The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease
出版年份 2021 全文链接
标题
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease
作者
关键词
-
出版物
ACTA NEUROPATHOLOGICA
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-01-11
DOI
10.1007/s00401-020-02248-1
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade
- (2020) Fang Zhang et al. Science Translational Medicine
- Brainstem Volumetric Integrity in Preclinical and Prodromal Alzheimer’s Disease
- (2020) Shubir Dutt et al. JOURNAL OF ALZHEIMERS DISEASE
- Locus coeruleus: a new look at the blue spot
- (2020) Gina R. Poe et al. NATURE REVIEWS NEUROSCIENCE
- Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases
- (2019) Matthew J Betts et al. BRAIN
- Locus Coeruleus Degeneration Induces Forebrain Vascular Pathology in a Transgenic Rat Model of Alzheimer’s Disease
- (2019) Sarah C. Kelly et al. JOURNAL OF ALZHEIMERS DISEASE
- Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s disease
- (2019) Pauline Olivieri et al. Annals of Clinical and Translational Neurology
- Axonal projection‐specific differences in somatodendritic α2 autoreceptor function in locus coeruleus neurons
- (2019) Tobias A. Wagner‐Altendorf et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling
- (2019) Yong U. Liu et al. NATURE NEUROSCIENCE
- Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus
- (2019) Seong Su Kang et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of Deep Brain Stimulation of the ventromedial prefrontal cortex on the noradrenergic system in rats
- (2018) Sonia Torres-Sanchez et al. Brain Stimulation
- Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans
- (2018) Panos Theofilas et al. NEUROBIOLOGY OF AGING
- The spectrum of preclinical Alzheimer’s pathology and its modulation by ApoE genotype
- (2018) Olga Pletnikova et al. NEUROBIOLOGY OF AGING
- Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease
- (2018) David Weinshenker TRENDS IN NEUROSCIENCES
- Brain Stimulation in Alzheimer's Disease
- (2018) Chun-Hung Chang et al. Frontiers in Psychiatry
- The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders
- (2018) Teresa H. Wen et al. Frontiers in Molecular Neuroscience
- Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice
- (2017) Termpanit Chalermpalanupap et al. JOURNAL OF NEUROSCIENCE
- Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq
- (2017) Cathryn R Cadwell et al. Nature Protocols
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease
- (2017) A. J. Ehrenberg et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Locus coeruleus at asymptomatic early and middle Braak stages of neurofibrillary tangle pathology
- (2017) P. Andrés-Benito et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Monoaminergic neuropathology in Alzheimer’s disease
- (2017) Goran Šimić et al. PROGRESS IN NEUROBIOLOGY
- Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease
- (2017) Fabio A. Zucca et al. PROGRESS IN NEUROBIOLOGY
- The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease
- (2017) Filippo S. Giorgi et al. Frontiers in Neuroanatomy
- Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease
- (2017) Sarah C. Kelly et al. Acta Neuropathologica Communications
- Roles of tau pathology in the locus coeruleus (LC) in age-associated pathophysiology and Alzheimer’s disease pathogenesis: Potential strategies to protect the LC against aging
- (2017) Akiko Satoh et al. BRAIN RESEARCH
- Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly
- (2016) Mayelín Domínguez et al. FREE RADICAL BIOLOGY AND MEDICINE
- Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system
- (2016) Douglas L. Feinstein et al. JOURNAL OF NEUROCHEMISTRY
- The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain
- (2016) Mara Mather et al. TRENDS IN COGNITIVE SCIENCES
- Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer’s disease
- (2015) Csaba Ádori et al. ACTA NEUROPATHOLOGICA
- Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology
- (2015) Katharina Stratmann et al. BRAIN PATHOLOGY
- Noradrenergic System in Down Syndrome and Alzheimer's Disease A Target for Therapy
- (2015) Cristy Phillips et al. Current Alzheimer Research
- Organization of the Locus Coeruleus-Norepinephrine System
- (2015) Lindsay A. Schwarz et al. CURRENT BIOLOGY
- 7,8-Dihydroxyflavone as a pro-neurotrophic treatment for neurodevelopmental disorders
- (2015) X. Du et al. NEUROCHEMISTRY INTERNATIONAL
- Early neurone loss in Alzheimer’s disease: cortical or subcortical?
- (2015) Thomas Arendt et al. Acta Neuropathologica Communications
- Locus (Coeruleus) Minoris Resistentiae in Pathogenesis of Alzheimer’s Disease
- (2014) Boris Mravec et al. Current Alzheimer Research
- Noradrenergic Regulation of Glial Activation: Molecular Mechanisms and Therapeutic Implications
- (2014) David Braun et al. Current Neuropharmacology
- Norepinephrine deficiency in Parkinson's disease: The case for noradrenergic enhancement
- (2014) Alberto J. Espay et al. MOVEMENT DISORDERS
- Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase
- (2014) Javier Sanchez-Padilla et al. NATURE NEUROSCIENCE
- Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease
- (2013) M.-Marsel Mesulam JOURNAL OF COMPARATIVE NEUROLOGY
- Functional neuroanatomy of the central noradrenergic system
- (2013) Elemer Szabadi JOURNAL OF PSYCHOPHARMACOLOGY
- Uptake of environmental toxicants by the locus ceruleus: A potential trigger for neurodegenerative, demyelinating and psychiatric disorders
- (2013) Roger Pamphlett MEDICAL HYPOTHESES
- 7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer’s Disease
- (2013) Zhentao Zhang et al. NEUROPSYCHOPHARMACOLOGY
- Ascending monoaminergic systems alterations in Alzheimer's disease. Translating basic science into clinical care
- (2013) Ludwig Trillo et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe
- (2013) E. Le Maitre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective Loss of Noradrenaline Exacerbates Early Cognitive Dysfunction and Synaptic Deficits in APP/PS1 Mice
- (2012) Thea Hammerschmidt et al. BIOLOGICAL PSYCHIATRY
- Allopregnanolone Increases the Number of Dopaminergic Neurons in Substantia Nigra of a Triple Transgenic Mouse Model of Alzheimer's Disease
- (2012) Chenyou Sun et al. Current Alzheimer Research
- Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
- (2012) Keiichi Inoue et al. Molecular Neurodegeneration
- Coherence and frequency in the reticular activating system (RAS)
- (2012) Edgar Garcia-Rill et al. SLEEP MEDICINE REVIEWS
- National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
- (2011) Thomas J. Montine et al. ACTA NEUROPATHOLOGICA
- Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
- (2011) Heiko Braak et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
- (2011) Melissa E Murray et al. LANCET NEUROLOGY
- The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease
- (2011) Sergey Kalinin et al. NEUROBIOLOGY OF AGING
- Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice
- (2011) Chanpreet Singh et al. NEUROBIOLOGY OF AGING
- Correlations between cortical and subcortical tau pathology
- (2011) J. Attems et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- 7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease
- (2011) Latha Devi et al. NEUROPSYCHOPHARMACOLOGY
- The pathological process underlying Alzheimer’s disease in individuals under thirty
- (2010) Heiko Braak et al. ACTA NEUROPATHOLOGICA
- The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project
- (2010) Onofre Combarros et al. BMC Medical Genetics
- Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus
- (2010) Samantha Tang et al. BRAIN RESEARCH
- Cyclic-AMP response element binding protein and tau are involved in the neuroprotective mechanisms of nerve growth factor during focal cerebral ischemia/reperfusion in rats
- (2010) Zheng-Hong Zhang et al. JOURNAL OF CLINICAL NEUROSCIENCE
- A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect
- (2010) Xia Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity
- (2010) Scott E. Counts et al. JOURNAL OF NEUROCHEMISTRY
- Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex
- (2010) Eoin N. McNamee et al. NEUROPHARMACOLOGY
- Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease
- (2010) M. Morawski et al. NEUROSCIENCE
- Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
- (2010) M. T. Heneka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease
- (2010) J. M. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocyte-Derived MCP-1 Mediates Neuroprotective Effects of Noradrenaline
- (2009) J. L. M. Madrigal et al. JOURNAL OF NEUROSCIENCE
- The locus coeruleus and noradrenergic modulation of cognition
- (2009) Susan J. Sara NATURE REVIEWS NEUROSCIENCE
- Somatostatin and Alzheimer's disease
- (2008) E. Burgos-Ramos et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Glutathione: Overview of its protective roles, measurement, and biosynthesis
- (2008) Henry Jay Forman et al. MOLECULAR ASPECTS OF MEDICINE
- Seeding Neuritic Plaques from the Distance: A Possible Role for Brainstem Neurons in the Development of Alzheimer’s Disease Pathology
- (2008) Zoia Muresan et al. Neurodegenerative Diseases
- Noradrenaline provides long-term protection to dopaminergic neurons by reducing oxidative stress
- (2003) Jean-Denis Troadec et al. JOURNAL OF NEUROCHEMISTRY
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