标题
ANTs and cancer: Emerging pathogenesis, mechanisms, and perspectives
作者
关键词
ANTs, ADP/ATP transporter, mPTP, Carcinogenesis, Targeted therapy
出版物
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1875, Issue 1, Pages 188485
出版商
Elsevier BV
发表日期
2020-12-12
DOI
10.1016/j.bbcan.2020.188485
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death
- (2020) Tyler M. Bauer et al. CIRCULATION RESEARCH
- ROS-mediated miR-21-5p regulates the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4
- (2020) Yujing Zhang et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier
- (2019) Jonathan J. Ruprecht et al. CELL
- Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
- (2019) Rumani Singh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition
- (2019) Jessica Gräb et al. Nature Communications
- H+ transport is an integral function of the mitochondrial ADP/ATP carrier
- (2019) Ambre M. Bertholet et al. NATURE
- Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
- (2019) Gang Cheng et al. Nature Communications
- Antitumor Effect of Lonidamine-Polypeptide-Peptide Nanoparticles in Breast Cancer Models
- (2019) Ifat Cohen-Erez et al. ACS Applied Materials & Interfaces
- Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier
- (2019) Jonathan J Ruprecht et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD
- (2019) Jason Karch et al. Science Advances
- The ADP/ATP translocase drives mitophagy independent of nucleotide exchange
- (2019) Atsushi Hoshino et al. NATURE
- The SLC25 Mitochondrial Carrier Family: Structure and Mechanism
- (2019) Jonathan J. Ruprecht et al. TRENDS IN BIOCHEMICAL SCIENCES
- Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy
- (2019) Ali F. Abdel-Wahab et al. PHARMACOLOGICAL RESEARCH
- Dominant and sensitive control of oxidative flux by the ATP-ADP carrier in human skeletal muscle mitochondria: Effect of lysine acetylation
- (2018) W.T. Willis et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
- (2018) Sona Hubackova et al. CELL DEATH AND DIFFERENTIATION
- AMPK: Sensing Glucose as well as Cellular Energy Status
- (2018) Sheng-Cai Lin et al. Cell Metabolism
- Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
- (2018) Sarah Pickles et al. CURRENT BIOLOGY
- Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim
- (2018) Suresh Banjara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effective platinum(IV) prodrugs conjugated with lonidamine as a functional group working on the mitochondria
- (2018) Hong Chen et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?
- (2018) Natalia Prevarskaya et al. PHYSIOLOGICAL REVIEWS
- Neuronal Cell Death
- (2018) Michael Fricker et al. PHYSIOLOGICAL REVIEWS
- Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions
- (2018) David Bargiela et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- DNMT1 mediates metabolic reprogramming induced by Epstein–Barr virus latent membrane protein 1 and reversed by grifolin in nasopharyngeal carcinoma
- (2018) Xiangjian Luo et al. Cell Death & Disease
- Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells
- (2018) Rong Zhang et al. Cell Death & Disease
- BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose
- (2018) Federico Lucantoni et al. Oncotarget
- Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy
- (2018) Meagan J. McManus et al. Cell Metabolism
- Mitochondrial permeability transition pore: a potential drug target for neurodegeneration
- (2018) Komal Kalani et al. DRUG DISCOVERY TODAY
- Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition
- (2018) Anibal E. Vercesi et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Different Routes to Metastasis via Hypoxia-Regulated Programs
- (2018) Ana Rita Nobre et al. TRENDS IN CELL BIOLOGY
- Mitochondrial ADP Sensitivity and Transport: New Insights Into Diet-Induced Mitochondrial Impairments
- (2018) Corey R. Hart et al. DIABETES
- ANT2 mediates hypoxia and inflammation in obesity
- (2018) Isobel Leake Nature Reviews Endocrinology
- Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets
- (2018) Thomas Briston et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Screening of candidate substrates and coupling ions of transporters by thermostability shift assays
- (2018) Homa Majd et al. eLife
- CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity
- (2017) Xiali Zhong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
- (2017) Daniel Garcia et al. MOLECULAR CELL
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging
- (2017) Ying Wang et al. NEUROPHARMACOLOGY
- Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis
- (2017) Wenjie Guo et al. Nature Communications
- Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
- (2017) Joonseok Cho et al. Nature Communications
- Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions
- (2017) Chen Zhang et al. Scientific Reports
- The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1
- (2017) Li Xiao et al. Redox Biology
- Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
- (2016) Kyle Thompson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Shared Molecular Mechanisms of Membrane Transporters
- (2016) David Drew et al. Annual Review of Biochemistry
- Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine
- (2016) Y. D. Bhutia et al. BIOCHEMICAL JOURNAL
- Identification of new highly selective inhibitors of the human ADP/ATP carriers by molecular docking and in vitro transport assays
- (2016) Simona Todisco et al. BIOCHEMICAL PHARMACOLOGY
- The transport mechanism of the mitochondrial ADP/ATP carrier
- (2016) Edmund R.S. Kunji et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival
- (2016) Rigel J. Kishton et al. Cell Metabolism
- Energy metabolic alterations in the progression of atrial fibrillation: Potential role of AMP-activated protein kinase as a critical regulator
- (2016) Jie Qiu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Targeting Adenine Nucleotide Translocase-2 (ANT2) to Overcome Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Non–Small Cell Lung Cancer
- (2016) Ji-Young Jang et al. MOLECULAR CANCER THERAPEUTICS
- To involvement the conformation of the adenine nucleotide translocase in opening the Tl+-induced permeability transition pore in Ca2+-loaded rat liver mitochondria
- (2016) Sergey M. Korotkov et al. TOXICOLOGY IN VITRO
- Deciphering the Molecular Signals of PINK1/Parkin Mitophagy
- (2016) Thanh N. Nguyen et al. TRENDS IN CELL BIOLOGY
- Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties
- (2016) Valentina Izzo et al. TRENDS IN CELL BIOLOGY
- ABT-737 sensitizes curcumin-induced anti-melanoma cell activity through facilitating mPTP death pathway
- (2015) Teng Yu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis
- (2015) J Cho et al. CELL DEATH AND DIFFERENTIATION
- Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications
- (2015) Rebecca Kohnken et al. Molecular Cancer
- AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest
- (2015) Elena Doménech et al. NATURE CELL BIOLOGY
- Adenine Nucleotide Translocase Is Acetylated in Vivo in Human Muscle: Modeling Predicts a Decreased ADP Affinity and Altered Control of Oxidative Phosphorylation
- (2014) Clinton Mielke et al. BIOCHEMISTRY
- MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
- (2014) Helge Gad et al. NATURE
- Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism
- (2014) J. J. Ruprecht et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic control of cell death
- (2014) D. R. Green et al. SCIENCE
- Mitochondrial permeability transition pore is a potential drug target for neurodegeneration
- (2013) Valasani Koteswara Rao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The mitochondrial ADP/ATP carrier (SLC25 family): Pathological implications of its dysfunction
- (2013) Benjamin Clémençon et al. MOLECULAR ASPECTS OF MEDICINE
- Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway
- (2013) Wei-jia Wang et al. Nature Chemical Biology
- Adenine Nucleotide Translocase, Mitochondrial Stress, and Degenerative Cell Death
- (2013) Yaxin Liu et al. Oxidative Medicine and Cellular Longevity
- The substrate specificity of the human ADP/ATP carrier AAC1
- (2012) John Mifsud et al. MOLECULAR MEMBRANE BIOLOGY
- Adenine nucleotide transporters in organelles: novel genes and functions
- (2011) Javier Traba et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Adenine Nucleotide Translocase 2, a Mitochondrial Target for Anticancer Biotherapy
- (2011) Ossama Sharaf el dein et al. CURRENT DRUG TARGETS
- A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection
- (2010) Andrew P. Halestrap BIOCHEMICAL SOCIETY TRANSACTIONS
- Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism
- (2010) Arnaud Chevrollier et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Coupling of proton and substrate translocation in the transport cycle of mitochondrial carriers
- (2010) Edmund RS Kunji et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Adenine nucleotide translocase family: four isoforms for apoptosis modulation in cancer
- (2010) C Brenner et al. ONCOGENE
- Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria
- (2009) Jianhua Feng et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis
- (2009) Vijay P. Singh et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis
- (2009) W Malorni et al. CELL DEATH AND DIFFERENTIATION
- Over-expression of Adenine Nucleotide Translocase 1 (ANT1) Induces Apoptosis and Tumor Regression in vivo
- (2008) Ji-Young Jang et al. BMC CANCER
- The mechanism of transport by mitochondrial carriers based on analysis of symmetry
- (2008) A. J. Robinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The product of the Herpes simplex virus 1 UL7 gene interacts with a mitochondrial protein, adenine nucleotide translocator 2
- (2008) Michiko Tanaka et al. Virology Journal
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now