Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives
出版年份 2016 全文链接
标题
Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives
作者
关键词
Head and neck cancer, Human papillomavirus, Tumor microenvironment, Squamous cell carcinoma, Target therapy
出版物
CANCER AND METASTASIS REVIEWS
Volume 35, Issue 3, Pages 413-426
出版商
Springer Nature
发表日期
2016-05-18
DOI
10.1007/s10555-016-9625-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Association between Health Behaviors and a Family History of Cancer among Korean Women
- (2016) Youngsun Ham et al. Cancer Research and Treatment
- Prevalence of Human Papillomavirus in Oropharyngeal Cancer
- (2015) Andrew P. Stein et al. CANCER JOURNAL
- Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis
- (2015) Rong Zhong et al. CANCER RESEARCH
- CTLA-4+Regulatory T Cells Increased in Cetuximab-Treated Head and Neck Cancer Patients Suppress NK Cell Cytotoxicity and Correlate with Poor Prognosis
- (2015) Hyun-Bae Jie et al. CANCER RESEARCH
- Matted nodes: High distant-metastasis risk and a potential indication for intensification of systemic therapy in human papillomavirus-related oropharyngeal cancer
- (2015) Jeffrey M. Vainshtein et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Postoperative Adjuvant Lapatinib and Concurrent Chemoradiotherapy Followed by Maintenance Lapatinib Monotherapy in High-Risk Patients With Resected Squamous Cell Carcinoma of the Head and Neck: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
- (2015) Kevin Harrington et al. JOURNAL OF CLINICAL ONCOLOGY
- Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial
- (2015) Jean-Pascal H Machiels et al. LANCET ONCOLOGY
- The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study
- (2015) Richard S Finn et al. LANCET ONCOLOGY
- Rationale for combined blockade of PD-1 and CTLA-4 in advanced head and neck squamous cell cancer – Review of current data
- (2015) Mark S. Swanson et al. ORAL ONCOLOGY
- Telomere shortening in mucosa surrounding the tumor: Biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma
- (2015) Paolo Boscolo-Rizzo et al. ORAL ONCOLOGY
- A randomized, phase 2 trial of docetaxel with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer
- (2015) Antonio Jimeno et al. ORAL ONCOLOGY
- Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas
- (2015) Edmund A. Mroz et al. PLOS MEDICINE
- Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: retrospective analysis of the phase III EXTREME trial
- (2014) J. B. Vermorken et al. ANNALS OF ONCOLOGY
- A randomized, phase II trial of cetuximab with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer
- (2014) A. Jimeno et al. ANNALS OF ONCOLOGY
- TEMHEAD: a single-arm multicentre phase II study of temsirolimus in platin- and cetuximab refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) of the German SCCHN Group (AIO)†
- (2014) V. Grünwald et al. ANNALS OF ONCOLOGY
- A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck†
- (2014) T. Y. Seiwert et al. ANNALS OF ONCOLOGY
- Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences
- (2014) P Balermpas et al. BRITISH JOURNAL OF CANCER
- Distinct Subpopulations of Head and Neck Cancer Cells with Different Levels of Intracellular Reactive Oxygen Species Exhibit Diverse Stemness, Proliferation, and Chemosensitivity
- (2014) C.-W. Chang et al. CANCER RESEARCH
- Cisplatin-Induced Antitumor Immunomodulation: A Review of Preclinical and Clinical Evidence
- (2014) A. R. de Biasi et al. CLINICAL CANCER RESEARCH
- Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer
- (2014) P. J. Schuler et al. CLINICAL CANCER RESEARCH
- Phase II Clinical Trial of Multiple Peptide Vaccination for Advanced Head and Neck Cancer Patients Revealed Induction of Immune Responses and Improved OS
- (2014) Y. Yoshitake et al. CLINICAL CANCER RESEARCH
- The complement receptors CD46, CD55 and CD59 are regulated by the tumour microenvironment of head and neck cancer to facilitate escape of complement attack
- (2014) Rebecca Kesselring et al. EUROPEAN JOURNAL OF CANCER
- Association of p21-activated kinase-1 activity with aggressive tumor behavior and poor prognosis of head and neck cancer
- (2014) Jisoo Park et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Randomized Phase III Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Stage III to IV Head and Neck Carcinoma: RTOG 0522
- (2014) K. Kian Ang et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor
- (2014) Takumi Kumai et al. Journal of Translational Medicine
- Nimotuzumab provides survival benefit to patients with inoperable advanced squamous cell carcinoma of the head and neck: A randomized, open-label, phase IIb, 5-year study in Indian patients
- (2014) B.K.M. Reddy et al. ORAL ONCOLOGY
- Characterization of HPV and host genome interactions in primary head and neck cancers
- (2014) M. Parfenov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNAs in cancer: biomarkers, functions and therapy
- (2014) Josie Hayes et al. TRENDS IN MOLECULAR MEDICINE
- Clinical update on cancer: molecular oncology of head and neck cancer
- (2014) Y Suh et al. Cell Death & Disease
- ADXS-HPV: A therapeuticListeriavaccination targeting cervical cancers expressing the HPV E7 antigen
- (2014) Lori Cory et al. Human Vaccines & Immunotherapeutics
- Macrophage Regulation of Tumor Responses to Anticancer Therapies
- (2013) Michele De Palma et al. CANCER CELL
- Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8+ T cells
- (2013) Joanne Y. H. Lim et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Activation of the NOTCH Pathway in Head and Neck Cancer
- (2013) W. Sun et al. CANCER RESEARCH
- Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma
- (2013) S. Lyford-Pike et al. CANCER RESEARCH
- Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen-Specific T-cell Immunity in Head and Neck Cancer Patients
- (2013) R. M. Srivastava et al. CLINICAL CANCER RESEARCH
- T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo
- (2013) C. Geldres et al. CLINICAL CANCER RESEARCH
- Promising New Molecular Targeted Therapies in Head and Neck Cancer
- (2013) Kelly Dorsey et al. DRUGS
- Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
- (2013) K. Akagi et al. GENOME RESEARCH
- Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial
- (2013) Jan B Vermorken et al. LANCET ONCOLOGY
- Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes
- (2013) Vonn Walter et al. PLoS One
- Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation
- (2013) Simon Laban et al. RADIOTHERAPY AND ONCOLOGY
- Multi institutional phase II study of concomitant stereotactic reirradiation and cetuximab for recurrent head and neck cancer
- (2013) Eric F. Lartigau et al. RADIOTHERAPY AND ONCOLOGY
- Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers
- (2013) C. R. Pickering et al. Cancer Discovery
- Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors
- (2013) Matthias Lechner et al. Genome Medicine
- Cetuximab and bevacizumab: preclinical data and phase II trial in recurrent or metastatic squamous cell carcinoma of the head and neck
- (2012) A. Argiris et al. ANNALS OF ONCOLOGY
- PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
- (2012) C. Badoual et al. CANCER RESEARCH
- Dose-Dense Chemotherapy Improves Mechanisms of Antitumor Immune Response
- (2012) C.-L. Chang et al. CANCER RESEARCH
- mTOR Inhibitors and its Role in the Treatment of Head and Neck Squamous Cell Carcinoma
- (2012) Shaun A. Nguyen et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- p53 mutations in cancer
- (2012) Patricia A. J. Muller et al. NATURE CELL BIOLOGY
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human papillomavirus related head and neck cancer survival: A systematic review and meta-analysis
- (2012) M.A. O’Rorke et al. ORAL ONCOLOGY
- Cancer Stem Cells as a Predictive Factor in Radiotherapy
- (2012) Thomas B. Brunner et al. SEMINARS IN RADIATION ONCOLOGY
- Functional organ preservation in patients with locoregionally advanced head and neck squamous cell carcinoma treated by platinum-based multidrug induction chemotherapy and concurrent chemoradiotherapy
- (2011) P. Boscolo-Rizzo et al. ANNALS OF ONCOLOGY
- Phase II study of the combination of cetuximab and weekly paclitaxel in the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of head and neck
- (2011) R. Hitt et al. ANNALS OF ONCOLOGY
- The Immunological Impact of Neoadjuvant Chemotherapy on the Tumor Microenvironment of Esophageal Squamous Cell Carcinoma
- (2011) Takahiro Tsuchikawa et al. ANNALS OF SURGICAL ONCOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Functional mutation analysis of EGFR family genes and corresponding lymph node metastases in head and neck squamous cell carcinoma
- (2011) Takanori Hama et al. CLINICAL & EXPERIMENTAL METASTASIS
- TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
- (2011) H. D. Skinner et al. CLINICAL CANCER RESEARCH
- Phase II Trial of Pemetrexed and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer
- (2011) Athanassios Argiris et al. JOURNAL OF CLINICAL ONCOLOGY
- Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial
- (2011) Jean-Pascal Machiels et al. LANCET ONCOLOGY
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1
- (2011) N. Agrawal et al. SCIENCE
- The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
- (2011) N. Stransky et al. SCIENCE
- MicroRNA expression profiles of head and neck squamous cell carcinoma with docetaxel-induced multidrug resistance
- (2010) Yuemeng Dai et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- TP53Mutations and Pathologic Complete Response to Neoadjuvant Cisplatin and Fluorouracil Chemotherapy in Resected Oral Cavity Squamous Cell Carcinoma
- (2010) Federica Perrone et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Evaluation of Sorafenib in Advanced and Metastatic Squamous Cell Carcinoma of the Head and Neck: Southwest Oncology Group Study S0420
- (2010) Stephen K. Williamson et al. JOURNAL OF CLINICAL ONCOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Changes in Survival in Head and Neck Cancers in the Late 20th and Early 21st Century: A Period Analysis
- (2010) D. Pulte et al. ONCOLOGIST
- Overexpression of macrophage inflammatory protein-3α in oral cavity squamous cell carcinoma is associated with nodal metastasis
- (2010) Kai-Ping Chang et al. ORAL ONCOLOGY
- Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
- (2009) C Alfaro et al. BRITISH JOURNAL OF CANCER
- The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies
- (2009) J. Ozao-Choy et al. CANCER RESEARCH
- A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis
- (2009) Maddalena Adorno et al. CELL
- Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck
- (2009) J. Nemunaitis et al. CLINICAL CANCER RESEARCH
- Role of macrophages in tumour progression
- (2009) K.S. Siveen et al. IMMUNOLOGY LETTERS
- Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study
- (2009) Ezra EW Cohen et al. LANCET ONCOLOGY
- Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
- (2009) James A Bonner et al. LANCET ONCOLOGY
- Combined Inhibition of PLC -1 and c-Src Abrogates Epidermal Growth Factor Receptor-Mediated Head and Neck Squamous Cell Carcinoma Invasion
- (2008) H. Nozawa et al. CLINICAL CANCER RESEARCH
- Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma
- (2008) P. Koppikar et al. CLINICAL CANCER RESEARCH
- Therapeutic human papillomavirus vaccines: current clinical trials and future directions
- (2008) Chien-Fu Hung et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer
- (2008) Jan B. Vermorken et al. NEW ENGLAND JOURNAL OF MEDICINE
- let-7 microRNAs in development, stem cells and cancer
- (2008) Ingo Büssing et al. TRENDS IN MOLECULAR MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search