the first line of defense in the acute inflammatory response
- (2016) B. Uhl et al. BLOOD
- Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma
- (2016) Jing-Jing Song et al. BMC CANCER
- Prognostic significance of monocarboxylate transporter expression in oral cavity tumors
- (2016) Susana Simões-Sousa et al. CELL CYCLE
- Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry
- (2016) Flavia S. Lakschevitz et al. EXPERIMENTAL CELL RESEARCH
- Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma
- (2016) Nghia Nguyen et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- CD56-positive lymphocyte infiltration in relation to human papillomavirus association and prognostic significance in oropharyngeal squamous cell carcinoma
- (2016) Steffen Wagner et al. INTERNATIONAL JOURNAL OF CANCER
- Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells
- (2016) Tao Shan et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Human Head and Neck Squamous Cell Carcinoma–Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells
- (2016) Rania H. Younis et al. JOURNAL OF IMMUNOLOGY
- Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI)
- (2016) I García-Palmero et al. ONCOGENE
- Prognostic significance of macrophage polarization in early stage oral squamous cell carcinomas
- (2016) Manuel Weber et al. ORAL ONCOLOGY
- Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream
- (2016) Martin R. Weber et al. THROMBOSIS RESEARCH
- Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures
- (2016) Elizabete Bagordakis et al. TUMOR BIOLOGY
- Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells
- (2016) A. Spiegel et al. Cancer Discovery
- The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma
- (2016) Shinji Iizuka et al. Oncotarget
- Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC
- (2016) Ali Khammanivong et al. Oncotarget
- Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling
- (2016) Eunice Yuen Ting Lau et al. Cell Reports
- Temporal phenotypic features distinguish polarized macrophagesin vitro
- (2015) David W. Melton et al. AUTOIMMUNITY
- Biomimetic LBL structured nanofibrous matrices assembled by chitosan/collagen for promoting wound healing
- (2015) Rong Huang et al. BIOMATERIALS
- Immunoexpression of tenascin as a predictor of the malignancy potential of oral leukoplakia associated with a tobacco habit
- (2015) DR Mane et al. BIOTECHNIC & HISTOCHEMISTRY
- Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment
- (2015) Kazumasa Mori et al. BMC CANCER
- The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis
- (2015) Caecilia Hapsari Ceriapuri Sukowati et al. BMC CANCER
- Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator
- (2015) Han Zhang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma
- (2015) Hideyuki Takahashi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
- (2015) I. Acerbi et al. Integrative Biology
- Type IIFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human
- (2015) Lisa Andzinski et al. INTERNATIONAL JOURNAL OF CANCER
- Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat
- (2015) Ashley C. Brown et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evaluation of stromal myofibroblasts in oral leukoplakia, oral submucous fibrosis, and oral squamous cell carcinoma - an immunohistochemical study
- (2015) Kanupriya Gupta et al. Journal of Cancer Research and Therapeutics
- Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity
- (2015) C. Cimen Bozkus et al. JOURNAL OF IMMUNOLOGY
- Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry
- (2015) Gavin M. Mason et al. JOURNAL OF IMMUNOLOGY
- Expression of cancer-associated fibroblast related proteins in metastatic breast cancer: an immunohistochemical analysis
- (2015) Hye Min Kim et al. Journal of Translational Medicine
- Quantification of Extracellular Matrix Proteins from a Rat Lung Scaffold to Provide a Molecular Readout for Tissue Engineering
- (2015) Ryan C. Hill et al. MOLECULAR & CELLULAR PROTEOMICS
- Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma
- (2015) Chieh-Wen Cheng et al. MOLECULAR CARCINOGENESIS
- Transient transfection of macrophage migration inhibitory factor small interfering RNA disrupts the biological behavior of oral squamous carcinoma cells
- (2015) JIE ZENG et al. Molecular Medicine Reports
- Microlocalization of CD68+ tumor-associated macrophages in tumor stroma correlated with poor clinical outcomes in oral squamous cell carcinoma patients
- (2015) Yan-Hong Ni et al. TUMOR BIOLOGY
- Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1
- (2015) Yi-Chen Yen et al. Oncotarget
- TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT
- (2015) Junlong Zhuang et al. Scientific Reports
- Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling
- (2015) Xu Zhou et al. Scientific Reports
- TNF Counterbalances the Emergence of M2 Tumor Macrophages
- (2015) Franz Kratochvill et al. Cell Reports
- The Regulatory Role of Invariant NKT Cells in Tumor Immunity
- (2015) Rosanna M. McEwen-Smith et al. Cancer Immunology Research
- Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway
- (2015) J. E. Glogauer et al. Cancer Immunology Research
- Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux
- (2015) Mélanie R. Tardif et al. Journal of Immunology Research
- Macrophages Modulate Migration and Invasion of Human Tongue Squamous Cell Carcinoma
- (2015) Emma Pirilä et al. PLoS One
- Fibroblast Growth Factor (FGF-2) and Its Receptors FGFR-2 and FGFR-3 May Be Putative Biomarkers of Malignant Transformation of Potentially Malignant Oral Lesions into Oral Squamous Cell Carcinoma
- (2015) Seema Nayak et al. PLoS One
- Beyond allergy: the role of mast cells in fibrosis
- (2015) T Hügle SWISS MEDICAL WEEKLY
- Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors
- (2015) Constantin Jotzu et al. Analytical Cellular Pathology
- Cross talk Initiated by Endothelial Cells Enhances Migration and Inhibits Anoikis of Squamous Cell Carcinoma Cells through STAT3/Akt/ERK Signaling
- (2015) Kathleen G. Neiva et al. NEOPLASIA
- Regulation of Membrane-Type 4 Matrix Metalloproteinase by SLUG Contributes to Hypoxia-Mediated Metastasis
- (2015) Chi-Hung Huang et al. NEOPLASIA
- Rac1 as a potential therapeutic target for chemo-radioresistant head and neck squamous cell carcinomas (HNSCC)
- (2014) S Skvortsov et al. BRITISH JOURNAL OF CANCER
- Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
- (2014) M. Augsten et al. CANCER RESEARCH
- Platelets promote osteosarcoma cell growth through activation of the platelet-derived growth factor receptor-Akt signaling axis
- (2014) Satoshi Takagi et al. CANCER SCIENCE
- Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment
- (2014) D. Herrmann et al. CARCINOGENESIS
- Tadalafil Reduces Myeloid-Derived Suppressor Cells and Regulatory T Cells and Promotes Tumor Immunity in Patients with Head and Neck Squamous Cell Carcinoma
- (2014) D. T. Weed et al. CLINICAL CANCER RESEARCH
- Immunohistochemical Correlation of Matrix Metalloproteinase-2 and Tissue Inhibitors of Metalloproteinase-2 in Tobacco Associated Epithelial Dysplasia
- (2014) Dipshikha Bajracharya et al. DISEASE MARKERS
- Inter-relation of Th1, Th2, Th17 and Treg cytokines in oral cancer patients and their clinical significance
- (2014) Poonam Gaur et al. HUMAN IMMUNOLOGY
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration
- (2014) Naoyuki Makita et al. INTERNATIONAL IMMUNOLOGY
- S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells
- (2014) Emmanuel J. Silva et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Small oral squamous cell carcinomas with nodal lymphogenic metastasis show increased infiltration of M2 polarized macrophages – An immunohistochemical analysis
- (2014) Manuel Weber et al. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CTLA4 Expression Is an Indicator and Regulator of Steady-State CD4+FoxP3+ T Cell Homeostasis
- (2014) A. L. Tang et al. JOURNAL OF IMMUNOLOGY
- Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells
- (2014) P. Sinha et al. JOURNAL OF IMMUNOLOGY
- Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
- (2014) J.-I. Youn et al. JOURNAL OF IMMUNOLOGY
- A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma
- (2014) Bin Zhou et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
- (2014) Ovijit Chaudhuri et al. NATURE MATERIALS
- Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression
- (2014) Janna K Mouw et al. NATURE MEDICINE
- Neutrophils Infiltration in the Tongue Squamous Cell Carcinoma and Its Correlation with CEACAM1 Expression on Tumor Cells
- (2014) Ning Wang et al. PLoS One
- Monocarboxylate Transporter 4 Facilitates Cell Proliferation and Migration and Is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma Patients
- (2014) Jiang Zhu et al. PLoS One
- Platelets guide the formation of early metastatic niches
- (2014) M. Labelle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TSPAN12 is a critical factor for cancer–fibroblast cell contact-mediated cancer invasion
- (2014) Ryo Otomo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KLRG+ invariant natural killer T cells are long-lived effectors
- (2014) K. Shimizu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF-beta in CAF-mediated tumor growth and metastasis
- (2014) A. Calon et al. SEMINARS IN CANCER BIOLOGY
- Stromal myofibroblasts in potentially malignant and malignant lesions of the oral cavity
- (2014) PRISCILA CAMPIONI RODRIGUES et al. Oncology Letters
- Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein
- (2014) Le-Xing Yu et al. Nature Communications
- Effect of the Premalignant and Tumor Microenvironment on Immune Cell Cytokine Production in Head and Neck Cancer
- (2014) Sara Johnson et al. Cancers
- Incidence of Mast Cells in Oral Squamous Cell Carcinoma: A Short Study
- (2014) A. Anuradha et al. Journal of Oncology
- VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice
- (2013) S. Ferjancic et al. BLOOD
- The FGFR1 inhibitor PD173074 induces mesenchymal–epithelial transition through the transcription factor AP-1
- (2013) P T Nguyen et al. BRITISH JOURNAL OF CANCER
- Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor
- (2013) Dagmar Schumacher et al. CANCER CELL
- Cetuximab Attenuates Its Cytotoxic and Radiosensitizing Potential by Inducing Fibronectin Biosynthesis
- (2013) I. Eke et al. CANCER RESEARCH
- Acidity Generated by the Tumor Microenvironment Drives Local Invasion
- (2013) V. Estrella et al. CANCER RESEARCH
- Integrin v 3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis
- (2013) L. M. Knowles et al. CANCER RESEARCH
- Connective Tissue Growth Factor Activates Pluripotency Genes and Mesenchymal–Epithelial Transition in Head and Neck Cancer Cells
- (2013) Cheng-Chi Chang et al. CANCER RESEARCH
- Cancer metabolism, stemness and tumor recurrence
- (2013) Joseph M. Curry et al. CELL CYCLE
- Molecular mechanisms of natural killer cell activation in response to cellular stress
- (2013) C J Chan et al. CELL DEATH AND DIFFERENTIATION
- Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models
- (2013) Sarah Elizabeth Wheeler et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Expression of type IV collagen in different histological grades of oral squamous cell carcinoma: An immunohistochemical study
- (2013) Pankaj Agarwal et al. Journal of Cancer Research and Therapeutics
- Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
- (2013) Begoña Díaz et al. JOURNAL OF CELL BIOLOGY
- Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells
- (2013) A. Jacob et al. JOURNAL OF CELL SCIENCE
- Impact of S100A8/A9 Expression on Prostate Cancer Progression In Vitro and In Vivo
- (2013) Sina Grebhardt et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
- (2013) Jonathan Cools-Lartigue et al. JOURNAL OF CLINICAL INVESTIGATION
- STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
- (2013) David Vasquez-Dunddel et al. JOURNAL OF CLINICAL INVESTIGATION
- Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A
- (2013) Fiorenza Lotti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis
- (2013) Pilar Sandoval et al. JOURNAL OF PATHOLOGY
- M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway
- (2013) Chao-Ying Liu et al. LABORATORY INVESTIGATION
- Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- YAP forces fibroblasts to feel the tension
- (2013) Ori Maller et al. NATURE CELL BIOLOGY
- SOX2 Targets Fibronectin 1 to Promote Cell Migration and Invasion in Ovarian Cancer: New Molecular Leads for Therapeutic Intervention
- (2013) Xiaoyan Lou et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Cancer-Associated Fibroblasts from Hepatocellular Carcinoma Promote Malignant Cell Proliferation by HGF Secretion
- (2013) Chang-Chang Jia et al. PLoS One
- FOXP3 Subcellular Localization Predicts Recurrence in Oral Squamous Cell Carcinoma
- (2013) Donald T. Weed et al. PLoS One
- S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1
- (2013) Jean-Christophe Simard et al. PLoS One
- Expression of M2-Polarized Macrophages is Associated with Poor Prognosis for Advanced Epithelial Ovarian Cancer
- (2013) Chunyan Lan et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- Notch signaling induces EMT in OSCC cell lines in a hypoxic environment
- (2013) TAKAYUKI ISHIDA et al. Oncology Letters
- Quality of life of patients with head and neck cancer
- (2013) Mário Rodrigues de Melo Filho et al. Brazilian Journal of Otorhinolaryngology
- Neutrophils Activate Tumoral CORTACTIN to Enhance Progression of Orohypopharynx Carcinoma
- (2013) Claudia A. Dumitru et al. Frontiers in Immunology
- Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice
- (2012) A. M. Gil-Bernabe et al. BLOOD
- Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
- (2012) Jaclyn Sceneay et al. CANCER RESEARCH
- Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression
- (2012) Young Sun Hwang et al. CARCINOGENESIS
- Laminin Interactions with Head and Neck Cancer Cells under Low Fluid Shear Conditions Lead to Integrin Activation and Binding
- (2012) Susan M. Fennewald et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Mast Cells Critically Augment Myeloid-Derived Suppressor Cell Activity
- (2012) S. J. Saleem et al. JOURNAL OF IMMUNOLOGY
- Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance
- (2012) Nobuyuki Fujii et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Macrophage plasticity and polarization in tissue repair and remodelling
- (2012) Alberto Mantovani et al. JOURNAL OF PATHOLOGY
- Loss of E-cadherin and Acquisition of Vimentin in Epithelial-Mesenchymal Transition are Noble Indicators of Uterine Cervix Cancer Progression
- (2012) Na-Hye Myong Korean Journal of Pathology
- Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion
- (2012) E.E. Hinsley et al. LIFE SCIENCES
- Cancer-Associated Fibroblasts Induce Matrix Metalloproteinase-Mediated Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cells
- (2012) A.-C. Johansson et al. MOLECULAR CANCER RESEARCH
- A helping hand from neutrophils in T cell–independent antibody responses?
- (2012) Stuart G Tangye et al. NATURE IMMUNOLOGY
- Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo
- (2012) Bryan G Yipp et al. NATURE MEDICINE
- Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells
- (2012) K E Luker et al. ONCOGENE
- Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop
- (2012) K E Hayes et al. ONCOGENE
- Tumor-associated macrophages and the profile of inflammatory cytokines in oral squamous cell carcinoma
- (2012) Nadia Lago Costa et al. ORAL ONCOLOGY
- Immunohistochemical study of p53, Ki-67, MMP-2 and MMP-9 expression at invasive front of squamous cell and verrucous carcinoma in oral cavity
- (2012) Nooshin Mohtasham et al. PATHOLOGY RESEARCH AND PRACTICE
- Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis
- (2012) M. Demers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs
- (2012) LIAN LIAN et al. Oncology Letters
- In Vivo Invasion of Head and Neck Squamous Cell Carcinoma Cells Does Not Require Macrophages
- (2011) Tatiana Smirnova et al. AMERICAN JOURNAL OF PATHOLOGY
- The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin
- (2011) Osvaldo Pontiggia et al. BREAST CANCER RESEARCH AND TREATMENT
- Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs
- (2011) Qing Chen et al. CANCER CELL
- Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
- (2011) Michael Quante et al. CANCER CELL
- Characterization of the evolution of immune phenotype during the development and progression of squamous cell carcinoma of the head and neck
- (2011) Anna-Maria A. De Costa et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells
- (2011) T. Placke et al. CANCER RESEARCH
- Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
- (2011) Jacky G. Goetz et al. CELL
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- Targeting Galectin-1 in Carcinoma-Associated Fibroblasts Inhibits Oral Squamous Cell Carcinoma Metastasis by Downregulating MCP-1/CCL2 Expression
- (2011) Ming-Heng Wu et al. CLINICAL CANCER RESEARCH
- Illumina whole-genome complementary DNA–mediated annealing, selection, extension and ligation platform: assessing its performance in formalin-fixed, paraffin-embedded samples and identifying invasion pattern–related genes in oral squamous cell carcinoma
- (2011) Olivier Loudig et al. HUMAN PATHOLOGY
- MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
- (2011) James Finke et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Tumor-derived macrophage migration inhibitory factor modulates the biology of head and neck cancer cells via neutrophil activation
- (2011) Claudia A. Dumitru et al. INTERNATIONAL JOURNAL OF CANCER
- The monocarboxylate transporter family-Structure and functional characterization
- (2011) Andrew P. Halestrap IUBMB LIFE
- A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1
- (2011) Janesh Pillay et al. JOURNAL OF CLINICAL INVESTIGATION
- Mast cells and histamine enhance the proliferation of non-small cell lung cancer cells
- (2011) Evgeniy Stoyanov et al. LUNG CANCER
- Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells
- (2011) Sittichai Koontongkaew et al. MEDICAL ONCOLOGY
- S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression
- (2011) M. Ichikawa et al. MOLECULAR CANCER RESEARCH
- Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment
- (2011) Jonathan W. Wojtkowiak et al. MOLECULAR PHARMACEUTICS
- Suppressor of cytokine signaling 1 interacts with oncogenic lymphocyte-specific protein tyrosine kinase
- (2011) Yu ONCOLOGY REPORTS
- Expression and prognostic impact of indoleamine 2,3-dioxygenase in oral squamous cell carcinomas
- (2011) Klaus Laimer et al. ORAL ONCOLOGY
- Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients
- (2011) Monique M. Nijkamp et al. RADIOTHERAPY AND ONCOLOGY
- Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor
- (2011) Benjamin Toh et al. PLOS BIOLOGY
- A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
- (2010) S Y Nam et al. BRITISH JOURNAL OF CANCER
- Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin 5 1 and Fibronectin
- (2010) J.-M. Nam et al. CANCER RESEARCH
- Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness
- (2010) E. Giannoni et al. CANCER RESEARCH
- Natural Killer Cell Education and Tolerance
- (2010) Mark T. Orr et al. CELL
- Cancer-associated fibroblasts and epithelial-mesenchymal transition in metastatic oral tongue squamous cell carcinoma
- (2010) Marilena Vered et al. INTERNATIONAL JOURNAL OF CANCER
- Polymorphonuclear granulocytes in human head and neck cancer: Enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease
- (2010) Sokratis Trellakis et al. INTERNATIONAL JOURNAL OF CANCER
- Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44
- (2010) Céline Pinheiro et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation
- (2010) L. C. Kelley et al. JOURNAL OF CELL SCIENCE
- Visualizing extravasation dynamics of metastatic tumor cells
- (2010) K. Stoletov et al. JOURNAL OF CELL SCIENCE
- Neutrophils responsive to endogenous IFN-β regulate tumor angiogenesis and growth in a mouse tumor model
- (2010) Jadwiga Jablonska et al. JOURNAL OF CLINICAL INVESTIGATION
- Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells
- (2010) M. G. Lechner et al. JOURNAL OF IMMUNOLOGY
- EGF/TGFβ1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332
- (2010) Petra Richter et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Stromal features are predictive of disease mortality in oral cancer patients
- (2010) Daniel Marsh et al. JOURNAL OF PATHOLOGY
- Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma
- (2010) Kue Peng Lim et al. JOURNAL OF PATHOLOGY
- Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab
- (2010) Gerald W. Prager et al. Molecular Oncology
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses
- (2010) Silke Paust et al. NATURE IMMUNOLOGY
- TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
- (2010) M E Kupferman et al. ONCOGENE
- Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent
- (2010) J T Lucas et al. ONCOGENE
- Hypoxia-inducible factor-1 alpha, in association with TWIST2 and SNIP1, is a critical prognostic factor in patients with tongue squamous cell carcinoma
- (2010) Xinhua Liang et al. ORAL ONCOLOGY
- Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer
- (2010) Ibrahim O. Bello et al. ORAL ONCOLOGY
- Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model
- (2010) Zhuoshun Yang et al. PLoS One
- Extracellular DNA traps promote thrombosis
- (2010) T. A. Fuchs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunohistochemical analysis of integrins αvβ3, αvβ5 and α5β1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human oral head and neck squamous cell carcinomas
- (2010) EVA-MARIA FABRICIUS et al. Experimental and Therapeutic Medicine
- Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines
- (2010) Shuyi Zhang et al. PLoS Neglected Tropical Diseases
- Matrix metalloproteinases: Fold and function of their catalytic domains
- (2009) Cynthia Tallant et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of human NK-cell cytokine and chemokine production by target cell recognition
- (2009) C. Fauriat et al. BLOOD
- Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
- (2009) Zvi G. Fridlender et al. CANCER CELL
- Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine
- (2009) M. K. Srivastava et al. CANCER RESEARCH
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer
- (2009) L. M. Knowles et al. CLINICAL CANCER RESEARCH
- Hypoxia and Radiation Therapy: Past History, Ongoing Research, and Future Promise
- (2009) Sara Rockwell et al. CURRENT MOLECULAR MEDICINE
- The extracellular matrix in development and morphogenesis: A dynamic view
- (2009) Tania Rozario et al. DEVELOPMENTAL BIOLOGY
- Significance of stromal desmoplasia and myofibroblast appearance at the invasive front in squamous cell carcinoma of the oral cavity
- (2009) Shuichi Kawashiri et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
- (2009) Bastian Hoechst et al. HEPATOLOGY
- Natural killer cell cytotoxicity: how do they pull the trigger?
- (2009) Nicola J. Topham et al. IMMUNOLOGY
- Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages
- (2009) Dorothée Duluc et al. INTERNATIONAL JOURNAL OF CANCER
- Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
- (2009) Matthew Oser et al. JOURNAL OF CELL BIOLOGY
- Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells
- (2009) Kyoung-Ok Hong et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells
- (2009) C. A. Corzo et al. JOURNAL OF IMMUNOLOGY
- Role of p38 MAPK Pathway in Induction of iNOS Expression in Neutrophils and Peripheral Blood Mononuclear Cells in Patients With Squamous Cell Carcinoma of the Oral Cavity
- (2009) Wioletta Ratajczak-Wrona et al. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
- (2009) Hiroshi Kurahara et al. JOURNAL OF SURGICAL RESEARCH
- Differential expression of immunohistochemical markers in bladder smooth muscle and myofibroblasts and the potential utility of desmin, smoothelin and vimentin in staging of bladder carcinoma
- (2009) Leona Council et al. MODERN PATHOLOGY
- A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the tumor and is expressing MMP-9
- (2009) Carolina M. Sterz et al. ORAL ONCOLOGY
- A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth
- (2009) Binzhi Qian et al. PLoS One
- Frequency, demographics and risk (according to tumour type or site) of cancer-associated thrombosis among patients seen at outpatient DVT clinics
- (2009) Shankaranarayana Paneesha et al. THROMBOSIS AND HAEMOSTASIS
- Platelet Chemokines in Vascular Disease
- (2008) Christian A. Gleissner et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Overview of the efficacy of cetuximab in recurrent and/or metastatic squamous cell carcinoma of the head and neck in patients who previously failed platinum-based therapies
- (2008) Jan. B. Vermorken et al. CANCER
- HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion
- (2008) Rose Du et al. CANCER CELL
- A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo
- (2008) B BLOUW et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1
- (2008) O TATTI et al. EXPERIMENTAL CELL RESEARCH
- Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries
- (2008) Shu-Chun Chuang et al. INTERNATIONAL JOURNAL OF CANCER
- Stromal myofibroblasts are drivers of invasive cancer growth
- (2008) Olivier De Wever et al. INTERNATIONAL JOURNAL OF CANCER
- RAGE signaling sustains inflammation and promotes tumor development
- (2008) Christoffer Gebhardt et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of Indoleamine 2,3-Dioxygenase in Metastatic Pancreatic Ductal Adenocarcinoma Recruits Regulatory T Cells to Avoid Immune Detection
- (2008) Agnes Witkiewicz et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase
- (2008) Sachie Hiratsuka et al. NATURE CELL BIOLOGY
- Co-culture of Head and Neck Squamous Cell Carcinoma Spheroids with Autologous Monocytes Predicts Prognosis
- (2008) K. W. Kross et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Reprogrammed Mouse Fibroblasts Differentiate into Cells of the Cardiovascular and Hematopoietic Lineages
- (2008) Katja Schenke-Layland et al. STEM CELLS
- Clinicopathologic significance of tumor cell-lined vessel and microenvironment in oral squamous cell carcinoma
- (2007) Shyun-Yeu Liu et al. ORAL ONCOLOGY
- Mutual paracrine effects of oral squamous cell carcinoma cells and normal oral fibroblasts: Induction of fibroblast to myofibroblast transdifferentiation and modulation of tumor cell proliferation
- (2007) Michele G. Kellermann et al. ORAL ONCOLOGY
- Role of metalloproteinases in platelet function
- (2007) María José Santos-Martínez et al. THROMBOSIS RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started