标题
Mechanisms of ferroptosis
作者
关键词
Cell death, Iron, Reactive oxygen species, Glutathione, Cancer, RAS, Glutathione peroxidase 4, Erastin, Sorafenib, Ferrostatin-1, Polyunsaturated fatty acid
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 11-12, Pages 2195-2209
出版商
Springer Nature
发表日期
2016-04-05
DOI
10.1007/s00018-016-2194-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- Mammalian lipoxygenases and their biological relevance
- (2015) Hartmut Kuhn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
- (2015) Yang Liu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
- (2015) Isaac S. Harris et al. CANCER CELL
- Elucidating Compound Mechanism of Action by Network Perturbation Analysis
- (2015) Jung Hoon Woo et al. CELL
- T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
- (2015) Mai Matsushita et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Ferroptosis as a p53-mediated activity during tumour suppression
- (2015) Le Jiang et al. NATURE
- Ferroptosis is Involved in Acetaminophen Induced Cell Death
- (2015) Tamás Lőrincz et al. PATHOLOGY & ONCOLOGY RESEARCH
- Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death
- (2015) Christina Schott et al. Frontiers in Oncology
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Measuring Glutathione Redox Potential of HIV-1-infected Macrophages
- (2014) Ashima Bhaskar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death
- (2014) H Schoeneberger et al. ONCOGENE
- Synchronized renal tubular cell death involves ferroptosis
- (2014) Andreas Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic control of cell death
- (2014) D. R. Green et al. SCIENCE
- Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
- (2014) Mary Ann Allen et al. eLife
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
- (2013) D. Kenzelmann Broz et al. GENES & DEVELOPMENT
- Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib
- (2013) Christophe Louandre et al. INTERNATIONAL JOURNAL OF CANCER
- The role of iron and reactive oxygen species in cell death
- (2013) Scott J Dixon et al. Nature Chemical Biology
- Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
- (2013) Y. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
- (2013) N Henke et al. Cell Death & Disease
- Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
- (2012) Tongyuan Li et al. CELL
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Mechanisms of Oxidative Glutamate Toxicity: The Glutamate/Cystine Antiporter System xc¯ as a Neuroprotective Drug Target
- (2012) Philipp Albrecht et al. CNS & Neurological Disorders-Drug Targets
- Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo
- (2012) R. Coriat et al. MOLECULAR CANCER THERAPEUTICS
- The pantheon of the fallen: why are there so many forms of cell death?
- (2012) Douglas R. Green et al. TRENDS IN CELL BIOLOGY
- Functional Model of Metabolite Gating by Human Voltage-Dependent Anion Channel 2
- (2011) Andras J. Bauer et al. BIOCHEMISTRY
- Development of small-molecule probes that selectively kill cells induced to express mutant RAS
- (2011) Michel Weïwer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression
- (2011) Colleen A. Brady et al. CELL
- Programmed Cell Death in Animal Development and Disease
- (2011) Yaron Fuchs et al. CELL
- Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
- (2011) A. T. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulatory profiling identifies mechanisms of small molecule-induced cell death
- (2011) A. J. Wolpaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons
- (2010) S Tobaben et al. CELL DEATH AND DIFFERENTIATION
- System xc−and Thioredoxin Reductase 1 Cooperatively Rescue Glutathione Deficiency
- (2010) Pankaj Kumar Mandal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glutathione Depletion by Buthionine Sulfoximine Induces Oxidative Damage to DNA in Organs of Rabbits in Vivo
- (2009) Goksel Gokce et al. BIOCHEMISTRY
- Apoptosis and glutathione: beyond an antioxidant
- (2009) R Franco et al. CELL DEATH AND DIFFERENTIATION
- Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
- (2009) A. Siddiq et al. JOURNAL OF NEUROSCIENCE
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Mammalian Long-Chain Acyl-CoA Synthetases
- (2008) Eric Soupene et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation
- (2008) Claus Schneider et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acyl-CoA:Lysophospholipid Acyltransferases
- (2008) Hideo Shindou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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