标题
Mass production of functional human pancreatic β-cells: why and how?
作者
关键词
-
出版物
DIABETES OBESITY & METABOLISM
Volume 18, Issue -, Pages 128-136
出版商
Wiley
发表日期
2016-09-12
DOI
10.1111/dom.12728
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation
- (2016) Karine Robitaille et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Xenotropic retrovirus Bxv1 in human pancreatic β cell lines
- (2016) Jeannette S. Kirkegaard et al. JOURNAL OF CLINICAL INVESTIGATION
- Human pancreatic beta-like cells converted from fibroblasts
- (2016) Saiyong Zhu et al. Nature Communications
- Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells
- (2016) Vikash Chandra et al. Scientific Reports
- MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes
- (2016) Elvira Ganic et al. Cell Reports
- GPR44 is a pancreatic protein restricted to the human beta cell
- (2015) Ewa Hellström-Lindahl et al. ACTA DIABETOLOGICA
- Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles
- (2015) Nora S. Kayton et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines
- (2015) Bryndon J. Oleson et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Differentiation of human pluripotent stem cells into β-cells: Potential and challenges
- (2015) Nina Quiskamp et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Brusatol inhibits the response of cultured beta-cells to pro-inflammatory cytokines in vitro
- (2015) Kyril Turpaev et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Physiological characterization of the human EndoC-βH1 β-cell line
- (2015) Ewa Gurgul-Convey et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Analysis artefacts of the INS-IGF2 fusion transcript
- (2015) Rasmus Wernersson et al. BMC MOLECULAR BIOLOGY
- Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells
- (2015) Rikard G. Fred et al. CLINICAL SCIENCE
- Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells
- (2015) Leena Paul et al. DIABETES
- Loss-of-Function Mutations in the Cell-Cycle Control GeneCDKN2AImpact on Glucose Homeostasis in Humans
- (2015) Aparna Pal et al. DIABETES
- MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function
- (2015) David W. Scoville et al. DIABETES
- TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells
- (2015) Laura Marroqui et al. DIABETES
- Pancreatic β-cell imaging in humans: fiction or option?
- (2015) D. Laurent et al. DIABETES OBESITY & METABOLISM
- The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro
- (2015) Kira Meyerovich et al. DIABETOLOGIA
- Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms
- (2015) Flora Brozzi et al. DIABETOLOGIA
- Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy
- (2015) Cornelis R. van der Torren et al. DIABETOLOGIA
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- DNA methylation directs functional maturation of pancreatic β cells
- (2015) Sangeeta Dhawan et al. JOURNAL OF CLINICAL INVESTIGATION
- Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes
- (2015) Marcela Brissova et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death
- (2015) Rikard G. Fred et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
- (2015) Kyle J Gaulton et al. NATURE GENETICS
- Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
- (2015) Cong Tang et al. NATURE MEDICINE
- Calcium Signaling in a Genetically Engineered Human Pancreatic β-Cell Line
- (2015) Kalaiselvan Krishnan et al. PANCREAS
- Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells
- (2015) Brian McKenna et al. Cell Reports
- Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice
- (2015) Jennifer E. Bruin et al. Stem Cell Reports
- A human beta cell line with drug inducible excision of immortalizing transgenes
- (2015) Marion Benazra et al. Molecular Metabolism
- Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line
- (2015) Lotta E. Andersson et al. PLoS One
- Composition and function of macroencapsulated human embryonic stem cell-derived implants: comparison with clinical human islet cell grafts
- (2014) Evi Motté et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- BACH2, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic -Cells via JNK1 Modulation and Crosstalk With the Candidate Gene PTPN2
- (2014) L. Marroqui et al. DIABETES
- Summary of the Keystone Islet Workshop (April 2014): The Increasing Demand for Human Islet Availability in Diabetes Research
- (2014) R. N. Kulkarni et al. DIABETES
- A Combined “Omics” Approach Identifies N-Myc Interactor as a Novel Cytokine-induced Regulator of IRE1α Protein and c-Jun N-terminal Kinase in Pancreatic Beta Cells
- (2014) Flora Brozzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?
- (2014) Dhananjay Gupta et al. JOURNAL OF CLINICAL INVESTIGATION
- Development of a conditionally immortalized human pancreatic β cell line
- (2014) Raphaël Scharfmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
- Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
- (2014) Lorenzo Pasquali et al. NATURE GENETICS
- Human Fucci Pancreatic Beta Cell Lines: New Tools to Study Beta Cell Cycle and Terminal Differentiation
- (2014) Géraldine Carlier et al. PLoS One
- RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells
- (2014) Vikash Chandra et al. Cell Reports
- Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4
- (2013) Srividya Vasu et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4
- (2013) Srividya Vasu et al. BIOLOGICAL CHEMISTRY
- Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistancein vivoand cause pancreatic β-cell dysfunction and deathin vitro
- (2013) Mauricio Krause et al. CLINICAL SCIENCE
- How to make a functional -cell
- (2013) F. W. Pagliuca et al. DEVELOPMENT
- Mouse Muscle As an Ectopic Permissive Site for Human Pancreatic Development
- (2013) C. Capito et al. DIABETES
- Insulin Resistance Alters Islet Morphology in Nondiabetic Humans
- (2013) T. Mezza et al. DIABETES
- IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets
- (2013) Fabio A. Grieco et al. DIABETOLOGIA
- Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5′-phosphatase interaction with c-Abl
- (2013) D. Mokhtari et al. DIABETOLOGIA
- An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans
- (2013) Stefan Amisten et al. PHARMACOLOGY & THERAPEUTICS
- Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells
- (2013) Mark A. Russell et al. Islets
- Kisspeptin Prevention of Amyloid-β Peptide Neurotoxicity in Vitro
- (2012) Nathaniel G. N. Milton et al. ACS Chemical Neuroscience
- Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes
- (2012) Ignasi Morán et al. Cell Metabolism
- Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility
- (2012) Hong Guo-Parke et al. JOURNAL OF ENDOCRINOLOGY
- Paracrine and autocrine interactions in the human islet: More than meets the eye
- (2012) Alejandro Caicedo SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Concise Review: In Search of Unlimited Sources of Functional Human Pancreatic Beta Cells
- (2012) Raphael Scharfmann et al. Stem Cells Translational Medicine
- Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas
- (2011) Rayner Rodriguez-Diaz et al. Cell Metabolism
- Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3
- (2011) O. Rubio-Cabezas et al. DIABETES
- Transcriptomes of the major human pancreatic cell types
- (2011) C. Dorrell et al. DIABETOLOGIA
- Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets
- (2011) C. Dai et al. DIABETOLOGIA
- Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion
- (2011) Jane T. McCluskey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion
- (2011) Philippe Ravassard et al. JOURNAL OF CLINICAL INVESTIGATION
- The Stunned β Cell: A Brief History
- (2010) Ele Ferrannini Cell Metabolism
- Rfx6 directs islet formation and insulin production in mice and humans
- (2010) Stuart B. Smith et al. NATURE
- A New Strategy to Generate Functional Insulin-Producing Cell Lines by Somatic Gene Transfer into Pancreatic Progenitors
- (2009) Philippe Ravassard et al. PLoS One
- Pancreatic Duct Cells in Human Islet Cell Preparations Are a Source of Angiogenic Cytokines Interleukin-8 and Vascular Endothelial Growth Factor
- (2008) B. Movahedi et al. DIABETES
- Voltage-Gated Ion Channels in Human Pancreatic -Cells: Electrophysiological Characterization and Role in Insulin Secretion
- (2008) M. Braun et al. DIABETES
- Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
- (2008) Evert Kroon et al. NATURE BIOTECHNOLOGY
- Beta Cells within Single Human Islets Originate from Multiple Progenitors
- (2008) Raphaël Scharfmann et al. PLoS One
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started