Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9-mediated HDR in Atlantic salmon

(2020) Anne Hege Straume et al.   Scientific Reports

CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes

(2019) Alex K. Datsomor et al.   Scientific Reports

CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)

(2019) Alex K. Datsomor et al.   Scientific Reports

Life-stage-associated remodelling of lipid metabolism regulation in Atlantic salmon

(2018) Gareth Gillard et al.   MOLECULAR ECOLOGY

A systemic study of lipid metabolism regulation in salmon fingerlings and early juveniles fed plant oil

(2018) Yang Jin et al.   BRITISH JOURNAL OF NUTRITION

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine

(2016) Maximilian W. Popp et al.   CELL

Regulatory divergence of homeologous Atlantic salmon elovl5 genes following the salmonid-specific whole-genome duplication

(2016) Greta Carmona-Antoñanzas et al.   GENE

Random Splicing of Several Exons Caused by a Single Base Change in the Target Exon of CRISPR/Cas9 Mediated Gene Knockout

(2016) Marcel Kapahnke et al.   Cells

Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

(2016) Anna Wargelius et al.   Scientific Reports

Impact of sustainable feeds on omega-3 long-chain fatty acid levels in farmed Atlantic salmon, 2006–2015

(2016) M. Sprague et al.   Scientific Reports

Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective

(2015) Douglas R. Tocher   AQUACULTURE

Utilisation of feed resources in production of Atlantic salmon (Salmo salar) in Norway

(2015) Trine Ytrestøyl et al.   AQUACULTURE

Targeted Mutagenesis in Atlantic Salmon (Salmo salar L.) Using the CRISPR/Cas9 System Induces Complete Knockout Individuals in the F0 Generation

(2014) Rolf B. Edvardsen et al.   PLoS One

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

High levels of dietary phytosterols affect lipid metabolism and increase liver and plasma TAG in Atlantic salmon (Salmo salar L.)

(2013) Nina S. Liland et al.   BRITISH JOURNAL OF NUTRITION

Conservation of lipid metabolic gene transcriptional regulatory networks in fish and mammals

(2013) Greta Carmona-Antoñanzas et al.   GENE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Hepatic transcriptome analysis of inter-family variability in flesh n-3 long-chain polyunsaturated fatty acid content in Atlantic salmon

(2012) Sofia Morais et al.   BMC GENOMICS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Detecting differential usage of exons from RNA-seq data

(2012) S. Anders et al.   GENOME RESEARCH

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genotype-specific responses in Atlantic salmon (Salmo salar) subject to dietary fish oil replacement by vegetable oil: a liver transcriptomic analysis

(2011) Sofia Morais et al.   BMC GENOMICS

Biosynthesis of very long-chain fatty acids (C>24) in Atlantic salmon: Cloning, functional characterisation, and tissue distribution of an Elovl4 elongase

(2011) Greta Carmona-Antoñanzas et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Multiple genes for functional ∆6 fatty acyl desaturases (Fad) in Atlantic salmon (Salmo salar L.): Gene and cDNA characterization, functional expression, tissue distribution and nutritional regulation

(2010) Óscar Monroig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Chemical Composition and Oxidative Stability of Selected Plant Oils

(2010) Arkadiusz Szterk et al.   JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Highly Unsaturated Fatty Acid Synthesis in Atlantic Salmon: Characterization of ELOVL5- and ELOVL2-like Elongases

(2009) Sofia Morais et al.   MARINE BIOTECHNOLOGY

Regulation of hepatic fatty acid elongase 5 by LXRα–SREBP-1c

(2008) Yan Qin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar)

(2008) Michael J Leaver et al.   BMC GENOMICS