Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistancein vivoand cause pancreatic β-cell dysfunction and deathin vitro

TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses

(2013) H. B. Cohen et al.   BLOOD

Glutaredoxin-2 Is Required to Control Proton Leak through Uncoupling Protein-3

(2013) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet Ca2+ responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca2+ stores

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Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?

(2012) Josianne Rodrigues-Krause et al.   CELL STRESS & CHAPERONES

Physiological, pathological and potential therapeutic roles of adipokines

(2012) Inês Falcão-Pires et al.   DRUG DISCOVERY TODAY

Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: a critical role for amino acids

(2012) P Newsholme et al.   JOURNAL OF ENDOCRINOLOGY

Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets

(2012) Mauricio da Silva Krause et al.   JOURNAL OF ENDOCRINOLOGY

Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: a preliminary study

(2012) Mauricio Krause et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people

(2011) Kishiko Ogawa et al.   CELL STRESS & CHAPERONES

Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion

(2011) Jane T. McCluskey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

(2011) Mauricio S Krause et al.   JOURNAL OF ENDOCRINOLOGY

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

Increased serum HSP70 levels are associated with the duration of diabetes

(2010) Manouchehr Nakhjavani et al.   CELL STRESS & CHAPERONES

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extracellular heat shock proteins (eHSP70) in exercise: Possible targets outside the immune system and their role for neurodegenerative disorders treatment

(2010) Mauricio Krause et al.   MEDICAL HYPOTHESES

Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: the central role of ROS and nitric oxide

(2009) Philip Newsholme et al.   CLINICAL SCIENCE

Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium

(2009) P. Concannon et al.   DIABETES

Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 β-cell insulin secretion and signal transduction

(2009) Aoife Kiely et al.   JOURNAL OF ENDOCRINOLOGY

The role of systemic inflammation in age-related muscle weakness and wasting

(2009) H. Degens   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

The on-off switches of the mitochondrial uncoupling proteins

(2009) Vian Azzu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heat shock proteins and exercise: a primer

(2008) Earl G. Noble et al.   Applied Physiology Nutrition and Metabolism

Oxidized Phospholipid Inhibition of Toll-like Receptor (TLR) Signaling Is Restricted to TLR2 and TLR4

(2008) Clett Erridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSP72 protects against obesity-induced insulin resistance

(2008) J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of stress-inducible extracellular Hsp72 on human neutrophil chemotaxis: A role during acute intense exercise

(2008) Eduardo Ortega et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion

(2007) Charles Affourtit et al.   BIOCHEMICAL JOURNAL

Heat shock protein 72 : release and biological significance during exercise

(2007) Martin Whitham   Frontiers in Bioscience-Landmark