Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model
出版年份 2020 全文链接
标题
Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model
作者
关键词
Ferroptosis inhibitor, Structure-activity relationship, Ischemic stroke, Promethazine derivatives
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 209, Issue -, Pages 112842
出版商
Elsevier BV
发表日期
2020-09-18
DOI
10.1016/j.ejmech.2020.112842
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- N 10 ‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress
- (2019) Robert G. Keynes et al. Chemical Biology & Drug Design
- Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes
- (2018) Yuichi Baba et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- ENPP2 protects cardiomyocytes from erastin-induced ferroptosis
- (2018) Yu-Ting Bai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
- (2017) Q-z Tuo et al. MOLECULAR PSYCHIATRY
- Ferroptosis and cell death mechanisms in Parkinson's disease
- (2017) Stephanie J. Guiney et al. NEUROCHEMISTRY INTERNATIONAL
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
- (2017) William Sealy Hambright et al. Redox Biology
- Identification of baicalein as a ferroptosis inhibitor by natural product library screening
- (2016) Yangchun Xie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- Mechanisms of ferroptosis
- (2016) Jennifer Yinuo Cao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties
- (2016) Sam Hofmans et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI
- (2016) Diego Martin-Sanchez et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC
- (2016) Bruce Do Van et al. NEUROBIOLOGY OF DISEASE
- Ferroptosis: a novel cell death form will be a promising therapy target for diseases
- (2015) Di Wu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
- (2015) Yang Liu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
- (2015) Xiaofang Sun et al. HEPATOLOGY
- T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
- (2015) Mai Matsushita et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Ferroptosis is Involved in Acetaminophen Induced Cell Death
- (2015) Tamás Lőrincz et al. PATHOLOGY & ONCOLOGY RESEARCH
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Synchronized renal tubular cell death involves ferroptosis
- (2014) Andreas Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke
- (2013) Rachel E. Speer et al. FREE RADICAL BIOLOGY AND MEDICINE
- Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
- (2013) A. Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Cerebral ischemia: Models, methods and outcomes
- (2007) Konstantin-Alexander Hossmann NEUROPHARMACOLOGY
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